Autism as a disorder of neural information processing: Directions for research and targets for therapy
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Abstract
The broad variation in phenotypes and severities within autism spectrum disorders suggests the involvement of multiple predisposing factors, interacting in complex ways with normal developmental courses and gradients. Identification of these factors, and the common developmental path into which they feed, is hampered by the large degrees of convergence from causal factors to altered brain development, and divergence from abnormal brain development into altered cognition and behaviour. Genetic, neurochemical, neuroimaging, and behavioural findings on autism, as well as studies of normal development and of genetic syndromes that share symptoms with autism, offer hypotheses as to the nature of causal factors and their possible effects on the structure and dynamics of neural systems. Such alterations in neural properties may in turn perturb activity-dependent development, giving rise to a complex behavioural syndrome many steps removed from the root causes. Animal models based on genetic, neurochemical, neurophysiological, and behavioural manipulations offer the possibility of exploring these developmental processes in detail, as do human studies addressing endophenotypes beyond the diagnosis itself.
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Belmonte and colleagues proposed a unifying model based on imaging, electrophysiological, and anatomical data implicating abnormal neural connectivity that disrupts timing and information processing.
“Belmonte and colleagues have articulated a cogent unifying model based on imaging, electrophysiological and anatomical data, which implicates abnormal neural connectivity disrupting timing and information processing [51, 52].”
From Genetics of autism spectrum disorders (2011) · cites this paper as [52]
Models of ASD as a brain dysconnection syndrome have emerged from analyses of abnormalities in cortico-cortical connections.
“Models of ASD as a brain dysconnection syndrome (8-13) have emerged from analyses of abnormalities in cortico-cortical connections.”
From Aberrant Striatal Functional Connectivity in Children with Autism (2011) · cites this paper as [9]
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Cites
Lord, C., Rutter, M., & Le Couteur, A. (1994) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02172145 · Cited by 9,065 · see citing works
Does the autistic child have a “theory of mind” ?
Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985) · Cognition · doi:10.1016/0010-0277(85)90022-8 · Cited by 8,599 · cited 1× · see citing works
“…physiological measures (Figure 1) suggest that perceptual filtering in autism occurs in an all-or-none manner, with little specificity in selecting for the location of the stimulus, for the behavioural relevance of the stimulus, or even for the sensory modality in which the stimulus appears.”
BackgroundInfluence of life stress on depression: moderation by a polymorphism in the 5-HTT gene
Caspi, A., Sugden, K., Moffitt, T. E., Taylor, A., Craig, I. W., Harrington, H., McClay, J., Mill, J., Martin, J., Braithwaite, A., et al. (2003) · Science · doi:10.1126/science.1083968 · Cited by 8,120 · see citing works
Rett syndrome is caused by mutations in X-linked MECP2, encoding methyl-CpG-binding protein 2
Amir, R. E., Van den Veyver, I. B., Wan, M., Tran, C. Q., Francke, U., & Zoghbi, H. Y. (1999) · Nature Genetics · doi:10.1038/13810 · Cited by 4,990 · see citing works
Epigenetic Reprogramming in Mammalian Development
Reik, W., Dean, W., & Walter, J. (2001) · Science · doi:10.1126/science.1063443 · Cited by 3,078 · see citing works
Model of autism: increased ratio of excitation/inhibition in key neural systems
Rubenstein, J. L. R., & Merzenich, M. M. (2003) · Genes, Brain and Behavior · doi:10.1034/j.1601-183x.2003.00037.x · Cited by 2,768 · see citing works
Self-citationHandbook of Autism and Pervasive Developmental Disorders
(2005) · Wiley eBooks · doi:10.1002/9780470939352 · Cited by 2,252 · see citing works
Regional Development of the Brain in Early Life
(1968) · Archives of Disease in Childhood · doi:10.1136/adc.43.229.388 · Cited by 2,107 · see citing works
The extreme male brain theory of autism
Baron-Cohen, S. (2002) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(02)01904-6 · Cited by 2,007 · see citing works
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism
Study, P. A. R. I. S., Jamain, S., Quach, H., Betancur, C., Råstam, M., Colineaux, C., Gillberg, I. C., Soderstrom, H., Giros, B., Leboyer, M., et al. (2003) · Nature Genetics · doi:10.1038/ng1136 · Cited by 1,851 · see citing works
Executive function deficits in high-functioning autistic individuals: Relationship to theory of mind
Ozonoff, S., Pennington, B. F., & Rogers, S. J. (1991) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1991.tb00351.x · Cited by 1,766 · see citing works
(1967) · Medical Entomology and Zoology · Cited by 1,713 · see citing works
BRAFF, D. L., Geyer, M. A., & Swerdlow, N. R. (2001) · Psychopharmacology · doi:10.1007/s002130100810 · Cited by 1,701 · see citing works
Unusual brain growth patterns in early life in patients with autistic disorder: An MRI study
Courchesne, E., Karns, C. M., Davis, H. R., Ziccardi, R., Carper, R. A., Tigue, Z. D., Chisum, H. J., Moses, P., Pierce, K., Lord, C., et al. (2001) · Neurology · doi:10.1212/wnl.57.2.245 · Cited by 1,487 · see citing works
Self-citationGeyer, M. A., Krebs-Thomson, K., Braff, D. L., & Swerdlow, N. R. (2001) · Psychopharmacology · doi:10.1007/s002130100811 · Cited by 1,484 · see citing works
Absence of expression of the FMR-1 gene in fragile X syndrome
Pieretti, M., Zhang, F., Fu, Y.-H., Warren, S. T., Oostra, B. A., Caskey, C. T., & Nelson, D. L. (1991) · Cell · doi:10.1016/0092-8674(91)90125-i · Cited by 1,476 · see citing works
Autism: beyond “theory of mind”
Frith, U., & Happé, F. (1994) · Cognition · doi:10.1016/0010-0277(94)90024-8 · Cited by 1,450 · see citing works
The Extreme Male-Brain Theory of Autism
Baron‐Cohen, S. (1999) · The MIT Press eBooks · doi:10.7551/mitpress/4945.003.0023 · Cited by 1,413 · see citing works
Castelli, F. (2002) · Brain · doi:10.1093/brain/awf189 · Cited by 1,377 · see citing works
Social intelligence in the normal and autistic brain: An fMRI study
Baron‐Cohen, S., Ring, H. A., Wheelwright, S., Bullmore, E. T., Brammer, M. J., Simmons, A., & Williams, S. C. R. (1999) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1999.00621.x · Cited by 1,320 · see citing works
Are Rare Variants Responsible for Susceptibility to Complex Diseases?
