Sheng, Morgan
Broad Institute
70 papers on CoChatORCID 0000-0002-8703-5366
Most cited papers
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Relative and Absolute Quantification of Postsynaptic Density Proteome Isolated from Rat Forebrain and Cerebellum
Cheng, D., Hoogenraad, C. C., Rush, J., Ramm, E., Schlager, M. A., Duong, D. M., Xu, P., Wijayawardana, S. R., Hanfelt, J., Nakagawa, T., et al. (2006) · Molecular & Cellular Proteomics
Advanced Proteomics Techniques and ApplicationsNeuroscience and Neuropharmacology Research
Cited by 510
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Differential roles of NR2A- and NR2B-containing NMDA receptors in Ras-ERK signaling and AMPA receptor trafficking
Kim, M. J., Dunah, A. W., Wang, Y. T., & Sheng, M. (2005) · Neuron
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 494
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Targeted disruption of NMDA receptor 1 gene abolishes NMDA response and results in neonatal death
Forrest, D., Yuzaki, M., Soares, H. D., Ng, L., Luk, D. C., Sheng, M., Stewart, C. L., Morgan, J. I., Connor, J. A., & Curran, T. (1994) · Neuron
Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism
Cited by 491
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Semiquantitative Proteomic Analysis of Rat Forebrain Postsynaptic Density Fractions by Mass Spectrometry
Peng, J., Kim, M. J., Cheng, D., Duong, D. M., Gygi, S. P., & Sheng, M. (2004) · Journal of Biological Chemistry
Advanced Proteomics Techniques and ApplicationsNeuroscience and Neuropharmacology Research
Cited by 473
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Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy
Wu, T., Dejanovic, B., Gandham, V. D., Gogineni, A., Edmonds, R., Schauer, S., Srinivasan, K., Huntley, M. A., Wang, Y., Wang, T.-M., et al. (2019) · Cell Reports
Alzheimer's disease research and treatmentsComplement system in diseases
Cited by 466
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Clathrin adaptor AP2 and NSF interact with overlapping sites of GluR2 and play distinct roles in AMPA receptor trafficking and hippocampal LTD
Lee, S. H., Liu, L., Wang, Y. T., & Sheng, M. (2002) · Neuron
Neuroscience and Neuropharmacology ResearchCellular transport and secretion
Cited by 441
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TREM2, microglia, and neurodegenerative diseases
Yeh, F. L., Hansen, D. V., & Sheng, M. (2017) · Trends in Molecular Medicine
Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments
Cited by 440
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Synapses and Alzheimer's Disease
Sheng, M., Sabatini, B. L., & Sudhof, T. C. (2012) · Cold Spring Harbor Perspectives in Biology
Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research
Cited by 436
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Nuclear translocation and transcription regulation by the membrane-associated guanylate kinase CASK/LIN-2
Hsueh, Y.-P., Wang, T.-F., Yang, F.-C., & Sheng, M. (2000) · Nature
Developmental Biology and Gene RegulationGenetics and Neurodevelopmental Disorders
Cited by 355
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Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1
Hung, A. Y., Futai, K., Sala, C., Valtschanoff, J. G., Ryu, J., Woodworth, M. A., Kidd, F. L., Sung, C. C., Miyakawa, T., Bear, M. F., et al. (2008) · The Journal of Neuroscience
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 350
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Extracellular interactions between GluR2 and N-cadherin in spine regulation
Saglietti, L., Dequidt, C., Kamieniarz, K., Rousset, M.-C., Valnegri, P., Thoumine, O., Beretta, F., Fagni, L., Choquet, D., Sala, C., et al. (2007) · Neuron
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 341
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Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer’s disease mouse models
Dejanovic, B., Wu, T., Tsai, M.-C., Graykowski, D., Gandham, V. D., Rose, C. M., Bakalarski, C. E., Ngu, H., Wang, Y., Pandey, S., et al. (2022) · Nature Aging
Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments
