Variation in Microbiome LPS Immunogenicity Contributes to Autoimmunity in Humans
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LPS toxicity varies depending on lipid A composition, and this depends on bacterial species, strain and environmental conditions.
“LPS toxicity varies depending on lipid A composition, and this depends on bacterial species, strain and environmental conditions [3–5].”
From The endotoxin hypothesis of neurodegeneration (2019) · cites this paper as [5]
E. coli LPS induces a strong inflammatory response via MD2/TLR4, whereas B. dorei LPS does not, and B. dorei LPS can inhibit the inflammatory response to E. coli LPS.
“E. coli LPS induces a strong inflammatory response via MD2/TLR4, whereas B. dorei LPS does not [5]. Moreover, because B. dorei LPS binds but does not activate the MD2/TLR4 receptor complex, it can inhibit the inflammatory response to E. coli LPS [5].”
From The endotoxin hypothesis of neurodegeneration (2019) · cites this paper as [5]
Some LPS species are MD2/TLR4 antagonists and anti-inflammatory as a result of binding but not activating MD2 and/or TLR4.
“Thus, some LPS species are MD2/TLR4 antagonists, and hence anti-inflammatory, as a result of binding but not activating MD2 and/or TLR4 [5].”
From The endotoxin hypothesis of neurodegeneration (2019) · cites this paper as [5]
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Ferretti, P., Pasolli, E., Tett, A., Asnicar, F., Gorfer, V., Fedi, S., Armanini, F., Truong, D. T., Manara, S., Zolfo, M., et al. (2018) · Cell Host & Microbe · doi:10.1016/j.chom.2018.06.005 · Cited by 1,292 · see citing works
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Shao, Y., Forster, S. C., Tsaliki, E., Vervier, K., Strang, A., Simpson, N., Kumar, N., Stares, M. D., Rodger, A., Brocklehurst, P., et al. (2019) · Nature · doi:10.1038/s41586-019-1560-1 · Cited by 1,088 · see citing works
Stereotypic Immune System Development in Newborn Children
Olin, A., Henckel, E., Chen, Y., Lakshmikanth, T., Pou, C., Mikeš, J., Gustafsson, A., Bernhardsson, A. K., Zhang, C., Bohlin, K., et al. (2018) · Cell · doi:10.1016/j.cell.2018.06.045 · Cited by 700 · see citing works
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Theofilopoulos, A. N., Kono, D. H., & Baccala, R. (2017) · Nature Immunology · doi:10.1038/ni.3731 · Cited by 590 · see citing works
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Drokhlyansky, E., Smillie, C. S., Wittenberghe, N. V., Ericsson, M., Griffin, G. K., Eraslan, G., Dionne, D. A., Cuoco, M. S., Goder-Reiser, M. N., Sharova, T. Y., et al. (2020) · Cell · doi:10.1016/j.cell.2020.08.003 · Cited by 585 · see citing works
Self-citationPushing the envelope: LPS modifications and their consequences
Simpson, B. W., & Trent, M. S. (2019) · Nature Reviews Microbiology · doi:10.1038/s41579-019-0201-x · Cited by 503 · see citing works
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Ilonen, J., Lempainen, J., & Veijola, R. (2019) · Nature Reviews Endocrinology · doi:10.1038/s41574-019-0254-y · Cited by 497 · see citing works
Self-citationTett, A., Huang, K. D., Asnicar, F., Fehlner-Peach, H., Pasolli, E., Karcher, N., Armanini, F., Manghi, P., Bonham, K., Zolfo, M., et al. (2019) · Cell Host & Microbe · doi:10.1016/j.chom.2019.08.018 · Cited by 476 · see citing works
Self-citationThe endotoxin hypothesis of neurodegeneration
