Sheng, Morgan

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

Trubetskoy, V., Pardiñas, A. F., Qi, T., Panagiotaropoulou, G., Awasthi, S., Bigdeli, T. B., Bryois, J., Chen, C.-Y., Dennison, C. A., Hall, L. S., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 2,964

Microglia in Alzheimer’s disease

Hansen, D. V., Hanson, J. E., & Sheng, M. (2018) · Journal of Cell Biology

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 1,935

The importance of dendritic mitochondria in the morphogenesis and plasticity of spines and synapses

Li, Z., Okamoto, K.-I., Hayashi, Y., & Sheng, M. (2004) · Cell

Mitochondrial Function and PathologyNeuroscience and Neuropharmacology Research

Cited by 1,498

Changing subunit composition of heteromeric NMDA receptors during development of rat cortex

Sheng, M., Cummings, J., Roldan, L. A., Jan, Y. N., & Jan, L. Y. (1994) · Nature

Neuroscience and Neuropharmacology ResearchAmino Acid Enzymes and Metabolism

Cited by 1,377

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

Chang, D., Nalls, M. A., Hallgrímsdóttir, I. B., Hunkapiller, J., van der Brug, M., Cai, F., International Parkinson's Disease Genomics Consortium, 23andMe Research Team, Kerchner, G. A., Ayalon, G., et al. (2017) · Nature Genetics

Parkinson's Disease Mechanisms and TreatmentsGenetic Associations and Epidemiology

Cited by 1,112

Shank, a Novel Family of Postsynaptic Density Proteins that Binds to the NMDA Receptor/PSD-95/GKAP Complex and Cortactin

Naisbitt, S., Kim, E., Tu, J. C., Xiao, B., Sala, C., Valtschanoff, J., Weinberg, R. J., Worley, P. F., & Sheng, M. (1999) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 1,009

The Postsynaptic Architecture of Excitatory Synapses: A More Quantitative View

Sheng, M., & Hoogenraad, C. C. (2007) · Annual Review of Biochemistry

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 1,003

Dentritic spines : structure, dynamics and regulation

Hering, H., & Sheng, M. (2001) · Nature Reviews Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 961

TREM2 Binds to Apolipoproteins, Including APOE and CLU/APOJ, and Thereby Facilitates Uptake of Amyloid-Beta by Microglia

Yeh, F. L., Wang, Y., Tom, I., Gonzalez, L. C., & Sheng, M. (2016) · Neuron

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 943

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

Koopmans, F., van Nierop, P., Andres-Alonso, M., Byrnes, A., Cijsouw, T., Coba, M. P., Cornelisse, L. N., Farrell, R. J., Goldschmidt, H. L., Howrigan, D. P., et al. (2019) · Neuron

Biomedical Text Mining and OntologiesBioinformatics and Genomic Networks

Cited by 938

Tbr1 regulates differentiation of the preplate and layer 6

Hevner, R. F., Shi, L., Justice, N., Hsueh, Y.-P., Sheng, M., Smiga, S., Bulfone, A., Goffinet, A. M., Campagnoni, A. T., & Rubenstein, J. L. R. (2001) · Neuron

Neurogenesis and neuroplasticity mechanismsDevelopmental Biology and Gene Regulation

Cited by 857

The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy

Bingol, B., Tea, J. S., Phu, L., Reichelt, M., Bakalarski, C. E., Song, Q., Foreman, O., Kirkpatrick, D. S., & Sheng, M. (2014) · Nature

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 855

Interaction between the C terminus of NMDA receptor subunits and multiple members of the PSD-95 family of membrane-associated guanylate kinases

Niethammer, M., Kim, E., & Sheng, M. (1996) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 750

Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125b and miR-132

Edbauer, D., Neilson, J. R., Foster, K. A., Wang, C.-F., Seeburg, D. P., Batterton, M. N., Tada, T., Dolan, B. M., Sharp, P. A., & Sheng, M. (2010) · Neuron

Genetics and Neurodevelopmental DisordersMicroRNA in disease regulation

Cited by 735

Postsynaptic signaling and plasticity mechanisms

Sheng, M., & Kim, M. J. (2002) · Science

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 731

Regulation of Dendritic Spine Morphology and Synaptic Function by Shank and Homer

Sala, C., Piëch, V., Wilson, N. R., Passafaro, M., Liu, G., & Sheng, M. (2001) · Neuron

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 716

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

Carlén, M., Meletis, K., Siegle, J. H., Cardin, J. A., Futai, K., Vierling-Claassen, D., Rühlmann, C., Jones, S. R., Deisseroth, K., Sheng, M., et al. (2012) · Molecular Psychiatry

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 669

Subunit-specific temporal and spatial patterns of AMPA receptor exocytosis in hippocampal neurons

Passafaro, M., Piëch, V., & Sheng, M. (2001) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 655

Molecular mechanisms of dendritic spine morphogenesis

Tada, T., & Sheng, M. (2006) · Current Opinion in Neurobiology

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 615

The Postsynaptic Organization of Synapses

Sheng, M., & Kim, E. (2011) · Cold Spring Harbor Perspectives in Biology

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 603

Competitive binding of α-actinin and calmodulin to the NMDA receptor

Wyszynski, M., Lin, J., Rao, A., Nigh, E., Beggs, A. H., Craig, A. M., & Sheng, M. (1997) · Nature

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 596

The Shank family of scaffold proteins

Sheng, M., & Kim, E. (2000) · Journal of Cell Science

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 578

Changes in the Synaptic Proteome in Tauopathy and Rescue of Tau-Induced Synapse Loss by C1q Antibodies

Dejanovic, B., Huntley, M. A., De Mazière, A., Meilandt, W. J., Wu, T., Srinivasan, K., Jiang, Z., Gandham, V., Friedman, B. A., Ngu, H., et al. (2018) · Neuron

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 517

GKAP, a Novel Synaptic Protein That Interacts with the Guanylate Kinase-like Domain of the PSD-95/SAP90 Family of Channel Clustering Molecules

Kim, E., Naisbitt, S., Hsueh, Y.-P., Rao, A., Rothschild, A., Craig, A. M., & Sheng, M. (1997) · The Journal of Cell Biology

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 516