Advances in Meningeal Immunity

Neutrophil Emigration in the Skin, Lungs, and Peritoneum: Different Requirements for CD11/CD18 Revealed by CD18-deficient Mice

Mizgerd, J. P., Kubo, H., Kutkoski, G. J., Bhagwan, S. D., Scharffetter-Kochanek, K., Beaudet, A. L., & Doerschuk, C. M. (1997) · The Journal of Experimental Medicine · doi:10.1084/jem.186.8.1357 · Cited by 7,332 · see citing works

A Paravascular Pathway Facilitates CSF Flow Through the Brain Parenchyma and the Clearance of Interstitial Solutes, Including Amyloid β

Iliff, J. J., Wang, M., Liao, Y., Plogg, B. A., Peng, W., Gundersen, G. A., Benveniste, H., Vates, G. E., Deane, R., Goldman, S. A., et al. (2012) · Science Translational Medicine · doi:10.1126/scitranslmed.3003748 · Cited by 5,824 · see citing works

Structural and functional features of central nervous system lymphatic vessels

Louveau, A., Smirnov, I., Keyes, T. J., Eccles, J. D., Rouhani, S. J., Peske, J. D., Derecki, N. C., Castle, D., Mandell, J. W., Lee, K. S., et al. (2015) · Nature · doi:10.1038/nature14432 · Cited by 4,413 · see citing works

In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus

Azevedo, R. S. S., de Sousa, J. R., Araujo, M. T. F., Martins Filho, A. J., de Alcantara, B. N., Araujo, F. M. C., Queiroz, M. G. L., Cruz, A. C. R., Vasconcelos, B. H. B., Chiang, J. O., et al. (2018) · Scientific Reports · doi:10.1038/s41598-017-17765-5 · Cited by 3,478 · see citing works

A dural lymphatic vascular system that drains brain interstitial fluid and macromolecules

Aspelund, A., Antila, S., Proulx, S. T., Karlsen, T. V., Karaman, S., Detmar, M., Wiig, H., & Alitalo, K. (2015) · Journal of Experimental Medicine · doi:10.1084/jem.20142290 · Cited by 2,198 · see citing works

Meningeal B-cell follicles in secondary progressive multiple sclerosis associate with early onset of disease and severe cortical pathology

Magliozzi, R., Howell, O. W., Vora, A., Serafini, B., Nicholas, R. S., Puopolo, M., Reynolds, R., & Aloisi, F. (2006) · Brain · doi:10.1093/brain/awm038 · Cited by 1,444 · see citing works

Intravascular Danger Signals Guide Neutrophils to Sites of Sterile Inflammation

McDonald, B., Pittman, K., Menezes, G. B., Hirota, S. A., Slaba, I., Waterhouse, C. C. M., Beck, P. L., Muruve, D. A., & Kubes, P. (2010) · Science · doi:10.1126/science.1195491 · Cited by 1,210 · see citing works

Origin, fate and dynamics of macrophages at central nervous system interfaces

Goldmann, T., Wieghofer, P., Jordão, M. J. C., Prutek, F., Hagemeyer, N., Frenzel, K., Amann, L., Staszewski, O., Kierdorf, K., Krueger, M., et al. (2016) · Nature Immunology · doi:10.1038/ni.3423 · Cited by 1,209 · see citing works

RORγt drives production of the cytokine GM-CSF in helper T cells, which is essential for the effector phase of autoimmune neuroinflammation

Codarri, L., Gyülvészi, G., Tosevski, V., Hesske, L., Fontana, A., Magnenat, L., Suter, T., & Becher, B. (2011) · Nature Immunology · doi:10.1038/ni.2027 · Cited by 1,191 · see citing works

Microglia development and function

Nayak, D., Roth, T. L., & McGavern, D. B. (2014) · Annual Review of Immunology · doi:10.1146/annurev-immunol-032713-120240 · Cited by 1,154 · see citing works

Commensal microbiota affects ischemic stroke outcome by regulating intestinal γδ T cells

Benakis, C., Brea, D., Caballero, S., Faraco, G., Moore, J., Murphy, M., Sita, G., Racchumi, G., Ling, L., Pamer, E. G., et al. (2016) · Nature Medicine · doi:10.1038/nm.4068 · Cited by 1,114 · see citing works