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Kim, C. H. (2023) · Cellular & Molecular Immunology · doi:10.1038/s41423-023-00987-1 · Cited by 420 · see citing works
Flandroy, L., Poutahidis, T., Berg, G., Clarke, G. A., Dao, M. C., Decaestecker, E., Furman, E., Haahtela, T., Massart, S., Plovier, H., et al. (2018) · The Science of The Total Environment · doi:10.1016/j.scitotenv.2018.01.288 · Cited by 399 · see citing works
Probiotics, prebiotics and amelioration of diseases
Tsai, Y.-L., Lin, T.-L., Chang, C.-J., Wu, T.-R., Lai, W.-F., Lu, C.-C., & Lai, H.-C. (2019) · Journal of Biomedical Science · doi:10.1186/s12929-018-0493-6 · Cited by 388 · see citing works
Thomas, S., Izard, J., Walsh, E. K., Batich, K. A., Chongsathidkiet, P., Clarke, G. A., Sela, D. A., Muller, A. J., Mullin, J. M., Albert, K., et al. (2017) · Cancer Research · doi:10.1158/0008-5472.can-16-2929 · Cited by 369 · see citing works
Large-scale genome-wide analysis links lactic acid bacteria from food with the gut microbiome
Pasolli, E., De Filippis, F., Mauriello, I. E., Cumbo, F., Walsh, A. M., Leech, J., Cotter, P. D., Segata, N., & Ercolini, D. (2020) · Nature Communications · doi:10.1038/s41467-020-16438-8 · Cited by 367 · see citing works
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Seeley, J. J., & Ghosh, S. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.3mr0316-118rr · Cited by 366 · see citing works
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Munford, R. S. (2016) · Journal of Leukocyte Biology · doi:10.1189/jlb.3ru0316-151r · Cited by 219 · see citing works
Zhou, S.-Y., Gillilland, M. G., Wu, X., Leelasinjaroen, P., Zhang, G., Zhou, H. R., Ye, B., Lu, Y., & Owyang, C. (2017) · Journal of Clinical Investigation · doi:10.1172/jci92390 · Cited by 204 · see citing works
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Laforest‐Lapointe, I., & Arrieta, M. (2017) · Frontiers in Immunology · doi:10.3389/fimmu.2017.00788 · Cited by 185 · see citing works
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Stearns, J. C., Simioni, J. C., Gunn, E., McDonald, H., Holloway, A. C., Thabane, L., Mousseau, A., Schertzer, J. D., Ratcliffe, E. M., Rossi, L., et al. (2017) · Scientific Reports · doi:10.1038/s41598-017-16606-9 · Cited by 141 · see citing works
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Hornef, M. W., & Torow, N. (2019) · Immunology · doi:10.1111/imm.13149 · Cited by 135 · see citing works
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Yan, Q., Li, S., Yan, Q., Huo, X., Wang, C., Wang, X., Sun, Y., Zhao, W., Yu, Z., Zhang, Y., et al. (2024) · Cell · doi:10.1016/j.cell.2024.04.043 · Cited by 121 · see citing works
Suárez, L. J., Garzon, H. S., Arboleda, S., & Rodríguez, A. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2020.591255 · Cited by 122 · see citing works
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Henrick, B. M., Chew, S., Casaburi, G., Brown, H. K., Frese, S. A., Zhou, Y., Underwood, M. A., & Smilowitz, J. T. (2019) · Pediatric Research · doi:10.1038/s41390-019-0533-2 · Cited by 117 · see citing works
Gill, T., Asquith, M. J., Brooks, S. R., Rosenbaum, J. T., & Colbert, R. A. (2017) · Arthritis & Rheumatology · doi:10.1002/art.40405 · Cited by 113 · see citing works
Jian, C., Carpén, N., Helve, O., de Vos, W. M., Korpela, K., & Salonen, A. (2021) · EBioMedicine · doi:10.1016/j.ebiom.2021.103475 · Cited by 105 · see citing works
