Watkins, Linda R.

Nitroxidative signaling mechanisms in pathological pain

Grace, P. M., Gaudet, A. D., Staikopoulos, V., Maier, S. F., Hutchinson, M. R., Salvemini, D., & Watkins, L. R. (2016) · Trends in Neurosciences

Pain Mechanisms and TreatmentsRedox biology and oxidative stress

Cited by 128

Effect of chronic delivery of the Toll-like receptor 4 antagonist (+)-naltrexone on incubation of heroin craving

Theberge, F. R., Li, X., Kambhampati, S., Pickens, C. L., St. Laurent, R., Bossert, J. M., Baumann, M. H., Hutchinson, M. R., Rice, K. C., Watkins, L. R., et al. (2013) · Biological Psychiatry

Neurotransmitter Receptor Influence on BehaviorNeuropeptides and Animal Physiology

Cited by 119

Stress- and Glucocorticoid-Induced Priming of Neuroinflammatory Responses: Potential Mechanisms of Stress-Induced Vulnerability to Drugs of Abuse

Frank, M. G., Watkins, L. R., & Maier, S. F. (2011) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsTryptophan and brain disorders

Cited by 116

Prior stressor exposure primes the HPA axis

Johnson, J. D., O'Connor, K. A., Deak, T., Spencer, R. L., Watkins, L. R., & Maier, S. F. (2002) · Psychoneuroendocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 110

The role of prior stressor controllability and the dorsal raphé nucleus in sucrose preference and social exploration

Christianson, J. P., Paul, E. D., Irani, M., Thompson, B. M., Kubala, K. H., Yirmiya, R., Watkins, L. R., & Maier, S. F. (2008) · Behavioural Brain Research

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 107

Selective activation of dorsal raphe nucleus‐projecting neurons in the ventral medial prefrontal cortex by controllable stress

Baratta, M. V., Zarza, C. M., Gomez, D. M., Campeau, S., Watkins, L. R., & Maier, S. F. (2009) · European Journal of Neuroscience

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 106

Safety Signals Mitigate the Consequences of Uncontrollable Stress Via a Circuit Involving the Sensory Insular Cortex and Bed Nucleus of the Stria Terminalis

Christianson, J. P., Jennings, J. H., Ragole, T., Flyer, J. G. N., Benison, A. M., Barth, D. S., Watkins, L. R., & Maier, S. F. (2011) · Biological Psychiatry

Memory and Neural MechanismsStress Responses and Cortisol

Cited by 104

Behavioral control over shock blocks behavioral and neurochemical effects of later social defeat

Amat, J., Aleksejev, R. M., Paul, E., Watkins, L. R., & Maier, S. F. (2010) · Neuroscience

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 101

Uncontrollable, But Not Controllable, Stress Desensitizes 5-HT1AReceptors in the Dorsal Raphe Nucleus

Rozeske, R. R., Evans, A. K., Frank, M. G., Watkins, L. R., Lowry, C. A., & Maier, S. F. (2011) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 100

The Sensory Insular Cortex Mediates the Stress-Buffering Effects of Safety Signals But Not Behavioral Control

Christianson, J. P., Benison, A. M., Jennings, J., Sandsmark, E. K., Amat, J., Kaufman, R. D., Baratta, M. V., Paul, E. D., Campeau, S., Watkins, L. R., et al. (2008) · The Journal of Neuroscience

Memory and Neural MechanismsStress Responses and Cortisol

Cited by 97

Blocking toll-like receptor 2 and 4 signaling during a stressor prevents stress-induced priming of neuroinflammatory responses to a subsequent immune challenge

Weber, M. D., Frank, M. G., Sobesky, J. L., Watkins, L. R., & Maier, S. F. (2013) · Brain, Behavior, and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 93

Differential effects of neonatal handling on early life infection-induced alterations in cognition in adulthood

Bilbo, S. D., Newsum, N. J., Sprunger, D. B., Watkins, L. R., Rudy, J. W., & Maier, S. F. (2007) · Brain Behavior and Immunity

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 88

Antiadhesive Effects of GRN163L—An Oligonucleotide N3′→P5′ Thio-Phosphoramidate Targeting Telomerase

Jackson, S. R., Zhu, C.-H., Paulson, V., Watkins, L., Dikmen, Z. G., Gryaznov, S. M., Wright, W. E., & Shay, J. W. (2007) · Cancer Research