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

Gelderblom, M., Leypoldt, F., Steinbach, K., Behrens, D., Choe, C.-U., Siler, D. A., Arumugam, T. V., Orthey, E., Gerloff, C., Tolosa, E., et al. (2009) · Stroke · doi:10.1161/strokeaha.108.534503 · Cited by 1,066 · see citing works

Three or more routes for leukocyte migration into the central nervous system

Ransohoff, R. M., Kivisäkk, P., & Kidd, G. (2003) · Nature Reviews Immunology · doi:10.1038/nri1130 · Cited by 1,052 · see citing works

High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

Mrdjen, D., Pavlovic, A., Hartmann, F. J., Schreiner, B., Utz, S. G., Leung, B. P., Lelios, I., Heppner, F. L., Kipnis, J., Merkler, D., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.01.011 · Cited by 1,010 · see citing works

Dendritic cells permit immune invasion of the CNS in an animal model of multiple sclerosis

Greter, M., Heppner, F. L., Lemos, M. P., Odermatt, B. M., Goebels, N., Laufer, T., Noelle, R. J., & Becher, B. (2005) · Nature Medicine · doi:10.1038/nm1197 · Cited by 862 · see citing works

Inflammation and neuroprotection in traumatic brain injury.

Corps, K. N., Roth, T. L., & McGavern, D. B. (2015) · JAMA Neurology · doi:10.1001/jamaneurol.2014.3558 · Cited by 853 · see citing works

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

Shichita, T., Sugiyama, Y., Ooboshi, H., Sugimori, H., Nakagawa, R., Takada, I., Iwaki, T., Okada, Y., Iida, M., Cua, D. J., et al. (2009) · Nature Medicine · doi:10.1038/nm.1999 · Cited by 842 · see citing works

Regulation of learning and memory by meningeal immunity: a key role for IL-4

Derecki, N. C., Cardani, A. N., Yang, C. H., Quinnies, K. M., Crihfield, A., Lynch, K. R., & Kipnis, J. (2010) · Journal of Experimental Medicine · doi:10.1084/jem.20091419 · Cited by 800 · see citing works

What is immune privilege (not)?

Galea, I., Bechmann, I., & Perry, V. H. (2007) · Trends in Immunology · doi:10.1016/j.it.2006.11.004 · Cited by 768 · see citing works

Sensitization of meningeal sensory neurons and the origin of headaches

Strassman, A. M., Raymond, S. A., & Burstein, R. (1996) · Nature · doi:10.1038/384560a0 · Cited by 704 · see citing works

Unexpected role of interferon-γ in regulating neuronal connectivity and social behaviour

Filiano, A. J., Xu, Y., Tustison, N. J., Marsh, R. L., Baker, W., Smirnov, I., Overall, C. C., Gadani, S. P., Turner, S. D., Weng, Z., et al. (2016) · Nature · doi:10.1038/nature18626 · Cited by 697 · see citing works

Outflow of cerebrospinal fluid is predominantly through lymphatic vessels and is reduced in aged mice

Ma, Q., Ineichen, B. V., Detmar, M., & Proulx, S. T. (2017) · Nature Communications · doi:10.1038/s41467-017-01484-6 · Cited by 690 · see citing works

Capture, crawl, cross: the T cell code to breach the blood–brain barriers

Engelhardt, B., & Ransohoff, R. M. (2012) · Trends in Immunology · doi:10.1016/j.it.2012.07.004 · Cited by 686 · see citing works

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions.

Bartholomäus, I., Kawakami, N., Odoardi, F., Schläger, C., Miljkovic, D., Ellwart, J. W., Klinkert, W. E. F., Flügel-Koch, C., Issekutz, T. B., Wekerle, H., et al. (2009) · Nature · doi:10.1038/nature08478 · Cited by 685 · see citing works

Recruitment of Beneficial M2 Macrophages to Injured Spinal Cord Is Orchestrated by Remote Brain Choroid Plexus

Shechter, R., Miller, O., Yovel, G., Rosenzweig, N., London, A., Ruckh, J., Kim, K.-W., Klein, E., Kalchenko, V., Bendel, P., et al. (2013) · Immunity · doi:10.1016/j.immuni.2013.02.012 · Cited by 683 · see citing works

Migraine Headache Triggered Specifically by Sunlight: Report of 16 Cases

Tekataş, A., & Mungen, B. (2013) · European Neurology · doi:10.1159/000354165 · Cited by 665 · see citing works

Targeting Neutrophils in Ischemic Stroke: Translational Insights from Experimental Studies

Jickling, G. C., Liu, D., Ander, B. P., Stamova, B., Zhan, X., & Sharp, F. R. (2015) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1038/jcbfm.2015.45 · Cited by 644 · see citing works

Human and nonhuman primate meninges harbor lymphatic vessels that can be visualized noninvasively by MRI.