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Pfefferle, P. I., Keber, C. U., Cohen, R. M., & Garn, H. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.635935 · Cited by 103 · see citing works
Salli, K. M., Anglenius, H., Hirvonen, J., Hibberd, A. A., Ahonen, I., Saarinen, M., Tiihonen, K., Maukonen, J., & Ouwehand, A. C. (2019) · Scientific Reports · doi:10.1038/s41598-019-49497-z · Cited by 100 · see citing works
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Amenyogbe, N., Kollmann, T. R., & Ben-Othman, R. (2017) · Frontiers in Pediatrics · doi:10.3389/fped.2017.00111 · Cited by 97 · see citing works
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Steimle, A., Michaelis, L., Lorenzo, F. D., Kliem, T., Münzner, T., Maerz, J. K., Schäfer, A., Lange, A., Parusel, R., Gronbach, K., et al. (2019) · Molecular Therapy · doi:10.1016/j.ymthe.2019.07.007 · Cited by 97 · see citing works
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Girdhar, K., Huang, Q., Chow, I., Vatanen, T., Brady, C., Raisingani, A., Autissier, P., Atkinson, M. A., Kwok, W. W., Kahn, C. R., et al. (2022) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2120028119 · Cited by 100 · see citing works
Self-citationGut microbiome-mediated metabolism effects on immunity in rural and urban African populations
Stražar, M., Temba, G. S., Vlamakis, H., Kullaya, V. I., Lyamuya, F., Mmbaga, B. T., Joosten, L. A. B., van der Ven, A. J. A. M., Netea, M. G., de Mast, Q., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-25213-2 · Cited by 91 · see citing works
Self-citationMandelbaum, N., Zhang, L., Carasso, S., Ziv, T., Lifshiz‐Simon, S., Davidovich, I., Luz, I., Berinstein, E. M., Gefen, T., Cooks, T., et al. (2023) · npj Biofilms and Microbiomes · doi:10.1038/s41522-023-00400-9 · Cited by 90 · see citing works
Kuric, E., Seiron, P., Krogvold, L., Edwin, B., Buanes, T., Hanssen, K. F., Skog, O., Dahl-Jørgensen, K., & Korsgren, O. (2017) · The American Journal of Pathology · doi:10.1016/j.ajpath.2016.11.002 · Cited by 80 · see citing works
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Sterlin, D., Fadlallah, J., Slack, E. M. C., & Gorochov, G. (2019) · Mucosal Immunology · doi:10.1038/s41385-019-0192-y · Cited by 76 · see citing works
Xie, Y., Sun, J., Wei, L., Jiang, H., Hu, C., Yang, J., Huang, Y., Ruan, B., & Zhu, B. (2021) · BMC Microbiology · doi:10.1186/s12866-020-02074-1 · Cited by 75 · see citing works
Biscarini, F., Masetti, G., Muller, I., Verhasselt, H. L., Covelli, D., Colucci, G., Zhang, L., Draman, M. S., Okosieme, O. E., Taylor, P. N., et al. (2023) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/clinem/dgad030 · Cited by 75 · see citing works
LPS inactivation by a host lipase allows lung epithelial cell sensitization for allergic asthma
Qian, G., Jiang, W., Zou, B., Feng, J., Cheng, X., Gu, J., Chu, T., Niu, C., He, R., Chu, Y., et al. (2018) · The Journal of Experimental Medicine · doi:10.1084/jem.20172225 · Cited by 75 · see citing works
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Rodríguez, C. L., Shah, S. A., Rasmussen, M. A., Thorsen, J., Boulund, U., Pedersen, C. T., Castro-Mejía, J. L., Poulsen, C. E., Poulsen, C. S., Deng, L., et al. (2023) · Nature Medicine · doi:10.1038/s41591-023-02685-x · Cited by 72 · see citing works
Bai, L., Zhou, P., Li, D., & Ju, X. (2017) · Journal of Medical Microbiology · doi:10.1099/jmm.0.000568 · Cited by 72 · see citing works
