Shuldiner, Alan R.

Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile

Kilpeläinen, T. O., Zillikens, M. C., Stančákova, A., Finucane, F. M., Ried, J. S., Langenberg, C., Zhang, W., Beckmann, J. S., Luan, J., Vandenput, L., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 335

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Common and rare variant associations with clonal haematopoiesis phenotypes

Kessler, M. D., Damask, A., O’Keeffe, S., Banerjee, N., Li, D., Watanabe, K., Marketta, A., Van Meter, M., Semrau, S., Horowitz, J., et al. (2022) · Nature

Acute Myeloid Leukemia ResearchGenetic Associations and Epidemiology

Cited by 313

Physical Activity and the Association of Common FTO Gene Variants With Body Mass Index and Obesity

Rampersaud, E., Mitchell, B. D., Pollin, T. I., Fu, M., Shen, H., O’Connell, J. R., Ducharme, J. L., Hines, S., Sack, P., Naglieri, R., et al. (2008) · Archives of Internal Medicine

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 299

Whole-genome association study identifies STK39 as a hypertension susceptibility gene

Wang, Y., O'Connell, J. R., McArdle, P. F., Wade, J. B., Dorff, S. E., Shah, S. J., Shi, X., Pan, L., Rampersaud, E., Shen, H., et al. (2009) · Proceedings of the National Academy of Sciences

Blood Pressure and Hypertension StudiesGenetic Associations and Epidemiology

Cited by 298

Meta-analysis of genome-wide association data identifies two loci influencing age at menarche

Perry, J. R. B., Stolk, L., Franceschini, N., Lunetta, K. L., Zhai, G., McArdle, P. F., Smith, A. V., Aspelund, T., Bandinelli, S., Boerwinkle, E., et al. (2009) · Nature Genetics

Hypothalamic control of reproductive hormonesGenetic Associations and Epidemiology

Cited by 294

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

Akbari, P., Gilani, A., Sosina, O., Kosmicki, J. A., Khrimian, L., Fang, Y.-Y., Persaud, T., Garcia, V., Sun, D., Li, A., et al. (2021) · Science

Genetic Associations and EpidemiologyRegulation of Appetite and Obesity

Cited by 276

Common variants in 40 genes assessed for diabetes incidence and response to metformin and lifestyle intervention in the Diabetes Prevention Program

Jablonski, K. A., McAteer, J. B., de Bakker, P. I. W., Franks, P. W., Pollin, T. I., Hanson, R. L., Saxena, R., Fowler, S., Shuldiner, A. R., Knowler, W. C., et al. (2010) · Diabetes

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 271

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

the CARDIoGRAM Consortium, Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyCardiovascular Health and Disease Prevention

Cited by 212

Association Between a Novel Variant of the Human Type 2 Deiodinase Gene Thr92Ala and Insulin Resistance

Mentuccia, D., Proietti-Pannunzi, L., Tanner, K., Bacci, V., Pollin, T. I., Poehlman, E. T., Shuldiner, A. R., & Celi, F. S. (2002) · Diabetes

Thyroid Disorders and TreatmentsGenetic Associations and Epidemiology

Cited by 205

An international genome-wide meta-analysis of primary biliary cholangitis: Novel risk loci and candidate drugs

Cordell, H. J., Fryett, J. J., Ueno, K., Darlay, R., Aiba, Y., Hitomi, Y., Kawashima, M., Nishida, N., Khor, S.-S., Gervais, O., et al. (2021) · Journal of Hepatology

Liver Diseases and ImmunityGenetic Associations and Epidemiology

Cited by 182

Genome-wide association analyses highlight etiological differences underlying newly defined subtypes of diabetes

Mansour Aly, D., Dwivedi, O. P., Prasad, R. B., Käräjämäki, A., Hjort, R., Thangam, M., Åkerlund, M., Mahajan, A., Udler, M. S., Florez, J. C., et al. (2021) · Nature Genetics

Genetic Associations and EpidemiologyDiabetes and associated disorders

Cited by 172

Identification of Novel Candidate Genes for Type 2 Diabetes From a Genome-Wide Association Scan in the Old Order Amish

Rampersaud, E., Damcott, C. M., Fu, M., Shen, H., McArdle, P., Shi, X., Shelton, J., Yin, J., Chang, Y.-P. C., Ott, S. H., et al. (2007) · Diabetes

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 170

Phosphodiesterase 8B Gene Variants Are Associated with Serum TSH Levels and Thyroid Function

