Zrenner, Eberhart

Subretinal electronic chips allow blind patients to read letters and combine them to words

Zrenner, E., Bartz-Schmidt, K. U., Benav, H., Besch, D., Bruckmann, A., Gabel, V.-P., Gekeler, F., Greppmaier, U., Harscher, A., Kibbel, S., et al. (2011) · Proceedings of the Royal Society B: Biological Sciences

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 819

Artificial vision with wirelessly powered subretinal electronic implant alpha-IMS

Stingl, K., Bartz-Schmidt, K. U., Besch, D., Braun, A., Bruckmann, A., Gekeler, F., Greppmaier, U., Hipp, S., Hörtdörfer, G., Kernstock, C., et al. (2013) · Proceedings of the Royal Society B: Biological Sciences

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 473

Subretinal visual implant alpha IMS - clinical trial interim report

Stingl, K., Bartz-Schmidt, K. U., Besch, D., Chee, C. K., Cottriall, C. L., Gekeler, F., Groppe, M., Jackson, T. L., MacLaren, R. E., Koitschev, A., et al. (2015) · Vision Research

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 387

Interim results of a multicenter trial with the new electronic subretinal implant Alpha AMS in 15 Patients blind from inherited retinal degenerations.

Stingl, K., Schippert, R., Bartz-Schmidt, K. U., Besch, D., Cottriall, C. L., Edwards, T. L., Gekeler, F., Greppmaier, U., Kiel, K., Koitschev, A., et al. (2017) · Frontiers in Neuroscience

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 198

Assessment of the electronic retinal implant alpha AMS in restoring vision to blind patients with end-stage retinitis pigmentosa

Edwards, T. L., Cottriall, C. L., Xue, K., Simunovic, M. P., Ramsden, J. D., Zrenner, E., & MacLaren, R. E. (2018) · Ophthalmology

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 193

Safety and Vision Outcomes of Subretinal Gene Therapy Targeting Cone Photoreceptors in Achromatopsia: A Nonrandomized Controlled Trial

Fischer, M. D., Michalakis, S., Wilhelm, B., Zobor, D., Muehlfriedel, R., Kohl, S., Weisschuh, N., Ochakovski, G. A., Klein, R., Schoen, C., et al. (2020) · JAMA Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 177

Spatial resolution and perception of patterns mediated by a subretinal 16-electrode array in patients blinded by hereditary retinal dystrophies

Wilke, R., Gabel, V.-P., Sachs, H., Bartz Schmidt, K.-U., Gekeler, F., Besch, D., Szurman, P., Stett, A., Wilhelm, B., Peters, T., et al. (2011) · Investigative Opthalmology & Visual Science

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 155

Superior retinal gene transfer and biodistribution profile of subretinal versus intravitreal delivery of AAV8 in nonhuman primates

Seitz, I. P., Michalakis, S., Wilhelm, B., Reichel, F. F., Ochakovski, G. A., Zrenner, E., Ueffing, M., Biel, M., Wissinger, B., Bartz-Schmidt, K. U., et al. (2017) · Investigative Opthalmology & Visual Science

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 108

Efficacy and Safety of Retinal Gene Therapy Using Adeno-Associated Virus Vector for Patients With Choroideremia: A Randomized Clinical Trial

Fischer, M. D., Ochakovski, G. A., Beier, B., Seitz, I. P., Vaheb, Y., Kortuem, C., Reichel, F. F. L., Kuehlewein, L., Kahle, N. A., Peters, T., et al. (2019) · JAMA Ophthalmology

Retinal Development and DisordersVirus-based gene therapy research

Cited by 92

Bioengineering strategies for restoring vision

Cehajic-Kapetanovic, J., Singh, M. S., Zrenner, E., & MacLaren, R. E. (2022) · Nature Biomedical Engineering

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 79

Safety and Proof-of-Concept Study of Oral QLT091001 in Retinitis Pigmentosa Due to Inherited Deficiencies of Retinal Pigment Epithelial 65 Protein (RPE65) or Lecithin:Retinol Acyltransferase (LRAT)

Scholl, H. P. N., Moore, A. T., Koenekoop, R. K., Wen, Y., Fishman, G. A., van den Born, L. I., Bittner, A., Bowles, K., Fletcher, E. C., Collison, F. T., et al. (2015) · PLOS ONE

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 71

Changes in Retinal Sensitivity after Gene Therapy in Choroideremia

Fischer, M. D., Ochakovski, G. A., Beier, B., Seitz, I. P., Vaheb, Y., Kortuem, C., Reichel, F. F. L., Kuehlewein, L., Kahle, N. A., Peters, T., et al. (2020) · Retina

Retinal Development and DisordersVirus-based gene therapy research

Cited by 66

Phosphene thresholds elicited by transcorneal electrical stimulation in healthy subjects and patients with retinal diseases

Naycheva, L., Schatz, A., Röck, T., Willmann, G., Messias, A., Bartz-Schmidt, K. U., Zrenner, E., & Gekeler, F. (2012) · Investigative Opthalmology & Visual Science

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 55

Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degeneration

Sahaboglu, A., Barth, M., Secer, E., Amo, E. M. D., Urtti, A., Arsenijevic, Y., Zrenner, E., & Paquet-Durand, F. (2016) · Scientific Reports

Retinal Development and DisordersPARP inhibition in cancer therapy

Cited by 53

HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice

Samardzija, M., Corna, A., Gomez-Sintes, R., Jarboui, M. A., Armento, A., Roger, J. E., Petridou, E., Haq, W., Paquet-Durand, F., Zrenner, E., et al. (2021) · Cell Death & Differentiation

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 48

Oculomotor behavior of blind patients seeing with a subretinal visual implant

Hafed, Z. M., Stingl, K., Bartz-Schmidt, K.-U., Gekeler, F., & Zrenner, E. (2016) · Vision Research

Neuroscience and Neural EngineeringGaze Tracking and Assistive Technology

Cited by 43

The Subretinal Implant ALPHA: Implantation and Functional Results

Zrenner, E., Bartz-Schmidt, K. U., Besch, D., Gekeler, F., Koitschev, A., Sachs, H. G., & Stingl, K. (2017) · Artificial Vision

Neuroscience and Neural EngineeringRetinal Development and Disorders

Cited by 27