Langin, Dominique

Transcriptional Control of Brown Fat Determination by PRDM16

Seale, P., Kajimura, S., Yang, W., Chin, S., Rohas, L. M., Uldry, M., Tavernier, G., Langin, D., & Spiegelman, B. M. (2007) · Cell Metabolism

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 1,174

Reduction of Macrophage Infiltration and Chemoattractant Gene Expression Changes in White Adipose Tissue of Morbidly Obese Subjects After Surgery-Induced Weight Loss

Cancello, R., Henegar, C., Viguerie, N., Taleb, S., Poitou, C., Rouault, C., Coupaye, M., Pelloux, V., Hugol, D., Bouillot, J.-L., et al. (2005) · Diabetes

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 1,164

Weight loss regulates inflammation‐related genes in white adipose tissue of obese subjects

ClÉment, K., Viguerie, N., Poitou, C., Carette, C., Pelloux, V., Curat, C. A., Sicard, A., Rome, S., Benis, A., Zucker, J., et al. (2004) · The FASEB Journal

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 640

Acquirement of brown fat cell features by human white adipocytes

Tiraby, C., Tavernier, G., Lefort, C., Larrouy, D., Bouillaud, F., Ricquier, D., & Langin, D. (2003) · Journal of Biological Chemistry

Adipose Tissue and MetabolismPeroxisome Proliferator-Activated Receptors

Cited by 474

Adipose tissue transcriptomic signature highlights the pathological relevance of extracellular matrix in human obesity

Henegar, C., Tordjman, J., Achard, V., Lacasa, D., Cremer, I., Guerre-Millo, M., Poitou, C., Basdevant, A., Stich, V., Viguerie, N., et al. (2008) · Genome Biology

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 471

Effect of endurance training on skeletal muscle myokine expression in obese men: Identification of apelin as a novel myokine

Besse-Patin, A., Montastier, E., Vinel, C., Castan-Laurell, I., Louche, K., Dray, C., Daviaud, D., Mir, L., Marques, M.-A., Thalamas, C., et al. (2014) · International Journal of Obesity

Exercise and Physiological ResponsesApelin-related biomedical research

Cited by 227

Irf5 deficiency in macrophages promotes beneficial adipose tissue expansion and insulin sensitivity during obesity

Dalmas, E., Toubal, A., Alzaid, F., Blazek, K., Eames, H. L., Lebozec, K., Pini, M., Hainault, I., Montastier, E., Denis, R. G. P., et al. (2015) · Nature Medicine

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 205

An integrated single cell and spatial transcriptomic map of human white adipose tissue

Massier, L., Jalkanen, J., Elmastas, M., Zhong, J., Wang, T., Nono Nankam, P. A., Frendo-Cumbo, S., Bäckdahl, J., Subramanian, N., Sekine, T., et al. (2023) · Nature Communications

Single-cell and spatial transcriptomicsAdipose Tissue and Metabolism

Cited by 195

In Vivo Regulation of Human Skeletal Muscle Gene Expression by Thyroid Hormone

Clément, K., Viguerie, N., Diehn, M., Alizadeh, A., Barbe, P., Thalamas, C., Storey, J. D., Brown, P. O., Barsh, G. S., & Langin, D. (2002) · Genome Research

Thyroid Disorders and TreatmentsEstrogen and related hormone effects

Cited by 169

Immune Cell Toll-like Receptor 4 Mediates the Development of Obesity- and Endotoxemia-Associated Adipose Tissue Fibrosis

Vila, I. K., Badin, P.-M., Marques, M.-A., Monbrun, L., Lefort, C., Mir, L., Louche, K., Bourlier, V., Roussel, B., Gui, P., et al. (2014) · Cell Reports

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 165

Pretreatment Fasting Plasma Glucose and Insulin Modify Dietary Weight Loss Success: Results from 3 Randomized Clinical Trials

Hjorth, M. F., Ritz, C., Blaak, E. E., Saris, W. H., Langin, D., Poulsen, S. K., Larsen, T. M., Sørensen, T. I., Zohar, Y., & Astrup, A. (2017) · The American Journal of Clinical Nutrition

