Smith, Mark A.

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Klionsky, D. J., Abeliovich, H., Agostinis, P., Agrawal, D. K., Aliev, G., Askew, D. S., Baba, M., Baehrecke, E. H., Bahr, B. A., Ballabio, A., et al. (2008) · Autophagy

Autophagy in Disease and TherapyCellular transport and secretion

Cited by 2,230

Oxidative Damage Is the Earliest Event in Alzheimer Disease

Nunomura, A., Perry, G., Aliev, G., Hirai, K., Takeda, A., Balraj, E. K., Jones, P. K., Ghanbari, H., Wataya, T., Shimohama, S., et al. (2001) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,885

Mitochondrial abnormalities in Alzheimer's disease

Hirai, K., Aliev, G., Nunomura, A., Fujioka, H., Russell, R. L., Atwood, C. S., Johnson, A. B., Kress, Y., Vinters, H. V., Tabaton, M., et al. (2001) · The Journal of Neuroscience

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 1,367

Widespread Peroxynitrite-Mediated Damage in Alzheimer’s Disease

Smith, M. A., Richey Harris, P. L., Sayre, L. M., Beckman, J. S., & Perry, G. (1997) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 1,239

Impaired Balance of Mitochondrial Fission and Fusion in Alzheimer's Disease

Wang, X., Su, B., Lee, H.-G., Li, X., Perry, G., Smith, M. A., & Zhu, X. (2009) · Journal of Neuroscience

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 1,224

Oxidative stress in Alzheimer’s disease

Smith, M. A., Rottkamp, C. A., Nunomura, A., Raina, A. K., & Perry, G. (2000) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 895

Mitochondrial dysfunction is a trigger of Alzheimer's disease pathophysiology

Moreira, P. I., Carvalho, C., Zhu, X., Smith, M. A., & Perry, G. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Alzheimer's disease research and treatmentsMitochondrial Function and Pathology

Cited by 734

Involvement of oxidative stress in Alzheimer disease

Nunomura, A., Castellani, R. J., Zhu, X., Moreira, P. I., Perry, G., & Smith, M. A. (2006) · Journal of Neuropathology and Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 611

Glycated tau protein in Alzheimer disease: a mechanism for induction of oxidant stress.

Yan, S. D., Chen, X., Schmidt, A. M., Brett, J., Godman, G., Zou, Y. S., Scott, C. W., Caputo, C., Frappier, T., & Smith, M. A. (1994) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsAdvanced Glycation End Products research

Cited by 565

Alzheimer Disease and Oxidative Stress

Perry, G., Cash, A. D., & Smith, M. A. (2002) · BioMed Research International

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 455

Non-enzymatically glycated tau in Alzheimer's disease induces neuronal oxidant stress resulting in cytokine gene expression and release of amyloid β-peptide

Yan, S. D., Yan, S. F., Chen, X., Fu, J., Chen, M., Kuppusamy, P., Smith, M. A., Perry, G., Godman, G. C., Nawroth, P., et al. (1995) · Nature Medicine

Alzheimer's disease research and treatmentsAdvanced Glycation End Products research

Cited by 406

Oxidative stress increases expression and activity of BACE in NT2 neurons

Tamagno, E., Bardini, P., Obbili, A., Vitali, A., Borghi, R., Zaccheo, D., Pronzato, M. A., Danni, O., Smith, M. A., Perry, G., et al. (2002) · Neurobiology of Disease

Alzheimer's disease research and treatmentsAntioxidant Activity and Oxidative Stress

Cited by 385

Activation of p38 Kinase Links Tau Phosphorylation, Oxidative Stress, and Cell Cycle-Related Events in Alzheimer Disease

Zhu, X., Rottkamp, C. A., Boux, H., Takeda, A., Perry, G., & Smith, M. A. (2000) · Journal of Neuropathology & Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 378

Causes of oxidative stress in Alzheimer disease

Zhu, X., Su, B., Wang, X., Smith, M. A., & Perry, G. (2007) · Cellular and Molecular Life Sciences

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 336

Melatonin increases survival and inhibits oxidative and amyloid pathology in a transgenic model of Alzheimer's disease

Matsubara, E., Bryant‐Thomas, T., Pacheco Quinto, J., Henry, T. L., Poeggeler, B., Herbert, D., Cruz‐Sanchez, F., Chyan, Y., Smith, M. A., Perry, G., et al. (2003) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsCircadian rhythm and melatonin

Cited by 332

β‐Site APP cleaving enzyme up‐regulation induced by 4‐hydroxynonenal is mediated by stress‐activated protein kinases pathways

Tamagno, E., Parola, M., Bardini, P., Piccini, A., Borghi, R., Guglielmotto, M., Santoro, G., Davit, A., Danni, O., Smith, M. A., et al. (2005) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 324

Activation of NADPH Oxidase in Alzheimer’s Disease Brains

Shimohama, S., Tanino, H., Kawakami, N., Okamura, N., Kodama, H., Yamaguchi, T., Hayakawa, T., Nunomura, A., Chiba, S., Perry, G., et al. (2000) · Biochemical and Biophysical Research Communications

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 292

Ribosomal RNA in Alzheimer Disease Is Oxidized by Bound Redox-active Iron

Honda, K., Smith, M. A., Zhu, X., Baus, D., Merrick, W. C., Tartakoff, A. M., Hattier, T., Harris, P. L., Siedlak, S. L., Fujioka, H., et al. (2005) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsRedox biology and oxidative stress

Cited by 280

Sequestration of iron by Lewy bodies in Parkinson's disease

Castellani, R. J., Siedlak, S. L., Perry, G., & Smith, M. A. (2000) · Acta Neuropathologica

Parkinson's Disease Mechanisms and TreatmentsNeurological diseases and metabolism

Cited by 265

Abnormal Mitochondrial Dynamics in the Pathogenesis of Alzheimer's Disease

Zhu, X., Perry, G., Smith, M. A., & Wang, X. (2012) · Journal of Alzheimer's Disease

Mitochondrial Function and PathologyAlzheimer's disease research and treatments

Cited by 242

Insulin-resistant brain state: The culprit in sporadic Alzheimer's disease?

Correia, S. C., Santos, R. X., Perry, G., Zhu, X., Moreira, P. I., & Smith, M. A. (2011) · Ageing Research Reviews

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 212

The mosaic of brain glial hyperactivity during normal ageing and its attenuation by food restriction

Morgan, T. E., Xie, Z., Goldsmith, S., Yoshida, T., Lanzrein, A.-S., Stone, D., Rozovsky, I., Perry, G., Smith, M. A., & Finch, C. E. (1999) · Neuroscience

Neuroinflammation and Neurodegeneration MechanismsGenetics, Aging, and Longevity in Model Organisms

Cited by 195

Tau – an inhibitor of deacetylase HDAC6 function

Perez, M., Santa‐Maria, I., De Barreda, E. G., Zhu, X., Cuadros, R., Cabrero, J. R., Sanchez‐Madrid, F., Dawson, H. N., Vitek, M. P., Perry, G., et al. (2009) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsHistone Deacetylase Inhibitors Research

Cited by 182

Iron: The Redox-active Center of Oxidative Stress in Alzheimer Disease

Castellani, R. J., Moreira, P. I., Liu, G., Dobson, J., Perry, G., Smith, M. A., & Zhu, X. (2007) · Neurochemical Research

Alzheimer's disease research and treatmentsIron Metabolism and Disorders

Cited by 180