Absinta, M., Ha, S.-K., Nair, G., Sati, P., Luciano, N. J., Palisoc, M., Louveau, A., Zaghloul, K. A., Pittaluga, S., Kipnis, J., et al. (2017) · eLife · doi:10.7554/elife.29738 · Cited by 643 · see citing works

Transcranial amelioration of inflammation and cell death after brain injury.

Roth, T. L., Nayak, D., Atanasijevic, T., Koretsky, A. P., Latour, L. L., & McGavern, D. B. (2014) · Nature · doi:10.1038/nature12808 · Cited by 574 · cited 9× · see citing works

Human cerebrospinal fluid central memory CD4 + T cells: Evidence for trafficking through choroid plexus and meninges via P-selectin

Kivisäkk, P., Mahad, D., Callahan, M. K., Trebst, C., Tucky, B. H., Wei, T., Wu, L., Bækkevold, E. S., Lassmann, H., Staugaitis, S. M., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1433000100 · Cited by 546 · see citing works

T cell deficiency leads to cognitive dysfunction: Implications for therapeutic vaccination for schizophrenia and other psychiatric conditions

Kipnis, J., Cohen, H., Cardon, M., Ziv, Y., & Schwartz, M. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0402268101 · Cited by 510 · see citing works

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

Gelderblom, M., Weymar, A., Bernreuther, C., Velden, J., Arunachalam, P., Steinbach, K., Orthey, E., Arumugam, T. V., Leypoldt, F., Simova, O., et al. (2012) · Blood · doi:10.1182/blood-2012-02-412726 · Cited by 457 · see citing works

A balanced view of the cerebrospinal fluid composition and functions: Focus on adult humans

Spector, R., Snodgrass, S. R., & Johanson, C. E. (2015) · Experimental Neurology · doi:10.1016/j.expneurol.2015.07.027 · Cited by 445 · see citing works

Neurogenically mediated leakage of plasma protein occurs from blood vessels in dura mater but not brain

Markowitz, S., Saito, K., & Moskowitz, M. (1987) · Journal of Neuroscience · doi:10.1523/jneurosci.07-12-04129.1987 · Cited by 441 · see citing works

High-dimensional, single-cell characterization of the brain's immune compartment

Korin, B., Ben-Shaanan, T. L., Schiller, M., Dubovik, T., Azulay‐Debby, H., Boshnak, N., Koren, T., & Rolls, A. (2017) · Nature Neuroscience · doi:10.1038/nn.4610 · Cited by 423 · see citing works

Mast Cells Enhance T Cell Activation: Importance of Mast Cell Costimulatory Molecules and Secreted TNF

Nakae, S., Suto, H., Iikura, M., Kakurai, M., Sedgwick, J. D., Tsai, M. M., & Galli, S. J. (2006) · The Journal of Immunology · doi:10.4049/jimmunol.176.4.2238 · Cited by 412 · see citing works

Activation of Meningeal Nociceptors by Cortical Spreading Depression: Implications for Migraine with Aura

Zhang, X., Levy, D., Noseda, R., Kainz, V., Jakubowski, M., & Burstein, R. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.0511-10.2010 · Cited by 408 · see citing works

Ontogeny and homeostasis of CNS myeloid cells

Prinz, M., Erny, D., & Hagemeyer, N. (2017) · Nature Immunology · doi:10.1038/ni.3703 · Cited by 391 · see citing works

Animal models of multiple sclerosis: the good, the bad and the bottom line

Ransohoff, R. M. (2012) · Nature Neuroscience · doi:10.1038/nn.3168 · Cited by 379 · see citing works

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid

Schläger, C., Körner, H., Krueger, M., Vidoli, S., Haberl, M., Mielke, D., Brylla, E., Issekutz, T., Cabañas, C., Nelson, P. J., et al. (2016) · Nature · doi:10.1038/nature16939 · Cited by 372 · see citing works

Mast cell degranulation activates a pain pathway underlying migraine headache

Levy, D., Burstein, R., Kainz, V., et al. (2007) · Pain · doi:10.1016/j.pain.2007.03.012 · Cited by 371 · see citing works

Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma

Smith, A. J., Yao, X., Dix, J. A., Jin, B.-J., & Verkman, A. S. (2017) · eLife · doi:10.7554/elife.27679 · Cited by 362 · see citing works

Avenues for entry of peripherally administered protein to the central nervous system in mouse, rat, and squirrel monkey.