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Rong, B., Tianyu, X., Tiantian, Z., Feng, R., Huang, H., Wu, Q., & Sun, C. (2018) · The Journal of Nutritional Biochemistry · doi:10.1016/j.jnutbio.2018.10.020 · Cited by 72 · see citing works
Defois, C., Ratel, J., Denis, S., Batut, B., Beugnot, R., Peyretaillade, É., Engel, E., & Peyret, P. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01562 · Cited by 70 · see citing works
Parlato, M., Charbit‐Henrion, F., Pan, J., Romano, C., Duclaux‐Loras, R., Du, M. L., Warner, N. E., Francalanci, P., Bruneau, J., Bras, M., et al. (2018) · EMBO Molecular Medicine · doi:10.15252/emmm.201708483 · Cited by 69 · see citing works
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Wasko, N. J., Nichols, F. C., & Clark, R. B. (2019) · Autoimmunity Reviews · doi:10.1016/j.autrev.2019.102430 · Cited by 63 · see citing works
The relationship between the gut microbiota and thyroid disorders
Ludgate, M. E., Masetti, G., & Soares, P. (2024) · Nature Reviews Endocrinology · doi:10.1038/s41574-024-01003-w · Cited by 64 · see citing works
Oduaran, O. H., Tamburini, F. B., Sahibdeen, V., Brewster, R., Gómez-Olivé, F. X., Kahn, K., Norris, S. A., Tollman, S. M., Twine, R., Wade, A. N., et al. (2020) · BMC Microbiology · doi:10.1186/s12866-020-02017-w · Cited by 64 · see citing works
Vargas-Caraveo, A., Sayd, A., Robledo‐Montaña, J., Caso, J. R., Madrigal, J. L. M., García‐Bueno, B., & Leza, J. C. (2020) · Journal of Neuroinflammation · doi:10.1186/s12974-019-1690-2 · Cited by 58 · see citing works
Differential Establishment of Bifidobacteria in the Breastfed Infant Gut
Lewis, Z. T., & Mills, D. A. (2017) · Nestlé Nutrition Institute Workshop series · doi:10.1159/000455399 · Cited by 56 · see citing works
Torow, N., Li, R., Hitch, T. C. A., Mingels, C., Bounny, S. A., van Best, N., Stange, E.-L., Simons, B., Maié, T., Rüttger, L., et al. (2023) · Immunity · doi:10.1016/j.immuni.2023.04.002 · Cited by 55 · see citing works
Gut microbiota in regulatory T cell generation and function: mechanisms and health implications
Sharma, A., Sharma, G., & Im, S. (2025) · Gut Microbes · doi:10.1080/19490976.2025.2516702 · Cited by 65 · see citing works
Exploring the microbiome in health and disease
Scotti, E., Boué, S., Sasso, G. L., Zanetti, F., Belcastro, V., Poussin, C., Sierro, N., Battey, J. N. D., Gimalac, A., Ivanov, N. V., et al. (2017) · Toxicology Research and Application · doi:10.1177/2397847317741884 · Cited by 55 · see citing works
Guido, G., Ausenda, G., Iascone, V., & Chisari, E. (2021) · Annals of Medicine · doi:10.1080/07853890.2021.2014557 · Cited by 56 · see citing works
Sepp, E., Smidt, I., Rööp, T., Štšepetova, J., Kõljalg, S., Mikelsaar, M., Soidla, I., Ainsaar, M., Kolk, H., Vallas, M., et al. (2022) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2022.851404 · Cited by 56 · see citing works
Gut microbiota in children and altered profiles in juvenile idiopathic arthritis
Filippo, C. D., Paola, M. D., Giani, T., Tirelli, F., & Cimaz, R. (2019) · Journal of Autoimmunity · doi:10.1016/j.jaut.2019.01.001 · Cited by 55 · see citing works
Metabolic pressure and the breach of immunological self-tolerance
Rosa, V. D., Cava, A. L., & Matarese, G. (2017) · Nature Immunology · doi:10.1038/ni.3851 · Cited by 53 · see citing works
Hygiene Hypothesis in Asthma Development: Is Hygiene to Blame?
