Huttenhower, Curtis

Complex host genetics influence the microbiome in inflammatory bowel disease

Knights, D., Silverberg, M. S., Weersma, R. K., Gevers, D., Dijkstra, G., Huang, H., Tyler, A. D., van Sommeren, S., Imhann, F., Stempak, J. M., et al. (2014) · Genome Medicine

Gut microbiota and healthInflammatory Bowel Disease

Cited by 418

The gut microbiome modulates the protective association between a Mediterranean diet and cardiometabolic disease risk

Wang, D. D., Nguyen, L. H., Li, Y., Yan, Y., Ma, W., Rinott, E., Ivey, K. L., Shai, I., Willett, W. C., Hu, F. B., et al. (2021) · Nature Medicine

Gut microbiota and healthNutritional Studies and Diet

Cited by 386

Tryptophan Biosynthesis Protects Mycobacteria from CD4 T-Cell-Mediated Killing

Zhang, Y. J., Reddy, M. C., Ioerger, T. R., Rothchild, A. C., Dartois, V., Schuster, B. M., Trauner, A., Wallis, D., Galaviz, S., Huttenhower, C., et al. (2013) · Cell

Tuberculosis Research and EpidemiologyImmune responses and vaccinations

Cited by 351

Inflammatory Bowel Disease as a Model for Translating the Microbiome

Huttenhower, C., Kostic, A. D., & Xavier, R. J. (2014) · Immunity

Gut microbiota and healthInflammatory Bowel Disease

Cited by 332

Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue

Mehta, R. S., Nishihara, R., Cao, Y., Song, M., Mima, K., Qian, Z. R., Nowak, J. A., Kosumi, K., Hamada, T., Masugi, Y., et al. (2017) · JAMA Oncology

Nutritional Studies and DietGut microbiota and health

Cited by 325

A bacterial bile acid metabolite modulates Treg activity through the nuclear hormone receptor NR4A1

Li, W., Hang, S., Fang, Y., Bae, S., Zhang, Y., Zhang, M., Wang, G., McCurry, M. D., Bae, M., Paik, D., et al. (2021) · Cell Host & Microbe

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 306

Biogeography of the intestinal mucosal and lumenal microbiome in the rhesus macaque

Yasuda, K., Oh, K., Ren, B., Tickle, T. L., Franzosa, E. A., Wachtman, L. M., Miller, A. D., Westmoreland, S. V., Mansfield, K. G., Vallender, E. J., et al. (2015) · Cell Host & Microbe

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 298

Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans

Vatanen, T., Kostic, A. D., d’Hennezel, E., Siljander, H., Franzosa, E. A., Yassour, M., Kolde, R., Vlamakis, H., Arthur, T. D., Hämäläinen, A.-M., et al. (2016) · Cell

Gut microbiota and healthImmune Response and Inflammation

Cited by 298

Fusobacterium nucleatum in colorectal carcinoma tissue according to tumor location

Mima, K., Cao, Y., Chan, A. T., Qian, Z. R., Nowak, J. A., Masugi, Y., Shi, Y., Song, M., da Silva, A., Gu, M., et al. (2016) · Clinical and Translational Gastroenterology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 284

Stability of the human faecal microbiome in a cohort of adult men

Mehta, R. S., Abu-Ali, G. S., Drew, D. A., Lloyd-Price, J., Subramanian, A., Lochhead, P., Joshi, A. D., Ivey, K. L., Khalili, H., Brown, G. T., et al. (2018) · Nature Microbiology

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 273

Passing Messages between Biological Networks to Refine Predicted Interactions

Glass, K., Huttenhower, C., Quackenbush, J., & Yuan, G.-C. (2013) · PLoS ONE

Gene Regulatory Network AnalysisBioinformatics and Genomic Networks

Cited by 266

Experimental design and quantitative analysis of microbial community multiomics

Mallick, H., Ma, S., Franzosa, E. A., Vatanen, T., Morgan, X. C., & Huttenhower, C. (2017) · Genome Biology

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 192

Host genetic variation and its microbiome interactions within the Human Microbiome Project

Kolde, R., Franzosa, E. A., Rahnavard, G., Hall, A. B., Vlamakis, H., Stevens, C., Daly, M. J., Xavier, R. J., & Huttenhower, C. (2018) · Genome Medicine