Balin, B. J., Broadwell, R. D., Salcman, M., & El‐Kalliny, M. (1986) · Journal of Comparative Neurology · doi:10.1002/cne.902510209 · Cited by 358 · see citing works

Regulation of cerebrospinal fluid (CSF) flow in neurodegenerative, neurovascular and neuroinflammatory disease

Simon, M. J., & Iliff, J. J. (2015) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease · doi:10.1016/j.bbadis.2015.10.014 · Cited by 339 · see citing works

CD4-positive T lymphocytes provide a neuroimmunological link in the control of adult hippocampal neurogenesis

Wolf, S. A., Steiner, B., Akpinarli, A., Kammertoens, T., Nassenstein, C., Braun, A., Blankenstein, T., & Kempermann, G. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0801218 · Cited by 329 · see citing works

Inflammatory cell trafficking across the blood–brain barrier: chemokine regulation and in vitro models

Takeshita, Y., & Ransohoff, R. M. (2012) · Immunological Reviews · doi:10.1111/j.1600-065x.2012.01127.x · Cited by 327 · see citing works

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

Kim, J. V., Kang, S. S., Dustin, M. L., & McGavern, D. B. (2009) · Nature · doi:10.1038/nature07591 · Cited by 326 · see citing works

Blocking CGRP in migraine patients – a review of pros and cons

Deen, M., Correnti, E., Kamm, K., Kelderman, T., Papetti, L., Rubio‐Beltrán, E., Vigneri, S., Edvinsson, L. I., & MaassenVanDenBrink, A. (2017) · The Journal of Headache and Pain · doi:10.1186/s10194-017-0807-1 · Cited by 301 · see citing works

Nerve fibres and their terminals of the dura mater encephali of the rat

Andres, K. H., D�ring, M., Muszynski, K., & Schmidt, R. F. (1987) · Anatomy and Embryology · doi:10.1007/bf00309843 · Cited by 289 · see citing works

Localizing central nervous system immune surveillance: Meningeal antigen‐presenting cells activate T cells during experimental autoimmune encephalomyelitis

Kivisäkk, P., Imitola, J., Rasmussen, S. O., Elyaman, W., Zhu, B., Ransohoff, R. M., & Khoury, S. J. (2008) · Annals of Neurology · doi:10.1002/ana.21379 · Cited by 287 · see citing works

Reperfusion therapy in acute ischemic stroke: dawn of a new era?

Bhaskar, S. M. M., Stanwell, P., Cordato, D. J., Attia, J., & Levi, C. R. (2018) · BMC Neurology · doi:10.1186/s12883-017-1007-y · Cited by 251 · see citing works

Comparative anatomy and histology : a mouse and human atlas

Treuting, P. M., & Dintzis, S. M. (2012) · doi:10.1016/c2009-0-61166-1 · Cited by 241 · see citing works

Depletion of Ly6G/Gr-1 Leukocytes after Spinal Cord Injury in Mice Alters Wound Healing and Worsens Neurological Outcome

Stirling, D. P., Liu, S., Kubes, P., & Yong, V. W. (2009) · Journal of Neuroscience · doi:10.1523/jneurosci.4918-08.2009 · Cited by 234 · see citing works

Integration of Th17- and lymphotoxin-derived signals initiates meningeal-resident stromal cell remodeling to propagate neuroinflammation.

Pikor, N. B., Astarita, J. L., Summers-Deluca, L., Galicia, G., Qu, J., Ward, L. A., Armstrong, S., Dominguez, C. X., Malhotra, D., Heiden, B., et al. (2015) · Immunity · doi:10.1016/j.immuni.2015.11.010 · Cited by 229 · see citing works

The neurovascular unit as a selective barrier to polymorphonuclear granulocyte (PMN) infiltration into the brain after ischemic injury

Enzmann, G., Mysiorek, C., Gorina, R., Cheng, Y.-J., Ghavampour, S., Hannocks, M.-J., Prinz, V., Dirnagl, U., Endres, M., Prinz, M., et al. (2013) · Acta Neuropathologica · doi:10.1007/s00401-012-1076-3 · Cited by 225 · see citing works

