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Microglial P2X7receptor expression is accompanied by neuronal damage in the cerebral cortex of the APPswe/PS1dE9 mouse model of Alzheimer's disease

Lee, H. G., Won, S. M., Gwag, B. J., & Lee, Y. B. (2011) · Experimental & Molecular Medicine · doi:10.3858/emm.2011.43.1.001 · Cited by 118 · see citing works

Mechanisms of Altered Redox Regulation in Neurodegenerative Diseases—Focus on S-Glutathionylation

Liedhegner, E. S., Gao, X., & Mieyal, J. J. (2011) · Antioxidants and Redox Signaling · doi:10.1089/ars.2011.4119 · Cited by 116 · see citing works

Redox signaling in central neural regulation of cardiovascular function

Zimmerman, M. C., & Davisson, R. L. (2003) · Progress in Biophysics and Molecular Biology · doi:10.1016/j.pbiomolbio.2003.11.009 · Cited by 115 · see citing works

Ibuprofen attenuates oxidative damage through NOX2 inhibition in Alzheimer's disease

Wilkinson, B. L., Cramer, P. E., Varvel, N. H., Reed-Geaghan, E. G., Jiang, Q., Szabo, A., Herrup, K., Lamb, B. T., & Landreth, G. E. (2010) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2010.06.014 · Cited by 116 · see citing works

Metformin increases APP expression and processing via oxidative stress, mitochondrial dysfunction and NF-κB activation: Use of insulin to attenuate metformin's effect

Picone, P., Nuzzo, D., Caruana, L., Messina, E., Barera, A., Vasto, S., & Carlo, M. D. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2015.01.017 · Cited by 114 · see citing works

A Role for NOX NADPH Oxidases in Alzheimer's Disease and Other Types of Dementia?

Zekry, D., Epperson, T. K., & Krause, K. (2003) · IUBMB Life · doi:10.1080/1521654031000153049 · Cited by 112 · see citing works

Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer’s disease

Lassmann, H. (2011) · Journal of Neural Transmission · doi:10.1007/s00702-011-0607-8 · Cited by 112 · see citing works

Prostaglandin E2 receptor subtype 2 (EP2) regulates microglial activation and associated neurotoxicity induced by aggregated α-synuclein

Jin, J., Shie, F., Liu, J., Wang, Y., Davis, J., Schantz, A. M., Montine, K. S., Montine, T. J., & Zhang, J. (2007) · Journal of Neuroinflammation · doi:10.1186/1742-2094-4-2 · Cited by 112 · see citing works

Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway

Chuang, D. Y., Simonyi, Á., Kotzbauer, P. T., Gu, Z., & Sun, G. Y. (2015) · Journal of Neuroinflammation · doi:10.1186/s12974-015-0419-0 · Cited by 110 · see citing works

Novel isoforms of NADPH-oxidase in cerebral vascular control

Miller, A. A., Drummond, G. R., & Sobey, C. G. (2006) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2006.02.005 · Cited by 109 · see citing works

Oxidative stress, redox signalling and endothelial dysfunction in ageing‐related neurodegenerative diseases: a role of NADPH oxidase 2

Cahill‐Smith, S., & Li, J. (2014) · British Journal of Clinical Pharmacology · doi:10.1111/bcp.12357 · Cited by 106 · see citing works

Acute Hypertension Induces Oxidative Stress in Brain Tissues

Poulet, R., Gentile, M. T., Vecchione, C., Distaso, M., Aretini, A., Fratta, L., Russo, G., Echart, C., Maffei, A., Simoni, M. G. D., et al. (2005) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/sj.jcbfm.9600188 · Cited by 106 · see citing works

Vascular and metabolic dysfunction in Alzheimer’s disease: a review

Murray, I. V. J., Proza, J. F., Sohrabji, F., & Lawler, J. M. (2011) · Experimental Biology and Medicine · doi:10.1258/ebm.2011.010355 · Cited by 104 · see citing works

NOX Activity Is Increased in Mild Cognitive Impairment

Bruce‐Keller, A. J., Gupta, S., Parrino, T. E., Knight, A. G., Ebenezer, P. J., Weidner, A. M., LeVine, H., Keller, J. N., & Markesbery, W. R. (2009) · Antioxidants and Redox Signaling · doi:10.1089/ars.2009.2823 · Cited by 100 · see citing works

NADPH oxidases: redox regulation of cell homeostasis and disease

Kračun, D., Lopes, L. R., Cifuentes-Pagano, E., & Pagano, P. J. (2025) · Physiological Reviews · doi:10.1152/physrev.00034.2023 · Cited by 104 · see citing works

