Barg, Sebastian

Functional, metabolic and transcriptional maturation of human pancreatic islets derived from stem cells

Balboa, D., Barsby, T., Lithovius, V., Saarimäki-Vire, J., Omar-Hmeadi, M., Dyachok, O., Montaser, H., Lund, P.-E., Yang, M., Ibrahim, H., et al. (2022) · Nature Biotechnology

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 433

Fast insulin secretion reflects exocytosis of docked granules in mouse pancreatic B-cells

Olofsson, C. S., Göpel, S. O., Barg, S., Galvanovskis, J., Ma, X., Salehi, A., Rorsman, P., & Eliasson, L. (2002) · Pflügers Archiv

Pancreatic function and diabetesCellular transport and secretion

Cited by 290

The voltage sensitive Lc-type Ca 2+ channel is functionally coupled to the exocytotic machinery

Wiser, O., Trus, M., Hernández, A., Renström, E., Barg, S., Rorsman, P., & Atlas, D. (1999) · Proceedings of the National Academy of Sciences

Cellular transport and secretionIon channel regulation and function

Cited by 284

SUR1 Regulates PKA-independent cAMP-induced Granule Priming in Mouse Pancreatic B-cells

Eliasson, L., Ma, X., Renström, E., Barg, S., Berggren, P.-O., Galvanovskis, J., Gromada, J., Jing, X., Lundquist, I., Salehi, A., et al. (2003) · The Journal of General Physiology

Pancreatic function and diabetesCellular transport and secretion

Cited by 257

Fast Exocytosis with Few Ca2+ Channels in Insulin-Secreting Mouse Pancreatic B Cells

Barg, S., Ma, X., Eliasson, L., Galvanovskis, J., Göpel, S. O., Obermüller, S., Platzer, J., Renström, E., Trus, M., Atlas, D., et al. (2001) · Biophysical Journal

Pancreatic function and diabetesCellular transport and secretion

Cited by 255

Regulation of glucagon release in mouse α‐cells by KATP channels and inactivation of TTX‐sensitive Na+ channels

Göpel, S. O., Kanno, T., Barg, S., Weng, X. ‐., Gromada, J., & Rorsman, P. (2000) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 229

A Subset of 50 Secretory Granules in Close Contact With l-Type Ca2+ Channels Accounts for First-Phase Insulin Secretion in Mouse β-Cells

Barg, S., Eliasson, L., Renström, E., & Rorsman, P. (2002) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 227

Voltage‐gated and resting membrane currents recorded from B‐cells in intact mouse pancreatic islets

Göpel, S., Kanno, T., Barg, S., Galvanovskis, J., & Rorsman, P. (1999) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 226

Delay between Fusion Pore Opening and Peptide Release from Large Dense-Core Vesicles in Neuroendocrine Cells

Barg, S., Olofsson, C. S., Schriever-Abeln, J., Wendt, A., Gebre-Medhin, S., Renström, E., & Rorsman, P. (2002) · Neuron

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 210

Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting alpha-cells.

Barg, S., Galvanovskis, J., Göpel, S. O., Rorsman, P., & Eliasson, L. (2000) · Diabetes

Pancreatic function and diabetesCellular transport and secretion

Cited by 209

Priming of insulin granules for exocytosis by granular Cl(-) uptake and acidification

Barg, S., Huang, P., Eliasson, L., Nelson, D. J., Obermüller, S., Rorsman, P., Thévenod, F., & Renström, E. (2001) · Journal of Cell Science

Pancreatic function and diabetesCellular transport and secretion

Cited by 194

Selective nucleotide-release from dense-core granules in insulin-secreting cells

Obermüller, S., Lindqvist, A., Karanauskaite, J., Galvanovskis, J., Rorsman, P., & Barg, S. (2005) · Journal of Cell Science

Cellular transport and secretionPancreatic function and diabetes

Cited by 138

Activation of Ca2+-Dependent K+ Channels Contributes to Rhythmic Firing of Action Potentials in Mouse Pancreatic β Cells

Göpel, S. O., Kanno, T., Barg, S., Eliasson, L., Galvanovskis, J., Renström, E., & Rorsman, P. (1999) · The Journal of General Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 137

Contact-induced clustering of syntaxin and munc18 docks secretory granules at the exocytosis site

Gandasi, N. R., & Barg, S. (2014) · Nature Communications

Cellular transport and secretionExtracellular vesicles in disease

Cited by 130

Glucose-Dependent Granule Docking Limits Insulin Secretion and Is Decreased in Human Type 2 Diabetes

Gandasi, N. R., Yin, P., Omar-Hmeadi, M., Ottosson Laakso, E., Vikman, P., & Barg, S. (2018) · Cell Metabolism

Pancreatic function and diabetesCellular transport and secretion

Cited by 115

Multisite regulation of insulin secretion by cAMP-increasing agonists: evidence that glucagon-like peptide 1 and glucagon act via distinct receptors

Gromada, J., Ding, W.-G., Barg, S., Renström, E., & Rorsman, P. (1997) · Pfl�gers Archiv European Journal of Physiology

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 110

Paracrine control of α-cell glucagon exocytosis is compromised in human type-2 diabetes

Omar-Hmeadi, M., Lund, P.-E., Gandasi, N. R., Tengholm, A., & Barg, S. (2020) · Nature Communications

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 105

Large dense-core vesicle exocytosis in pancreatic β-cells monitored by capacitance measurements

Kanno, T., Ma, X., Barg, S., Eliasson, L., Galvanovskis, J., Göpel, S., Larsson, M., Renström, E., & Rorsman, P. (2004) · Methods

Pancreatic function and diabetesCellular transport and secretion

Cited by 44

Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial‐like ATP‐sensitive K+ (KATP) conductance in rat pancreatic A‐cells

Høy, M., Olsen, H. L., Bokvist, K., Buschard, K., Barg, S., Rorsman, P., & Gromada, J. (2000) · The Journal of Physiology

Pancreatic function and diabetesIon channel regulation and function

Cited by 32

PtdIns(4,5)P2 is not required for secretory granule docking

Omar‐Hmeadi, M., Gandasi, N. R., & Barg, S. (2018) · Traffic

Cellular transport and secretionPancreatic function and diabetes

Cited by 18

Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosis

Chouaib, A. A., Chang, H.-F., Khamis, O. M., Alawar, N., Echeverry, S., Demeersseman, L., Elizarova, S., Daniel, J. A., Tian, Q., Lipp, P., et al. (2025) · Nature Communications

Cell Image Analysis TechniquesCellular transport and secretion

Cited by 11

Highly adaptable deep-learning platform for automated detection and analysis of vesicle exocytosis

Chouaib, A. A., Chang, H.-F., Khamis, O. M., Echeverry, S., Demeersseman, L., Elizarova, S., Daniel, J. A., Valitutti, S., Barg, S., Pape, C., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Cell Image Analysis TechniquesCellular transport and secretion

Cited by 1