Pritchard, J. K. (2001) · The American Journal of Human Genetics · doi:10.1086/321272 · Cited by 1,197 · see citing works
The spectrum of behaviors influenced by serotonin
Lucki, I. (1998) · Biological Psychiatry · doi:10.1016/s0006-3223(98)00139-5 · Cited by 1,154 · see citing works
Psychopharmacology: The Fourth Generation of Progress
Green, A. I. (1996) · Psychiatric Services · doi:10.1176/ps.47.3.312 · Cited by 1,151 · see citing works
Laurie, D., Wisden, W., & Seeburg, P. (1992) · Journal of Neuroscience · doi:10.1523/jneurosci.12-11-04151.1992 · Cited by 1,144 · see citing works
Pervasive Developmental Disorders in preschool children
Chakrabarti, S. (2001) · JAMA · doi:10.1001/jama.285.24.3093 · Cited by 1,132 · see citing works
Evidence of Brain Overgrowth in the First Year of Life in Autism
Courchesne, E. (2003) · JAMA · doi:10.1001/jama.290.3.337 · Cited by 1,120 · see citing works
Self-citationThe more or less startling effects of weak prestimulation
Graham, F. K. (1975) · Psychophysiology · doi:10.1111/j.1469-8986.1975.tb01284.x · Cited by 1,119 · see citing works
Hypoplasia of cerebellar vermal lobules VI and VII in autism
Courchesne, E., Yeung-Courchesne, R., Hesselink, J. R., & Jernigan, T. L. (1988) · New England Journal of Medicine · doi:10.1056/nejm198805263182102 · Cited by 1,058 · see citing works
Self-citationSwerdlow, N. R., Geyer, M. A., & BRAFF, D. L. (2001) · Psychopharmacology · doi:10.1007/s002130100799 · Cited by 1,053 · see citing works
A long, remarkable journey: Tangential migration in the telencephalon
Marín, Ó., & Rubenstein, J. L. R. (2001) · Nature reviews. Neuroscience · doi:10.1038/35097509 · Cited by 1,050 · see citing works
Self-citationAbnormal dendritic spines in fragile X knockout mice: Maturation and pruning deficits
Comery, T. A., Harris, J. B., Willems, P. J., Oostra, B. A., Irwin, S. A., Weiler, I. J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5401 · Cited by 1,046 · see citing works
Self-citationSocial Intelligence in the Normal and Autistic Brain: An fMRI Study
Baron‐Cohen, S., RING, H. A., Wheelwright, S. J., Bullmore, E. T., Brammer, M. J., Simmons, A., & Williams, S. (2002) · The MIT Press eBooks · doi:10.7551/mitpress/3077.003.0028 · Cited by 1,044 · see citing works
Baranek, G. T. (1999) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1023080005650 · Cited by 1,027 · see citing works
Maternal influenza infection causes marked behavioral and pharmacological changes in the offspring
Shi, L., Fatemi, S. H., Sidwell, R. W., & Patterson, P. H. (2003) · The Journal of Neuroscience · doi:10.1523/jneurosci.23-01-00297.2003 · Cited by 1,025 · see citing works
Schultz, R. T., Gauthier, I., Klin, A., Fulbright, R. K., Anderson, A. W., Volkmar, F., Skudlarski, P., Lacadie, C., Cohen, D. J., & Gore, J. C. (2000) · Archives of General Psychiatry · doi:10.1001/archpsyc.57.4.331 · Cited by 1,000 · see citing works
Histoanatomic observations of the brain in early infantile autism
Bauman, M., & Kemper, T. L. (1985) · Neurology · doi:10.1212/wnl.35.6.866 · Cited by 964 · see citing works
Brain structural abnormalities in young children with autism spectrum disorder
Sparks, B. F., Friedman, S. D., Shaw, D. W., Aylward, E. H., Echelard, D., Artru, A. A., Maravilla, K. R., Giedd, J. N., Munson, J., Dawson, G., et al. (2002) · Neurology · doi:10.1212/wnl.59.2.184 · Cited by 961 · see citing works
Why Do Autistic Individuals Show Superior Performance on the Block Design Task?
Shah, A., & Uta Frith, A. (1993) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1993.tb02095.x · Cited by 941 · see citing works
Local GABA Circuit Control of Experience-Dependent Plasticity in Developing Visual Cortex
Hensch, T. K., Fagiolini, M., Mataga, N., Stryker, M. P., Baekkeskov, S., & Kash, S. F. (1998) · Science · doi:10.1126/science.282.5393.1504 · Cited by 910 · see citing works
Face processing occurs outside the fusiform ‘face area’ in autism: evidence from functional MRI
Pierce, K. (2001) · Brain · doi:10.1093/brain/124.10.2059 · Cited by 898 · see citing works
An islet of ability in autistic children: a research note
Shah, A., & Frith, U. (1983) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1983.tb00137.x · Cited by 888 · see citing works
Jiang, Y.-H., Armstrong, D., Albrecht, U., Atkins, C. M., Noebels, J. L., Eichele, G., Sweatt, J. D., & Beaudet, A. L. (1998) · Neuron · doi:10.1016/s0896-6273(00)80596-6 · Cited by 852 · see citing works
Self-citationMinicolumnar pathology in autism
Casanova, M. F., Buxhoeveden, D. P., Switala, A. E., & Roy, E. (2002) · Neurology · doi:10.1212/wnl.58.3.428 · Cited by 846 · see citing works
Functional requirement for class I MHC in CNS development and plasticity
Huh, G. S., Boulanger, L. M., Du, H., Riquelme, P. A., Brotz, T. M., & Shatz, C. J. (2000) · Science · doi:10.1126/science.290.5499.2155 · Cited by 828 · see citing works
Self-citationThe functional neuroanatomy of social behaviour
Critchley, H. D., Daly, E. M., Bullmore, E. T., Williams, S. C. R., Van Amelsvoort, T., Robertson, D. M., Rowe, A., Phillips, M., McAlonan, G., Howlin, P., et al. (2000) · Brain · doi:10.1093/brain/123.11.2203 · Cited by 816 · see citing works
Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome
Tint, G. S., Irons, M., Elias, E. R., Batta, A. K., Frieden, R., Chen, T. S., & Salen, G. (1994) · New England Journal of Medicine · doi:10.1056/nejm199401133300205 · Cited by 798 · see citing works
A theoretical approach to the deficits in infantile autism
Rogers, S. J., & Pennington, B. F. (1991) · Development and Psychopathology · doi:10.1017/s0954579400000043 · Cited by 784 · see citing works
Genetics of austim: complex aetiology for a heterogeneous disorder
Folstein, S. E., & Rosen-Sheidley, B. (2001) · Nature Reviews Genetics · doi:10.1038/35103559 · Cited by 771 · see citing works
Evidence from Turner's syndrome of an imprinted X-linked locus affecting cognitive function
Skuse, D. H., James, R. S., Bishop, D. V. M., Coppin, B., Dalton, P., Aamodt-Leeper, G., Bacarese-Hamilton, M., Creswell, C., McGurk, R., & Jacobs, P. A. (1997) · Nature · doi:10.1038/42706 · Cited by 747 · see citing works
FMR1 Protein: Conserved RNP Family Domains and Selective RNA Binding
Ashley, C. T., Wilkinson, K. D., Reines, D., & Warren, S. T. (1993) · Science · doi:10.1126/science.7692601 · Cited by 741 · see citing works
Assessing the Validity of an Animal Model of Deficient Sensorimotor Gating in Schizophrenic Patients
Swerdlow, N. R. (1994) · Archives of General Psychiatry · doi:10.1001/archpsyc.1994.03950020063007 · Cited by 708 · see citing works
A Genomic Screen of Autism: Evidence for a Multilocus Etiology
Risch, N., Spiker, D., Lotspeich, L., Nouri, N., Hinds, D., Hallmayer, J., Kalaydjieva, L., McCague, P., Dimiceli, S., Pitts, T., et al. (1999) · The American Journal of Human Genetics · doi:10.1086/302497 · Cited by 684 · see citing works
Localization of white matter volume increase in autism and developmental language disorder
Herbert, M. R., Ziegler, D. A., Makris, N., Filipek, P. A., Kemper, T. L., Normandin, J. J., Sanders, H. A., Kennedy, D. N., & Caviness, V. S. (2004) · Annals of Neurology · doi:10.1002/ana.20032 · Cited by 663 · see citing works
To Model a Psychiatric Disorder in Animals Schizophrenia As a Reality Test
Lipska, B. K. (2000) · Neuropsychopharmacology · doi:10.1016/s0893-133x(00)00137-8 · Cited by 650 · see citing works
A newly recognized syndromeof multiple congenital anomalies
Smith, D. W., Lemli, L., & Opitz, J. M. (1964) · The Journal of Pediatrics · doi:10.1016/s0022-3476(64)80264-x · Cited by 650 · see citing works
Impairment in shifting attention in autistic and cerebellar patients.
