Xu, Aimin

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

Xu, A., Wang, Y., Keshaw, H., Xu, L. Y., Lam, K. S. L., & Cooper, G. J. S. (2003) · Journal of Clinical Investigation

Liver Disease Diagnosis and TreatmentAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,298

Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans

Zhang, X., Yeung, D. C. Y., Karpisek, M., Stejskal, D., Zhou, Z.-G., Liu, F., Wong, R. L. C., Chow, W.-S., Tso, A. W. K., Lam, K. S. L., et al. (2008) · Diabetes

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 908

Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe −/− Mice

Li, J., Lin, S., Vanhoutte, P. M., Woo, C. W., & Xu, A. (2016) · Circulation

Gut microbiota and healthAtherosclerosis and Cardiovascular Diseases

Cited by 775

Adiponectin mediates the metabolic effects of FGF21 on glucose homeostasis and insulin sensitivity in mice

Lin, Z., Tian, H., Lam, K. S. L., Lin, S., Hoo, R. C. L., Konishi, M., Itoh, N., Wang, Y., Bornstein, S. R., Xu, A., et al. (2013) · Cell Metabolism

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 691

The therapeutic potential of FGF21 in metabolic diseases: from bench to clinic

Geng, L., Lam, K. S. L., & Xu, A. (2020) · Nature Reviews Endocrinology

Fibroblast Growth Factor ResearchLiver Disease Diagnosis and Treatment

Cited by 607

Lipocalin-2 Is an Inflammatory Marker Closely Associated with Obesity, Insulin Resistance, and Hyperglycemia in Humans

Wang, Y., Lam, K. S. L., Kraegen, E. W., Sweeney, G., Zhang, J., Tso, A. W., Chow, W.-S., Wat, N. M., Xu, J. Y., Hoo, R. L., et al. (2007) · Clinical Chemistry

Adipokines, Inflammation, and Metabolic DiseasesDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 578

Metagenomic sequencing of the human gut microbiome before and after bariatric surgery in obese patients with type 2 diabetes: correlation with inflammatory and metabolic parameters

Graessler, J., Qin, Y., Zhong, H., Zhang, J., Licinio, J., Wong, M.-L., Xu, A., Chavakis, T., Bornstein, A. B., Ehrhart-Bornstein, M., et al. (2013) · The Pharmacogenomics Journal

Gut microbiota and healthBariatric Surgery and Outcomes

Cited by 428

Gut Microbiome Fermentation Determines the Efficacy of Exercise for Diabetes Prevention

Liu, Y., Wang, Y., Ni, Y., Cheung, C. K. Y., Lam, K. S. L., Wang, Y., Xia, Z., Ye, D., Guo, J., Tse, M. A., et al. (2020) · Cell Metabolism

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 405

Physical exercise-induced hippocampal neurogenesis and antidepressant effects are mediated by the adipocyte hormone adiponectin

Yau, S. Y., Li, A., Hoo, R. L. C., Ching, Y. P., Christie, B. R., Lee, T. M. C., Xu, A., & So, K.-F. (2014) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsRegulation of Appetite and Obesity

Cited by 326

FGF21 maintains glucose homeostasis by mediating the cross talk between liver and brain during prolonged fasting

Liang, Q., Zhong, L., Zhang, J., Wang, Y., Bornstein, S. R., Triggle, C. R., Ding, H., Lam, K. S. L., & Xu, A. (2014) · Diabetes

Fibroblast Growth Factor ResearchRegulation of Appetite and Obesity

Cited by 299

Hypoxia dysregulates the production of adiponectin and plasminogen activator inhibitor-1 independent of reactive oxygen species in adipocytes

Chen, B., Lam, K. S. L., Wang, Y., Wu, D., Lam, M. C., Shen, J., Wong, L., Hoo, R. L. C., Zhang, J., & Xu, A. (2006) · Biochemical and Biophysical Research Communications

Adipokines, Inflammation, and Metabolic DiseasesPeroxisome Proliferator-Activated Receptors

Cited by 238

Toll-like receptor-4 mediates obesity-induced non-alcoholic steatohepatitis through activation of X-box binding protein-1 in mice

Ye, D., Li, F. Y. L., Lam, K. S. L., Li, H., Jia, W., Wang, Y., Man, K., Lo, C. M., Li, X., & Xu, A. (2012) · Gut

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 206

Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1α-mediated antioxidant capacity in mice

