Deisseroth, Karl

Next-generation probes, particles, and proteins for neural interfacing

Rivnay, J., Wang, H., Fenno, L., Deisseroth, K., & Malliaras, G. G. (2017) · Science Advances

Neuroscience and Neural EngineeringUndergraduate Neuroscience Education and Research

Cited by 514

Projections from neocortex mediate top-down control of memory retrieval

Rajasethupathy, P., Sankaran, S., Marshel, J. H., Kim, C. K., Ferenczi, E., Lee, S. Y., Berndt, A., Ramakrishnan, C., Jaffe, A., Lo, M., et al. (2015) · Nature

Memory and Neural MechanismsMemory Processes and Influences

Cited by 509

Maturation and circuit integration of transplanted human cortical organoids

Revah, O., Gore, F., Kelley, K. W., Andersen, J., Sakai, N., Chen, X., Li, M.-Y., Birey, F., Yang, X., Saw, N. L., et al. (2022) · Nature

Neurogenesis and neuroplasticity mechanismsPluripotent Stem Cells Research

Cited by 504

Repeated cortico-striatal stimulation generates persistent OCD-like behavior

Ahmari, S. E., Spellman, T., Douglass, N. L., Kheirbek, M. A., Simpson, H. B., Deisseroth, K., Gordon, J. A., & Hen, R. (2013) · Science

Obsessive-Compulsive Spectrum DisordersDeep Brain Stimulation and Movement Disorders

Cited by 502

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

Romanov, R. A., Zeisel, A., Bakker, J., Girach, F., Hellysaz, A., Tomer, R., Alpár, A., Mulder, J., Clotman, F., Keimpema, E., et al. (2017) · Nature Neuroscience

Single-cell and spatial transcriptomicsCircadian rhythm and melatonin

Cited by 502

Ventral hippocampal afferents to the nucleus accumbens regulate susceptibility to depression

Bagot, R. C., Parise, E. M., Peña, C. J., Zhang, H.-X., Maze, I., Chaudhury, D., Persaud, B., Cachope, R., Bolaños-Guzmán, C. A., Cheer, J. F., et al. (2015) · Nature Communications

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 491

Hybrid Periportal Hepatocytes Regenerate the Injured Liver without Giving Rise to Cancer

Font-Burgada, J., Shalapour, S., Ramaswamy, S., Hsueh, B., Rossell, D., Umemura, A., Taniguchi, K., Nakagawa, H., Valasek, M. A., Ye, L., et al. (2015) · Cell

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 486

Basomedial amygdala mediates top-down control of anxiety and fear

Adhikari, A., Lerner, T. N., Finkelstein, J., Pak, S., Jennings, J. H., Davidson, T. J., Ferenczi, E., Gunaydin, L. A., Mirzabekov, J. J., Ye, L., et al. (2015) · Nature

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 485

Cholinergic Interneurons Control Local Circuit Activity and Cocaine Conditioning

Witten, I. B., Lin, S.-C., Brodsky, M., Prakash, R., Diester, I., Anikeeva, P., Gradinaru, V., Ramakrishnan, C., & Deisseroth, K. (2010) · Science

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 467

Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

Marcinkiewcz, C. A., Mazzone, C. M., D’Agostino, G., Halladay, L. R., Hardaway, J. A., DiBerto, J. F., Navarro, M., Burnham, N., Cristiano, C., Dorrier, C. E., et al. (2016) · Nature

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 456

An optogenetic toolbox designed for primates

Diester, I., Kaufman, M. T., Mogri, M., Pashaie, R., Goo, W., Yizhar, O., Ramakrishnan, C., Deisseroth, K., & Shenoy, K. V. (2011) · Nature Neuroscience

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 443

Mapping projections of molecularly defined dopamine neuron subtypes using intersectional genetic approaches

Poulin, J.-F., Caronia, G., Hofer, C., Cui, Q., Helm, B., Ramakrishnan, C., Chan, C. S., Dombeck, D. A., Deisseroth, K., & Awatramani, R. (2018) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 423

High-speed imaging reveals neurophysiological links to behavior in an animal model of depression

Airan, R. D., Meltzer, L. A., Roy, M., Gong, Y., Chen, H., & Deisseroth, K. (2007) · Science

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 396

Thirst-associated preoptic neurons encode an aversive motivational drive.