Adaptive immunity affects learning behavior in mice

Brynskikh, A., Warren, T., Zhu, J., & Kipnis, J. (2008) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2007.12.008 · Cited by 221 · see citing works

High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease

Mrdjen, D., Pavlovic, A., Hartmann, F. J., Schreiner, B., Utz, S. G., Leung, B. P., Lelios, I., Heppner, F. L., Kipnis, J., Merkler, D., et al. (2018) · Immunity · doi:10.1016/j.immuni.2018.02.014 · Cited by 220 · cited 3× · see citing works

Interactions of innate and adaptive immunity in brain development and function

Filiano, A. J., Gadani, S. P., & Kipnis, J. (2014) · Brain Research · doi:10.1016/j.brainres.2014.07.050 · Cited by 217 · see citing works

MHCII-independent CD4+ T cells protect injured CNS neurons via IL-4.

Walsh, J. T., Hendrix, S., Boato, F., Smirnov, I., Zheng, J., Lukens, J. R., Gadani, S. P., Hechler, D., Gölz, G., Rosenberger, K., et al. (2015) · Journal of Clinical Investigation · doi:10.1172/jci76210 · Cited by 208 · see citing works

Brain perivascular macrophages: characterization and functional roles in health and disease

Faraco, G., Park, L., Anrather, J., & Iadecola, C. (2017) · Journal of Molecular Medicine · doi:10.1007/s00109-017-1573-x · Cited by 206 · see citing works

Sensory innervation of the calvarial bones of the mouse

Kosaras, B., Jakubowski, M., Kainz, V., et al. (2009) · The Journal of Comparative Neurology · doi:10.1002/cne.22049 · Cited by 205 · see citing works

Molecular characterization of perivascular drainage pathways in the murine brain

Hannocks, M.-J., Pizzo, M. E., Huppert, J., Deshpande, T., Abbott, N. J., Thorne, R. G., & Sorokin, L. (2018) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x17749689 · Cited by 201 · see citing works

Time course and distribution of inflammatory and neurodegenerative events suggest structural bases for the pathogenesis of experimental autoimmune encephalomyelitis

Brown, D. A., & Sawchenko, P. E. (2007) · The Journal of Comparative Neurology · doi:10.1002/cne.21307 · Cited by 200 · see citing works

How and why do T cells and their derived cytokines affect the injured and healthy brain?

Filiano, A. J., Gadani, S. P., & Kipnis, J. (2017) · Nature Reviews Neuroscience · doi:10.1038/nrn.2017.39 · Cited by 199 · see citing works

Migraine pain, meningeal inflammation, and mast cells

Levy, D. (2009) · Current Pain and Headache Reports · doi:10.1007/s11916-009-0040-y · Cited by 191 · see citing works

Peptidergic and serotoninergic innervation of the rat dura mater

Keller, J. T., & Marfurt, C. F. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903090408 · Cited by 184 · see citing works

Mannose receptor expression specifically reveals perivascular macrophages in normal, injured, and diseased mouse brain

Galea, I., Palin, K., Newman, T. A., van Rooijen, N., Perry, V. H., & Boche, D. (2004) · Glia · doi:10.1002/glia.20124 · Cited by 183 · see citing works

Neurovascular contributions to migraine: Moving beyond vasodilation

Jacobs, B. A., & Dussor, G. O. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.06.012 · Cited by 182 · see citing works

Brain Endothelial- and Epithelial-Specific Interferon Receptor Chain 1 Drives Virus-Induced Sickness Behavior and Cognitive Impairment

Blank, T., Detje, C. N., Spieß, A., Hagemeyer, N., Brendecke, S. M., Wolfart, J., Staszewski, O., Zöller, T., Papageorgiou, I. E., Schneider, J., et al. (2016) · Immunity · doi:10.1016/j.immuni.2016.04.005 · Cited by 179 · see citing works

The spectrum of neuropathological changes associated with congenital Zika virus infection

Chimelli, L. M. C., Melo, A., Portari, E. A., Wiley, C. A., Camacho, A. H. S., Lopes, V. S., Machado, H. N., de Andrade, C. V., Dock, D. C. D. A., Moreira, M. E. L., et al. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1699-5 · Cited by 168 · see citing works

Behavior of Parasite-Specific Effector CD8+ T Cells in the Brain and Visualization of a Kinesis-Associated System of Reticular Fibers