Courchesne, E., Townsend, J., Akshoomoff, N. A., Saitoh, O., Yeung-Courchesne, R., Lincoln, A. J., James, H. E., Haas, R., Schreibman, L., & Lau, L. (1994) · Behavioral Neuroscience · doi:10.1037//0735-7044.108.5.848 · Cited by 647 · see citing works
Self-citationImpairment in shifting attention in autistic and cerebellar patients
Courchesne, E., Townsend, J., Akshoomoff, N. A., Saitoh, O., Yeung-Courchesne, R., Lincoln, A. J., James, H. E., Haas, R. H., Schreibman, L., & Lau, L. (1994) · Behavioral Neuroscience · doi:10.1037/0735-7044.108.5.848 · Cited by 647 · see citing works
Self-citationWeiler, I. J., Irwin, S. A., Klintsova, A. Y., Spencer, C. M., Brazelton, A. D., Miyashiro, K., Comery, T. A., Patel, B., Eberwine, J., & Greenough, W. T. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.10.5395 · Cited by 644 · cited 1× · see citing works
“involves FMRP occurs at synapses in response to Group I metabotropic receptor activation [257].”
BackgroundMind Blindness and the Brain in Autism
Frith, U. (2001) · Neuron · doi:10.1016/s0896-6273(01)00552-9 · Cited by 637 · see citing works
Superior visual search in autism.
O'riordan, M., Plaisted, K., Driver, J., & Baron-Cohen, S. (2001) · Journal of Experimental Psychology: Human Perception and Performance · doi:10.1037/0096-1523.27.3.719 · Cited by 624 · see citing works
(1986) · American Journal of Psychiatry · doi:10.1176/ajp.143.7.862 · Cited by 590 · see citing works
The Mammalian Startle Response
Davis, M. (1984) · Springer eBooks · doi:10.1007/978-1-4899-2286-1_10 · Cited by 582 · see citing works
Studies on 5-hydroxyindole metabolism in autistic and other mentally retarded children
Schain, R. J., & Freedman, D. X. (1961) · The Journal of Pediatrics · doi:10.1016/s0022-3476(61)80261-8 · Cited by 579 · see citing works
Environmental Noise Retards Auditory Cortical Development
Chang, E. F., & Merzenich, M. M. (2003) · Science · doi:10.1126/science.1082163 · Cited by 573 · see citing works
Alcántara, S., Ruiz, M., D’Arcangelo, G., Ezan, F., de Lecea, L., Curran, T., Sotelo, C., & Soriano, E. (1998) · The Journal of Neuroscience · doi:10.1523/jneurosci.18-19-07779.1998 · Cited by 568 · see citing works
Cerebral Lobes in Autism: Early Hyperplasia and Abnormal Age Effects
Carper, R. (2002) · NeuroImage · doi:10.1006/nimg.2002.1099 · Cited by 566 · see citing works
Superior visual search in autism.
O’Riordan, M., Plaisted, K. C., Driver, J., & Baron‐Cohen, S. (2001) · Journal of Experimental Psychology Human Perception & Performance · doi:10.1037//0096-1523.27.3.719 · Cited by 557 · see citing works
Regulation of Class I MHC Gene Expression in the Developing and Mature CNS by Neural Activity
Corriveau, R. A., Huh, G. S., & Shatz, C. J. (1998) · Neuron · doi:10.1016/s0896-6273(00)80562-0 · Cited by 548 · see citing works
Anderson, S. A., Qiu, M. S., Bulfone, A., Eisenstat, D. D., Meneses, J. J., Pedersen, R. A., & Rubenstein, J. L. R. (1997) · Neuron · doi:10.1016/s0896-6273(00)80345-1 · Cited by 541 · see citing works
Self-citationReduced antinociception in mice lacking neuronal nicotinic receptor subunits
Marubio, L. M., Jiménez, M. D. M. A., Cordero‐Erausquin, M., Léna, C., Novère, N. G. L., d’Exaerde, A. D. K., Huchet, M., Damaj, M. I., & Changeux, J. (1999) · Nature · doi:10.1038/19756 · Cited by 533 · see citing works
Quantitative Trait Locus for Reading Disability on Chromosome 6
Cardon, L. R., Smith, S. D., Fulker, D. W., Kimberling, W. J., Pennington, B. F., & DeFries, J. C. (1994) · Science · doi:10.1126/science.7939663 · Cited by 533 · see citing works
Analysis of neocortex in three males with the Fragile X syndrome
Hinton, V. J., Brown, W. T., Wisniewski, K., & Rudelli, R. D. (1991) · American Journal of Medical Genetics · doi:10.1002/ajmg.1320410306 · Cited by 527 · see citing works
The development of autism: Perspectives from theory and research.
Howlin, P. (2002) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.t01-9-00044 · Cited by 526 · see citing works
MRI volumes of amygdala and hippocampus in non–mentally retarded autistic adolescents and adults
Aylward, E., Minshew, N. J., Goldstein, G., Honeycutt, N. A., Augustine, A. M., Yates, K. O., Barta, P. E., & Pearlson, G. D. (1999) · Neurology · doi:10.1212/wnl.53.9.2145 · Cited by 513 · see citing works
Serotonin and brain development: role in human developmental diseases
Whitaker-Azmitia, P. M. (2001) · Brain Research Bulletin · doi:10.1016/s0361-9230(01)00615-3 · Cited by 506 · see citing works
Effects of age on brain volume and head circumference in autism
Aylward, E., Minshew, N. J., Field, K., Sparks, B. F., & Singh, N. (2002) · Neurology · doi:10.1212/wnl.59.2.175 · Cited by 496 · see citing works
RNA cargoes associating with FMRP reveal deficits in cellular functioning in Fmr1 null mice
Miyashiro, K. Y., Beckel-Mitchener, A., Purk, T. P., Becker, K. G., Barret, T., Liu, L., Carbonetto, S., Weiler, I. J., Greenough, W. T., & Eberwine, J. (2003) · Neuron · doi:10.1016/s0896-6273(03)00034-5 · Cited by 495 · see citing works
Self-citationDissociations of cerebral cortex, subcortical and cerebral white matter volumes in autistic boys
Herbert, M. R., Ziegler, D. A., Deutsch, C., O’Brien, L. M., LANGE, N. D., Bakardjiev, A. I., Hodgson, J. M., Adrien, K. T., Steele, S., Makris, N., et al. (2003) · Brain · doi:10.1093/brain/awg110 · Cited by 494 · see citing works
Rogers, S. J., Wehner, E. A., & Hagerman, R. J. (2001) · Journal of Developmental & Behavioral Pediatrics · doi:10.1097/00004703-200112000-00008 · Cited by 487 · see citing works
Effect of nicotine and nicotinic receptors on anxiety and depression
Picciotto, M. R., Brunzell, D. H., & Caldarone, B. J. (2002) · Neuroreport · doi:10.1097/00001756-200207020-00006 · Cited by 483 · see citing works
Homanics, G. E., DeLorey, T. M., Firestone, L. L., Quinlan, J. J., Handforth, A., Harrison, N. L., Krasowski, M. D., Rick, C., Korpi, E. R., Mäkelä, R., et al. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.8.4143 · Cited by 469 · see citing works
Self-citationEvidence for a cerebellar role in reduced exploration and stereotyped behavior in autism
Pierce, K., & Courchesne, E. (2001) · Biological Psychiatry · doi:10.1016/s0006-3223(00)01008-8 · Cited by 464 · see citing works
Self-citationDeLorey, T. M., Handforth, A., Anagnostaras, S., Homanics, G. E., Minassian, B. A., Asatourian, A., Fanselow, M. S., Delgado‐Escueta, A. V., Ellison, G., & Olsen, R. W. (1998) · Journal of Neuroscience · doi:10.1523/jneurosci.18-20-08505.1998 · Cited by 459 · see citing works
Self-citationA Genomewide Screen for Autism: Strong Evidence for Linkage to Chromosomes 2q, 7q, and 16p
