Gladwin, Mark T.

Nitrite mediates cytoprotection after ischemia/reperfusion by modulating mitochondrial function

Shiva, S., & Gladwin, M. T. (2009) · Basic Research in Cardiology

Cardiac Ischemia and ReperfusionNitric Oxide and Endothelin Effects

Cited by 91

Deconstructing endothelial dysfunction: soluble guanylyl cyclase oxidation and the NO resistance syndrome

Gladwin, M. T. (2006) · Journal of Clinical Investigation

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 85

Sulfite Oxidase Catalyzes Single-Electron Transfer at Molybdenum Domain to Reduce Nitrite to Nitric Oxide

Wang, J., Krizowski, S., Fischer-Schrader, K., Niks, D., Tejero, J., Sparacino-Watkins, C., Wang, L., Ragireddy, V., Frizzell, S., Kelley, E. E., et al. (2015) · Antioxidants & Redox Signaling

Metalloenzymes and iron-sulfur proteinsMetal-Catalyzed Oxygenation Mechanisms

Cited by 84

Low-dose intravenous nitrite improves hemodynamics in a canine model of acute pulmonary thromboembolism

Dias-Junior, C. A. C., Gladwin, M. T., & Tanus-Santos, J. E. (2006) · Free Radical Biology and Medicine

Pulmonary Hypertension Research and TreatmentsNitric Oxide and Endothelin Effects

Cited by 82

Effects of nitrite on modulating ROS generation following ischemia and reperfusion

Raat, N. J. H., Shiva, S., & Gladwin, M. T. (2009) · Advanced Drug Delivery Reviews

Cardiac Ischemia and ReperfusionNitric Oxide and Endothelin Effects

Cited by 79

Mechanisms of Human Erythrocytic Bioactivation of Nitrite

Liu, C., Wajih, N., Liu, X., Basu, S., Janes, J., Marvel, M., Keggi, C., Helms, C. C., Lee, A. N., Belanger, A. M., et al. (2015) · Journal of Biological Chemistry

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 76

14-3-3 Binding and phosphorylation of neuroglobin during hypoxia modulate six-to-five heme pocket coordination and rate of nitrite reduction to nitric oxide

Jayaraman, T., Tejero, J., Chen, B. B., Blood, A. B., Frizzell, S., Shapiro, C., Tiso, M., Hood, B. L., Wang, X., Zhao, X., et al. (2011) · Journal of Biological Chemistry

Hemoglobin structure and functionHeme Oxygenase-1 and Carbon Monoxide

Cited by 73

Nitrite Reductase Activity of Nonsymbiotic Hemoglobins from Arabidopsis thaliana

Tiso, M., Tejero, J., Kenney, C., Frizzell, S., & Gladwin, M. T. (2012) · Biochemistry

Hemoglobin structure and functionHeme Oxygenase-1 and Carbon Monoxide

Cited by 69

Nitrite signaling in pulmonary hypertension: mechanisms of bioactivation, signaling, and therapeutics

Bueno, M., Wang, J., Mora, A. L., & Gladwin, M. T. (2013) · Antioxidants & Redox Signaling

Nitric Oxide and Endothelin EffectsPulmonary Hypertension Research and Treatments

Cited by 68

Sodium nitrite promotes regional blood flow in patients with sickle cell disease: a phase I/II study

Mack, A. K., McGowan II, V. R., Tremonti, C. K., Ackah, D., Barnett, C., Machado, R. F., Gladwin, M. T., & Kato, G. J. (2008) · British Journal of Haematology

Hemoglobinopathies and Related DisordersNitric Oxide and Endothelin Effects

Cited by 64

Nitrite as an intrinsic signaling molecule

Gladwin, M. T. (2005) · Nature Chemical Biology

Nitric Oxide and Endothelin EffectsRedox biology and oxidative stress

Cited by 62

Nitrite modulates bacterial antibiotic susceptibility and biofilm formation in association with airway epithelial cells

