Lau, Lester F.

Cytotoxicity of TNFα is regulated by integrin‐mediated matrix signaling

Chen, C., Young, J. L., Monzon, R. I., Chen, N., Todorović, V., & Lau, L. F. (2007) · The EMBO Journal

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 143

The matrix protein CCN1 (CYR61) induces apoptosis in fibroblasts

Todorovicç, V., Chen, C.-C., Hay, N., & Lau, L. F. (2005) · The Journal of Cell Biology

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 132

Identification of a Novel Integrin αvβ3 Binding Site in CCN1 (CYR61) Critical for Pro-angiogenic Activities in Vascular Endothelial Cells

Chen, N., Leu, S.-J., Todorović, V., Lam, S. C.-T., & Lau, L. F. (2004) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchCell Adhesion Molecules Research

Cited by 132

Identification of a novel integrin α6β1 binding site in the angiogenic Inducer CCN1 (CYR61)

Leu, S.-J., Liu, Y., Chen, N., Chen, C.-C., Lam, S. C.-T., & Lau, L. F. (2003) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchCell Adhesion Molecules Research

Cited by 131

The Matricellular Protein CCN1 Is Essential for Cardiac Development

Mo, F.-E., & Lau, L. F. (2006) · Circulation Research

Congenital heart defects researchConnective Tissue Growth Factor Research

Cited by 112

CCN1 induces hepatic ductular reaction through integrin αvβ5–mediated activation of NF-κB

Kim, K.-H., Chen, C.-C., Alpini, G., & Lau, L. F. (2015) · Journal of Clinical Investigation

Liver physiology and pathologyConnective Tissue Growth Factor Research

Cited by 109

Mechanical Regulation of the Proangiogenic Factor CCN1/CYR61 Gene Requires the Combined Activities of MRTF-A and CREB-binding Protein Histone Acetyltransferase

Hanna, M., Liu, H., Amir, J., Sun, Y., Morris, S. W., Siddiqui, M. A. Q., Lau, L. F., & Chaqour, B. (2009) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchCellular Mechanics and Interactions

Cited by 106

Senescent hepatic stellate cells promote liver regeneration through IL-6 and ligands of CXCR2

Cheng, N., Kim, K.-H., & Lau, L. F. (2022) · JCI Insight

Liver physiology and pathologyTelomeres, Telomerase, and Senescence

Cited by 87

Promoter function and structure of the growth factorinducible immediate early gene cyr 61

Latinkic, B. V., Brien, T. P. O., & Lau, L. F. (1991) · Nucleic Acids Research

Genomics and Chromatin DynamicsConnective Tissue Growth Factor Research

Cited by 87

Xenopus Cyr61 regulates gastrulation movements and modulates Wnt signalling

Latinkic, B. V., Mercurio, S., Bennett, B., Hirst, E. M. A., Xu, Q., Lau, L. F., Mohun, T. J., & Smith, J. C. (2003) · Development

Developmental Biology and Gene RegulationConnective Tissue Growth Factor Research

Cited by 77

Identification of a Novel Integrin αMβ2 Binding Site in CCN1 (CYR61), a Matricellular Protein Expressed in Healing Wounds and Atherosclerotic Lesions

Schober, J. M., Lau, L. F., Ugarova, T. P., & Lam, S. C.-T. (2003) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchCell Adhesion Molecules Research

Cited by 76

Targeted Mutagenesis of the Angiogenic Protein CCN1 (CYR61)

Leu, S.-J., Chen, N., Chen, C.-C., Todorović, V., Bai, T., Juric, V., Liu, Y., Yan, G., Lam, S. C.-T., & Lau, L. F. (2004) · Journal of Biological Chemistry

Connective Tissue Growth Factor ResearchBone and Dental Protein Studies

Cited by 72

Fas-Mediated Apoptosis Is Regulated by the Extracellular Matrix Protein CCN1 (CYR61) In Vitro and In Vivo

Juric, V., Chen, C.-C., & Lau, L. F. (2009) · Molecular and Cellular Biology

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 70

Matrix Protein CCN1 Is Critical for Prostate Carcinoma Cell Proliferation and TRAIL-Induced Apoptosis

Franzen, C. A., Chen, C.-C., Todorović, V., Juric, V., Monzon, R. I., & Lau, L. F. (2009) · Molecular Cancer Research

Connective Tissue Growth Factor ResearchBone and Dental Protein Studies

Cited by 66

Cyr61 Protects against Hyperoxia-Induced Cell Death via Akt Pathway in Pulmonary Epithelial Cells

Jin, Y., Kim, H. P., Ifedigbo, E., Lau, L. F., & Choi, A. M. K. (2005) · American Journal of Respiratory Cell and Molecular Biology

Connective Tissue Growth Factor ResearchNeonatal Respiratory Health Research

Cited by 48

Deadly liaisons: fatal attraction between CCN matricellular proteins and the tumor necrosis factor family of cytokines

Chen, C., & Lau, L. F. (2010) · Journal of Cell Communication and Signaling

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 47

Cellular communication network factor 1‐stimulated liver macrophage efferocytosis drives hepatic stellate cell activation and liver fibrosis

Kim, K., Cheng, N., & Lau, L. F. (2022) · Hepatology Communications

Liver physiology and pathologyConnective Tissue Growth Factor Research

Cited by 26

INTEGRIN-MEDIATED CCN FUNCTIONS

Lau, L. F., & Lam, S. C. T. (2005) · CCN Proteins

Connective Tissue Growth Factor ResearchCell Adhesion Molecules Research

Cited by 16

The Extracellular Matrix Protein CCN1 Dictates TNFα and FasL Cytotoxicity In Vivo

Chen, C.-C., Juric, V., & Lau, L. F. (2011) · Advances in Experimental Medicine and Biology

Connective Tissue Growth Factor ResearchCell death mechanisms and regulation

Cited by 8