Anderson, Daniel G.

Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing

Yin, H., Song, C.-Q., Suresh, S., Wu, Q., Walsh, S., Rhym, L. H., Mintzer, E., Bolukbasi, M. F., Zhu, L. J., Kauffman, K., et al. (2017) · Nature Biotechnology

CRISPR and Genetic EngineeringRNA Interference and Gene Delivery

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Lipopeptide nanoparticles for potent and selective siRNA delivery in rodents and nonhuman primates

Dong, Y., Love, K. T., Dorkin, J. R., Sirirungruang, S., Zhang, Y., Chen, D., Bogorad, R. L., Yin, H., Chen, Y., Vegas, A. J., et al. (2014) · Proceedings of the National Academy of Sciences

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 488

RNA Circularization Diminishes Immunogenicity and Can Extend Translation Duration In Vivo

Wesselhoeft, R. A., Kowalski, P. S., Parker-Hale, F. C., Huang, Y., Bisaria, N., & Anderson, D. G. (2019) · Molecular Cell

Circular RNAs in diseasesRNA Interference and Gene Delivery

Cited by 482

Sustained antigen availability during germinal center initiation enhances antibody responses to vaccination

Tam, H. H., Melo, M. B., Kang, M., Pelet, J. M., Ruda, V. M., Foley, M. H., Hu, J. K., Kumari, S., Crampton, J., Baldeon, A. D., et al. (2016) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentImmunotherapy and Immune Responses

Cited by 425

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and Toxoplasma gondii challenges with a single dose

Chahal, J. S., Khan, O. F., Cooper, C. L., McPartlan, J. S., Tsosie, J. K., Tilley, L. D., Sidik, S. M., Lourido, S., Langer, R., Bavari, S., et al. (2016) · Proceedings of the National Academy of Sciences

Immunotherapy and Immune ResponsesDendrimers and Hyperbranched Polymers

Cited by 414

Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

Bochenek, M. A., Veiseh, O., Vegas, A. J., McGarrigle, J. J., Qi, M., Marchese, E., Omami, M., Doloff, J. C., Mendoza-Elias, J., Nourmohammadzadeh, M., et al. (2018) · Nature Biomedical Engineering

Pancreatic function and diabetesTissue Engineering and Regenerative Medicine

Cited by 367

Adenovirus-Mediated Somatic Genome Editing of Pten by CRISPR/Cas9 in Mouse Liver in Spite of Cas9-Specific Immune Responses

Wang, D., Mou, H., Li, S., Li, Y., Hough, S., Tran, K., Li, J., Yin, H., Anderson, D. G., Sontheimer, E. J., et al. (2015) · Human Gene Therapy

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 345

Synergistic lipid compositions for albumin receptor mediated delivery of mRNA to the liver

Miao, L., Lin, J., Huang, Y., Li, L., Delcassian, D., Ge, Y., Shi, Y., & Anderson, D. G. (2020) · Nature Communications

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 343

Barcoded nanoparticles for high throughput in vivo discovery of targeted therapeutics

Dahlman, J. E., Kauffman, K. J., Xing, Y., Shaw, T. E., Mir, F. F., Dlott, C. C., Langer, R., Anderson, D. G., & Wang, E. T. (2017) · Proceedings of the National Academy of Sciences

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 335

FGF Regulates TGF-β Signaling and Endothelial-to-Mesenchymal Transition via Control of let-7 miRNA Expression

Chen, P.-Y., Qin, L., Barnes, C., Charisse, K., Yi, T., Zhang, X., Ali, R., Medina, P. P., Yu, J., Slack, F. J., et al. (2012) · Cell Reports

TGF-β signaling in diseasesMicroRNA in disease regulation

Cited by 304

Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates

Doloff, J. C., Veiseh, O., Vegas, A. J., Tam, H. H., Farah, S., Ma, M., Li, J., Bader, A., Chiu, A., Sadraei, A., et al. (2017) · Nature Materials

Orthopaedic implants and arthroplastyTissue Engineering and Regenerative Medicine

Cited by 283

Partial DNA-guided Cas9 enables genome editing with reduced off-target activity

Yin, H., Song, C.-Q., Suresh, S., Kwan, S.-Y., Wu, Q., Walsh, S., Ding, J., Bogorad, R. L., Zhu, L. J., Wolfe, S. A., et al. (2018) · Nature Chemical Biology

