Artandi, Steven E.

Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice

Artandi, S. E., Chang, S., Lee, S.-L., Alson, S., Gottlieb, G. J., Chin, L., & DePinho, R. A. (2000) · Nature

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,085

The Tabula Sapiens: A multiple-organ, single-cell transcriptomic atlas of humans

The Tabula Sapiens Consortium*, Jones, R. C., Karkanias, J., Krasnow, M. A., Pisco, A. O., Quake, S. R., Salzman, J., Yosef, N., Bulthaup, B., Brown, P., et al. (2022) · Science

Single-cell and spatial transcriptomicsGenomics and Chromatin Dynamics

Cited by 1,056

p53 Deficiency Rescues the Adverse Effects of Telomere Loss and Cooperates with Telomere Dysfunction to Accelerate Carcinogenesis

Chin, L., Artandi, S. E., Shen, Q., Tam, A., Lee, S.-L., Gottlieb, G. J., Greider, C. W., & DePinho, R. A. (1999) · Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 979

Telomeres and telomerase in cancer

Artandi, S. E., & DePinho, R. A. (2010) · Carcinogenesis

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 823

Telomerase modulates Wnt signalling by association with target gene chromatin

Park, J.-I., Venteicher, A. S., Hong, J. Y., Choi, J., Jun, S., Shkreli, M., Chang, W., Meng, Z., Cheung, P., Ji, H., et al. (2009) · Nature

Wnt/β-catenin signaling in development and cancerTelomeres, Telomerase, and Senescence

Cited by 707

A Human Telomerase Holoenzyme Protein Required for Cajal Body Localization and Telomere Synthesis

Venteicher, A. S., Abreu, E. B., Meng, Z., McCann, K. E., Terns, R. M., Veenstra, T. D., Terns, M. P., & Artandi, S. E. (2009) · Science

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 522

Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice

Sacco, A., Mourkioti, F., Tran, R., Choi, J., Llewellyn, M., Kraft, P., Shkreli, M., Delp, S., Pomerantz, J. H., Artandi, S. E., et al. (2010) · Cell

Muscle Physiology and DisordersNeurogenetic and Muscular Disorders Research

Cited by 512

Conditional telomerase induction causes proliferation of hair follicle stem cells

Sarin, K. Y., Cheung, P., Gilison, D., Lee, E., Tennen, R. I., Wang, E., Artandi, M. K., Oro, A. E., & Artandi, S. E. (2005) · Nature

Hair Growth and DisordersTelomeres, Telomerase, and Senescence

Cited by 425

TERT Promotes Epithelial Proliferation through Transcriptional Control of a Myc- and Wnt-Related Developmental Program

Choi, J., Southworth, L. K., Sarin, K. Y., Venteicher, A. S., Ma, W., Chang, W., Cheung, P., Jun, S., Artandi, M. K., Shah, N., et al. (2008) · PLoS Genetics

Hair Growth and DisordersTelomeres, Telomerase, and Senescence

Cited by 336

Identification of ATPases Pontin and Reptin as Telomerase Components Essential for Holoenzyme Assembly

Venteicher, A. S., Meng, Z., Mason, P. J., Veenstra, T. D., & Artandi, S. E. (2008) · Cell

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 329

A critical role for telomeres in suppressing and facilitating carcinogenesis

Artandi, S. E., & DePinho, R. A. (2000) · Current Opinion in Genetics & Development

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 318

Constitutive telomerase expression promotes mammary carcinomas in aging mice

Artandi, S. E., Alson, S., Tietze, M. K., Sharpless, N. E., Ye, S., Greenberg, R. A., Castrillon, D. H., Horner, J. W., Weiler, S. R., Carrasco, R. D., et al. (2002) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 317

Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation

Wong, K.-K., Chang, S., Weiler, S. R., Ganesan, S., Chaudhuri, J., Zhu, C., Artandi, S. E., Rudolph, K. L., Gottlieb, G. J., Chin, L., et al. (2000) · Nature Genetics

Telomeres, Telomerase, and SenescenceEffects of Radiation Exposure

Cited by 309

Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita

Zhong, F., Savage, S. A., Shkreli, M., Giri, N., Jessop, L., Myers, T., Chen, R., Alter, B. P., & Artandi, S. E. (2011) · Genes & Development

Telomeres, Telomerase, and SenescenceNuclear Structure and Function

Cited by 262

Telomere dysfunction provokes regional amplification and deletion in cancer genomes

O'Hagan, R. C., Chang, S., Maser, R. S., Mohan, R., Artandi, S. E., Chin, L., & DePinho, R. A. (2002) · Cancer Cell

Telomeres, Telomerase, and SenescenceGenomic variations and chromosomal abnormalities

Cited by 246

Distributed hepatocytes expressing telomerase repopulate the liver in homeostasis and injury

Lin, S., Nascimento, E. M., Gajera, C. R., Chen, L., Neuhöfer, P., Garbuzov, A., Wang, S., & Artandi, S. E. (2018) · Nature

Liver physiology and pathologyMesenchymal stem cell research

Cited by 241

A Platform for Rapid Exploration of Aging and Diseases in a Naturally Short-Lived Vertebrate

Harel, I., Benayoun, B. A., Machado, B., Singh, P. P., Hu, C.-K., Pech, M. F., Valenzano, D. R., Zhang, E., Sharp, S. C., Artandi, S. E., et al. (2015) · Cell

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 232

Mice without telomerase: what can they teach us about human cancer?

Artandi, S. E., & DePinho, R. A. (2000) · Nature Medicine

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 126

Cell types of origin of the cell-free transcriptome

Vorperian, S. K., Moufarrej, M. N., Tabula Sapiens Consortium, Overall Project Direction and Coordination, Jones, R. C., Karkanias, J., Krasnow, M., Pisco, A. O., Quake, S. R., Salzman, J., et al. (2022) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 116

Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo

Rajaraman, S., Choi, J., Cheung, P., Beaudry, V., Moore, H., & Artandi, S. E. (2007) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 44

Telomere shortening and cell fates in mouse models of neoplasia

Artandi, S. E. (2002) · Trends in Molecular Medicine

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 40