Zemke, A. C., Shiva, S., Burns, J. L., Moskowitz, S. M., Pilewski, J. M., Gladwin, M. T., & Bomberger, J. M. (2014) · Free Radical Biology and Medicine

Bacterial biofilms and quorum sensingCystic Fibrosis Research Advances

Cited by 61

Role of the Red Blood Cell in Nitric Oxide Homeostasis and Hypoxic Vasodilation

Gladwin, M. T. (2007) · Advances in Experimental Medicine and Biology

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 59

Depletion of circulating blood NOS3 increases severity of myocardial infarction and left ventricular dysfunction

Merx, M. W., Gorressen, S., Sandt, A. M., Cortese-Krott, M. M., Ohlig, J., Stern, M., Rassaf, T., Gödecke, A., Gladwin, M. T., & Kelm, M. (2014) · Basic Research in Cardiology

Nitric Oxide and Endothelin EffectsCardiac Ischemia and Reperfusion

Cited by 53

Haptoglobin improves shock, lung injury, and survival in canine pneumonia

Remy, K. E., Cortés-Puch, I., Solomon, S. B., Sun, J., Pockros, B. M., Feng, J., Lertora, J. J., Hantgan, R. R., Liu, X., Perlegas, A., et al. (2018) · JCI Insight

Sepsis Diagnosis and TreatmentHemoglobin structure and function

Cited by 49

Hemoglobin as a Nitrite Reductase Regulating Red Cell–Dependent Hypoxic Vasodilation

Gladwin, M. T. (2005) · American Journal of Respiratory Cell and Molecular Biology

Hemoglobin structure and functionNitric Oxide and Endothelin Effects

Cited by 42

Elevated Pulse Pressure is Associated with Hemolysis, Proteinuria and Chronic Kidney Disease in Sickle Cell Disease

Novelli, E. M., Hildesheim, M., Rosano, C., Vanderpool, R., Simon, M., Kato, G. J., & Gladwin, M. T. (2014) · PLoS ONE

Hemoglobinopathies and Related DisordersBlood Pressure and Hypertension Studies

Cited by 38

Effects of nitric oxide and its congeners on sickle red blood cell deformability

Belanger, A. M., Keggi, C., Kanias, T., Gladwin, M. T., & Kim‐Shapiro, D. B. (2015) · Transfusion

Hemoglobinopathies and Related DisordersBlood properties and coagulation

Cited by 37

Whole-genome association analyses of sleep-disordered breathing phenotypes in the NHLBI TOPMed program

Cade, B. E., Lee, J., Sofer, T., Wang, H., Zhang, M., Chen, H., Gharib, S. A., Gottlieb, D. J., Guo, X., Lane, J. M., et al. (2021) · Genome Medicine

Obstructive Sleep Apnea ResearchGenetic Associations and Epidemiology

Cited by 33

Therapeutics Targeting of Dysregulated Redox Equilibrium and Endothelial Dysfunction

Risbano, M. G., & Gladwin, M. T. (2013) · Handbook of Experimental Pharmacology

Pulmonary Hypertension Research and TreatmentsNitric Oxide and Endothelin Effects

Cited by 32

Nebulized nitrite protects rat lung grafts from ischemia reperfusion injury

Okamoto, T., Tang, X., Janocha, A., Farver, C. F., Gladwin, M. T., & McCurry, K. R. (2013) · The Journal of Thoracic and Cardiovascular Surgery

Transplantation: Methods and OutcomesOrgan Transplantation Techniques and Outcomes

Cited by 22

Evidence mounts that red cells and deoxyhemoglobin can reduce nitrite to bioactive NO to mediate intravascular endocrine NO signaling: commentary on “Anti-platelet effects of dietary nitrate in healthy volunteers: involvement of cGMP and influence of sex”

Corti, P., Tejero, J., & Gladwin, M. T. (2013) · Free Radical Biology and Medicine

Nitric Oxide and Endothelin EffectsLaser Applications in Dentistry and Medicine

Cited by 13