(2001) · The American Journal of Human Genetics · doi:10.1086/323264 · Cited by 453 · see citing works
What's in a face? The case of autism
Hobson, R. P., Ouston, J., & Lee, A. L. (1988) · British Journal of Psychology · doi:10.1111/j.2044-8295.1988.tb02745.x · Cited by 452 · see citing works
Brain anatomy and sensorimotor gating in Asperger's syndrome
McAlonan, G. M. (2002) · Brain · doi:10.1093/brain/awf150 · Cited by 447 · see citing works
Swerdlow, N. R., Paulsen, J. S., BRAFF, D. L., Butters, N., Geyer, M. A., & Swenson, M. R. (1995) · Journal of Neurology Neurosurgery & Psychiatry · doi:10.1136/jnnp.58.2.192 · Cited by 436 · see citing works
Familial Clustering of Autoimmune Disorders and Evaluation of Medical Risk Factors in Autism
Comi, A., Zimmerman, A., Frye, V. H., Law, P., & Peeden, J. (1999) · Journal of Child Neurology · doi:10.1177/088307389901400608 · Cited by 427 · see citing works
Plaisted, K., Swettenham, J., & Rees, L. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00489 · Cited by 409 · see citing works
A Normed Study of Face Recognition in Autism and Related Disorders
Klin, A., Sparrow, S. S., de Bildt, A. A., Cicchetti, D. V., Cohen, D. J., & Volkmar, F. R. (1999) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1022299920240 · Cited by 408 · see citing works
Brainstem, cerebellar and limbic neuroanatomical abnormalities in autism
Courchesne, E. (1997) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(97)80016-5 · Cited by 401 · see citing works
Self-citationSensorimotor gating in boys with Tourette's syndrome and ADHD: Preliminary results
Castellanos, F. X., Fine, E. J., Kaysen, D. L., Marsh, W., Rapoport, J. L., & Hallett, M. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00101-8 · Cited by 395 · see citing works
The serotonin system in autism
Cook, E. H., & LEVENTHAL, B. L. (1996) · Current Opinion in Pediatrics · doi:10.1097/00008480-199608000-00008 · Cited by 394 · see citing works
Self-citationPickles, A. R., Bolton, P., Macdonald, H., Bailey, A., Couteur, A. S. L., Sim, C. H., & Rutter, M. L. (1995) · Europe PMC (PubMed Central) · Cited by 388 · see citing works
Hippocampus in autism: a Golgi analysis
Raymond, G. V., Bauman, M. L., & Kemper, T. L. (1995) · Acta Neuropathologica · doi:10.1007/s004010050401 · Cited by 387 · see citing works
Development of the brainstem and cerebellum in autistic patients
Hashimoto, T., Tayama, M., Murakawa, K., Yoshimoto, T., Miyazaki, M., Harada, M., & Kuroda, Y. (1995) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02178163 · Cited by 381 · see citing works
Ingram, J. L., Peckham, S. M., Tisdale, B., & Rodier, P. M. (2000) · Neurotoxicology and Teratology · doi:10.1016/s0892-0362(99)00083-5 · Cited by 381 · see citing works
Defective cholesterol biosynthesis in Smith-Lemli-Opitz syndrome
Irons, M., Roy Elias, E., Salen, G., Tint, G. S., & Batta, A. (1993) · The Lancet · doi:10.1016/0140-6736(93)90983-n · Cited by 368 · see citing works
Enhanced Perceptual Functioning in the Development of Autism
Burack, J. A., Charman, T., Yirmiya, N., & Zelazo, P. R. (2001) · Routledge eBooks · doi:10.4324/9781410600196-14 · Cited by 366 · see citing works
Parents of Children with Asperger Syndrome: What is the Cognitive Phenotype?
Baron‐Cohen, S., & Hammer, J. (1997) · Journal of Cognitive Neuroscience · doi:10.1162/jocn.1997.9.4.548 · Cited by 363 · see citing works
Unfamiliar Face Recognition in Relatively Able Autistic Children
Boucher, J., & LEWIS, V. A. (1992) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1992.tb01960.x · Cited by 363 · see citing works
Reduced Size of Corpus Callosum in Autism
Egaas, B., Courchesne, E., & Saitoh, O. (1995) · Archives of Neurology · doi:10.1001/archneur.1995.00540320070014 · Cited by 361 · see citing works
Self-citationLipska, B. K., Weinberger, D. R., Swerdlow, N. R., Geyer, M. A., BRAFF, D. L., & Jaskiw, G. E. (1995) · Psychopharmacology · doi:10.1007/bf02246439 · Cited by 356 · see citing works
A preliminary assessment of sensorimotor gating in patients with obsessive compulsive disorder
Swerdlow, N. R., Benbow, C. H., Zisook, S., Geyer, M. A., & BRAFF, D. L. (1993) · Biological Psychiatry · doi:10.1016/0006-3223(93)90300-3 · Cited by 351 · see citing works
Plaisted, K. C., Swettenham, J., & Rees, L. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1017/s0021963099004102 · Cited by 340 · see citing works
Animal models of psychiatric disorders
Koob, G. F., & Zimmer, A. (2012) · Handbook of clinical neurology · doi:10.1016/b978-0-444-52002-9.00009-7 · Cited by 337 · see citing works
Powell, E. M., Campbell, D. B., Stanwood, G. D., Davis, C., Noebels, J. L., & Levitt, P. R. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-02-00622.2003 · Cited by 333 · see citing works
Self-citationInverse correlation between frontal lobe and cerebellum sizes in children with autism
Carper, R. A. (2000) · Brain · doi:10.1093/brain/123.4.836 · Cited by 333 · see citing works
Happe, F. G. E., Uta Frith, A., & Briskman, J. (2001) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00723 · Cited by 331 · see citing works
Blatt, G. J., Fitzgerald, C. M., Guptill, J. T., Booker, A. B., Kemper, T. L., & Bauman, M. L. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1013238809666 · Cited by 322 · see citing works
Association between a GABRB3 polymorphism and autism
Buxbaum, J. D., Silverman, J. M., Smith, C. J. W., Greenberg, D. A., Kilifarski, M., Reichert, J. G., Cook, E. H., Fang, Y., Song, C.-Y., & Vitale, R. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001011 · Cited by 322 · see citing works
Self-citationWilliams, R. S. (1980) · Archives of Neurology · doi:10.1001/archneur.1980.00500610029003 · Cited by 318 · see citing works
Synaptic regulation of protein synthesis and the fragile X protein
Greenough, W. T., Klintsova, A. Y., Irwin, S. A., Galvez, R., Bates, K. E., & Weiler, I. J. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.141145998 · Cited by 317 · see citing works
Self-citationCerebral correlates of preserved cognitive skills in autism
RING, H. A., Baron‐Cohen, S., Wheelwright, S. J., Williams, S., Brammer, M. J., Andrew, C., & Bullmore, E. T. (1999) · Brain · doi:10.1093/brain/122.7.1305 · Cited by 306 · see citing works
Regulation of receptor function by cholesterol
Bürger, K., Gimpl, G., & Fahrenholz, F. (2000) · Cellular and Molecular Life Sciences · doi:10.1007/pl00000643 · Cited by 302 · see citing works
Geschwind, D. H., Sowinski, J., Lord, C., Iversen, P., Shestack, J., Jones, P., Ducat, L., & Spence, S. J. (2001) · The American Journal of Human Genetics · doi:10.1086/321292 · Cited by 302 · see citing works
