Joosten, Leo A. B.

Interplay between Candida albicans and the mammalian innate host defense

Cheng, S.-C., Joosten, L. A. B., Kullberg, B.-J., & Netea, M. G. (2012) · Infection and Immunity

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 256

Reactive oxygen species–independent activation of the IL-1β inflammasome in cells from patients with chronic granulomatous disease

van de Veerdonk, F. L., Smeekens, S. P., Joosten, L. A. B., Kullberg, B. J., Dinarello, C. A., van der Meer, J. W. M., & Netea, M. G. (2010) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 248

Trained Immunity-Promoting Nanobiologic Therapy Suppresses Tumor Growth and Potentiates Checkpoint Inhibition

Priem, B., van Leent, M. M. T., Teunissen, A. J. P., Sofias, A. M., Mourits, V. P., Willemsen, L., Klein, E. D., Oosterwijk, R. S., Meerwaldt, A. E., Munitz, J., et al. (2020) · Cell

Immunotherapy and Immune ResponsesCancer Immunotherapy and Biomarkers

Cited by 222

Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans

Smeekens, S. P., Ng, A., Kumar, V., Johnson, M. D., Plantinga, T. S., van Diemen, C., Arts, P., Verwiel, E. T. P., Gresnigt, M. S., Fransen, K., et al. (2013) · Nature Communications

Antifungal resistance and susceptibilityinterferon and immune responses

Cited by 213

Evolutionary and Functional Analysis of Celiac Risk Loci Reveals SH2B3 as a Protective Factor against Bacterial Infection

Zhernakova, A., Elbers, C. C., Ferwerda, B., Romanos, J., Trynka, G., Dubois, P. C., de Kovel, C. G. F., Franke, L., Oosting, M., Barisani, D., et al. (2010) · The American Journal of Human Genetics

Celiac Disease Research and ManagementGenetic Associations and Epidemiology

Cited by 195

The dectin-1/inflammasome pathway is responsible for the induction of protective T-helper 17 responses that discriminate between yeasts and hyphae of Candida albicans

Cheng, S.-C., van de Veerdonk, F. L., Lenardon, M., Stoffels, M., Plantinga, T., Smeekens, S., Rizzetto, L., Mukaremera, L., Preechasuth, K., Cavalieri, D., et al. (2011) · Journal of Leukocyte Biology

Antifungal resistance and susceptibilityInflammasome and immune disorders

Cited by 191

Gut Microbial Associations to Plasma Metabolites Linked to Cardiovascular Phenotypes and Risk: A Cross-Sectional Study

Kurilshikov, A., van den Munckhof, I. C. L., Chen, L., Bonder, M. J., Schraa, K., Rutten, J. H. W., Riksen, N. P., de Graaf, J., Oosting, M., Sanna, S., et al. (2019) · Circulation Research

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 178

Host genetic regulation of human gut microbial structural variation

Zhernakova, D. V., Wang, D., Liu, L., Andreu-Sánchez, S., Zhang, Y., Ruiz-Moreno, A. J., Peng, H., Plomp, N., Del Castillo-Izquierdo, Á., Gacesa, R., et al. (2024) · Nature

Gut microbiota and healthGenetic Associations and Epidemiology

Cited by 174

A Polysaccharide Virulence Factor from Aspergillus fumigatus Elicits Anti-inflammatory Effects through Induction of Interleukin-1 Receptor Antagonist

Gresnigt, M. S., Bozza, S., Becker, K. L., Joosten, L. A. B., Abdollahi-Roodsaz, S., van der Berg, W. B., Dinarello, C. A., Netea, M. G., Fontaine, T., De Luca, A., et al. (2014) · PLoS Pathogens

Antifungal resistance and susceptibilityFungal and yeast genetics research

Cited by 142

Suppression of monosodium urate crystal-induced cytokine production by butyrate is mediated by the inhibition of class I histone deacetylases

Cleophas, M. C. P., Crişan, T. O., Lemmers, H., Toenhake-Dijkstra, H., Fossati, G., Jansen, T. L., Dinarello, C. A., Netea, M. G., & Joosten, L. A. B. (2016) · Annals of the Rheumatic Diseases

Gout, Hyperuricemia, Uric AcidInflammasome and immune disorders

Cited by 139

Role of dectin-2 for host defense against systemic infection with Candida glabrata

Ifrim, D. C., Bain, J. M., Reid, D. M., Oosting, M., Verschueren, I., Gow, N. A. R., van Krieken, J. H., Brown, G. D., Kullberg, B.-J., Joosten, L. A. B., et al. (2014) · Infection and Immunity

Antifungal resistance and susceptibilityImmune Response and Inflammation

Cited by 117

Antibody neutralization of microbiota-derived circulating peptidoglycan dampens inflammation and ameliorates autoimmunity

Huang, Z., Wang, J., Xu, X., Wang, H., Qiao, Y., Chu, W. C., Xu, S., Chai, L., Cottier, F., Pavelka, N., et al. (2019) · Nature Microbiology

