Finkel, Toren

Mitohormesis

Yun, J., & Finkel, T. (2014) · Cell Metabolism

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 626

The Mammalian Target of Rapamycin (mTOR) Pathway Regulates Mitochondrial Oxygen Consumption and Oxidative Capacity

Schieke, S. M., Phillips, D., McCoy, J. P., Aponte, A. M., Shen, R.-F., Balaban, R. S., & Finkel, T. (2006) · Journal of Biological Chemistry

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 623

T cell stemness and dysfunction in tumors are triggered by a common mechanism

Vodnala, S. K., Eil, R., Kishton, R. J., Sukumar, M., Yamamoto, T. N., Ha, N.-H., Lee, P.-H., Shin, M., Patel, S. J., Yu, Z., et al. (2019) · Science

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 552

Bmi1 regulates mitochondrial function and the DNA damage response pathway

Liu, J., Cao, L., Chen, J., Song, S., Lee, I. H., Quijano, C., Liu, H., Keyvanfar, K., Chen, H., Cao, L.-Y., et al. (2009) · Nature

Epigenetics and DNA MethylationMitochondrial Function and Pathology

Cited by 474

Role for mitochondrial oxidants as regulators of cellular metabolism

Nemoto, S., Takeda, K., Yu, Z.-X., Ferrans, V. J., & Finkel, T. (2000) · Molecular and Cellular Biology

Mitochondrial Function and PathologyRedox biology and oxidative stress

Cited by 393

Signal Transduction by Mitochondrial Oxidants

Finkel, T. (2012) · Journal of Biological Chemistry

Redox biology and oxidative stressMitochondrial Function and Pathology

Cited by 390

The role of mitochondria in aging

Jang, J. Y., Blum, A., Liu, J., & Finkel, T. (2018) · Journal of Clinical Investigation

Mitochondrial Function and PathologyGenetics, Aging, and Longevity in Model Organisms

Cited by 358

Free radicals and senescence

Lu, T., & Finkel, T. (2008) · Experimental Cell Research

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 327

The metabolic regulation of aging

Finkel, T. (2015) · Nature Medicine

Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine

Cited by 325

Reactive Oxygen Species as Mediators of Cellular Senescence

Colavitti, R., & Finkel, T. (2005) · IUBMB Life

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 242

The impact of aging on cardiac extracellular matrix

Meschiari, C. A., Ero, O. K., Pan, H., Finkel, T., & Lindsey, M. L. (2017) · GeroScience

Cardiac Fibrosis and RemodelingProtease and Inhibitor Mechanisms

Cited by 237

Radical medicine: treating ageing to cure disease

Finkel, T. (2005) · Nature Reviews Molecular Cell Biology

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 234

Vascular Effects Following Homozygous Disruption of p47 phox: An Essential Component of NADPH Oxidase

Hsich, E., Segal, B. H., Pagano, P. J., Rey, F. E., Paigen, B., Deleonardis, J., Hoyt, R. F., Holland, S. M., & Finkel, T. (2000) · Circulation

Nitric Oxide and Endothelin EffectsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 158

Oncogene-induced senescence results in marked metabolic and bioenergetic alterations

Quijano, C., Cao, L., Fergusson, M. M., Romero, H., Liu, J., Gutkind, S., Rovira, I. I., Mohney, R. P., Karoly, E. D., & Finkel, T. (2012) · Cell Cycle

Telomeres, Telomerase, and SenescenceCancer, Lipids, and Metabolism

Cited by 155

NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health.

SenNet Consortium, Writing Group, Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., et al. (2022) · Nature Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 122

Mitochondrial signaling, TOR, and life span

Schieke, S. M., & Finkel, T. (2006) · Biological Chemistry

Genetics, Aging, and Longevity in Model OrganismsMitochondrial Function and Pathology

Cited by 106

Xanthine Oxidoreductase Is an Endogenous Regulator of Cyclooxygenase-2

Ohtsubo, T., Rovira, I. I., Starost, M. F., Liu, C., & Finkel, T. (2004) · Circulation Research

Gout, Hyperuricemia, Uric AcidInflammatory mediators and NSAID effects

Cited by 99

Cardiovascular disease and the biology of aging

Moturi, S., Ghosh-Choudhary, S. K., & Finkel, T. (2022) · Journal of Molecular and Cellular Cardiology

Telomeres, Telomerase, and SenescenceCardiovascular Health and Disease Prevention

Cited by 56

Transcriptional and proteomic characterization of telomere-induced senescence in a human alveolar epithelial cell line

Sullivan, D. I., Jiang, M., Hinchie, A. M., Roth, M. G., Bahudhanapati, H., Nouraie, M., Liu, J., McDyer, J. F., Mallampalli, R. K., Zhang, Y., et al. (2021) · Frontiers in Medicine

Telomeres, Telomerase, and SenescenceInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Cited by 16

Senolytic vaccination: a new mandate for cardiovascular health?

Lear, T. B., & Finkel, T. (2022) · The Journal of Cardiovascular Aging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 8