Autistic Children's Ability to Interpret Faces: A Research Note
Tantam, D., Monaghan, L., Nicholson, H., & Stirling, J. (1989) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1989.tb00274.x · Cited by 298 · see citing works
Autonomic responses of autistic children to people and objects
Hirstein, W., Iversen, P., & Ramachandran, V. S. (2001) · Proceedings of the Royal Society of London. Series B: Biological Sciences · doi:10.1098/rspb.2001.1724 · Cited by 297 · see citing works
Courchesne, E., Townsend, J., & Saitoh, O. (1994) · Neurology · doi:10.1212/wnl.44.2.214 · Cited by 296 · see citing works
Self-citationPharmacogenetics and the serotonin system: initial studies and future directions
Veenstra-VanderWeele, J. M., Anderson, G. M., & Cook, E. H. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00814-1 · Cited by 289 · see citing works
Self-citationCourchesne, E., Saitoh, O., Yeung-Courchesne, R., Press, G. A., Lincoln, A. J., Haas, R. H., & Schreibman, L. (1994) · American Journal of Roentgenology · doi:10.2214/ajr.162.1.8273650 · Cited by 278 · see citing works
Self-citationAntibodies to Myelin Basic Protein in Children with Autistic Behavior
Singh, V. K., Warren, R. P., Odell, J. D., Warren, W. L., & Cole, P. (1993) · Brain, Behavior, and Immunity · doi:10.1006/brbi.1993.1010 · Cited by 274 · see citing works
Spatial attention deficits in patients with acquired or developmental cerebellar abnormality
Townsend, J., Courchesne, E., Covington, J., Westerfield, M., Harris, N. S., Lyden, P., Lowry, T. P., & Press, G. A. (1999) · The Journal of Neuroscience · doi:10.1523/jneurosci.19-13-05632.1999 · Cited by 272 · see citing works
Self-citationMaternal infection: window on neuroimmune interactions in fetal brain development and mental illness
Patterson, P. H. (2002) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(02)00299-4 · Cited by 269 · see citing works
Gait Disturbances in Patients With Autistic Behavior
Vilensky, J. A. (1981) · Archives of Neurology · doi:10.1001/archneur.1981.00510100074013 · Cited by 268 · see citing works
Functional anatomy of impaired selective attention and compensatory processing in autism
Belmonte, M. K., & Yurgelun-Todd, D. A. (2003) · Cognitive Brain Research · doi:10.1016/s0926-6410(03)00189-7 · Cited by 266 · see citing works
Self-citationThe effects of an early stressful life event on sensorimotor gating in adult rats
Ellenbroek, B. A., van den Kroonenberg, P. T. J. M., & Cools, A. R. (1998) · Schizophrenia Research · doi:10.1016/s0920-9964(97)00149-7 · Cited by 265 · see citing works
Fatemi, S. H., Earle, J., Kanodia, R., Kist, D., Emamian, E. S., Patterson, P. H., Shi, L., & Sidwell, R. (2002) · Cellular and Molecular Neurobiology · doi:10.1023/a:1015337611258 · Cited by 261 · see citing works
Autistic behavior in young boys with fragile X syndrome
Bailey, D. B., Mesibov, G. B., Hatton, D. D., Clark, R. D., Roberts, J. E., & Mayhew, L. (1998) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1026048027397 · Cited by 260 · see citing works
Ectopic expression of the Dlx genes induces glutamic acid decarboxylase and Dlx expression
Stühmer, T., Anderson, S. A., Ekker, M., & Rubenstein, J. L. R. (2002) · Development · doi:10.1242/dev.129.1.245 · Cited by 257 · see citing works
Self-citationTh1- and Th2-like cytokines in CD4+ and CD8+ T cells in autism
Gupta, S., Aggarwal, S., Rashanravan, B., & Lee, T. (1998) · Journal of Neuroimmunology · doi:10.1016/s0165-5728(98)00021-6 · Cited by 250 · see citing works
Engineering chromosomal rearrangements in mice
Yu, Y., & Bradley, A. (2001) · Nature Reviews Genetics · doi:10.1038/35093564 · Cited by 244 · see citing works
L1 knockout mice show dilated ventricles, vermis hypoplasia and impaired exploration patterns
Fransén, E. (1998) · Human Molecular Genetics · doi:10.1093/hmg/7.6.999 · Cited by 244 · see citing works
Alkondon, M., & Albuquerque, E. X. (2001) · Journal of Neurophysiology · doi:10.1152/jn.2001.86.6.3043 · Cited by 240 · see citing works
The Incidence of Cognitive Disabilities in the Siblings of Autistic Children
August, G. J., Stewart, M. A., & Tsai, L. (1981) · The British Journal of Psychiatry · doi:10.1192/bjp.138.5.416 · Cited by 238 · see citing works
Serum autoantibodies to brain in Landau-Kleffner variant, autism, and other neurologic disorders
Connolly, A. M., Chez, M. G., Pestronk, A., Arnold, S. T., Mehta, S., & Deuel, R. K. (1999) · The Journal of Pediatrics · doi:10.1016/s0022-3476(99)70248-9 · Cited by 236 · see citing works
Reduced Cerebellar Hemisphere Size and Its Relationship to Vermal Hypoplasia in Autism
Murakami, J. W., Courchesne, E., Press, G. A., Yeung-Courchesne, R., & Hesselink, J. R. (1989) · Archives of Neurology · doi:10.1001/archneur.1989.00520420111032 · Cited by 235 · see citing works
Self-citationIdentification of MeCP2 mutations in a series of females with autistic disorder
Carney, R. M., Wolpert, C. M., Ravan, S. A., Shahbazian, M. D., Ashley‐Koch, A. E., Cuccaro, M. L., Vance, J. M., & Pericak‐Vance, M. A. (2003) · Pediatric Neurology · doi:10.1016/s0887-8994(02)00624-0 · Cited by 234 · see citing works
Circulating autoantibodies to neuronal and glial filament proteins in autism
Singh, V. K., Warren, R., Averett, R., & Ghaziuddin, M. (1997) · Pediatric Neurology · doi:10.1016/s0887-8994(97)00045-3 · Cited by 234 · see citing works
Nicotinic receptor abnormalities in the cerebellar cortex in autism
Lee, M. (2002) · Brain · doi:10.1093/brain/awf160 · Cited by 232 · see citing works
Smith-Lemli-Opitz syndrome: a variable clinical and biochemical phenotype.
Ryan, A. K., Bartlett, K., Clayton, P. T., Eaton, S. D., Mills, L., Donnai, D., Winter, R. M., & Burn, J. (1998) · Journal of Medical Genetics · doi:10.1136/jmg.35.7.558 · Cited by 231 · see citing works
DeFelipe, J., Hendry, S. H. C., Hashikawa, T., Molinari, M., & Jones, E. G. (1990) · Neuroscience · doi:10.1016/0306-4522(90)90097-n · Cited by 231 · see citing works
The phenotypic characteristics of heterozygous reeler mouse
Tueting, P. A., Costa, E., Dwivedi, Y. K., Guidotti, A., Impagnatiello, F., Manev, R. M., & Pesold, C. (1999) · Neuroreport · doi:10.1097/00001756-199904260-00032 · Cited by 221 · see citing works
Visual orienting deficits in high-functioning people with autism
Wainwright-Sharp, J. A., & Bryson, S. E. (1993) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01066415 · Cited by 221 · see citing works
Parietal lobe abnormalities detected with MR in patients with infantile autism.