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 240

Accelerating ionizable lipid discovery for mRNA delivery using machine learning and combinatorial chemistry

Li, B., Raji, I. O., Gordon, A. G. R., Sun, L., Raimondo, T. M., Oladimeji, F. A., Jiang, A. Y., Varley, A., Langer, R. S., & Anderson, D. G. (2024) · Nature Materials

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 236

Reduction of measurement noise in a continuous glucose monitor by coating the sensor with a zwitterionic polymer

Xie, X., Doloff, J. C., Yesilyurt, V., Sadraei, A., McGarrigle, J. J., Omami, M., Veiseh, O., Farah, S., Isa, D., Ghani, S., et al. (2018) · Nature Biomedical Engineering

Electrochemical sensors and biosensorsDiabetes Management and Research

Cited by 235

Optimization of a degradable polymer–lipid nanoparticle for potent systemic delivery of mRNA to the lung endothelium and immune cells

Kaczmarek, J. C., Kauffman, K. J., Fenton, O. S., Sadtler, K., Patel, A. K., Heartlein, M. W., DeRosa, F., & Anderson, D. G. (2018) · Nano Letters

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 218

mRNA Delivery for Therapeutic Anti-HER2 Antibody Expression In Vivo

Rybakova, Y., Kowalski, P. S., Huang, Y., Gonzalez, J. T., Heartlein, M. W., DeRosa, F., Delcassian, D., & Anderson, D. G. (2019) · Molecular Therapy

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 218

Adenine base editing in an adult mouse model of tyrosinaemia

Song, C.-Q., Jiang, T., Richter, M., Rhym, L. H., Koblan, L. W., Zafra, M. P., Schatoff, E. M., Doman, J. L., Cao, Y., Dow, L. E., et al. (2019) · Nature Biomedical Engineering

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 200

Multiparametric approach for the evaluation of lipid nanoparticles for siRNA delivery

Alabi, C. A., Love, K. T., Sahay, G., Yin, H., Luly, K. M., Langer, R., & Anderson, D. G. (2013) · Proceedings of the National Academy of Sciences

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 188

Long-term implant fibrosis prevention in rodents and non-human primates using crystallized drug formulations

Farah, S., Doloff, J. C., Müller, P., Sadraei, A., Han, H. J., Olafson, K., Vyas, K., Tam, H. H., Hollister-Lock, J., Kowalski, P. S., et al. (2019) · Nature Materials

Advanced Drug Delivery SystemsTissue Engineering and Regenerative Medicine

Cited by 181

Macrophages retain hematopoietic stem cells in the spleen via VCAM-1

Dutta, P., Hoyer, F. F., Grigoryeva, L. S., Sager, H. B., Leuschner, F., Courties, G., Borodovsky, A., Novobrantseva, T., Ruda, V. M., Fitzgerald, K., et al. (2015) · Journal of Experimental Medicine

Hematopoietic Stem Cell TransplantationAtherosclerosis and Cardiovascular Diseases

Cited by 180

Ly6Clo monocytes drive immunosuppression and confer resistance to anti-VEGFR2 cancer therapy

Jung, K., Heishi, T., Khan, O. F., Kowalski, P. S., Incio, J., Rahbari, N. N., Chung, E., Clark, J. W., Willett, C. G., Luster, A. D., et al. (2017) · Journal of Clinical Investigation

Immune cells in cancerAngiogenesis and VEGF in Cancer

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Therapeutic efficacy in a hemophilia B model using a biosynthetic mRNA liver depot system

DeRosa, F., Guild, B., Karve, S., Smith, L., Love, K., Dorkin, J. R., Kauffman, K. J., Zhang, J., Yahalom, B., Anderson, D. G., et al. (2016) · Gene Therapy

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 159

Stretchable Polymeric Multielectrode Array for Conformal Neural Interfacing

Guo, L., Ma, M., Zhang, N., Langer, R., & Anderson, D. G. (2014) · Advanced Materials

Neuroscience and Neural EngineeringConducting polymers and applications

Cited by 128

Enhanced function of immuno-isolated islets in diabetes therapy by co-encapsulation with an anti-inflammatory drug

Dang, T. T., Thai, A. V., Cohen, J., Slosberg, J. E., Siniakowicz, K., Doloff, J. C., Ma, M., Hollister-Lock, J., Tang, K. M., Gu, Z., et al. (2013) · Biomaterials

Pancreatic function and diabetesTissue Engineering and Regenerative Medicine

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