Sofroniew, Michael V.

Astrocytes: Biology and pathology

Sofroniew, M. V., & Vinters, H. V. (2010) · Acta Neuropathologica

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 5,196

Molecular dissection of reactive astrogliosis and glial scar formation

Sofroniew, M. V. (2009) · Trends in Neurosciences

Neuroinflammation and Neurodegeneration MechanismsSpinal Cord Injury Research

Cited by 2,594

Reactive astrocyte nomenclature, definitions, and future directions

Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 2,513

Astrocyte scar formation aids central nervous system axon regeneration

Anderson, M. A., Burda, J. E., Ren, Y., Ao, Y., O’Shea, T. M., Kawaguchi, R., Coppola, G., Khakh, B. S., Deming, T. J., & Sofroniew, M. V. (2016) · Nature

Nerve injury and regenerationSpinal Cord Injury Research

Cited by 1,851

Nerve Growth Factor Signaling, Neuroprotection, and Neural Repair

Sofroniew, M. V., Howe, C. L., & Mobley, W. C. (2001) · Annual Review of Neuroscience

Nerve injury and regenerationNeurogenesis and neuroplasticity mechanisms

Cited by 1,284

Diversity of astrocyte functions and phenotypes in neural circuits

Khakh, B. S., & Sofroniew, M. V. (2015) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,239

Astrocyte barriers to neurotoxic inflammation

Sofroniew, M. V. (2015) · Nature Reviews Neuroscience

Neuroinflammation and Neurodegeneration MechanismsBarrier Structure and Function Studies

Cited by 1,202

Leukocyte Infiltration, Neuronal Degeneration, and Neurite Outgrowth after Ablation of Scar-Forming, Reactive Astrocytes in Adult Transgenic Mice

Bush, T. G., Puvanachandra, N., Horner, C. H., Polito, A., Ostenfeld, T., Svendsen, C. N., Mucke, L., Johnson, M. H., & Sofroniew, M. V. (1999) · Neuron

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,116

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

Saxe, M. D., Battaglia, F., Wang, J.-W., Malleret, G., David, D. J., Monckton, J. E., Garcia, A. D. R., Sofroniew, M. V., Kandel, E. R., Santarelli, L., et al. (2006) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,020

STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

Herrmann, J. E., Imura, T., Song, B., Qi, J., Ao, Y., Nguyen, T. K., Korsak, R. A., Takeda, K., Akira, S., & Sofroniew, M. V. (2008) · The Journal of Neuroscience

Spinal Cord Injury ResearchCytokine Signaling Pathways and Interactions

Cited by 958

Glial Scar Borders Are Formed by Newly Proliferated, Elongated Astrocytes That Interact to Corral Inflammatory and Fibrotic Cells via STAT3-Dependent Mechanisms after Spinal Cord Injury

Wanner, I. B., Anderson, M. A., Song, B., Levine, J., Fernandez, A., Gray-Thompson, Z., Ao, Y., & Sofroniew, M. V. (2013) · Journal of Neuroscience

Spinal Cord Injury ResearchTraumatic Brain Injury and Neurovascular Disturbances

Cited by 839

Astrocyte-derived VEGF-A drives blood-brain barrier disruption in CNS inflammatory disease

Argaw, A. T., Asp, L., Zhang, J., Navrazhina, K., Pham, T., Mariani, J. N., Mahase, S., Dutta, D. J., Seto, J., Kramer, E. G., et al. (2012) · Journal of Clinical Investigation

Barrier Structure and Function StudiesMultiple Sclerosis Research Studies

Cited by 733

Astrocyte Reactivity: Subtypes, States, and Functions in CNS Innate Immunity

Sofroniew, M. V. (2020) · Trends in Immunology

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 721

Transformation of nonfunctional spinal circuits into functional states after the loss of brain input

Courtine, G., Gerasimenko, Y., van den Brand, R., Yew, A., Musienko, P., Zhong, H., Song, B., Ao, Y., Ichiyama, R. M., Lavrov, I., et al. (2009) · Nature Neuroscience

Spinal Cord Injury ResearchNerve injury and regeneration

Cited by 706

Astrogliosis

Sofroniew, M. V. (2015) · Cold Spring Harbor Perspectives in Biology

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 695

Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

Tong, X., Ao, Y., Faas, G. C., Nwaobi, S. E., Xu, J., Haustein, M. D., Anderson, M. A., Mody, I., Olsen, M. L., Sofroniew, M. V., et al. (2014) · Nature Neuroscience

Genetic Neurodegenerative DiseasesNeuroscience and Neuropharmacology Research

Cited by 592

Spinal cord repair: advances in biology and technology

Courtine, G., & Sofroniew, M. V. (2019) · Nature Medicine

Spinal Cord Injury ResearchNerve injury and regeneration

Cited by 508

Astrocytes in human central nervous system diseases: a frontier for new therapies

Verkhratsky, A., Butt, A., Li, B., Illes, P., Zorec, R., Semyanov, A., Tang, Y., & Sofroniew, M. V. (2023) · Signal Transduction and Targeted Therapy

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 428

Morphology of vasopressin and oxytocin neurones and their central and vascular projections

Sofroniew, M. V. (1983) · Progress in Brain Research

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 370

Multiple Roles for Astrocytes as Effectors of Cytokines and Inflammatory Mediators

Sofroniew, M. V. (2014) · The Neuroscientist

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 333

Projections from vasopressin, oxytocin, and neurophysin neurons to neural targets in the rat and human

Sofroniew, M. V. (1980) · Journal of Histochemistry & Cytochemistry

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

Cited by 317

Projections from the parvocellular vasopressin‐ and neurophysin‐containing neurons of the suprachiasmatic nucleus

Sofroniew, M. V., & Weindl, A. (1978) · American Journal of Anatomy

Circadian rhythm and melatoninNeuroendocrine regulation and behavior

Cited by 312

Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes

Itoh, N., Itoh, Y., Tassoni, A., Ren, E., Kaito, M., Ohno, A., Ao, Y., Farkhondeh, V., Johnsonbaugh, H., Burda, J., et al. (2018) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 253

Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors

Hamby, M. E., Coppola, G., Ao, Y., Geschwind, D. H., Khakh, B. S., & Sofroniew, M. V. (2012) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 228