Deisseroth, Karl

Intact-brain analyses reveal distinct information carried by SNc dopamine subcircuits

Lerner, T. N., Shilyansky, C., Davidson, T. J., Evans, K. E., Beier, K. T., Zalocusky, K. A., Crow, A. K., Malenka, R. C., Luo, L., Tomer, R., et al. (2015) · Cell

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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Principles for applying optogenetic tools derived from direct comparative analysis of microbial opsins

Mattis, J., Tye, K. M., Ferenczi, E. A., Ramakrishnan, C., O'Shea, D. J., Prakash, R., Gunaydin, L. A., Hyun, M., Fenno, L. E., Gradinaru, V., et al. (2012) · Nature Methods

Photoreceptor and optogenetics researchAdvanced Fluorescence Microscopy Techniques

Cited by 780

Ultrafast optogenetic control

Gunaydin, L. A., Yizhar, O., Berndt, A., Sohal, V. S., Deisseroth, K., & Hegemann, P. (2010) · Nature Neuroscience

Photoreceptor and optogenetics researchNeuroscience and Neural Engineering

Cited by 757

In vivo light-induced activation of neural circuitry in transgenic mice expressing channelrhodopsin-2

Arenkiel, B. R., Peca, J., Davison, I. G., Feliciano, C., Deisseroth, K., Augustine, G. J., Ehlers, M. D., & Feng, G. (2007) · Neuron

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 755

CLARITY for mapping the nervous system

Chung, K., & Deisseroth, K. (2013) · Nature Methods

Advanced Fluorescence Microscopy TechniquesHydrogels: synthesis, properties, applications

Cited by 747

Optogenetic investigation of neural circuits underlying brain disease in animal models

Tye, K. M., & Deisseroth, K. (2012) · Nature Reviews Neuroscience

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 745

Signaling from synapse to nucleus: postsynaptic CREB phosphorylation during multiple forms of hippocampal synaptic plasticity

Deisseroth, K., Bito, H., & Tsien, R. W. (1996) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 698

Optogenetic interrogation of neural circuits: technology for probing mammalian brain structures

Zhang, F., Gradinaru, V., Adamantidis, A. R., Durand, R., Airan, R. D., de Lecea, L., & Deisseroth, K. (2010) · Nature Protocols

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 692

Integration of optogenetics with complementary methodologies in systems neuroscience

Kim, C. K., Adhikari, A., & Deisseroth, K. (2017) · Nature reviews. Neuroscience

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 690

Recombinase-driver rat lines: tools, techniques, and optogenetic application to dopamine-mediated reinforcement

Witten, I. B., Steinberg, E. E., Lee, S. Y., Davidson, T. J., Zalocusky, K. A., Brodsky, M., Yizhar, O., Cho, S. L., Gong, S., Ramakrishnan, C., et al. (2011) · Neuron

Photoreceptor and optogenetics researchNeurotransmitter Receptor Influence on Behavior

Cited by 680

Excitation-Neurogenesis Coupling in Adult Neural Stem/Progenitor Cells

Deisseroth, K., Singla, S., Toda, H., Monje, M., Palmer, T. D., & Malenka, R. C. (2004) · Neuron

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 674

A critical role for NMDA receptors in parvalbumin interneurons for gamma rhythm induction and behavior

Carlén, M., Meletis, K., Siegle, J. H., Cardin, J. A., Futai, K., Vierling-Claassen, D., Rühlmann, C., Jones, S. R., Deisseroth, K., Sheng, M., et al. (2012) · Molecular Psychiatry

Neuroscience and Neuropharmacology ResearchNeural dynamics and brain function

Cited by 669

Diverging neural pathways assemble a behavioural state from separable features in anxiety

Kim, S.-Y., Adhikari, A., Lee, S. Y., Marshel, J. H., Kim, C. K., Mallory, C. S., Lo, M., Pak, S., Mattis, J., Lim, B. K., et al. (2013) · Nature

Memory and Neural MechanismsNeurotransmitter Receptor Influence on Behavior

Cited by 666

Cell type–specific channelrhodopsin-2 transgenic mice for optogenetic dissection of neural circuitry function