Arnaud-Lopez, L., Usala, G., Ceresini, G., Mitchell, B. D., Pilia, M. G., Piras, M. G., Sestu, N., Maschio, A., Busonero, F., Albai, G., et al. (2008) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyThyroid Disorders and Treatments

Cited by 139

Germline Mutations in CIDEB and Protection against Liver Disease

Verweij, N., Haas, M. E., Nielsen, J. B., Sosina, O. A., Kim, M., Akbari, P., De, T., Hindy, G., Bovijn, J., Persaud, T., et al. (2022) · New England Journal of Medicine

Liver Disease Diagnosis and TreatmentGenetic Associations and Epidemiology

Cited by 127

Genetic Predictors of Weight Loss and Weight Regain After Intensive Lifestyle Modification, Metformin Treatment, or Standard Care in the Diabetes Prevention Program

Delahanty, L. M., Pan, Q., Jablonski, K. A., Watson, K. E., McCaffery, J. M., Shuldiner, A., Kahn, S. E., Knowler, W. C., Florez, J. C., Franks, P. W., et al. (2012) · Diabetes Care

Nutrition, Genetics, and DiseaseGenetic Associations and Epidemiology

Cited by 116

Whole exome sequencing and characterization of coding variation in 49,960 individuals in the UK Biobank

Van Hout, C. V., Tachmazidou, I., Backman, J. D., Hoffman, J. X., Ye, B., Pandey, A. K., Gonzaga-Jauregui, C., Khalid, S., Liu, D., Banerjee, N., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 110

COL4A1 Is Associated With Arterial Stiffness by Genome-Wide Association Scan

Tarasov, K. V., Sanna, S., Scuteri, A., Strait, J. B., Orrù, M., Parsa, A., Lin, P.-I., Maschio, A., Lai, S., Piras, M. G., et al. (2009) · Circulation: Cardiovascular Genetics

Cardiovascular Health and Disease PreventionGenetic Associations and Epidemiology

Cited by 104

Serum 25-hydroxyvitamin D levels are not associated with subclinical vascular disease or C-reactive protein in the old order amish

Michos, E. D., Streeten, E. A., Ryan, K. A., Rampersaud, E., Peyser, P. A., Bielak, L. F., Shuldiner, A. R., Mitchell, B. D., & Post, W. (2009) · Calcified Tissue International

Vitamin D Research StudiesParathyroid Disorders and Treatments

Cited by 77

The impact of physical activity on the prevention of type 2 diabetes: Evidence and lessons learned from the Diabetes Prevention Program, a long-standing clinical trial incorporating subjective and objective activity measures

Kriska, A. M., Rockette-Wagner, B., Edelstein, S. L., Bray, G. A., Delahanty, L. M., Hoskin, M. A., Horton, E. S., Venditti, E. M., Knowler, W. C., DPP Research Group, et al. (2021) · Diabetes Care

Physical Activity and HealthDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 70

The genetics of obesity

Damcott, C. M., Sack, P., & Shuldiner, A. R. (2003) · Endocrinology and Metabolism Clinics of North America

Genetic Associations and EpidemiologyNutrition, Genetics, and Disease

Cited by 63

Habitual sleep/wake patterns in the Old Order Amish: heritability and association with non-genetic factors

Evans, D. S., Snitker, S., Wu, S.-H., Mody, A., Njajou, O. T., Perlis, M. L., Gehrman, P. R., Shuldiner, A. R., & Hsueh, W.-C. (2011) · SLEEP

Sleep and related disordersCircadian rhythm and melatonin

Cited by 53

The ABCG8 G574R Variant, Serum Plant Sterol Levels, and Cardiovascular Disease Risk in the Old Order Amish

Horenstein, R. B., Mitchell, B. D., Post, W. S., Lütjohann, D., von Bergmann, K., Ryan, K. A., Terrin, M., Shuldiner, A. R., & Steinle, N. I. (2013) · Arteriosclerosis Thrombosis and Vascular Biology

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 36

The Diabetes Prevention Program and Its Outcomes Study: NIDDK’s Journey Into the Prevention of Type 2 Diabetes and Its Public Health Impact

Crandall, J. P., Dabelea, D., Knowler, W. C., Nathan, D. M., Temprosa, M., DPP Research Group, Bray, G. A., Gadde, K. M., Culbert, I. W., Arceneaux, J., et al. (2025) · Diabetes Care

Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Treatment and Management

Cited by 29