Immune Response and InflammationGut microbiota and health

Cited by 107

Safety and COVID-19 Symptoms in Individuals Recently Vaccinated with BCG: a Retrospective Cohort Study

Moorlag, S. J. C. F. M., van Deuren, R. C., van Werkhoven, C. H., Jaeger, M., Debisarun, P., Taks, E., Mourits, V. P., Koeken, V. A. C. M., de Bree, L. C. J., ten Doesschate, T., et al. (2020) · Cell Reports Medicine

Immune responses and vaccinationsSARS-CoV-2 and COVID-19 Research

Cited by 96

Gut microbiome-mediated metabolism effects on immunity in rural and urban African populations

Stražar, M., Temba, G. S., Vlamakis, H., Kullaya, V. I., Lyamuya, F., Mmbaga, B. T., Joosten, L. A. B., van der Ven, A. J. A. M., Netea, M. G., de Mast, Q., et al. (2021) · Nature Communications

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 91

Pattern recognition pathways leading to a Th2 cytokine bias in allergic bronchopulmonary aspergillosis patients

Becker, K. L., Gresnigt, M. S., Smeekens, S. P., Jacobs, C. W., Magis‐Escurra, C., Jaeger, M., Wang, X., Lubbers, R., Oosting, M., Joosten, L. A. B., et al. (2015) · Clinical & Experimental Allergy

Asthma and respiratory diseasesAntifungal resistance and susceptibility

Cited by 83

Aspergillus Cell Wall Chitin Induces Anti- and Proinflammatory Cytokines in Human PBMCs via the Fc-γ Receptor/Syk/PI3K Pathway

Becker, K. L., Aimanianda, V., Wang, X., Gresnigt, M. S., Ammerdorffer, A., Jacobs, C. W., Gazendam, R. P., Joosten, L. A. B., Netea, M. G., Latgé, J. P., et al. (2016) · mBio

Studies on Chitinases and ChitosanasesImmune Response and Inflammation

Cited by 73

Factors modulating the inflammatory response in acute gouty arthritis

Cleophas, M. C., Crişan, T. O., & Joosten, L. A. B. (2017) · Current Opinion in Rheumatology

Gout, Hyperuricemia, Uric AcidInflammasome and immune disorders

Cited by 62

Differential effects of IL-17 pathway in disseminated candidiasis and zymosan-induced multiple organ failure

van de Veerdonk, F. L., Kullberg, B. J., Verschueren, I. C., Hendriks, T., van der Meer, J. W. M., Joosten, L. A. B., & Netea, M. G. (2010) · Shock

Antifungal resistance and susceptibilitySepsis Diagnosis and Treatment

Cited by 49

Neisseria meningitidis lipid A mutant LPSs function as LPS antagonists in humans by inhibiting TLR 4-dependent cytokine production

Sprong, T., Ley, P. V. D., Abdollahi-Roodsaz, S., Joosten, L., Meer, J. V. D., Netea, M., & Deuren, M. V. (2011) · Innate Immunity

Immune Response and InflammationBacterial Infections and Vaccines

Cited by 20

MAP3K8 (TPL2/COT) Affects Obesity-Induced Adipose Tissue Inflammation without Systemic Effects in Humans and in Mice

Ballak, D. B., van Essen, P., van Diepen, J. A., Jansen, H., Hijmans, A., Matsuguchi, T., Sparrer, H., Tack, C. J., Netea, M. G., Joosten, L. A. B., et al. (2014) · PLoS ONE

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 20

Low Interleukin-17A Production in Response to Fungal Pathogens in Patients with Chronic Granulomatous Disease

Smeekens, S. P., Henriet, S. S. V., Gresnigt, M. S., Joosten, L. A. B., Hermans, P. W. M., Netea, M. G., Warris, A., & van de Veerdonk, F. L. (2012) · Journal of Interferon & Cytokine Research

Neutrophil, Myeloperoxidase and Oxidative MechanismsImmunodeficiency and Autoimmune Disorders

Cited by 20

Toll-like receptor 2 induced cytotoxic T-lymphocyte-associated protein 4 regulates Aspergillus-induced regulatory T-cells with pro-inflammatory characteristics

Raijmakers, R. P. H., Sprenkeler, E. G. G., Aleva, F. E., Jacobs, C. W. M., Kanneganti, T.-D., Joosten, L. A. B., van de Veerdonk, F. L., & Gresnigt, M. S. (2017) · Scientific Reports

T-cell and B-cell ImmunologyAsthma and respiratory diseases

Cited by 16

Distinct Genetic Determinants of Plasma Inflammatory Proteins in Tanzanian and Dutch Populations

Amour, C., Boahen, C. K., Temba, G. S., Vadaq, N., Kullaya, V., Mmbaga, B. T., Joosten, L. A. B., Kavishe, R. A., Netea, M. G., de Mast, Q., et al. (2026) · Genomics, Proteomics & Bioinformatics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 0