Cited by 341
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Leukocyte common antigen-related phosphatase is a functional receptor for chondroitin sulfate proteoglycan axon growth inhibitors
Fisher, D., Xing, B., Dill, J., Li, H., Hoang, H. H., Zhao, Z., Yang, X.-L., Bachoo, R., Cannon, S., Longo, F. M., et al. (2011) · The Journal of Neuroscience
Nerve injury and regenerationProteoglycans and glycosaminoglycans research
Cited by 312
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Aβ1-42 inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β
Jo, J., Whitcomb, D. J., Olsen, K. M., Kerrigan, T. L., Lo, S.-C., Bru-Mercier, G., Dickinson, B., Scullion, S., Sheng, M., Collingridge, G., et al. (2011) · Nature Neuroscience
Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research
Cited by 305
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Trem2 restrains the enhancement of tau accumulation and neurodegeneration by β-amyloid pathology
Lee, S.-H., Meilandt, W. J., Xie, L., Gandham, V. D., Ngu, H., Barck, K. H., Rezzonico, M. G., Imperio, J., Lalehzadeh, G., Huntley, M. A., et al. (2021) · Neuron
Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms
Cited by 300
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Tyrosine phosphorylation of GluR2 is required for insulin-stimulated AMPA receptor endocytosis and LTD
Ahmadian, G., Ju, W., Liu, L., Wyszynski, M., Lee, S. H., Dunah, A. W., Taghibiglou, C., Wang, Y., Lu, J., Wong, T. P., et al. (2004) · The EMBO Journal
Neuroscience and Neuropharmacology ResearchCellular transport and secretion
Cited by 296
- Verified · note
Characterization of the Shank Family of Synaptic Proteins
Lim, S., Naisbitt, S., Yoon, J., Hwang, J.-I., Suh, P.-G., Sheng, M., & Kim, E. (1999) · Journal of Biological Chemistry
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 295
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Inhibition of Dendritic Spine Morphogenesis and Synaptic Transmission by Activity-Inducible Protein Homer1a
Sala, C., Futai, K., Yamamoto, K., Worley, P. F., Hayashi, Y., & Sheng, M. (2003) · The Journal of Neuroscience
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 288
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Synaptic Accumulation of PSD-95 and Synaptic Function Regulated by Phosphorylation of Serine-295 of PSD-95
Kim, M. J., Futai, K., Jo, J., Hayashi, Y., Cho, K., & Sheng, M. (2007) · Neuron
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 278
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Deconstruction for Reconstruction: The Role of Proteolysis in Neural Plasticity and Disease
Bingol, B., & Sheng, M. (2011) · Neuron
Neuroscience and Neuropharmacology ResearchUbiquitin and proteasome pathways
Cited by 275
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Activity-Dependent Redistribution and Essential Role of Cortactin in Dendritic Spine Morphogenesis
Hering, H., & Sheng, M. (2003) · The Journal of Neuroscience
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 269
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Autophosphorylated CaMKIIα Acts as a Scaffold to Recruit Proteasomes to Dendritic Spines
Bingol, B., Wang, C.-F., Arnott, D., Cheng, D., Peng, J., & Sheng, M. (2010) · Cell
Ubiquitin and proteasome pathwaysNeuroscience and Neuropharmacology Research
Cited by 268
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Quaternary Structure, Protein Dynamics, and Synaptic Function of SAP97 Controlled by L27 Domain Interactions
Nakagawa, T., Futai, K., Lashuel, H. A., Lo, I., Okamoto, K., Walz, T., Hayashi, Y., & Sheng, M. (2004) · Neuron
Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders
Cited by 250
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Mass of the postsynaptic density and enumeration of three key molecules
Chen, X., Vinade, L., Leapman, R. D., Petersen, J. D., Nakagawa, T., Phillips, T. M., Sheng, M., & Reese, T. S. (2005) · Proceedings of the National Academy of Sciences
Neuroscience and Neuropharmacology ResearchProtein Kinase Regulation and GTPase Signaling
Cited by 236
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