Photobiomodulation by low-power laser irradiation attenuates Aβ-induced cell apoptosis through the Akt/GSK3β/β-catenin pathway

Liang, J., Liu, L., & Xing, D. (2012) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2012.08.003 · Cited by 102 · see citing works

Fatty Acids: An Insight into the Pathogenesis of Neurodegenerative Diseases and Therapeutic Potential

Vesga-Jiménez, D. J., Martin, C., Barreto, G. E., Aristizábal-Pachón, A. F., Pinzón, A. M., & González, J. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052577 · Cited by 100 · see citing works

Cyclooxygenase and 5-lipoxygenase inhibitors protect against mononuclear phagocyte neurotoxicity

Klegeris, A., & MCGEER, P. (2002) · Neurobiology of Aging · doi:10.1016/s0197-4580(02)00021-0 · Cited by 96 · see citing works

Cognitive impairment in humanized APP×PS1 mice is linked to Aβ1–42 and NOX activation

Bruce-Keller, A. J., Gupta, S., Knight, A. G., Beckett, T. L., McMullen, J. M., Davis, P. R., Murphy, M. P., Van Eldik, L. J., St Clair, D., & Keller, J. N. (2011) · Neurobiology of Disease · doi:10.1016/j.nbd.2011.07.012 · Cited by 96 · see citing works

Reappraisal of metabolic dysfunction in neurodegeneration: Focus on mitochondrial function and calcium signaling

Jadiya, P., Garbincius, J. F., & Elrod, J. W. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01224-4 · Cited by 94 · see citing works

NOX2 As a Target for Drug Development: Indications, Possible Complications, and Progress

Diebold, B. A., Smith, S. M., Yang, L., & Lambeth, J. D. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.5862 · Cited by 96 · see citing works

Phosphatidylserine and phosphatidylcholine-containing liposomes inhibit amyloid β and interferon-γ-induced microglial activation

Hashioka, S., Han, Y.-H., Fujii, S., Kato, T. A., Monji, A., Utsumi, H., Sawada, M., Nakanishi, H., & Kanba, S. (2006) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2006.12.003 · Cited by 96 · see citing works

Alzheimer’s Disease and Cholesterol: The Fat Connection

Canevari, L., & Clark, J. B. (2006) · Neurochemical Research · doi:10.1007/s11064-006-9200-1 · Cited by 93 · see citing works

A key role for the microglial NADPH oxidase in APP-dependent killing of neurons

Qin, B., Cartier, L., Dubois‐Dauphin, M., Li, B., Serrander, L., & Krause, K. (2005) · Neurobiology of Aging · doi:10.1016/j.neurobiolaging.2005.09.036 · Cited by 95 · see citing works

Inducible nitric oxide synthase is key to peroxynitrite-mediated, LPS-induced protein radical formation in murine microglial BV2 cells

Kumar, A., Chen, S., Kadiiska, M. B., Hong, J., Zielonka, J., Kalyanaraman, B., & Mason, R. P. (2014) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2014.04.014 · Cited by 94 · see citing works

NADPH oxidase as a therapeutic target in Alzheimer's disease

Block, M. L. (2008) · BMC Neuroscience · doi:10.1186/1471-2202-9-s2-s8 · Cited by 202 · see citing works

The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer's disease.

Wilkinson, B. L., & Landreth, G. E. (2006) · Journal of Neuroinflammation · doi:10.1186/1742-2094-3-30 · Cited by 235 · see citing works

Oxidative Stress, Neuroinflammation, and NADPH Oxidase: Implications in the Pathogenesis and Treatment of Alzheimer’s Disease

Ganguly, U., Kaur, U., Chakrabarti, S. S., Sharma, P., Agrawal, B. K., Saso, L., & Chakrabarti, S. (2021) · Oxidative Medicine and Cellular Longevity · doi:10.1155/2021/7086512 · Cited by 150 · see citing works

Oligomeric Aβ-Induced Microglial Activation is Possibly Mediated by NADPH Oxidase

Li, J., Yang, J., Yao, X., Xue, X., Zhang, Q. C., Wang, X. X., Ding, L., & Wu, C. F. (2012) · Neurochemical Research · doi:10.1007/s11064-012-0939-2 · Cited by 27 · see citing works

β-Amyloid Activates the O⨪2 Forming NADPH Oxidase in Microglia, Monocytes, and Neutrophils

Della Bianca, V., Dusi, S., Bianchini, E., Dal Prà, I., & Rossi, F. (1999) · Journal of Biological Chemistry · doi:10.1074/jbc.274.22.15493 · Cited by 324 · see citing works