Riggs, Arthur D.

Expression in Escherichia coli of chemically synthesized genes for human insulin.

Goeddel, D. V., Kleid, D. G., Bolivar, F., Heyneker, H. L., Yansura, D. G., Crea, R., Hirose, T., Kraszewski, A., Itakura, K., & Riggs, A. D. (1979) · Proceedings of the National Academy of Sciences

Protein purification and stabilityBacterial Genetics and Biotechnology

Cited by 869

The general affinity of lac repressor for E. coli DNA: Implications for gene regulation in procaryotes and eucaryotes

Lin, S.-Y., & Riggs, A. D. (1975) · Cell

Diffusion and Search DynamicsBacterial Genetics and Biotechnology

Cited by 338

DNA lesions induced by UV A1 and B radiation in human cells: Comparative analyses in the overall genome and in the p53 tumor suppressor gene

Besaratinia, A., Synold, T. W., Chen, H.-H., Chang, C., Xi, B., Riggs, A. D., & Pfeifer, G. P. (2005) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsCarcinogens and Genotoxicity Assessment

Cited by 156

DNA methylation and late replication probably aid cell memory, and type I DNA reeling could aid chromosome folding and enhancer function

Riggs, A. D. (1990) · Philosophical Transactions of the Royal Society of London. B, Biological Sciences

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 126

Epigenetic Silencing May Aid Evolution by Gene Duplication

Rodin, S. N., & Riggs, A. D. (2003) · Journal of Molecular Evolution

Chromosomal and Genetic VariationsEvolution and Genetic Dynamics

Cited by 120

Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel

Jin, L., Feng, T., Shih, H. P., Zerda, R., Luo, A., Hsu, J., Mahdavi, A., Sander, M., Tirrell, D. A., Riggs, A. D., et al. (2013) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 108

Intestinal AMPK modulation of microbiota mediates crosstalk with brown fat to control thermogenesis

Zhang, E., Jin, L., Wang, Y., Tu, J., Zheng, R., Ding, L., Fang, Z., Fan, M., Al-Abdullah, I., Natarajan, R., et al. (2022) · Nature Communications

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 76

SR4 Uncouples Mitochondrial Oxidative Phosphorylation, Modulates AMP-dependent Kinase (AMPK)-Mammalian Target of Rapamycin (mTOR) Signaling, and Inhibits Proliferation of HepG2 Hepatocarcinoma Cells

Figarola, J. L., Singhal, J., Tompkins, J. D., Rogers, G. W., Warden, C., Horne, D., Riggs, A. D., Awasthi, S., & Singhal, S. S. (2015) · Journal of Biological Chemistry

Mitochondrial Function and PathologyMetabolism, Diabetes, and Cancer

Cited by 41

Rlip depletion prevents spontaneous neoplasia in TP53 null mice

Awasthi, S., Tompkins, J., Singhal, J., Riggs, A. D., Yadav, S., Wu, X., Singh, S., Warden, C., Liu, Z., Wang, J., et al. (2018) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 33

Cells with surface expression of CD133highCD71low are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas

Jin, L., Gao, D., Feng, T., Tremblay, J. R., Ghazalli, N., Luo, A., Rawson, J., Quijano, J. C., Chai, J., Wedeken, L., et al. (2016) · Stem Cell Research

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 32

Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro

Ghazalli, N., Mahdavi, A., Feng, T., Jin, L., Kozlowski, M. T., Hsu, J., Riggs, A. D., Tirrell, D. A., & Ku, H. T. (2015) · Stem Cells and Development

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 17

Colony-Forming Progenitor Cells in the Postnatal Mouse Liver and Pancreas Give Rise to Morphologically Distinct Insulin-Expressing Colonies in 3D Cultures

Jin, L., Feng, T., Chai, J., Ghazalli, N., Gao, D., Zerda, R., Li, Z., Hsu, J., Mahdavi, A., Tirrell, D. A., et al. (2014) · The Review of Diabetic Studies

Pancreatic function and diabetesPluripotent Stem Cells Research

Cited by 9