Courchesne, E., Press, G. A., & Yeung-Courchesne, R. (1993) · American Journal of Roentgenology · doi:10.2214/ajr.160.2.8424359 · Cited by 214 · see citing works
Self-citationThe Hyperserotonemia of Autisma
Anderson, G. M., Horne, W. C., Chatterjee, D., & Cohen, D. J. (1990) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1990.tb16893.x · Cited by 210 · see citing works
Self-citationPersonality characteristics of the parents of autistic individuals
Piven, J., Wzorek, M., Landa, R., Lainhart, J., Bolton, P., Chase, G. A., & Folstein, S. (1994) · Psychological Medicine · doi:10.1017/s0033291700027938 · Cited by 210 · see citing works
Hallett, M., Lebiedowska, M. K., Thomas, S. L., Stanhope, S. J., Denckla, M. B., & Rumsey, J. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540120019007 · Cited by 209 · see citing works
Bailey, D. B., Hatton, D. D., Skinner, M. L., & Mesibov, G. B. (2001) · Journal of Autism and Developmental Disorders · doi:10.1023/a:1010747131386 · Cited by 207 · see citing works
Immune abnormalities in patients with autism
Warren, R. P., Margaretten, N. C., Pace, N. C., & Foster, A. (1986) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01531729 · Cited by 207 · see citing works
A Family History Study of Neuropsychiatric Disorders in the Adult Siblings of Autistic Individuals
Piven, J., GAYLE, J., Chase, G. A., FINK, B., Landa, R. J., Wzorek, M., & Folstein, S. E. (1990) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-199003000-00004 · Cited by 204 · see citing works
Maternal neuronal antibodies associated with autism and a language disorder
Dalton, P., Deacon, R., Blamire, A., Pike, M., McKinlay, I., Stein, J., Styles, P., & Vincent, A. (2003) · Annals of Neurology · doi:10.1002/ana.10557 · Cited by 204 · see citing works
Depressed lymphocyte responsiveness in autistic children
Stubbs, E. G., Crawford, M. L., Burger, D. R., & Vandenbark, A. A. (1977) · Journal of Autism and Childhood Schizophrenia · doi:10.1007/bf01531114 · Cited by 202 · see citing works
Nicotinic receptor subtypes in human brain ageing, Alzheimer and Lewy body diseases
Perry, E. K., Martin-Ruiz, C. M., Lee, M., Griffiths, M., Johnson, M., Piggott, M. A., Haroutunian, V. H., Buxbaum, J. D., Nãsland, J., Davis, K. L., et al. (2000) · European Journal of Pharmacology · doi:10.1016/s0014-2999(00)00064-9 · Cited by 201 · see citing works
Self-citationA Family Study of Autism: Cognitive Patterns and Levels in Parents and Siblings
Fombonne, E. J., Bolton, P., Prior, J., Jordan, H., & Rutter, M. L. (1997) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1997.tb01694.x · Cited by 200 · see citing works
Expression from a Dlx Gene Enhancer Marks Adult Mouse Cortical GABAergic Neurons
Stühmer, T. (2002) · Cerebral Cortex · doi:10.1093/cercor/12.1.75 · Cited by 198 · see citing works
Role of the serotonin transporter gene in the behavioral expression of autism
Tordjman, S., Gutknecht, L., Carlier, M., Spitz, E., Antoine, C., Slama, F., Carsalade, V, Cohen, D. J., Ferrari, P., Roubertoux, P. L., et al. (2001) · Molecular Psychiatry · doi:10.1038/sj.mp.4000873 · Cited by 196 · see citing works
Self-citationEnvironmental animal models for sensorimotor gating deficiencies in schizophrenia: a review
Weiss, I. C., & Feldon, J. (2001) · Psychopharmacology · doi:10.1007/s002130100800 · Cited by 194 · see citing works
Complex segregation analysis of autism.
Jorde, L. B., Hasstedt, S. J., RITVO, E. R., MASON-BROTHERS, A., Freeman, B. J., Pingree, C., McMahon, W. M., Petersen, B., Jenson, W. R., & Mo, A. (1991) · PubMed · Cited by 191 · see citing works
Reduced Natural Killer Cell Activity in Autism
WARREN, R. P., FOSTER, A., & MARGARETTEN, N. C. (1987) · Journal of the American Academy of Child & Adolescent Psychiatry · doi:10.1097/00004583-198705000-00008 · Cited by 190 · see citing works
Does Autism Occur More Often in Families of Physicists, Engineers, and Mathematicians?
Baron‐Cohen, S. (1998) · Autism · doi:10.1177/1362361398023008 · Cited by 189 · see citing works
The Neurobiology of Infantile Autism
Ciaranello, A. L., & Ciaranello, R. D. (1995) · Annual Review of Neuroscience · doi:10.1146/annurev.ne.18.030195.000533 · Cited by 184 · see citing works
Plaisted, K. C., Saksida, L. M., Alcántara, J. I., & Weisblatt, E. J. L. (2003) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2002.1211 · Cited by 183 · see citing works
Executive function in parents of children with autism.
HUGHES, C., LEBOYER, M., & BOUVARD, M. (1997) · Psychological Medicine · doi:10.1017/s0033291796004308 · Cited by 181 · see citing works
A Deficit in Shifting Attention Present in High-Functioning Autism but not Asperger’s Disorder
Rinehart, N., Bradshaw, J. L., Moss, S. A., Brereton, A. V., & Tonge, B. J. (2001) · Autism · doi:10.1177/1362361301005001007 · Cited by 181 · see citing works
Nicotinic receptors in human brain: topography and pathology
Court, J. A., Martin-Ruiz, C., Graham, A., & Perry, E. (2000) · Journal of Chemical Neuroanatomy · doi:10.1016/s0891-0618(00)00110-1 · Cited by 180 · see citing works
Self-citationLindor, N. M., Furuichi, Y., Kitao, S., Shimamoto, A., Arndt, C., & Jalal, S. M. (2000) · American Journal of Medical Genetics · doi:10.1002/(sici)1096-8628(20000131)90:3 · Cited by 176 · see citing works
Ison, J. R., McAdam, D., & Hammond, G. L. (1973) · Physiology & Behavior · doi:10.1016/0031-9384(73)90185-6 · Cited by 175 · see citing works
Ciesielski, K. T., Courchesne, E., & Elmasian, R. (1990) · Electroencephalography and Clinical Neurophysiology · doi:10.1016/0013-4694(90)90174-i · Cited by 175 · see citing works
Self-citationAbnormal early brain development in autism
Courchesne, E. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001169 · Cited by 175 · see citing works
Self-citationSaitoh, O. (2001) · Brain · doi:10.1093/brain/124.7.1317 · Cited by 175 · see citing works
Müller, R.-A., Kleinhans, N. M., Kemmotsu, N., Pierce, K., & Courchesne, E. (2003) · American Journal of Psychiatry · doi:10.1176/appi.ajp.160.10.1847 · Cited by 174 · see citing works
Self-citationVisual attention abnormalities in autism: delayed orienting to location
Townsend, J., Harris, N. S., & Courchesne, E. (1996) · Journal of the International Neuropsychological Society · doi:10.1017/s1355617700001715 · Cited by 172 · see citing works
Self-citationNeuronal plasticity and cellular immunity: shared molecular mechanisms
Boulanger, L. M., Huh, G. S., & Shatz, C. J. (2001) · Current Opinion in Neurobiology · doi:10.1016/s0959-4388(00)00251-8 · Cited by 171 · see citing works
Self-citationIs There a Link between Engineering and Autism?
Baron‐Cohen, S., Wheelwright, S. J., Stott, C., Bolton, P., & Goodyer, I. M. (1997) · Autism · doi:10.1177/1362361397011010 · Cited by 170 · see citing works
Cholinergic regulation of cortical development and plasticity. New twists to an old story.