Gut microbiota and healthGenetic Associations and Epidemiology

Cited by 182

Population structure discovery in meta-analyzed microbial communities and inflammatory bowel disease using MMUPHin

Ma, S., Shungin, D., Mallick, H., Schirmer, M., Nguyen, L. H., Kolde, R., Franzosa, E., Vlamakis, H., Xavier, R., & Huttenhower, C. (2022) · Genome biology

Gut microbiota and healthInflammatory Bowel Disease

Cited by 164

Interplay between diet and gut microbiome, and circulating concentrations of trimethylamine N-oxide: findings from a longitudinal cohort of US men

Li, J., Li, Y., Ivey, K. L., Wang, D. D., Wilkinson, J. E., Franke, A., Lee, K. H., Chan, A., Huttenhower, C., Hu, F. B., et al. (2022) · Gut

Gut microbiota and healthNutritional Studies and Diet

Cited by 137

The human gut microbiota in people with amyotrophic lateral sclerosis

Nicholson, K., Bjornevik, K., Abu-Ali, G., Chan, J., Cortese, M., Dedi, B., Jeon, M., Xavier, R., Huttenhower, C., Ascherio, A., et al. (2021) · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 123

Analysis of 1321 Eubacterium rectale genomes from metagenomes uncovers complex phylogeographic population structure and subspecies functional adaptations

Karcher, N., Pasolli, E., Asnicar, F., Huang, K. D., Tett, A., Manara, S., Armanini, F., Bain, D., Duncan, S. H., Louis, P., et al. (2020) · Genome Biology

Gut microbiota and healthGenomics and Phylogenetic Studies

Cited by 116

Bioinformatics for the Human Microbiome Project

Gevers, D., Pop, M., Schloss, P. D., & Huttenhower, C. (2012) · PLoS Computational Biology

Genomics and Phylogenetic StudiesGut microbiota and health

Cited by 91

Metagenomics of the Gut Microbiome in Parkinson's Disease: Prodromal Changes

Palacios, N., Wilkinson, J., Bjornevik, K., Schwarzschild, M. A., McIver, L., Ascherio, A., & Huttenhower, C. (2023) · Annals of Neurology

Parkinson's Disease Mechanisms and TreatmentsGut microbiota and health

Cited by 59

GOLEM: an interactive graph-based gene-ontology navigation and analysis tool

Sealfon, R. S., Hibbs, M. A., Huttenhower, C., Myers, C. L., & Troyanskaya, O. G. (2006) · BMC Bioinformatics

Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies

Cited by 58

QseC inhibition as an antivirulence approach for colitis-associated bacteria

Rooks, M. G., Veiga, P., Reeves, A. Z., Lavoie, S., Yasuda, K., Asano, Y., Yoshihara, K., Michaud, M., Wardwell-Scott, L., Gallini, C. A., et al. (2017) · Proceedings of the National Academy of Sciences

Bacterial biofilms and quorum sensingEscherichia coli research studies

Cited by 57

Integrated molecular approaches for fermented food microbiome research

Walsh, A. M., Leech, J., Huttenhower, C., Delhomme-Nguyen, H., Crispie, F., Chervaux, C., & Cotter, P. D. (2023) · FEMS Microbiology Reviews

Probiotics and Fermented FoodsGut microbiota and health

Cited by 56

Maternal consumption of ultra-processed foods and subsequent risk of offspring overweight or obesity: Results from three prospective cohort studies

Wang, Y., Wang, K., Du, M., Khandpur, N., Rossato, S. L., Lo, C.-H., VanEvery, H., Kim, D. Y., Zhang, F. F., Chavarro, J. E., et al. (2022) · BMJ

Obesity, Physical Activity, DietConsumer Attitudes and Food Labeling

Cited by 55

Association of midlife antibiotic use with subsequent cognitive function in women

Mehta, R. S., Lochhead, P., Wang, Y., Ma, W., Nguyen, L. H., Kochar, B., Huttenhower, C., Grodstein, F., & Chan, A. T. (2022) · PLoS ONE

Dementia and Cognitive Impairment ResearchAntibiotic Use and Resistance

Cited by 26