Bernardes, E. V. T., & Arrieta, M. (2017) · Archives of Medical Research · doi:10.1016/j.arcmed.2017.11.009 · Cited by 54 · see citing works
Increased mucosal neutrophil survival is associated with altered microbiota in HIV infection
Hensley‐McBain, T., Wu, M. C., Manuzak, J. A., Cheu, R. K., Gustin, A. T., Driscoll, C. B., Zevin, A. S., Miller, C. J., Coronado, E., Smith, E. A., et al. (2019) · PLoS Pathogens · doi:10.1371/journal.ppat.1007672 · Cited by 53 · see citing works
Docimo, G., Cangiano, A., Romano, R. M., Pignatelli, M. F., Offi, C., Paglionico, V. A., Galdiero, M., Donnarumma, G., Nigro, V., Espósito, D., et al. (2020) · Frontiers in Endocrinology · doi:10.3389/fendo.2020.586529 · Cited by 52 · see citing works
A roadmap of the generation of neoantigens as targets of the immune system in type 1 diabetes
Roep, B. O., Kracht, M. J. L., van Lummel, M., & Zaldumbide, A. (2016) · Current Opinion in Immunology · doi:10.1016/j.coi.2016.09.007 · Cited by 49 · see citing works
The microbiome and immunodeficiencies: Lessons from rare diseases
Pellicciotta, M., Rigoni, R., Falcone, E. L., Holland, S. M., VILLA, A. M., & Cassani, B. (2019) · Journal of Autoimmunity · doi:10.1016/j.jaut.2019.01.008 · Cited by 52 · see citing works
Gut microbiome development in early childhood is affected by day care attendance
Amir, A., Erez‐Granat, O., Braun, T., Sosnovski, K. E., Hadar, R., BenShoshan, M., Heiman, S., Abbas‐Egbariya, H., Saar, E. G., Efroni, G., et al. (2022) · npj Biofilms and Microbiomes · doi:10.1038/s41522-021-00265-w · Cited by 47 · see citing works
Alterations of Gut Microbiome in Tibetan Patients With Coronary Heart Disease
Liu, F., Fan, C., Zhang, L., Li, Y., Hou, H., Ma, Y., Fan, J., Tan, Y., Wu, T., Jia, S., et al. (2020) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2020.00373 · Cited by 50 · see citing works
High-resolution strain-level microbiome composition analysis from short reads
Liao, H., Ji, Y., & Sun, Y. (2023) · Microbiome · doi:10.1186/s40168-023-01615-w · Cited by 50 · see citing works
Gill, T., Brooks, S. R., Rosenbaum, J. T., Asquith, M. J., & Colbert, R. A. (2019) · Arthritis & Rheumatology · doi:10.1002/art.41018 · Cited by 48 · see citing works
Chattopadhyay, I., & Shankar, E. M. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.590874 · Cited by 46 · see citing works
Li, W., Li, L., Yang, F., Hu, Q., & Xiong, D. (2022) · Annals of Translational Medicine · doi:10.21037/atm-22-3967 · Cited by 47 · see citing works
Maerz, J. K., Trostel, C., Lange, A., Parusel, R., Michaelis, L., Schäfer, A., Yao, H., Löw, H.-C., & Frick, J.-S. (2020) · Frontiers in Immunology · doi:10.3389/fimmu.2019.03093 · Cited by 44 · see citing works
Lian, N., Shen, M., Zhang, K., Pan, J., Jiang, Y., Yu, Y., & Yu, Y. (2021) · Journal of Pain Research · doi:10.2147/jpr.s288289 · Cited by 44 · see citing works
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Zhang, K., Paul, K. C., Jacobs, J. P., Chou, H. L., Folle, A. D., Rosario, I. D., Yu, Y., Bronstein, J. M., Keener, A. M., & Ritz, B. R. (2022) · Journal of Parkinson s Disease · doi:10.3233/jpd-223500 · Cited by 43 · see citing works
Global phylogeography and ancient evolution of the widespread human gut virus crAssphagePreprint
Edwards, R. A., Vega, A. A., Norman, H., Ohaeri, M. C., Levi, K., Dinsdale, E. A., Cinek, O., Aziz, R. K., McNair, K. A., Barr, J. J., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/527796 · Cited by 43 · see citing works
Zhang, X., & Yi, N. (2020) · Bioinformatics · doi:10.1093/bioinformatics/btz973 · Cited by 42 · see citing works
Gut microbiome dysbiosis in inflammatory bowel disease
Lal, S., Kandiyal, B., Ahuja, V., Takeda, K., & Das, B. (2022) · Progress in molecular biology and translational science · doi:10.1016/bs.pmbts.2022.09.003 · Cited by 43 · see citing works
Effects of gut-derived endotoxin on anxiety-like and repetitive behaviors in male and female mice