Cf, H., & Berger-Sweeney, J. E. (1998) · PubMed · Cited by 165 · see citing works
Neuroanatomic contributions to slowed orienting of attention in children with autism
Harris, N. S., Courchesne, E., Townsend, J., Carper, R. A., & Lord, C. (1999) · Cognitive Brain Research · doi:10.1016/s0926-6410(99)00006-3 · Cited by 164 · see citing works
Self-citationHughes, C. H., Plumet, M., & Leboyer, M. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00487 · Cited by 164 · see citing works
Auditory event-related brain potentials in autistic children and three different control groups
Kemner, C., Verbaten, M. N., Cuperus, J. M., Camfferman, G., & van Engeland, H. (1995) · Biological Psychiatry · doi:10.1016/0006-3223(94)00247-z · Cited by 160 · see citing works
Berry, D. S., & Zebrowitz-McArthur, L. (1988) · Personality and Social Psychology Bulletin · doi:10.1177/0146167288141003 · Cited by 160 · see citing works
Autistic Social Dysfunction: Some Limitations of the Theory of Mind Hypothesis
Klin, A. J., Volkmar, F. R., & Sparrow, S. S. (1992) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1992.tb01961.x · Cited by 159 · see citing works
Predictors of Cognitive Test Patterns in Autism Families
Folstein, S. E., Santangelo, S. L., Gilman, S. E., Piven, J., Landa, R. J., Lainhart, J. E., Hein, J., & Wzorek, M. (1999) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00528 · Cited by 158 · see citing works
Chromosomal abnormalities in a clinic sample of individuals with autistic disorder
Wassink, T. H., Piven, J., & Patil, S. R. (2001) · Psychiatric Genetics · doi:10.1097/00041444-200106000-00001 · Cited by 157 · see citing works
Plasma β‐Endorphin, Adrenocorticotropin Hormone, and Cortisol in Autism
Tordjman, S., McBride, P., Hertzig, M. E., Snow, M. E., Anderson, G. M., Hall, L. M., Thompson, S., Ferrari, P., & Cohen, D. J. (1997) · Journal of Child Psychology and Psychiatry · doi:10.1111/j.1469-7610.1997.tb01697.x · Cited by 152 · see citing works
Self-citationTownsend, J., Westerfield, M., Leaver, E., Makeig, S., Jung, T.-P., Pierce, K., & Courchesne, E. (2001) · Cognitive Brain Research · doi:10.1016/s0926-6410(00)00072-0 · Cited by 151 · see citing works
Self-citationKim, S.-J., Cox, N. J., Yeung-Courchesne, R., Lord, C., Corsello, C. M., Akshoomoff, N., Guter, S. J., LEVENTHAL, B. L., Courchesne, E., & Cook, E. H. (2002) · Molecular Psychiatry · doi:10.1038/sj.mp.4001033 · Cited by 150 · see citing works
Self-citationRole of L1 in Neural Development: What the Knockouts Tell Us
Kamiguchi, H., Hlavin, M. L., & Lemmon, V. (1998) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1998.0702 · Cited by 147 · see citing works
Non‐human primate models of childhood psychopathology: the promise and the limitations
Machado, C. J., & Bachevalier, J. (2002) · Journal of Child Psychology and Psychiatry · doi:10.1111/1469-7610.00103 · Cited by 146 · see citing works
Neuroimaging of typical and atypical development: A perspective from multiple levels of analysis
Johnson, M. H., Halit, H., Grice, S. J., & Karmiloff‐Smith, A. (2002) · Development and Psychopathology · doi:10.1017/s0954579402003073 · Cited by 145 · see citing works
The neurobiological basis of autism from a developmental perspective
Akshoomoff, N. A., Pierce, K., & Courchesne, E. (2002) · Development and Psychopathology · doi:10.1017/s0954579402003115 · Cited by 145 · see citing works
Self-citationPathophysiologic findings in nonretarded autism and receptive developmental language disorder
Courchesne, E., Lincoln, A. J., Yeung-Courchesne, R., Elmasian, R., & Grillon, C. (1989) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02212714 · Cited by 144 · see citing works
Self-citationTownsend, J., Courchesne, E., & Egaas, B. (1996) · Development and Psychopathology · doi:10.1017/s0954579400007276 · Cited by 139 · see citing works
Self-citationSymptom domains in autism and related conditions: evidence for familiality.
Silverman, J., Smith, C. J., Schmeidler, J., Hollander, E., Lawlor, B., Fitzgerald, M., Buxbaum, J., Delaney, K., & Galvin, P. (2002) · American journal of medical genetics · doi:10.1002/ajmg.10048 · Cited by 138 · see citing works
Ornitz, E. M., Hanna, G. L., & de Traversay, J. (1992) · Psychophysiology · doi:10.1111/j.1469-8986.1992.tb01717.x · Cited by 137 · see citing works
McCauley, J. L., Olson, L. M., Dowd, M., Amin, T. T., Steele, A., Blakely, R., Folstein, S. E., Haines, J. L., & Sutcliffe, J. S. (2003) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.20151 · Cited by 136 · see citing works
Abnormal immune response to brain tissue antigen in the syndrome of autism
Weizman, A., Weizman, R., Szekely, G. A., Wijsenbeek, H., & Livni, E. (1982) · American Journal of Psychiatry · doi:10.1176/ajp.139.11.1462 · Cited by 136 · see citing works
DLX5 Regulates Development of Peripheral and Central Components of the Olfactory System
Long, J. E., Garel, S., Depew, M. J., Tobet, S. A., & Rubenstein, J. L. R. (2003) · Journal of Neuroscience · doi:10.1523/jneurosci.23-02-00568.2003 · Cited by 131 · see citing works
Self-citationHardan, A. Y., & Handen, B. L. (2002) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/104454602760386923 · Cited by 130 · see citing works
Strong association of the third hypervariable region of HLA-DRβ1 with autism
Warren, R. P., Odell, J. D., Warren, W. L., Burger, R. A., Maciulis, A., Daniels, W. W., & Torres, A. R. (1996) · Journal of Neuroimmunology · doi:10.1016/0165-5728(96)00052-5 · Cited by 130 · see citing works
Pletnikov, M. V., Rubin, S. A., Vasudevan, K., Moran, T. H., & Carbone, K. M. (1999) · Behavioural Brain Research · doi:10.1016/s0166-4328(98)00111-9 · Cited by 129 · see citing works
Flagged first, then by citations
Research works printed but not linked: 42
- [1][1] Ader R, Felton DL, Cohen N (eds). Psychoneuroimmunology 2/e. Academic Press: San Diego, 1991. -
- [7][7] Anderson GM, Horne WC, Chatterjee D, Cohen DJ. The hyperserotonemia of autism. Ann NY Acad Sci 1990; 600 :331-340. -
- [16][16] Ballaban-Gil K, Tuchman R. Epilepsyand epileptiform EEG: association with autism and language disorders. Ment Retard Dev Disabil Res Rev 2000; 6 :300-308. -
- [18][18] Baron-Cohen S. The extreme male brain theoryof autism. Trends Cogn Sci 2002; 6 :248-254. -
- [21][21] Baron-Cohen S, Leslie AM, Frith U. Does the autistic child have a 'theoryof mind'? Cognition 1985; 21 :37-46. -
- [24][24] Bauman ML, Kemper TL. Histoanatomic observations of the brain in earlyinfantile autism. Neurology 1985; 35 :866-874. -
- [29][29] Belmonte MK, Yurgelun-Todd DA. Functional Anatomyof Impaired Selective Attention and CompensatoryProcessing in Autism. Cogn Brain Res 2003; 17 :651-664. -
- [30][30] Belser RC, Sudhalter V. Arousal difficulties in males with fragile X syndrome: a preliminary report. Dev Brain Dysfunct 1995; 8 :270-279. -
- [33][33] Boucher J, Lewis V. Unfamiliar face recognition in relativelyable autistic children. J Child Psychol Psychiatry 1992; 33 :843-859. -
- [34][34] Boulanger LM, Huh GS, Shatz CJ. Neuronal plasticityand cellular immunity : shared molecular mechanisms. Curr Opin Neurobiol 2001; 11 :568-578. -
- [37][37] Burger K, Gimpl G, Fahrenholz F. Regulation of receptor function bycholesterol. Cell Mol Life Sci 2000; 57 :1577-1592. -
- [39][39] Bzd´ uch V, Behulova D, Skodova. Incidence of Smith-Lemli-Opitz syndrome in Slovakia. J Am Med Genet 2000; 90 :260. -