Wilson, E. H., Harris, T. H., Mrass, P., John, B., Wojno, E. D. T., Wu, G. F., Pepper, M., Wherry, E. J., Dzierzinski, F., Roos, D. S., et al. (2009) · Immunity · doi:10.1016/j.immuni.2008.12.013 · Cited by 167 · see citing works

Pattern of intracranial and extracranial projections of trigeminal ganglion cells

O'Connor, T., & van der Kooy, D. (1986) · Journal of Neuroscience · doi:10.1523/jneurosci.06-08-02200.1986 · Cited by 166 · see citing works

Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE

Christy, A. L., Walker, M. E., Hessner, M. J., & Brown, M. A. (2012) · Journal of Autoimmunity · doi:10.1016/j.jaut.2012.11.003 · Cited by 165 · see citing works

Meningeal Mast Cells Affect Early T Cell Central Nervous System Infiltration and Blood-Brain Barrier Integrity through TNF: A Role for Neutrophil Recruitment?

Sayed, B. A., Christy, A. L., Walker, M. E., & Brown, M. A. (2010) · The Journal of Immunology · doi:10.4049/jimmunol.1000126 · Cited by 163 · see citing works

Cerebrospinal Fluid in Clinical Practice

Jellinger, K. A. (2009) · European Journal of Neurology · doi:10.1111/j.1468-1331.2009.02601.x · Cited by 161 · see citing works

Mast cell–derived TNF can promote Th17 cell–dependent neutrophil recruitment in ovalbumin-challenged OTII mice

Nakae, S., Suto, H., Berry, G. J., & Galli, S. J. (2006) · Blood · doi:10.1182/blood-2006-09-046128 · Cited by 160 · see citing works

THE MEMBRANOUS COVERINGS OF NEURAL TISSUES: AN ELECTORN MICROSCOPY STUDY

WAGGENER, J. D., & BEGGS, J. (1967) · Journal of Neuropathology and Experimental Neurology · doi:10.1097/00005072-196707000-00005 · Cited by 154 · see citing works

Inducible MHC Class II Expression by Mast Cells Supports Effector and Regulatory T Cell Activation

Kambayashi, T., Allenspach, E. J., Chang, J. T., Zou, T., Shoag, J. E., Reiner, S. L., Caton, A. J., & Koretzky, G. A. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0803180 · Cited by 153 · see citing works

Central memory CD4+ T cells dominate the normal cerebrospinal fluid

de Graaf, M. T., Smitt, P. A. E. S., Luitwieler, R. L., et al. (2010) · Cytometry Part B Clinical Cytometry · doi:10.1002/cyto.b.20542 · Cited by 149 · see citing works

Cortical grey matter demyelination can be induced by elevated pro-inflammatory cytokines in the subarachnoid space of MOG-immunized rats

Gardner, C., Magliozzi, R., Durrenberger, P. F., Howell, O. W., Rundle, J., & Reynolds, R. (2013) · Brain · doi:10.1093/brain/awt279 · Cited by 148 · see citing works

Characterization of meningeal type 2 innate lymphocytes and their response to CNS injury

Gadani, S. P., Smirnov, I., Wiltbank, A. T., Overall, C. C., & Kipnis, J. (2016) · The Journal of Experimental Medicine · doi:10.1084/jem.20161982 · Cited by 148 · see citing works

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity

Lodygin, D., Odoardi, F., Schläger, C., Körner, H., Kitz, A., Nosov, M., van den Brandt, J., Reichardt, H. M., Haberl, M., & Flügel, A. (2013) · Nature Medicine · doi:10.1038/nm.3182 · Cited by 144 · see citing works

Brain antigen-reactive CD4+ T cells are sufficient to support learning behavior in mice with limited T cell repertoire

Radjavi, A., Smirnov, I., & Kipnis, J. (2013) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2013.08.013 · Cited by 135 · see citing works

Drug transporters on arachnoid barrier cells contribute to the blood-cerebrospinal fluid barrier

Yasuda, K., Cline, C., Vogel, P., Onciu, M., Fatima, S., Sorrentino, B. P., Thirumaran, R. K., Ekins, S., Urade, Y., Fujimori, K., et al. (2013) · Drug Metabolism and Disposition · doi:10.1124/dmd.112.050344 · Cited by 128 · see citing works

Activation of Meningeal 5‐HT2B Receptors: An Early Step in the Generation of Migraine Headache?

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The collagenic architecture of human dura mater

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