Linkermann, Andreas

Ferroptosis: A Regulated Cell Death Nexus Linking Metabolism, Redox Biology, and Disease

Stockwell, B. R., Friedmann Angeli, J. P., Bayir, H., Bush, A. I., Conrad, M., Dixon, S. J., Fulda, S., Gascón, S., Hatzios, S. K., Kagan, V. E., et al. (2017) · Cell

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 7,695

Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

Galluzzi, L., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Agostinis, P., Alnemri, E. S., Altucci, L., Amelio, I., Andrews, D. W., et al. (2018) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 6,680

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition).

Klionsky, D. J., Abdelmohsen, K., Abe, A., Abedin, M. J., Abeliovich, H., Acevedo Arozena, A., Adachi, H., Adams, C. M., Adams, P. D., Adeli, K., et al. (2016) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 5,894

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

Berghe, T. V., Linkermann, A., Jouan-Lanhouet, S., Walczak, H., & Vandenabeele, P. (2014) · Nature Reviews Molecular Cell Biology

Cell death mechanisms and regulationFerroptosis and cancer prognosis

Cited by 1,735

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

Skouta, R., Dixon, S. J., Wang, J., Dunn, D. E., Orman, M., Shimada, K., Rosenberg, P. A., Lo, D. C., Weinberg, J. M., Linkermann, A., et al. (2014) · Journal of the American Chemical Society

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 1,146

Synchronized renal tubular cell death involves ferroptosis

Linkermann, A., Skouta, R., Himmerkus, N., Mulay, S. R., Dewitz, C., De Zen, F., Prokai, A., Zuchtriegel, G., Krombach, F., Welz, P.-S., et al. (2014) · Proceedings of the National Academy of Sciences

Ferroptosis and cancer prognosisCell death mechanisms and regulation

Cited by 1,126

Necroptosis

Linkermann, A., & Green, D. R. (2014) · New England Journal of Medicine

Cell death mechanisms and regulationFerroptosis and cancer prognosis

Cited by 1,103

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

Galluzzi, L., Bravo-San Pedro, J. M., Vitale, I., Aaronson, S. A., Abrams, J. M., Adam, D., Alnemri, E. S., Altucci, L., Andrews, D., Annicchiarico-Petruzzelli, M., et al. (2015) · Cell Death & Differentiation

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 1,002

ESCRT-III Acts Downstream of MLKL to Regulate Necroptotic Cell Death and Its Consequences

Gong, Y.-N., Guy, C., Olauson, H., Becker, J. U., Yang, M., Fitzgerald, P., Linkermann, A., & Green, D. R. (2017) · Cell

Cell death mechanisms and regulationCellular transport and secretion

Cited by 689

Ferroptosis, but Not Necroptosis, Is Important in Nephrotoxic Folic Acid–Induced AKI

Martin-Sanchez, D., Ruiz-Andres, O., Poveda, J., Carrasco, S., Cannata-Ortiz, P., Sanchez-Niño, M. D., Ruiz Ortega, M., Egido, J., Linkermann, A., Ortiz, A., et al. (2017) · Journal of the American Society of Nephrology

Acute Kidney Injury ResearchFerroptosis and cancer prognosis

Cited by 564

Regulated cell death and inflammation: an auto-amplification loop causes organ failure

Linkermann, A., Stockwell, B. R., Krautwald, S., & Anders, H.-J. (2014) · Nature Reviews Immunology

Cell death mechanisms and regulationImmune Response and Inflammation

Cited by 522

RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

Martinez, J., Cunha, L. D., Park, S., Yang, M., Lu, Q., Orchard, R., Li, Q.-Z., Yan, M., Janke, L., Guy, C., et al. (2016) · Nature

Systemic Lupus Erythematosus ResearchAutophagy in Disease and Therapy

Cited by 381

Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

Tait, S. W. G., Oberst, A., Quarato, G., Milasta, S., Haller, M., Wang, R., Karvela, M., Ichim, G., Yatim, N., Albert, M. L., et al. (2013) · Cell Reports

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 303

TBK1 and IKKε prevent TNF-induced cell death by RIPK1 phosphorylation

Lafont, E., Draber, P., Rieser, E., Reichert, M., Kupka, S., de Miguel, D., Draberova, H., von Mässenhausen, A., Bhamra, A., Henderson, S., et al. (2018) · Nature Cell Biology

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 283

Molecular mechanisms of regulated necrosis

Galluzzi, L., Kepp, O., Krautwald, S., Kroemer, G., & Linkermann, A. (2014) · Seminars in Cell & Developmental Biology

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 258

Targeting ferroptosis protects against experimental (multi)organ dysfunction and death

Van Coillie, S., Van San, E., Goetschalckx, I., Wiernicki, B., Mukhopadhyay, B., Tonnus, W., Choi, S. M., Roelandt, R., Dumitrascu, C., Lamberts, L., et al. (2022) · Nature Communications

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 186

Targeting ferroptosis protects against multiorgan dysfunction and death.

VandenBerghe, T., Coillie, S. V., Goetschalckx, I., Wiernicki, B., Mukhopadhyay, B., Tonnus, W., San, E. V., Choi, S. M., Roelandt, R., Dumitrascu, C., et al. (2021) · Nature Communications

Ferroptosis and cancer prognosisIron Metabolism and Disorders

Cited by 186

Ferroptosis-inducing agents compromise in vitro human islet viability and function

Bruni, A., Pepper, A. R., Pawlick, R. L., Gala-Lopez, B., Gamble, A. F., Kin, T., Seeberger, K., Korbutt, G. S., Bornstein, S. R., Linkermann, A., et al. (2018) · Cell Death & Disease

Pancreatic function and diabetesFerroptosis and cancer prognosis

Cited by 180

The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis

Günther, C., He, G.-W., Kremer, A. E., Murphy, J. M., Petrie, E. J., Amann, K., Vandenabeele, P., Linkermann, A., Poremba, C., Schleicher, U., et al. (2016) · Journal of Clinical Investigation

Cell death mechanisms and regulationLiver Diseases and Immunity

Cited by 157

An Overview of Pathways of Regulated Necrosis in Acute Kidney Injury

Kers, J., Leemans, J. C., & Linkermann, A. (2016) · Seminars in Nephrology

Acute Kidney Injury ResearchCell death mechanisms and regulation

Cited by 80

Catch me if you can: targeting the mitochondrial permeability transition pore in myocardial infarction

Linkermann, A., Konstantinidis, K., & Kitsis, R. N. (2016) · Cell Death & Differentiation

Cardiac Ischemia and ReperfusionMitochondrial Function and Pathology

Cited by 36