- [40][40] Cardon LR, Smith SD, Fulker DW, Kimberling WJ, Pennington BF, DeFries JC. Quantitative trait locus for reading disabilityon chromosome 6. Science 1994; 266 :276-279. -
- [44][44] Casanova MF, Buxhoeveden DP, Switala AE, RoyE. Minicolumnar pathologyin autism. Neurology 2002; 58 :428-432. -
- [51][51] Chang EF, Merzenich MM. Environmental noise retards auditorycortical development. Science 2003; 300 :498-502. -
- [52][52] Ciaranello AL, Ciaranello RD. The neurobiologyof infantile autism. Annu Rev Neurosci 1995; 18 :101-128. -
- [64][64] Courchesne E. Abnormal earlybrain development in autism. Mol Psychiatry 2002; 7 :S21-23. -
- [75][75] Court JA, Martin-Ruiz C, Graham A, PerryE. Nicotinic receptors in human brain: topographyand pathology. J Chem Neuroanat 2000; 20 :281-298. -
- [76][76] CritchleyHD, DalyEM, Bullmore ET, Williams SCR, Van Amelsvoort T, Robertson DM, Rowe A, Phillips M, McAlonan G, Howlin P, MurphyDGM. The functional neuroanatomyof social behaviour: changes in cerebral blood flow when people with autistic disorder process facial expressions. Brain 2000; 123 :2203-2212. -
- [78][78] Daniels WW, Warren RP, Odell JD, Maciulis A, Burger RA, Warren WL, Torres AR. Increased frequencyof the extended or ancestral haploty pe B44-SC30-DR4 in autism. Neuropsychobiology 1995; 32 :120-123. -
- [82][82] DeLoreyTM, Handforth A, Anagnostaras SG, Homanics GE, Minassian BA, Asatourian A, Fanselow MS, Delgado-Escueta A, Ellison GD, Olsen RW. Mice lacking the β 3 subunit of the GABA A receptor have the epilepsyphenoty pe and manyof the behavioral characteristics of Angelman sy ndrome. J Neurosci 1998; 18 :8505-8514. -
- [88][88] Folstein SE, Rosen-SheidleyB. Genetics of autism: complex aetiologyfor a heterogeneous disorder. Nat Rev Genet 2001; 2 :943-955. -
- [89][89] Fombonne E, Bolton P, Prior J, Jordan H, Rutter M. A familystudyof autism: cognitive patterns and levels in parents and siblings. J Child Psychol Psychiatry 1997; 38 :667-683. -
- [91][91] Frith U, Autism: Explaining the Enigma . Blackwell: Oxford, 1989. -
- [95][95] Geschwind DH, Sowinski J, Lord C, Iversen P, Shestack J, Jones P, Ducat L, Spence SJ. The autism genetic resource exchange: a resource for the studyof autism and related neuropsy chiatric conditions. Am J Hum Genet 2001; 69 :463-466. -
- [120][120] Irons M, Elias ER, Salen G, Tint GS, Batta AK. Defective cholesterol biosynthesis in Smith-LemliOpitz syndrome. Lancet 1993; 341 :1414. -
- [123][123] Ison JR, McAdam DW, Hammond GR. Latencyand amplitude changes in the acoustic startle reflex produced byvariations in auditoryprestimulation. Physiol Behav 1973; 10 :1035-1039. -
- [132][132] KelleyRI, Hennekam RCH. Smith-Lemli-Opitz Sy ndrome. In: Scriver CR, Beaudet AL, SlyWS, Valle D. (eds) The Metabolic and Molecular Basis of Inherited Disease 8/e. McGraw Hill: New York, 2000. -
- [138][138] Krause I, He X-S, Gershwin ME, Shoenfeld Y. Immune factors in autism: a critical review. J Autism Devel Disord 2002; 32 :337-345. -
- [141][141] Lamb JA, Parr JR, BaileyAJ, Monaco AP. Autism: in search of susceptibilitygenes. Neuromolecular Med 2002; 2 :11-28. -
- [151][151] Lucki I. The spectrum of behaviors influenced byserotonin. Biol Psychiatry 1998; 44 :151-162. -
- [155][155] McAlonan GM, DalyE, Kumari V, CritchleyHD, van Amelsvoort T, Suckling J, Simmons A, Sigmundsson T, Greenwood K, Russell A, Schmitz N, Happe F, Howlin P, MurphyDG. Brain anatomyand sensorimotor gating in Asperger's sy ndrome. Brain 2002; 125 :1594-1606. -
- [156][156] Miller LJ, McIntosh DN, McGrath J, Shyu V, Lampe M, Taylor AK, Tassone F, Neitzel K, Stackhouse T, Hagerman RJ. Electrodermal responses to sensorystimuli in individuals with fragile X sy ndrome: a preliminaryreport. Am J Med Genet 1999; 83 :268-279. -
- [160][160] M¨ uller R-A, Kleinhans N, Kemmotsu N, Pierce K, Courchesne E. Abnormal variabilityand distribution of functional maps in autism: an fMRI studyof visuomotor learning. Am J Psychiatry 2003; 160 :1847-1862. -
- [179][179] Piven J, Wzorek M, Landa R, Lainhart J, Bolton P, Chase GA, Folstein S. Personalitycharacteristics of the parents of autistic individuals. Psychol Med 1994; 24 :783-795. -
- [186][186] Pritchard JK. Are rare variants responsible for susceptibilityto complex diseases? Am J Hum Genet 2001; 69 :124-137. -
- [193][193] Rodier PM, Hyman SL. Early environmental factors in autism. Ment Retard Dev Disability Res Reviews 1998; 4 :121-128. -
- [213][213] Smith DW, Lemli L, Opitz JM. A newlyrecognized sy ndrome of multiple congenital anomalies. J Pediatr 1964; 64 :210-217. -
- [214][214] Smith IM. Motor functioning in Asperger's syndrome. In: Klin A, Volkmar FR, Sparrow SS. (eds) Asperger's Syndrome. The Guildford Press: New York, 2000. -
- [216][216] Stevens S, Gruzelier J. Electrodermal activityto auditorystimuli in autistic, retarded, and normal children. J Autism Dev Disord 1984; 14 :245-260. -
- [228][228] Toichi M, Kamio Y. Long-term memoryand levels-of-processing in autism. Neuropsychologia 2002; 40 :964-969. -
- [250][250] Warren RP, Foster A, Margaretten NC. Reduced natural killer cell activityin autism. J Amer Acad Child Adolesc Psychiatry 1987; 26 :333-335. -
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- Authors
- Belmonte, M. K., Cook, E. H., Anderson, G. M., Rubenstein, J. L. R., Greenough, W. T., Beckel-Mitchener, A., Courchesne, E., Boulanger, L. M., Powell, S. B., Levitt, P. R., Perry, E. K., Jiang, Y. H., DeLorey, T. M., & Tierney, E.
- Affiliations
- University of Cambridge (GB)
- University of Chicago (US)
- Yale University (US)
- University of California, San Francisco (US)
- University of Illinois Urbana-Champaign (US)
- University of California San Diego (US)
- Harvard University (US)
- Vanderbilt University (US)
- Newcastle University (GB)
- Baylor College of Medicine (US)
- Molecular Research Institute (US)
- Kennedy Krieger Institute (US)
- Corresponding author
- Belmonte, M K
- ORCID
- Venue
- Molecular Psychiatry
- Published
- 2004-03-23
- Volume
- 9
- Issue
- 7
- Pages
- 646-663
- ISSN
- 1359-4184 (ISSN-L)
- 1476-5578
- OpenAlex
- W2139092938
- Cited by
- 442
- References
- 274
- Citations by year
- 2026: 7 · 2025: 8 · 2024: 13 · 2023: 10 · 2022: 9 · 2021: 21 · 2020: 16 · 2019: 13 · 2018: 13 · 2017: 22 · 2016: 14 · 2015: 30 · 2014: 21 · 2013: 31 · 2012: 24
- FWCI
- 2.05
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Molecular Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Nottingham Trent University's Institutional Repository (Nottingham Trent Repository) (acceptedVersion)
- PsyArXiv (OSF Preprints) (submittedVersion)
- PsyArXiv (OSF Preprints) (submittedVersion, cc-by)
- Newcastle University ePrints (Newcastle Univesity)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Autism Spectrum Disorder Research
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genetics and Neurodevelopmental Disorders
- Social Sciences › Psychology › Social Psychology › Neuroendocrine regulation and behavior
- Keywords
- autism spectrum disorder, neural information processing, brain development, developmental trajectories, genetic syndromes, endophenotypes, animal models, activity-dependent development, neuroimaging, genetic susceptibility, autism treatment
- MeSH terms
- Animals, Autistic Disorder, Cognition Disorders, Humans
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