Goldman, Steven A.

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Iliff, J. J., Wang, M., Liao, Y., Plogg, B. A., Peng, W., Gundersen, G. A., Benveniste, H., Vates, G. E., Deane, R., Goldman, S. A., et al. (2012) · Science Translational Medicine

Cerebrospinal fluid and hydrocephalusIon Transport and Channel Regulation

Cited by 5,824

Reactive astrocyte nomenclature, definitions, and future directions

Escartin, C., Galea, E., Lakatos, A., O’Callaghan, J. P., Petzold, G. C., Serrano-Pozo, A., Steinhäuser, C., Volterra, A., Carmignoto, G., Agarwal, A., et al. (2021) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 2,513

Uniquely Hominid Features of Adult Human Astrocytes

Oberheim, N. A., Takano, T., Han, X., He, W., Lin, J. H. C., Wang, F., Xu, Q., Wyatt, J. D., Pilcher, W., Ojemann, J. G., et al. (2009) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,488

New roles for astrocytes: redefining the functional architecture of the brain.

Nedergaard, M., Ransom, B., & Goldman, S. A. (2003) · Trends in Neurosciences

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 1,334

Glymphatic failure as a final common pathway to dementia

Nedergaard, M., & Goldman, S. A. (2020) · Science

Cerebrospinal fluid and hydrocephalusSleep and Wakefulness Research

Cited by 1,145

Astrocytic complexity distinguishes the human brain

Oberheim, N. A., Wang, X., Goldman, S., & Nedergaard, M. (2006) · Trends in Neurosciences

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 739

Coordinated Interaction of Neurogenesis and Angiogenesis in the Adult Songbird Brain

Louissaint, A., Rao, S., Leventhal, C., & Goldman, S. A. (2002) · Neuron

Neurogenesis and neuroplasticity mechanismsAngiogenesis and VEGF in Cancer

Cited by 735

Heterogeneity of astrocytic form and function.

Oberheim, N. A., Goldman, S. A., & Nedergaard, M. (2012) · Methods in Molecular Biology

Neuroscience and Neuropharmacology ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 638

Forebrain Engraftment by Human Glial Progenitor Cells Enhances Synaptic Plasticity and Learning in Adult Mice

Han, X., Chen, M., Wang, F., Windrem, M., Wang, S., Shanz, S., Xu, Q., Oberheim, N. A., Bekar, L., Betstadt, S., et al. (2013) · Cell Stem Cell

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 635

Human iPSC-Derived Oligodendrocyte Progenitor Cells Can Myelinate and Rescue a Mouse Model of Congenital Hypomyelination

Wang, S., Bates, J., Li, X., Schanz, S., Chandler-Militello, D., Levine, C., Maherali, N., Studer, L., Hochedlinger, K., Windrem, M., et al. (2013) · Cell Stem Cell

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 586

Adenoviral brain-derived neurotrophic factor induces both neostriatal and olfactory neuronal recruitment from endogenous progenitor cells in the adult forebrain

Benraiss, A., Chmielnicki, E., Lerner, K., Roh, D., & Goldman, S. A. (2001) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNerve injury and regeneration

Cited by 540

Fetal and adult human oligodendrocyte progenitor cell isolates myelinate the congenitally dysmyelinated brain

Windrem, M. S., Nunes, M. C., Rashbaum, W. K., Schwartz, T. H., Goodman, R. A., McKhann, G., Roy, N. S., & Goldman, S. A. (2004) · Nature Medicine

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 451

Purinergic receptor P2RY12-dependent microglial closure of the injured blood–brain barrier

Lou, N., Takano, T., Pei, Y., Xavier, A. L., Goldman, S. A., & Nedergaard, M. (2016) · Proceedings of the National Academy of Sciences

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 364

SOX9 Is an Astrocyte-Specific Nuclear Marker in the Adult Brain Outside the Neurogenic Regions

Sun, W., Cornwell, A., Li, J., Peng, S., Osorio, M. J., Aalling, N., Wang, S., Benraiss, A., Lou, N., Goldman, S. A., et al. (2017) · The Journal of Neuroscience

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 357

A distinct population of microglia supports adult neurogenesis in the subventricular zone

Ribeiro Xavier, A. L., Kress, B. T., Goldman, S. A., Lacerda de Menezes, J. R., & Nedergaard, M. (2015) · Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 225

Human glia can both induce and rescue aspects of disease phenotype in Huntington disease

Benraiss, A., Wang, S., Herrlinger, S., Li, X., Chandler-Militello, D., Mauceri, J., Burm, H. B., Toner, M., Osipovitch, M., Jim Xu, Q., et al. (2016) · Nature Communications

Genetic Neurodegenerative DiseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 199

Potentiating glymphatic drainage minimizes post-traumatic cerebral oedema

Hussain, R., Tithof, J., Wang, W., Cheetham-West, A., Song, W., Peng, W., Sigurdsson, B., Kim, D., Sun, Q., Peng, S., et al. (2023) · Nature

Traumatic Brain Injury and Neurovascular DisturbancesCerebrospinal fluid and hydrocephalus

Cited by 169

Dual regulatory switch through interactions of Tcf7l2/Tcf4 with stage-specific partners propels oligodendroglial maturation

Zhao, C., Deng, Y., Liu, L., Yu, K., Zhang, L., Wang, H., He, X., Wang, J., Lu, C., Wu, L. N., et al. (2016) · Nature Communications

Neurogenesis and neuroplasticity mechanismsWnt/β-catenin signaling in development and cancer

Cited by 154

Human ESC-derived chimeric mouse models of Huntington's disease reveal cell-intrinsic defects in glial progenitor cell differentiation

Osipovitch, M., Asenjo Martinez, A., Mariani, J. N., Cornwell, A., Dhaliwal, S., Zou, L., Chandler-Militello, D., Wang, S., Li, X., Benraiss, S.-J., et al. (2019) · Cell Stem Cell

Genetic Neurodegenerative DiseasesNeurogenesis and neuroplasticity mechanisms

Cited by 120

5-HT 2B receptors are expressed on astrocytes from brain and in culture and are a chronic target for all five conventional ‘serotonin-specific reuptake inhibitors’

Zhang, S., Li, B., Lovatt, D., Xu, J., Song, D., Goldman, S. A., Nedergaard, M., Hertz, L., & Peng, L. (2010) · Neuron Glia Biology

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

Cited by 69

Remyelination in the central nervous system

Franklin, R. J. M., Bodini, B., & Goldman, S. A. (2024) · Cold Spring Harbor Perspectives in Biology

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 40

Glymphatic clearance is enhanced during sleep

Kroesbergen, E., Riesselmann, L. V., Gomolka, R. S., Plá, V., Esmail, T., Stenmo, V. H., Kovács, E. R., Nielsen, E. S., Goldman, S. A., Nedergaard, M., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Cerebrospinal fluid and hydrocephalusSleep and Wakefulness Research

Cited by 32

Glial progenitor cell-based repair of the dysmyelinated brain: Progression to the clinic

Goldman, S. A., Mariani, J. N., & Madsen, P. M. (2021) · Seminars in Cell & Developmental Biology

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 22

A curious concept of CNS clearance

Plá, V., Kroesbergen, E., Deng, S., Giannetto, M. J., Hablitz, L. M., Newbold, E., Ladrón-de-Guevara, A., Esmail, T., Gomolka, R. S., Mori, Y., et al. (2025) · Nature Neuroscience

Cerebrospinal fluid and hydrocephalusSleep and Wakefulness Research

Cited by 15