Schreiber, Stuart L.
Broad Institute · Harvard University
58 papers on CoChatORCID 0000-0003-1922-7558
Most cited papers
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Identification of cancer-cytotoxic modulators of PDE3A by predictive chemogenomics
de Waal, L., Lewis, T. A., Rees, M. G., Tsherniak, A., Wu, X., Choi, P. S., Gechijian, L., Hartigan, C., Faloon, P. W., Hickey, M. J., et al. (2016) · Nature Chemical Biology
Phosphodiesterase function and regulationComputational Drug Discovery Methods
Cited by 96
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Chemical Genetic Modifier Screens
Koeller, K. M., Haggarty, S. J., Perkins, B. D., Leykin, I., Wong, J. C., Kao, M.-C. J., & Schreiber, S. L. (2003) · Chemistry & Biology
Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics
Cited by 89
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DNA-encoded library-enabled discovery of proximity-inducing small molecules
Mason, J. W., Chow, Y. T., Hudson, L., Tutter, A., Michaud, G., Westphal, M. V., Shu, W., Ma, X., Tan, Z. Y., Coley, C. W., et al. (2024) · Nature Chemical Biology
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 83
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Assigning functionality to cysteines by base editing of cancer dependency genes
Li, H., Ma, T., Remsberg, J. R., Won, S. J., DeMeester, K. E., Njomen, E., Ogasawara, D., Zhao, K. T., Huang, T. P., Lu, B., et al. (2023) · Nature Chemical Biology
Click Chemistry and ApplicationsProtein Degradation and Inhibitors
Cited by 62
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Chemical Genomic Profiling of Biological Networks Using Graph Theory and Combinations of Small Molecule Perturbations
Haggarty, S. J., Clemons, P. A., & Schreiber, S. L. (2003) · Journal of the American Chemical Society
Bioinformatics and Genomic NetworksGene Regulatory Network Analysis
Cited by 61
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Modular, stereocontrolled C β –H/C α –C activation of alkyl carboxylic acids
Shang, M., Feu, K. S., Vantourout, J. C., Barton, L. M., Osswald, H. L., Kato, N., Gagaring, K., McNamara, C. W., Chen, G., Hu, L., et al. (2019) · Proceedings of the National Academy of Sciences
Catalytic C–H Functionalization MethodsCyclopropane Reaction Mechanisms
Cited by 53
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Potentiation of progesterone receptor-mediated transcription by the immunosuppressant FK506.
Tai, P.-K. K., Albers, M. W., McDonnell, D. P., Chang, H., Schreiber, S. L., & Faber, L. E. (1994) · Biochemistry
Signaling Pathways in DiseaseEstrogen and related hormone effects
Cited by 52
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Chemical tools to expand the ligandable proteome: Diversity-oriented synthesis-based photoreactive stereoprobes
Ogasawara, D., Konrad, D. B., Tan, Z. Y., Carey, K. L., Luo, J., Won, S. J., Li, H., Carter, T. R., DeMeester, K. E., Njomen, E., et al. (2024) · Cell Chemical Biology
Click Chemistry and ApplicationsChemical Synthesis and Analysis
Cited by 31
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High-Throughput Screen in Cryptococcus neoformans Identifies a Novel Molecular Scaffold That Inhibits Cell Wall Integrity Pathway Signaling
Hartland, K., Pu, J., Palmer, M., Dandapani, S., Moquist, P. N., Munoz, B., DiDone, L., Schreiber, S. L., & Krysan, D. J. (2016) · ACS Infectious Diseases
Fungal Infections and StudiesAntifungal resistance and susceptibility
Cited by 24
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Discovery of molecular glues that bind FKBP12 and novel targets using DNA-barcoded libraries
Zandi, T. A., Romanowski, M. J., Viscomi, J. S., Tan, Z. Y., Tong, B., Bonazzi, S., Zécri, F. J., Schreiber, S. L., & Michaud, G. A. (2024) · bioRxiv (Cold Spring Harbor Laboratory)
Protein Degradation and InhibitorsChemical Synthesis and Analysis
Cited by 10
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