Larbi, Anis

Bystander CD8+ T cells are abundant and phenotypically distinct in human tumour infiltrates

Simoni, Y., Becht, E., Fehlings, M., Loh, C. Y., Koo, S.-L., Teng, K. W. W., Yeong, J. P. S., Nahar, R., Zhang, T., Kared, H., et al. (2018) · Nature

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 1,370

Immunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?

Fulop, T., Larbi, A., Dupuis, G., Le Page, A., Frost, E. H., Cohen, A. A., Witkowski, J. M., & Franceschi, C. (2018) · Frontiers in Immunology

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 1,364

C-Myb+ Erythro-Myeloid Progenitor-Derived Fetal Monocytes Give Rise to Adult Tissue-Resident Macrophages

Hoeffel, G., Chen, J., Lavin, Y., Low, D., Almeida, F. F., See, P., Beaudin, A. E., Lum, J., Low, I., Forsberg, E. C., et al. (2015) · Immunity

Hematopoietic Stem Cell TransplantationImmune cells in cancer

Cited by 1,135

Two distinct interstitial macrophage populations coexist across tissues in specific subtissular niches

Chakarov, S., Lim, H. Y., Tan, L., Lim, S. Y., See, P., Lum, J., Zhang, X.-M., Foo, S., Nakamizo, S., Duan, K., et al. (2019) · Science

Immune cells in cancerPhagocytosis and Immune Regulation

Cited by 1,114

RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types

Monaco, G., Lee, B., Xu, W., Mustafah, S., Hwang, Y. Y., Carré, C., Burdin, N., Visan, L., Ceccarelli, M., Poidinger, M., et al. (2019) · Cell Reports

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 958

Microbiome Influences Prenatal and Adult Microglia in a Sex-Specific Manner

Thion, M. S., Low, D., Silvin, A., Chen, J., Grisel, P., Schulte-Schrepping, J., Blecher, R., Ulas, T., Squarzoni, P., Hoeffel, G., et al. (2018) · Cell

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 779

Immunology of aging: the birth of inflammaging

Fulop, T., Larbi, A., Pawelec, G., Khalil, A., Cohen, A. A., Hirokawa, K., Witkowski, J. M., & Franceschi, C. (2021) · Clinical Reviews in Allergy & Immunology

Genetics, Aging, and Longevity in Model OrganismsImmune Response and Inflammation

Cited by 464

Aging of the immune system: Focus on inflammation and vaccination

Pinti, M., Appay, V., Campisi, J., Frasca, D., Fülöp, T., Sauce, D., Larbi, A., Weinberger, B., & Cossarizza, A. (2016) · European Journal of Immunology

Immune responses and vaccinationsImmune Response and Inflammation

Cited by 439

From “truly naïve” to “exhausted senescent” T cells: When markers predict functionality

Larbi, A., & Fulop, T. (2014) · Cytometry Part A

T-cell and B-cell ImmunologyHIV Research and Treatment

Cited by 359

Human T Cell Aging and the Impact of Persistent Viral Infections

Fülöp, T., Larbi, A., & Pawelec, G. (2013) · Frontiers in Immunology

T-cell and B-cell ImmunologyTelomeres, Telomerase, and Senescence

Cited by 347

Human dermal CD14(+) cells are a transient population of monocyte-derived macrophages

McGovern, N., Schlitzer, A., Gunawan, M., Jardine, L., Shin, A., Poyner, E., Green, K., Dickinson, R., Wang, X.-N., Low, D., et al. (2014) · Immunity

Immunotherapy and Immune ResponsesImmune cells in cancer

Cited by 281

Markers of T Cell Senescence in Humans

Xu, W., & Larbi, A. (2017) · International Journal of Molecular Sciences

Telomeres, Telomerase, and SenescenceT-cell and B-cell Immunology

Cited by 261

Cytomegalovirus Infection: A Driving Force in Human T Cell Immunosenescence

KOCH, S., LARBI, A., ÖZCELIK, D., SOLANA, R., GOUTTEFANGEAS, C., ATTIG, S., WIKBY, A., STRINDHALL, J., FRANCESCHI, C., & PAWELEC, G. (2007) · Annals of the New York Academy of Sciences