Ye, D., Wang, Y., Li, H., Jia, W., Man, K., Lo, C. M., Wang, Y., Lam, K. S. L., & Xu, A. (2014) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionFibroblast Growth Factor Research

Cited by 184

Dipeptidyl Peptidase 4 Inhibitor Sitagliptin Protects Endothelial Function in Hypertension Through a Glucagon–Like Peptide 1–Dependent Mechanism

Liu, L., Liu, J., Wong, W. T., Tian, X. Y., Lau, C. W., Wang, Y.-X., Xu, G., Pu, Y., Zhu, Z., Xu, A., et al. (2012) · Hypertension

Diabetes Treatment and ManagementNitric Oxide and Endothelin Effects

Cited by 179

Fibroblast growth factor 21 increases insulin sensitivity through specific expansion of subcutaneous fat

Li, H., Wu, G., Fang, Q., Zhang, M., Hui, X., Sheng, B., Wu, L., Bao, Y., Li, P., Xu, A., et al. (2018) · Nature Communications

Fibroblast Growth Factor ResearchAdipokines, Inflammation, and Metabolic Diseases

Cited by 178

Adiponectin is expressed by skeletal muscle fibers and influences muscle phenotype and function

Krause, M. P., Liu, Y., Vu, V., Chan, L., Xu, A., Riddell, M. C., Sweeney, G., & Hawke, T. J. (2008) · American Journal of Physiology-Cell Physiology

Muscle Physiology and DisordersAdipose Tissue and Metabolism

Cited by 168

Risk assessment with gut microbiome and metabolite markers in NAFLD development

Leung, H., Long, X., Ni, Y., Qian, L., Nychas, E., Siliceo, S. L., Pohl, D., Hanhineva, K., Liu, Y., Xu, A., et al. (2022) · Science Translational Medicine

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 152

The FGF21-CCL11 Axis Mediates Beiging of White Adipose Tissues by Coupling Sympathetic Nervous System to Type 2 Immunity

Huang, Z., Zhong, L., Lee, J. T. H., Zhang, J., Wu, D., Geng, L., Wang, Y., Wong, C.-M., & Xu, A. (2017) · Cell Metabolism

Adipose Tissue and MetabolismFibroblast Growth Factor Research

Cited by 147

Major urinary protein-1 increases energy expenditure and improves glucose intolerance through enhancing mitochondrial function in skeletal muscle of diabetic mice

Hui, X., Zhu, W., Wang, Y., Lam, K. S. L., Zhang, J., Wu, D., Kraegen, E. W., Li, Y., & Xu, A. (2009) · Journal of Biological Chemistry

Adipose Tissue and MetabolismMetabolism, Diabetes, and Cancer

Cited by 130

Adipose Tissue-specific Inhibition of Hypoxia-inducible Factor 1α Induces Obesity and Glucose Intolerance by Impeding Energy Expenditure in Mice*

Zhang, X., Lam, K. S. L., Ye, H., Chung, S. K., Zhou, M., Wang, Y., & Xu, A. (2010) · Journal of Biological Chemistry

Adipose Tissue and MetabolismAdipokines, Inflammation, and Metabolic Diseases

Cited by 112

Adiponectin: Protection of the endothelium

Lam, K. S. L., & Xu, A. (2005) · Current Diabetes Reports

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 94

Fibroblast growth factor-based pharmacotherapies for the treatment of obesity-related metabolic complications

Jin, L., Yang, R., Geng, L., & Xu, A. (2023) · Annual Review of Pharmacology and Toxicology

Fibroblast Growth Factor ResearchLiver Disease Diagnosis and Treatment

Cited by 71

Carnitine palmitoyltransferase 1A prevents fatty acid-induced adipocyte dysfunction through suppression of c-Jun N-terminal kinase

Gao, X., Li, K., Hui, X., Kong, X., Sweeney, G., Wang, Y., Xu, A., Teng, M., Liu, P., & Wu, D. (2011) · Biochemical Journal

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 68

Sequential algorithm to stratify liver fibrosis risk in overweight/obese metabolic dysfunction-associated fatty liver disease

Lee, C.-H., Lui, D. T.-W., Li, R. H.-W., Yuen, M. M.-A., Fong, C. H.-Y., Leung, A. P.-W., Chu, J. C.-M., Mak, L. L.-Y., Lam, T.-H., Woo, J., et al. (2023) · Frontiers in Endocrinology

Liver Disease Diagnosis and TreatmentDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 5