Lightman, Stafford L.

The HPA axis in major depression: classical theories and new developments

Pariante, C. M., & Lightman, S. L. (2008) · Trends in Neurosciences

Stress Responses and CortisolAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 2,009

The human stress response

Russell, G., & Lightman, S. (2019) · Nature Reviews Endocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 1,032

The effects of improving sleep on mental health (OASIS): a randomised controlled trial with mediation analysis

Freeman, D., Sheaves, B., Goodwin, G. M., Yu, L.-M., Nickless, A., Harrison, P. J., Emsley, R., Luik, A. I., Foster, R. G., Wadekar, V., et al. (2017) · The Lancet Psychiatry

Sleep and related disordersDigital Mental Health Interventions

Cited by 652

The Functional and Clinical Significance of the 24-Hour Rhythm of Circulating Glucocorticoids

Oster, H., Challet, E., Ott, V., Arvat, E., de Kloet, E. R., Dijk, D.-J., Lightman, S., Vgontzas, A., & Van Cauter, E. (2017) · Endocrine Reviews

Circadian rhythm and melatoninAdrenal Hormones and Disorders

Cited by 548

Tryptophan metabolism in the central nervous system: medical implications

Ruddick, J. P., Evans, A. K., Nutt, D. J., Lightman, S. L., Rook, G. A. W., & Lowry, C. A. (2006) · Expert Reviews in Molecular Medicine

Tryptophan and brain disordersAmino Acid Enzymes and Metabolism

Cited by 519

Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding

Biddie, S. C., John, S., Sabo, P. J., Thurman, R. E., Johnson, T. A., Schiltz, R. L., Miranda, T. B., Sung, M.-H., Trump, S., Lightman, S. L., et al. (2011) · Molecular Cell

Genomics and Chromatin DynamicsEstrogen and related hormone effects

Cited by 503

Chronic stress in elderly carers of dementia patients and antibody response to influenza vaccination

Vedhara, K., Cox, N. K., Wilcock, G. K., Perks, P., Hunt, M., Anderson, S., Lightman, S. L., & Shanks, N. M. (1999) · The Lancet

Stress Responses and CortisolNursing care and research

Cited by 496

Dynamics of ACTH and Cortisol Secretion and Implications for Disease

Lightman, S. L., Birnie, M. T., & Conway-Campbell, B. L. (2020) · Endocrine Reviews

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 439

Role of glucocorticoid negative feedback in the regulation of HPA axis pulsatility

Gjerstad, J. K., Lightman, S. L., & Spiga, F. (2018) · Stress

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 437

Oxytocin Attenuates Stress-Induced c-fos mRNA Expression in Specific Forebrain Regions Associated with Modulation of Hypothalamo–Pituitary–Adrenal Activity

Windle, R. J., Kershaw, Y. M., Shanks, N., Wood, S. A., Lightman, S. L., & Ingram, C. D. (2004) · The Journal of Neuroscience

Neuroendocrine regulation and behaviorStress Responses and Cortisol

Cited by 408

Circadian Rhythms of Epinephrine and Norepinephrine in Man*

LINSELL, C. R., LIGHTMAN, S. L., MULLEN, P. E., BROWN, M. J., & CAUSON, R. C. (1985) · The Journal of Clinical Endocrinology & Metabolism

Circadian rhythm and melatoninSleep and Work-Related Fatigue

Cited by 399

The crucial role of pulsatile activity of the HPA axis for continuous dynamic equilibration

Lightman, S. L., & Conway-Campbell, B. L. (2010) · Nature Reviews Neuroscience

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 390

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription

Stavreva, D. A., Wiench, M., John, S., Conway-Campbell, B. L., McKenna, M. A., Pooley, J. R., Johnson, T. A., Voss, T. C., Lightman, S. L., & Hager, G. L. (2009) · Nature Cell Biology

Estrogen and related hormone effectsAdrenal Hormones and Disorders

Cited by 375

Early-life exposure to endotoxin alters hypothalamic-pituitary-adrenal function and predisposition to inflammation

Shanks, N., Windle, R. J., Perks, P. A., Harbuz, M. S., Jessop, D. S., Ingram, C. D., & Lightman, S. L. (2000) · Proceedings of the National Academy of Sciences

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 374

Cortisol pulsatility and its role in stress regulation and health

YOUNG, E., ABELSON, J., & LIGHTMAN, S. (2004) · Frontiers in Neuroendocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 355

Changes in oxytocin and vasopressin secretion during sexual activity in men

MURPHY, M. R., SECKL, J. R., BURTON, S., CHECKLEY, S. A., & LIGHTMAN, S. L. (1987) · The Journal of Clinical Endocrinology & Metabolism

Neuroendocrine regulation and behaviorSexual function and dysfunction studies

Cited by 318

Corticosterone levels in the brain show a distinct ultradian rhythm but a delayed response to forced swim stress

Droste, S. K., de Groote, L., Atkinson, H. C., Lightman, S. L., Reul, J. M. H. M., & Linthorst, A. C. E. (2008) · Endocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 280

Ultradian rhythm of basal corticosterone release in the female rat: dynamic interaction with the response to acute stress

Windle, R. J., Wood, S. A., Shanks, N., Lightman, S. L., & Ingram, C. D. (1998) · Endocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 276

HPA Axis‐Rhythms

Spiga, F., Walker, J. J., Terry, J. R., & Lightman, S. L. (2014) · Comprehensive Physiology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 267

Gonadectomy reverses the sexually diergic patterns of circadian and stress-induced hypothalamic-pituitary-adrenal axis activity in male and female rats

Seale, J. V., Wood, S. A., Atkinson, H. C., Bate, E., Lightman, S. L., Ingram, C. D., Jessop, D. S., & Harbuz, M. S. (2004) · Journal of Neuroendocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 243

The significance of glucocorticoid pulsatility

Lightman, S. L., Wiles, C. C., Atkinson, H. C., Henley, D. E., Russell, G. M., Leendertz, J. A., McKenna, M. A., Spiga, F., Wood, S. A., & Conway-Campbell, B. L. (2008) · European Journal of Pharmacology

Stress Responses and CortisolEstrogen and related hormone effects

Cited by 241

Origin of ultradian pulsatility in the hypothalamic–pituitary–adrenal axis

Walker, J. J., Terry, J. R., & Lightman, S. L. (2010) · Proceedings of the Royal Society B: Biological Sciences

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 239

Corticotropin-Releasing Factor Increases In Vitro Firing Rates of Serotonergic Neurons in the Rat Dorsal Raphe Nucleus: Evidence for Activation of a Topographically Organized Mesolimbocortical Serotonergic System

Lowry, C. A., Rodda, J. E., Lightman, S. L., & Ingram, C. D. (2000) · The Journal of Neuroscience

Neuropeptides and Animal PhysiologyStress Responses and Cortisol

Cited by 211

Research priorities for the COVID‐19 pandemic and beyond: A call to action for psychological science

O'Connor, D. B., Aggleton, J. P., Chakrabarti, B., Cooper, C. L., Creswell, C., Dunsmuir, S., Fiske, S. T., Gathercole, S., Gough, B., Ireland, J. L., et al. (2020) · British Journal of Psychology

COVID-19 and Mental HealthSocial impacts of COVID-19

Cited by 210