Telomeres, Telomerase, and SenescenceRNA Interference and Gene Delivery

Cited by 72

Greater glucocorticoid receptor activation in hippocampus of aged rats sensitizes microglia

Barrientos, R. M., Thompson, V. M., Kitt, M. M., Amat, J., Hale, M. W., Frank, M. G., Crysdale, N. Y., Stamper, C. E., Hennessey, P. A., Watkins, L. R., et al. (2015) · Neurobiology of Aging

Neuroinflammation and Neurodegeneration MechanismsStress Responses and Cortisol

Cited by 70

Inescapable shock induces resistance to the effects of dexamethasone

O’Connor, K. A., Johnson, J. D., Hammack, S. E., Brooks, L. M., Spencer, R. L., Watkins, L. R., & Maier, S. F. (2003) · Psychoneuroendocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 69

Dynamic Regulation of Proinflammatory Cytokines

Watkins, L. R., Nguyen, K. T., Lee, J. E., & Maier, S. F. (1999) · Advances in Experimental Medicine and Biology

Tryptophan and brain disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 67

Role of the ventral medial prefrontal cortex in mediating behavioral control-induced reduction of later conditioned fear

Baratta, M. V., Lucero, T. R., Amat, J., Watkins, L. R., & Maier, S. F. (2008) · Learning & Memory

Memory and Neural MechanismsNeurotransmitter Receptor Influence on Behavior

Cited by 58

Control over a stressor involves the posterior dorsal striatum and the act/outcome circuit

Amat, J., Christianson, J. P., Aleksejev, R. M., Kim, J., Richeson, K. R., Watkins, L. R., & Maier, S. F. (2014) · European Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorMemory and Neural Mechanisms

Cited by 50

Surgical and pharmacological suppression of glucocorticoids prevents the enhancement of morphine conditioned place preference by uncontrollable stress in rats

Der-Avakian, A., Will, M. J., Bland, S. T., Deak, T., Nguyen, K. T., Schmid, M. J., Spencer, R. L., Watkins, L. R., & Maier, S. F. (2005) · Psychopharmacology

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 47

Stress-Induced Sensitization of the Hypothalamic-Pituitary Adrenal Axis Is Associated with Alterations of Hypothalamic and Pituitary Gene Expression

O’Connor, K. A., Ginsberg, A. B., Maksimova, E., Wieseler Frank, J. L., Johnson, J. D., Spencer, R. L., Campeau, S., Watkins, L. R., & Maier, S. F. (2004) · Neuroendocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 41

Blockade of alpha1 adrenoreceptors in the dorsal raphe nucleus prevents enhanced conditioned fear and impaired escape performance following uncontrollable stressor exposure in rats

Grahn, R. E., Hammack, S. E., Will, M. J., O'Connor, K. A., Deak, T., Sparks, P. D., Watkins, L. R., & Maier, S. F. (2002) · Behavioural Brain Research

Stress Responses and CortisolNeurotransmitter Receptor Influence on Behavior

Cited by 40

Electrolytic lesions and pharmacological inhibition of the dorsal raphe nucleus prevent stressor potentiation of morphine conditioned place preference in rats

Will, M. J., Der-Avakian, A., Bland, S. T., Grahn, R. E., Hammack, S. E., Sparks, P. D., Pepin, J. L., Watkins, L. R., & Maier, S. F. (2004) · Psychopharmacology

Neurotransmitter Receptor Influence on BehaviorStress Responses and Cortisol

Cited by 40

Learned stressor resistance requires extracellular signal-regulated kinase in the prefrontal cortex

Christianson, J. P., Flyer-Adams, J. G., Drugan, R. C., Amat, J., Daut, R. A., Foilb, A. R., Watkins, L. R., & Maier, S. F. (2014) · Frontiers in Behavioral Neuroscience

Stress Responses and CortisolMemory and Neural Mechanisms

Cited by 39

Immunogenicity of intrathecal plasmid gene delivery: cytokine release and effects on transgene expression

Hughes, T. S., Langer, S. J., Virtanen, S. I., Chavez, R. A., Watkins, L. R., Milligan, E. D., & Leinwand, L. A. (2009) · The Journal of Gene Medicine

RNA Interference and Gene DeliveryVirus-based gene therapy research

Cited by 28