Allen, W. E., DeNardo, L. A., Chen, M. Z., Liu, C. D., Loh, K. M., Fenno, L. E., Ramakrishnan, C., Deisseroth, K., & Luo, L. (2017) · Science

Regulation of Appetite and ObesityNeurotransmitter Receptor Influence on Behavior

Cited by 390

A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward

Stamatakis, A. M., Jennings, J. H., Ung, R. L., Blair, G. A., Weinberg, R. J., Neve, R. L., Boyce, F., Mattis, J., Ramakrishnan, C., Deisseroth, K., et al. (2013) · Neuron

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 364

Dopaminergic dynamics underlying sex-specific cocaine reward

Calipari, E. S., Juarez, B., Morel, C., Walker, D. M., Cahill, M. E., Ribeiro, E., Roman-Ortiz, C., Ramakrishnan, C., Deisseroth, K., Han, M.-H., et al. (2017) · Nature Communications

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 359

Optogenetic interrogation of dopaminergic modulation of the multiple phases of reward-seeking behavior

Adamantidis, A. R., Tsai, H.-C., Boutrel, B., Zhang, F., Stuber, G. D., Budygin, E. A., Tourino, C., Bonci, A., Deisseroth, K., & de Lecea, L. (2011) · Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 357

Cardiogenic control of affective behavioural state

Hsueh, B., Chen, R., Jo, Y., Tang, D., Raffiee, M., Kim, Y. S., Inoue, M., Randles, S., Ramakrishnan, C., Patel, S., et al. (2023) · Nature

Heart Rate Variability and Autonomic ControlMemory and Neural Mechanisms

Cited by 335

Modulation of prefrontal cortex excitation/inhibition balance rescues social behavior in CNTNAP2 -deficient mice

Selimbeyoglu, A., Kim, C. K., Inoue, M., Lee, S. Y., Hong, A. S. O., Kauvar, I., Ramakrishnan, C., Fenno, L. E., Davidson, T. J., Wright, M., et al. (2017) · Science Translational Medicine

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 326

Glutamatergic signaling by mesolimbic dopamine neurons in the nucleus accumbens

Tecuapetla, F., Patel, J. C., Xenias, H., English, D., Tadros, I., Shah, F., Berlin, J., Deisseroth, K., Rice, M. E., Tepper, J. M., et al. (2010) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 310

Optical activation of lateral amygdala pyramidal cells instructs associative fear learning

Johansen, J. P., Hamanaka, H., Monfils, M. H., Behnia, R., Deisseroth, K., Blair, H. T., & LeDoux, J. E. (2010) · Proceedings of the National Academy of Sciences

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 308

Deep posteromedial cortical rhythm in dissociation

Vesuna, S., Kauvar, I. V., Richman, E., Gore, F., Oskotsky, T., Sava-Segal, C., Luo, L., Malenka, R. C., Henderson, J. M., Nuyujukian, P., et al. (2020) · Nature

Neural dynamics and brain functionMemory and Neural Mechanisms

Cited by 281

Optogenetic and potassium channel gene therapy in a rodent model of focal neocortical epilepsy

Wykes, R. C., Heeroma, J. H., Mantoan, L., Zheng, K., MacDonald, D. C., Deisseroth, K., Hashemi, K. S., Walker, M. C., Schorge, S., & Kullmann, D. M. (2012) · Science Translational Medicine

Epilepsy research and treatmentVirus-based gene therapy research

Cited by 272

5-HT release in nucleus accumbens rescues social deficits in mouse autism model

Walsh, J. J., Christoffel, D. J., Heifets, B. D., Ben-Dor, G. A., Selimbeyoglu, A., Hung, L. W., Deisseroth, K., & Malenka, R. C. (2018) · Nature

Autism Spectrum Disorder ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 256