Coussens, Lisa M.

Inflammation and cancer

Coussens, L. M., & Werb, Z. (2002) · Nature

Immune cells in cancerInflammatory mediators and NSAID effects

Cited by 15,111

Understanding the tumor immune microenvironment (TIME) for effective therapy

Binnewies, M., Roberts, E. W., Kersten, K., Chan, V., Fearon, D. F., Merad, M., Coussens, L. M., Gabrilovich, D. I., Ostrand-Rosenberg, S., Hedrick, C. C., et al. (2018) · Nature Medicine

Cancer Immunotherapy and BiomarkersImmune cells in cancer

Cited by 6,145

Gut microbiome modulates response to anti-PD-1 immunotherapy in melanoma patients

Gopalakrishnan, V., Spencer, C. N., Nezi, L., Reuben, A., Andrews, M. C., Karpinets, T. V., Prieto, P. A., Vicente, D., Hoffman, K., Wei, S. C., et al. (2018) · Science

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 4,812

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

Hanahan, D., & Coussens, L. M. (2012) · Cancer Cell

Cancer Cells and MetastasisImmune cells in cancer

Cited by 4,632

Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations

Coussens, L. M., Fingleton, B., & Matrisian, L. M. (2002) · Science

Protease and Inhibitor MechanismsTGF-β signaling in diseases

Cited by 2,761

Macrophages and metabolism in the tumor microenvironment

Vitale, I., Manic, G., Coussens, L. M., Kroemer, G., & Galluzzi, L. (2019) · Cell Metabolism

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 1,837

Leukocyte Complexity Predicts Breast Cancer Survival and Functionally Regulates Response to Chemotherapy

DeNardo, D. G., Brennan, D. J., Rexhepaj, E., Ruffell, B., Shiao, S. L., Madden, S. F., Gallagher, W. M., Wadhwani, N., Keil, S. D., Junaid, S. A., et al. (2011) · Cancer Discovery

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 1,715

Iron oxide nanoparticles inhibit tumour growth by inducing pro-inflammatory macrophage polarization in tumour tissues

Zanganeh, S., Hutter, G., Spitler, R., Lenkov, O., Mahmoudi, M., Shaw, A., Pajarinen, J. S., Nejadnik, H., Goodman, S., Moseley, M., et al. (2016) · Nature Nanotechnology

Immune cells in cancerNanoplatforms for cancer theranostics

Cited by 1,647

Macrophages and Therapeutic Resistance in Cancer

Ruffell, B., & Coussens, L. M. (2015) · Cancer Cell

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 1,474

Early Detection of Cancer

Crosby, D., Bhatia, S., Brindle, K. M., Coussens, L. M., Dive, C., Emberton, M., Esener, S., Fitzgerald, R. C., Gambhir, S. S., Kuhn, P., et al. (2022) · Science

Global Cancer Incidence and ScreeningCancer Genomics and Diagnostics

Cited by 1,379

MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

Coussens, L. M., Tinkle, C. L., Hanahan, D., & Werb, Z. (2000) · Cell

Protease and Inhibitor MechanismsImmune cells in cancer

Cited by 1,306

Macrophage IL-10 blocks CD8+ T cell-dependent responses to chemotherapy by suppressing IL-12 expression in intratumoral dendritic cells

Ruffell, B., Chang-Strachan, D., Chan, V., Rosenbusch, A., Ho, C. M. T., Pryer, N., Daniel, D., Hwang, E. S., Rugo, H. S., & Coussens, L. M. (2014) · Cancer Cell

Immune cells in cancerCancer Immunotherapy and Biomarkers

Cited by 1,008

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

Coussens, L. M., Raymond, W. W., Bergers, G., Laig-Webster, M., Behrendtsen, O., Werb, Z., Caughey, G. H., & Hanahan, D. (1999) · Genes & Development

Angiogenesis and VEGF in CancerMast cells and histamine

Cited by 946

The Basis of Oncoimmunology

Palucka, A. K., & Coussens, L. M. (2016) · Cell

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 843

Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression

Doedens, A. L., Stockmann, C., Rubinstein, M. P., Liao, D., Zhang, N., DeNardo, D. G., Coussens, L. M., Karin, M., Goldrath, A. W., & Johnson, R. S. (2010) · Cancer Research

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 652

Collagen-based cell migration models in vitro and in vivo

Wolf, K., Alexander, S., Schacht, V., Coussens, L. M., von Andrian, U. H., van Rheenen, J., Deryugina, E., & Friedl, P. (2009) · Seminars in Cell & Developmental Biology

Cellular Mechanics and InteractionsCollagen: Extraction and Characterization

Cited by 637

Tumor Microenvironment Complexity: Emerging Roles in Cancer Therapy

Swartz, M. A., Iida, N., Roberts, E. W., Sangaletti, S., Wong, M. H., Yull, F. E., Coussens, L. M., & DeClerck, Y. A. (2012) · Cancer Research

Cancer Cells and MetastasisCancer Immunotherapy and Biomarkers

Cited by 542

TIM-3 regulates CD103+ dendritic cell function and response to chemotherapy in breast cancer

de Mingo Pulido, Á., Gardner, A., Hiebler, S., Soliman, H., Rugo, H. S., Krummel, M. F., Coussens, L. M., & Ruffell, B. (2018) · Cancer Cell

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 388

Neoadjuvant Selicrelumab, an agonist CD40 antibody, induces changes in the tumor microenvironment in patients with resectable pancreatic cancer

Byrne, K. T., Betts, C. B., Mick, R., Sivagnanam, S., Bajor, D. L., Laheru, D. A., Chiorean, E. G., O'Hara, M. H., Liudahl, S. M., Newcomb, C., et al. (2021) · Clinical Cancer Research

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 199

Leukocyte heterogeneity in pancreatic ductal adenocarcinoma: phenotypic and spatial features associated with clinical outcome

Liudahl, S. M., Betts, C. B., Sivagnanam, S., Morales-Oyarvide, V., da Silva, A., Yuan, C., Hwang, S., Grossblatt-Wait, A., Leis, K. R., Larson, W., et al. (2021) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchCancer Immunotherapy and Biomarkers

Cited by 164

Poor Response to Neoadjuvant Chemotherapy Correlates with Mast Cell Infiltration in Inflammatory Breast Cancer

Reddy, S. M., Reuben, A., Barua, S., Jiang, H., Zhang, S., Wang, L., Gopalakrishnan, V., Hudgens, C. W., Tetzlaff, M. T., Reuben, J. M., et al. (2019) · Cancer Immunology Research

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 106