McGavern, Dorian B.

Microglia development and function

Nayak, D., Roth, T. L., & McGavern, D. B. (2014) · Annual Review of Immunology

Neuroinflammation and Neurodegeneration MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,154

Inflammation and neuroprotection in traumatic brain injury.

Corps, K. N., Roth, T. L., & McGavern, D. B. (2015) · JAMA Neurology

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 853

Neuroimmunology of Traumatic Brain Injury: Time for a Paradigm Shift

Jassam, Y. N., Izzy, S., Whalen, M., McGavern, D. B., & El Khoury, J. (2017) · Neuron

Traumatic Brain Injury and Neurovascular DisturbancesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 799

A lymphocyte–microglia–astrocyte axis in chronic active multiple sclerosis

Absinta, M., Maric, D., Gharagozloo, M., Garton, T., Smith, M. D., Jin, J., Fitzgerald, K. C., Song, A., Liu, P., Lin, J.-P., et al. (2021) · Nature

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 768

Transcranial amelioration of inflammation and cell death after brain injury.

Roth, T. L., Nayak, D., Atanasijevic, T., Koretsky, A. P., Latour, L. L., & McGavern, D. B. (2014) · Nature

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 574

Single-cell RNA-seq reveals TOX as a key regulator of CD8+ T cell persistence in chronic infection

Yao, C., Sun, H.-W., Lacey, N. E., Ji, Y., Moseman, E. A., Shih, H.-Y., Heuston, E. F., Kirby, M., Anderson, S., Cheng, J., et al. (2019) · Nature Immunology

T-cell and B-cell ImmunologyCancer Immunotherapy and Biomarkers

Cited by 549

Differentiation of human and murine induced pluripotent stem cells to microglia-like cells

Pandya, H., Shen, M. J., Ichikawa, D. M., Sedlock, A. B., Choi, Y., Johnson, K. R., Kim, G., Brown, M. A., Elkahloun, A. G., Maric, D., et al. (2017) · Nature Neuroscience

Pluripotent Stem Cells ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 405

The anatomy and immunology of vasculature in the central nervous system

Mastorakos, P., & McGavern, D. (2019) · Science Immunology

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 333

Advances in Meningeal Immunity

Rua, R., & McGavern, D. B. (2018) · Trends in Molecular Medicine

Neuroinflammation and Neurodegeneration MechanismsMigraine and Headache Studies

Cited by 326

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

Kim, J. V., Kang, S. S., Dustin, M. L., & McGavern, D. B. (2009) · Nature

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 326

Illuminating viral infections in the nervous system

McGavern, D. B., & Kang, S. S. (2011) · Nature Reviews Immunology

interferon and immune responsesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 281

Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system

Konradt, C., Ueno, N., Christian, D. A., Delong, J. H., Pritchard, G. H., Herz, J., Bzik, D. J., Koshy, A. A., McGavern, D. B., Lodoen, M. B., et al. (2016) · Nature Microbiology

Toxoplasma gondii Research StudiesBarrier Structure and Function Studies

Cited by 193

Immune Surveillance of the CNS following Infection and Injury

Russo, M. V., & McGavern, D. B. (2015) · Trends in Immunology

Neuroinflammation and Neurodegeneration MechanismsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 191

T cell engagement of cross-presenting microglia protects the brain from a nasal virus infection

Moseman, E. A., Blanchard, A. C., Nayak, D., & McGavern, D. B. (2020) · Science Immunology

Neuroinflammation and Neurodegeneration MechanismsImmunotherapy and Immune Responses

Cited by 157

Distinct myeloid cell subsets promote meningeal remodeling and vascular repair after mild traumatic brain injury

Russo, M. V., Latour, L. L., & McGavern, D. B. (2018) · Nature Immunology

Traumatic Brain Injury and Neurovascular DisturbancesTraumatic Brain Injury Research

Cited by 149

CD8+ T Cells Induce Fatal Brainstem Pathology during Cerebral Malaria via Luminal Antigen-Specific Engagement of Brain Vasculature

Swanson, P. A., Hart, G. T., Russo, M. V., Nayak, D., Yazew, T., Peña, M., Khan, S. M., Janse, C. J., Pierce, S. K., & McGavern, D. B. (2016) · PLOS Pathogens

Malaria Research and ControlBarrier Structure and Function Studies

Cited by 125

Infection drives meningeal engraftment by inflammatory monocytes that impairs CNS immunity

Rua, R., Lee, J. Y., Silva, A. B., Swafford, I. S., Maric, D., Johnson, K. R., & McGavern, D. B. (2019) · Nature Immunology

Neuroinflammation and Neurodegeneration MechanismsImmune responses and vaccinations

Cited by 123

A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection

Marsolais, D., Hahm, B., Walsh, K. B., Edelmann, K. H., McGavern, D., Hatta, Y., Kawaoka, Y., Rosen, H., & Oldstone, M. B. A. (2009) · Proceedings of the National Academy of Sciences

Influenza Virus Research StudiesSphingolipid Metabolism and Signaling

Cited by 122

Temporally distinct myeloid cell responses mediate damage and repair after cerebrovascular injury

Mastorakos, P., Mihelson, N., Luby, M., Burks, S. R., Johnson, K., Hsia, A. W., Witko, J., Frank, J. A., Latour, L., & McGavern, D. B. (2021) · Nature Neuroscience

Neuroinflammation and Neurodegeneration MechanismsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 113

In vivo dynamics of innate immune sentinels in the CNS

Nayak, D., Zinselmeyer, B. H., Corps, K. N., & McGavern, D. B. (2012) · IntraVital

Neuroinflammation and Neurodegeneration MechanismsInflammasome and immune disorders

Cited by 109

Systemic inflammation in early neonatal mice induces transient and lasting neurodegenerative effects

Cardoso, F. L., Herz, J., Fernandes, A., Rocha, J., Sepodes, B., Brito, M. A., McGavern, D. B., & Brites, D. (2015) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsNeonatal and fetal brain pathology

Cited by 103

Mucosal-associated invariant T cells restrict reactive oxidative damage and preserve meningeal barrier integrity and cognitive function

Zhang, Y., Bailey, J. T., Xu, E., Singh, K., Lavaert, M., Link, V. M., D’Souza, S., Hafiz, A., Cao, J., Cao, G., et al. (2022) · Nature Immunology

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 91

Immunological defense of CNS barriers against infections

Ampie, L., & McGavern, D. B. (2022) · Immunity

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 63

MRI confirms loss of blood–brain barrier integrity in a mouse model of disseminated candidiasis

Navarathna, D. H. M. L. P., Munasinghe, J., Lizak, M. J., Nayak, D., McGavern, D. B., & Roberts, D. D. (2013) · NMR in Biomedicine

Antifungal resistance and susceptibilityBarrier Structure and Function Studies

Cited by 34