Fields, C. T., Chassaing, B., Castillo‐Ruiz, A., Osan, R. M., Gewirtz, A. T., & Vries, G. J. D. (2018) · Biology of Sex Differences · doi:10.1186/s13293-018-0166-x · Cited by 40 · see citing works
Permissive microbiome characterizes human subjects with a neurovascular disease cavernous angioma
Polster, S. P., Sharma, A., Tanes, C., Tang, A. T., Mericko, P. A., Cao, Y. J., Carrión‐Penagos, J., Girard, R., Koskimäki, J., Zhang, D., et al. (2020) · Nature Communications · doi:10.1038/s41467-020-16436-w · Cited by 40 · see citing works
Pither, M. D., Illiano, A., Pagliuca, C., Jacobson, A. N., Mantova, G., Stornaiuolo, A., Colicchio, R., Vitiello, M., Pinto, G., Silipo, A., et al. (2022) · Carbohydrate Polymers · doi:10.1016/j.carbpol.2022.120040 · Cited by 39 · see citing works
Obesity and asthma: risk, control and treatment
Marko, M., & Pawliczak, R. (2018) · Advances in Dermatology and Allergology · doi:10.5114/ada.2018.77607 · Cited by 37 · see citing works
Fluoride Depletes Acidogenic Taxa in Oral but Not Gut Microbial Communities in Mice
Yasuda, K., Hsu, T. Y., Gallini, C. A., Mclver, L. J., Schwager, E., Shi, A., DuLong, C. R., Schwager, R., Abu-Ali, G., Franzosa, E. A., et al. (2017) · mSystems · doi:10.1128/msystems.00047-17 · Cited by 36 · see citing works
Self-citationMunford, R. S., Weiss, J. P., & Lu, M. (2020) · Journal of Biological Chemistry · doi:10.1074/jbc.rev120.015254 · Cited by 36 · see citing works
Pan, Z., Wu, N., & Jin, C. (2023) · Canadian Journal of Infectious Diseases and Medical Microbiology · doi:10.1155/2023/3080969 · Cited by 34 · see citing works
He, L. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22042121 · Cited by 34 · see citing works
Harvey, D. J. (2021) · Mass Spectrometry Reviews · doi:10.1002/mas.21651 · Cited by 33 · see citing works
From Disease and Patient Heterogeneity to Precision Medicine in Type 1 Diabetes
den Hollander, N. H. M., & Roep, B. O. (2022) · Frontiers in Medicine · doi:10.3389/fmed.2022.932086 · Cited by 32 · see citing works
Targeting innate immunity to downmodulate adaptive immunity and reverse type 1 diabetes
Itoh, A., & Ridgway, W. M. (2017) · ImmunoTargets and Therapy · doi:10.2147/itt.s117264 · Cited by 32 · see citing works
Experimental Models of Autoimmune Demyelinating Diseases in Nonhuman Primates
Stimmer, L., Fovet, C.-M., & Serguera, C. (2017) · Veterinary Pathology · doi:10.1177/0300985817712794 · Cited by 32 · see citing works
- Authors
- Vatanen, T., Kostic, A. D., d’Hennezel, E., Siljander, H., Franzosa, E. A., Yassour, M., Kolde, R., Vlamakis, H., Arthur, T. D., Hämäläinen, A.-M., Peet, A., Tillmann, V., Uibo, R., Mokurov, S., Dorshakova, N., Ilonen, J., Virtanen, S. M., Szabo, S. J., Porter, J. A., Lähdesmäki, H., Huttenhower, C., Gevers, D., Cullen, T. W., Knip, M., & Xavier, R. J.
- Corresponding author
- Xavier, Ramnik J.
- ORCID
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2016-06
- Volume
- 165
- Issue
- 6
- Pages
- 1551
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W4239130026
- Cited by
- 298
- References
- 0
- Citations by year
- 2026: 11 · 2025: 18 · 2024: 22 · 2023: 35 · 2022: 45 · 2021: 41 · 2020: 29 · 2019: 42 · 2018: 20 · 2017: 30 · 2016: 5
- FWCI
- 13.81
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- Locations
- Cell (publishedVersion)
- Funders
- Novo Nordisk Fonden (NNF11OC1014751)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
- Life Sciences › Immunology and Microbiology › Immunology › Immune Response and Inflammation
- Life Sciences › Immunology and Microbiology › Immunology › T-cell and B-cell Immunology
- Keywords
- gut microbiota, lipopolysaccharide, immunogenicity, autoimmunity, type 1 diabetes, Bacteroides, immune tolerance, children
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
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