Engleman, Edgar G.

Immune Checkpoint Inhibitors for the Treatment of Cancer: Clinical Impact and Mechanisms of Response and Resistance

Bagchi, S., Yuan, R., & Engleman, E. G. (2021) · Annual Review of Pathology: Mechanisms of Disease

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 2,189

Vaccination of patients with B–cell lymphoma using autologous antigen–pulsed dendritic cells

Hsu, F. J., Benike, C., Fagnoni, F., Liles, T. M., Czerwinski, D., Taidi, B., Engleman, E. G., & Levy, R. (1996) · Nature Medicine

Immunotherapy and Immune ResponsesLymphoma Diagnosis and Treatment

Cited by 1,804

Normalization of obesity-associated insulin resistance through immunotherapy

Winer, S., Chan, Y., Paltser, G., Truong, D., Tsui, H., Bahrami, J., Dorfman, R., Wang, Y., Zielenski, J., Mastronardi, F., et al. (2009) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesT-cell and B-cell Immunology

Cited by 1,370

B cells promote insulin resistance through modulation of T cells and production of pathogenic IgG antibodies

Winer, D. A., Winer, S., Shen, L., Wadia, P. P., Yantha, J., Paltser, G., Tsui, H., Wu, P., Davidson, M. G., Alonso, M. N., et al. (2011) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesT-cell and B-cell Immunology

Cited by 1,050

Systemic Immunity Is Required for Effective Cancer Immunotherapy

Spitzer, M. H., Carmi, Y., Reticker-Flynn, N. E., Kwek, S. S., Madhireddy, D., Martins, M. M., Gherardini, P. F., Prestwood, T. R., Chabon, J., Bendall, S. C., et al. (2017) · Cell

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 963

pH-independent HIV entry into CD4-positive T cells via virus envelope fusion to the plasma membrane

Stein, B. S., Gowda, S. D., Lifson, J. D., Penhallow, R. C., Bensch, K. G., & Engleman, E. G. (1987) · Cell

HIV Research and TreatmentCellular transport and secretion

Cited by 627

Dehydroepiandrosterone enhances IL2 production and cytotoxic effector function of human T cells.

Suzuki, T., Suzuki, N., Daynes, R. A., & Engleman, E. G. (1991) · Clinical Immunology and Immunopathology

T-cell and B-cell ImmunologyAdrenal Hormones and Disorders

Cited by 277

Insulin Receptor-Mediated Stimulation Boosts T Cell Immunity during Inflammation and Infection

Tsai, S., Clemente-Casares, X., Zhou, A. C., Lei, H., Ahn, J. J., Chan, Y. T., Choi, O., Luck, H., Woo, M., Dunn, S. E., et al. (2018) · Cell Metabolism

T-cell and B-cell ImmunologyMetabolism, Diabetes, and Cancer

Cited by 272

Matrix viscoelasticity promotes liver cancer progression in the pre-cirrhotic liver

Fan, W., Adebowale, K., Váncza, L., Li, Y., Rabbi, M. F., Kunimoto, K., Chen, D., Mozes, G., Chiu, D. K.-C., Li, Y., et al. (2024) · Nature

Cellular Mechanics and InteractionsLiver physiology and pathology

Cited by 263

Mechanical stiffness controls dendritic cell metabolism and function

Chakraborty, M., Chu, K., Shrestha, A., Revelo, X. S., Zhang, X., Gold, M. J., Khan, S., Lee, M., Huang, C., Akbari, M., et al. (2021) · Cell Reports

Cellular Mechanics and InteractionsImmunotherapy and Immune Responses

Cited by 258

Dehydroepiandrosterone in systemic lupus erythematosus

Van Vollenhoven, R. F., Engleman, E. G., & Mcguire, J. L. (1995) · Arthritis & Rheumatism

Systemic Lupus Erythematosus ResearchAdrenal Hormones and Disorders

Cited by 192

Type I Interferon Responses Drive Intrahepatic T Cells to Promote Metabolic Syndrome

Ghazarian, M., Revelo, X. S., Nøhr, M. K., Luck, H., Zeng, K., Lei, H., Tsai, S., Schroer, S. A., Park, Y. J., Chng, M. H. Y., et al. (2017) · Science Immunology

interferon and immune responsesLiver Disease Diagnosis and Treatment

Cited by 190

Intracellular processing of the gp160 HIV-1 envelope precursor. Endoproteolytic cleavage occurs in a cis or medial compartment of the Golgi complex

Stein, B. S., & Engleman, E. G. (1990) · Journal of Biological Chemistry

Cellular transport and secretionHIV Research and Treatment

Cited by 189

Induction of potent antitumor immunity by in situ targeting of intratumoral DCs

Furumoto, K., Soares, L., Engleman, E. G., & Merad, M. (2004) · Journal of Clinical Investigation

Immunotherapy and Immune ResponsesT-cell and B-cell Immunology

Cited by 180

B‐1a lymphocytes attenuate insulin resistance

Shen, L., Chng, M. H. Y., Alonso, M. N., Yuan, R., Winer, D. A., & Engleman, E. G. (2015) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesT-cell and B-cell Immunology

Cited by 109

Identification of cell types in multiplexed in situ images by combining protein expression and spatial information using CELESTA

Zhang, W., Li, I., Reticker-Flynn, N. E., Good, Z., Chang, S., Samusik, N., Saumyaa, S., Li, Y., Zhou, X., Liang, R., et al. (2022) · Nature Methods

Single-cell and spatial transcriptomicsCell Image Analysis Techniques

Cited by 108

Conditional knockout of hypoxia-inducible factor 1-alpha in tumor-infiltrating neutrophils protects against pancreatic ductal adenocarcinoma

Sieow, J. L., Penny, H. L., Gun, S. Y., Tan, L. Q., Duan, K., Yeong, J. P. S., Pang, A., Lim, D., Toh, H. C., Lim, T. K. H., et al. (2023) · International Journal of Molecular Sciences

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 27

A Novel Type of Blood Biomarker: Distinct Changes of Cytokine-Induced STAT Phosphorylation in Blood T Cells Between Colorectal Cancer Patients and Healthy Individuals

Yun, J. W., Lee, S., Kim, H. M., Chun, S., Engleman, E. G., Kim, H. C., & Kang, E.-S. (2019) · Cancers

Cytokine Signaling Pathways and InteractionsT-cell and B-cell Immunology

Cited by 18