Nutrition, Genetics, and DiseaseDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 165

Cathepsin S, a novel biomarker of adiposity: relevance to atherogenesis

Taleb, S., Lacasa, D., Bastard, J., Poitou, C., Cancello, R., Pelloux, V., Viguerie, N., Benis, A., Zucker, J., Bouillot, J., et al. (2005) · The FASEB Journal

Adipokines, Inflammation, and Metabolic DiseasesCardiovascular Disease and Adiposity

Cited by 158

Importance of TNFα and neutral lipases in human adipose tissue lipolysis

Langin, D., & Arner, P. (2006) · Trends in Endocrinology & Metabolism

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 140

Growth and differentiation factor 15 is secreted by skeletal muscle during exercise and promotes lipolysis in humans

Laurens, C., Parmar, A., Murphy, E., Carper, D., Lair, B., Maes, P., Vion, J., Boulet, N., Fontaine, C., Marquès, M., et al. (2020) · JCI Insight

GDF15 and Related BiomarkersAdipose Tissue and Metabolism

Cited by 135

Altered Skeletal Muscle Lipase Expression and Activity Contribute to Insulin Resistance in Humans

Badin, P.-M., Louche, K., Mairal, A., Liebisch, G., Schmitz, G., Rustan, A. C., Smith, S. R., Langin, D., & Moro, C. (2011) · Diabetes

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 132

Triiodothyronine‐mediated upregulation of UCP2 and UCP3 mRNA expression in human skeletal muscle without coordinated induction of mitochondrial respiratory chain genes

Barbe, P., Larrouy, D., Boulanger, C., Chevillotte, E., Viguerie, N., Thalamas, C., Oliva Trastoy, M., Roques, M., Vidal, H., & Langin, D. (2001) · The FASEB Journal

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 118

Regulation of inflammation-related genes in human adipose tissue

Clement, K., & Langin, D. (2007) · Journal of Internal Medicine

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 98

Fat Oxidation before and after a High Fat Load in the Obese Insulin-Resistant State

Blaak, E. E., Hul, G., Verdich, C., Stich, V., Martinez, A., Petersen, M., Feskens, E. F. M., Patel, K., Oppert, J. M., Barbe, P., et al. (2006) · The Journal of Clinical Endocrinology & Metabolism

Diabetes, Cardiovascular Risks, and LipoproteinsAdipokines, Inflammation, and Metabolic Diseases

Cited by 97

The Transcriptional Coactivator Peroxisome Proliferator–Activated Receptor (PPAR)γ Coactivator-1α and the Nuclear Receptor PPARα Control the Expression of Glycerol Kinase and Metabolism Genes Independently of PPARγ Activation in Human White Adipocytes

Mazzucotelli, A., Viguerie, N., Tiraby, C., Annicotte, J.-S., Mairal, A., Klimcakova, E., Lepin, E., Delmar, P., Dejean, S., Tavernier, G., et al. (2007) · Diabetes

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 90

Dynamics of skeletal muscle lipid pools

Badin, P.-M., Langin, D., & Moro, C. (2013) · Trends in Endocrinology & Metabolism

Lipid metabolism and biosynthesisAdipose Tissue and Metabolism

Cited by 80

Transcriptomics applied to obesity and caloric restriction

Viguerie, N., Poitou, C., Cancello, R., Stich, V., Clément, K., & Langin, D. (2005) · Biochimie

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 74

Fatty acid-induced mitochondrial uncoupling in adipocytes is not a promising target for treatment of insulin resistance unless adipocyte oxidative capacity is increased

Frayn, K. N., Langin, D., & Karpe, F. (2008) · Diabetologia

Adipose Tissue and MetabolismLipid metabolism and biosynthesis

Cited by 54

Primary defects in lipolysis and insulin action in skeletal muscle cells from type 2 diabetic individuals

Kase, E. T., Feng, Y. Z., Badin, P.-M., Bakke, S. S., Laurens, C., Coue, M., Langin, D., Gaster, M., Thoresen, G. H., Rustan, A. C., et al. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Lipid metabolism and biosynthesisLipid metabolism and disorders

Cited by 36