Zhao, S., Ting, J. T., Atallah, H. E., Qiu, L., Tan, J., Gloss, B., Augustine, G. J., Deisseroth, K., Luo, M., Graybiel, A. M., et al. (2011) · Nature Methods

Photoreceptor and optogenetics researchNeuroscience and Neuropharmacology Research

Cited by 653

Cortical layer-specific critical dynamics triggering perception

Marshel, J. H., Kim, Y. S., Machado, T. A., Quirin, S., Benson, B., Kadmon, J., Raja, C., Chibukhchyan, A., Ramakrishnan, C., Inoue, M., et al. (2019) · Science

Visual perception and processing mechanismsNeural dynamics and brain function

Cited by 652

A prefrontal cortex–brainstem neuronal projection that controls response to behavioural challenge

Warden, M. R., Selimbeyoglu, A., Mirzabekov, J. J., Lo, M., Thompson, K. R., Kim, S.-Y., Adhikari, A., Tye, K. M., Frank, L. M., & Deisseroth, K. (2012) · Nature

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 645

Sustained rescue of prefrontal circuit dysfunction by antidepressant-induced spine formation

Moda-Sava, R. N., Murdock, M. H., Parekh, P. K., Fetcho, R. N., Huang, B. S., Huynh, T. N., Witztum, J., Shaver, D. C., Rosenthal, D. L., Alway, E. J., et al. (2019) · Science

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 643

Antidepressant effect of optogenetic stimulation of the medial prefrontal cortex

Covington, H. E., Lobo, M. K., Maze, I., Vialou, V., Hyman, J. M., Zaman, S., LaPlant, Q., Mouzon, E., Ghose, S., Tamminga, C. A., et al. (2010) · The Journal of Neuroscience

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 621

Activation of specific interneurons improves V1 feature selectivity and visual perception

Lee, S.-H., Kwan, A. C., Zhang, S., Phoumthipphavong, V., Flannery, J. G., Masmanidis, S. C., Taniguchi, H., Huang, Z. J., Zhang, F., Boyden, E. S., et al. (2012) · Nature

Visual perception and processing mechanismsNeuroscience and Neuropharmacology Research

Cited by 593

Gating of social reward by oxytocin in the ventral tegmental area

Hung, L. W., Neuner, S., Polepalli, J. S., Beier, K. T., Wright, M., Walsh, J. J., Lewis, E. M., Luo, L., Deisseroth, K., Dölen, G., et al. (2017) · Science

Neuroendocrine regulation and behaviorNeurotransmitter Receptor Influence on Behavior

Cited by 578

Wirelessly powered, fully internal optogenetics for brain, spinal and peripheral circuits in mice

Montgomery, K. L., Yeh, A. J., Ho, J. S., Tsao, V., Mohan Iyer, S., Grosenick, L., Ferenczi, E. A., Tanabe, Y., Deisseroth, K., Delp, S. L., et al. (2015) · Nature Methods

Photoreceptor and optogenetics researchNeuroscience and Neural Engineering

Cited by 565

Targeting cells with single vectors using multiple-feature Boolean logic

Fenno, L. E., Mattis, J., Ramakrishnan, C., Hyun, M., Lee, S. Y., He, M., Tucciarone, J., Selimbeyoglu, A., Berndt, A., Grosenick, L., et al. (2014) · Nature Methods

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 557

Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior

Ferenczi, E. A., Zalocusky, K. A., Liston, C., Grosenick, L., Warden, M. R., Amatya, D., Katovich, K., Mehta, H., Patenaude, B., Ramakrishnan, C., et al. (2016) · Science

Neurotransmitter Receptor Influence on BehaviorNeural and Behavioral Psychology Studies

Cited by 535

Thalamic control of sensory selection in divided attention

Wimmer, R. D., Schmitt, L. I., Davidson, T. J., Nakajima, M., Deisseroth, K., & Halassa, M. M. (2015) · Nature

Visual perception and processing mechanismsMultisensory perception and integration

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