Jones, Stephen N.

Regulation of p53 stability by Mdm2

Kubbutat, M. H. G., Jones, S. N., & Vousden, K. H. (1997) · Nature

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 3,312

Requirement of JNK for Stress- Induced Activation of the Cytochrome c-Mediated Death Pathway

Tournier, C., Hess, P., Yang, D. D., Xu, J., Turner, T. K., Nimnual, A., Bar-Sagi, D., Jones, S. N., Flavell, R. A., & Davis, R. J. (2000) · Science

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 1,728

p53 mutant mice that display early ageing-associated phenotypes

Tyner, S. D., Venkatachalam, S., Choi, J., Jones, S., Ghebranious, N., Igelmann, H., Lu, X., Soron, G., Cooper, B., Brayton, C., et al. (2002) · Nature

Genetics, Aging, and Longevity in Model OrganismsCancer-related Molecular Pathways

Cited by 1,459

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53

Jones, S. N., Roe, A. E., Donehower, L. A., & Bradley, A. (1995) · Nature

Cancer-related Molecular PathwaysDevelopmental Biology and Gene Regulation

Cited by 1,280

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis

Jones, S. N., Hancock, A. R., Vogel, H., Donehower, L. A., & Bradley, A. (1998) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 386

Requirement of the JIP1 scaffold protein for stress-induced JNK activation

Whitmarsh, A. J., Kuan, C.-Y., Kennedy, N. J., Kelkar, N., Haydar, T. F., Mordes, J. P., Appel, M., Rossini, A. A., Jones, S. N., Flavell, R. A., et al. (2001) · Genes & Development

Protein Kinase Regulation and GTPase SignalingNF-κB Signaling Pathways

Cited by 238

Phosphorylation of Serine 18 Regulates Distinct p53 Functions in Mice

Sluss, H. K., Armata, H., Gallant, J., & Jones, S. N. (2004) · Molecular and Cellular Biology

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 152

NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma

Zhao, S., Kurenbekova, L., Gao, Y., Roos, A., Creighton, C. J., Rao, P., Hicks, J., Man, T.-K., Lau, C., Brown, A. M. C., et al. (2015) · Oncogene

Sarcoma Diagnosis and TreatmentWnt/β-catenin signaling in development and cancer

Cited by 139

ATM Phosphorylation of Mdm2 Ser394 Regulates the Amplitude and Duration of the DNA Damage Response in Mice

Gannon, H. S., Woda, B. A., & Jones, S. N. (2012) · Cancer Cell

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 105

An Alternative Splice Form of Mdm2 Induces p53-independent Cell Growth and Tumorigenesis

Steinman, H. A., Burstein, E., Lengner, C., Gosselin, J., Pihan, G., Duckett, C. S., & Jones, S. N. (2004) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysRNA Research and Splicing

Cited by 96

Mdm2–p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin

Gannon, H. S., Donehower, L. A., Lyle, S., & Jones, S. N. (2011) · Developmental Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 87

Elevated Mdm2 expression induces chromosomal instability and confers a survival and growth advantage to B cells

Wang, P., Lushnikova, T., Odvody, J., Greiner, T. C., Jones, S. N., & Eischen, C. M. (2008) · Oncogene

Cancer-related Molecular PathwaysLymphoma Diagnosis and Treatment

Cited by 86

Phosphorylation and Degradation of MdmX Is Inhibited by Wip1 Phosphatase in the DNA Damage Response

Zhang, X., Lin, L., Guo, H., Yang, J., Jones, S. N., Jochemsen, A., & Lu, X. (2009) · Cancer Research

Cancer-related Molecular PathwaysProtein Tyrosine Phosphatases

Cited by 67

MdmX Promotes Bipolar Mitosis To Suppress Transformation and Tumorigenesis in p53-Deficient Cells and Mice

Matijasevic, Z., Steinman, H. A., Hoover, K., & Jones, S. N. (2008) · Molecular and Cellular Biology

Cancer-related Molecular PathwaysMicrotubule and mitosis dynamics

Cited by 58

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

Moore, L., Venkatachalam, S., Vogel, H., Watt, J. C., Wu, C.-L., Steinman, H., Jones, S. N., & Donehower, L. A. (2003) · Oncogene

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 48

MdmX regulates transformation and chromosomal stability in p53-deficient cells

Matijasevic, Z., Krzywicka-Racka, A., Sluder, G., & Jones, S. N. (2008) · Cell Cycle

Cancer-related Molecular PathwaysMicrotubule and mitosis dynamics

Cited by 34