Cytomegalovirus and herpesvirus researchHerpesvirus Infections and Treatments

Cited by 242

A subset of Kupffer cells regulates metabolism through the expression of CD36

Blériot, C., Barreby, E., Dunsmore, G., Ballaire, R., Chakarov, S., Ficht, X., De Simone, G., Andreata, F., Fumagalli, V., Guo, W., et al. (2021) · Immunity

Immune cells in cancerLiver physiology and pathology

Cited by 236

The pro-inflammatory phenotype of the human non-classical monocyte subset is attributed to senescence

Ong, S.-M., Hadadi, E., Dang, T.-M., Yeap, W.-H., Tan, C. T.-Y., Ng, T.-P., Larbi, A., & Wong, S.-C. (2018) · Cell Death & Disease

Telomeres, Telomerase, and SenescenceImmune cells in cancer

Cited by 233

Biomarkers of human immunosenescence: impact of cytomegalovirus infection

Derhovanessian, E., Larbi, A., & Pawelec, G. (2009) · Current Opinion in Immunology

Cytomegalovirus and herpesvirus researchTelomeres, Telomerase, and Senescence

Cited by 220

Immunity, ageing and cancer

Derhovanessian, E., Solana, R., Larbi, A., & Pawelec, G. (2008) · Immunity & Ageing

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 169

Cellular signaling in the aging immune system

Fulop, T., Le Page, A., Fortin, C., Witkowski, J. M., Dupuis, G., & Larbi, A. (2014) · Current Opinion in Immunology

Immune Response and InflammationT-cell and B-cell Immunology

Cited by 158

On the immunological theory of aging

Fulop, T., Witkowski, J. M., Pawelec, G., Alan, C., & Larbi, A. (2014) · Interdisciplinary topics in gerontology and geriatrics

Genetics, Aging, and Longevity in Model OrganismsImmune Response and Inflammation

Cited by 157

CXCR4 identifies transitional bone marrow premonocytes that replenish the mature monocyte pool for peripheral responses

Chong, S. Z., Evrard, M., Devi, S., Chen, J., Lim, J. Y., See, P., Zhang, Y., Adrover, J. M., Lee, B., Tan, L., et al. (2016) · Journal of Experimental Medicine

Chemokine receptors and signalingImmune cells in cancer

Cited by 142

Differential role of lipid rafts in the functions of CD4+ and CD8+ human T lymphocytes with aging

Larbi, A., Dupuis, G., Khalil, A., Douziech, N., Fortin, C., & Fülöp, T. (2006) · Cellular Signalling

T-cell and B-cell ImmunologyLipid Membrane Structure and Behavior

Cited by 126

Impact of age on T cell signaling: A general defect or specific alterations?

Larbi, A., Pawelec, G., Wong, S. C., Goldeck, D., Tai, J. J.-Y., & Fulop, T. (2011) · Ageing Research Reviews

T-cell and B-cell ImmunologyImmune Response and Inflammation

Cited by 108

Enhancement of cutaneous immunity during aging by blocking p38 mitogen-activated protein (MAP) kinase-induced inflammation

Vukmanovic-Stejic, M., Chambers, E. S., Suárez-Fariñas, M., Sandhu, D., Fuentes-Duculan, J., Patel, N., Agius, E., Lacy, K. E., Turner, C. T., Larbi, A., et al. (2018) · Journal of Allergy and Clinical Immunology

Herpesvirus Infections and TreatmentsT-cell and B-cell Immunology

Cited by 103

Oxidative stress modulation and T cell activation

Larbi, A., Kempf, J., & Pawelec, G. (2007) · Experimental Gerontology

Redox biology and oxidative stressExercise and Physiological Responses

Cited by 102