Hen, René

Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation

Sahay, A., Scobie, K. N., Hill, A. S., O'Carroll, C. M., Kheirbek, M. A., Burghardt, N. S., Fenton, A. A., Dranovsky, A., & Hen, R. (2011) · Nature

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,567

Human Hippocampal Neurogenesis Persists throughout Aging

Boldrini, M., Fulmore, C. A., Tartt, A. N., Simeon, L. R., Pavlova, I., Poposka, V., Rosoklija, G. B., Stankov, A., Arango, V., Dwork, A. J., et al. (2018) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,345

Neurogenesis-dependent and -independent effects of fluoxetine in an animal model of anxiety/depression

David, D. J., Samuels, B. A., Rainer, Q., Wang, J.-W., Marsteller, D., Mendez, I., Drew, M., Craig, D. A., Guiard, B. P., Guilloux, J.-P., et al. (2009) · Neuron

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 1,267

Ablation of hippocampal neurogenesis impairs contextual fear conditioning and synaptic plasticity in the dentate gyrus

Saxe, M. D., Battaglia, F., Wang, J.-W., Malleret, G., David, D. J., Monckton, J. E., Garcia, A. D. R., Sofroniew, M. V., Kandel, E. R., Santarelli, L., et al. (2006) · Proceedings of the National Academy of Sciences

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,020

Adult hippocampal neurogenesis and cognitive flexibility — linking memory and mood

Anacker, C., & Hen, R. (2017) · Nature Reviews Neuroscience

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,014

The SV40 72 base repair repeat has a striking effect on gene expression both in SV40 and other chimeric recombinants

Moreau, P., Hen, R., Wasylyk, B., Everett, R., Gaub, M. P., & Chambon, P. (1981) · Nucleic Acids Research

Polyomavirus and related diseasesGenomics and Chromatin Dynamics

Cited by 761

Differential Control of Learning and Anxiety along the Dorsoventral Axis of the Dentate Gyrus

Kheirbek, M. A., Drew, L. J., Burghardt, N. S., Costantini, D. O., Tannenholz, L., Ahmari, S. E., Zeng, H., Fenton, A. A., & Hen, R. (2013) · Neuron

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 713

Antidepressants increase neural progenitor cells in the human hippocampus

Boldrini, M., Underwood, M. D., Hen, R., Rosoklija, G. B., Dwork, A. J., John Mann, J., & Arango, V. (2009) · Neuropsychopharmacology

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 686

Hippocampal Neurogenesis: Regulation by Stress and Antidepressants

Dranovsky, A., & Hen, R. (2006) · Biological Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 663

Hippocampal neurogenesis confers stress resilience by inhibiting the ventral dentate gyrus

Anacker, C., Luna, V. M., Stevens, G. S., Millette, A., Shores, R., Jimenez, J. C., Chen, B., & Hen, R. (2018) · Nature

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 605

Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like Behaviors

Hill, A. S., Sahay, A., & Hen, R. (2015) · Neuropsychopharmacology

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 557

Drug-dependent requirement of hippocampal neurogenesis in a model of depression and of antidepressant reversal

Surget, A., Saxe, M., Leman, S., Ibarguen-Vargas, Y., Chalon, S., Griebel, G., Hen, R., & Belzung, C. (2008) · Biological Psychiatry

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 556

Chronic fluoxetine stimulates maturation and synaptic plasticity of adult-born hippocampal granule cells

Wang, J.-W., David, D. J., Monckton, J. E., Battaglia, F., & Hen, R. (2008) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 550

Pattern separation: a common function for new neurons in hippocampus and olfactory bulb

Sahay, A., Wilson, D. A., & Hen, R. (2011) · Neuron

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 514

Dendritic Inhibition in the Hippocampus Supports Fear Learning

Lovett-Barron, M., Kaifosh, P., Kheirbek, M. A., Danielson, N., Zaremba, J. D., Reardon, T. R., Turi, G. F., Hen, R., Zemelman, B. V., & Losonczy, A. (2014) · Science

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 509

Repeated cortico-striatal stimulation generates persistent OCD-like behavior

Ahmari, S. E., Spellman, T., Douglass, N. L., Kheirbek, M. A., Simpson, H. B., Deisseroth, K., Gordon, J. A., & Hen, R. (2013) · Science

Obsessive-Compulsive Spectrum DisordersDeep Brain Stimulation and Movement Disorders

Cited by 502

Antidepressants recruit new neurons to improve stress response regulation

Surget, A., Tanti, A., Leonardo, E. D., Laugeray, A., Rainer, Q., Touma, C., Palme, R., Griebel, G., Ibarguen-Vargas, Y., Hen, R., et al. (2011) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 471

5-HT1A autoreceptor levels determine vulnerability to stress and response to antidepressants

Richardson-Jones, J. W., Craige, C. P., Guiard, B. P., Stephen, A., Metzger, K. L., Kung, H. F., Gardier, A. M., Dranovsky, A., David, D. J., Beck, S. G., et al. (2010) · Neuron

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 450

The current state of the neurogenic theory of depression and anxiety

Miller, B. R., & Hen, R. (2015) · Current Opinion in Neurobiology

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 386

Fear erasure in mice requires synergy between antidepressant drugs and extinction training

Karpova, N. N., Pickenhagen, A., Lindholm, J., Tiraboschi, E., Kulesskaya, N., Ágústsdóttir, A., Antila, H., Popova, D., Akamine, Y., Sullivan, R., et al. (2011) · Science

Memory and Neural MechanismsNeurotransmitter Receptor Influence on Behavior

Cited by 382

Hippocampal granule neuron number and dentate gyrus volume in antidepressant-treated and untreated major depression

Boldrini, M., Santiago, A. N., Hen, R., Dwork, A. J., Rosoklija, G. B., Tamir, H., Arango, V., & John Mann, J. (2013) · Neuropsychopharmacology

Treatment of Major DepressionStress Responses and Cortisol

Cited by 361

Distinct contribution of adult-born hippocampal granule cells to context encoding

Danielson, N. B., Kaifosh, P., Zaremba, J. D., Lovett-Barron, M., Tsai, J., Denny, C. A., Balough, E. M., Goldberg, A. R., Drew, L. J., Hen, R., et al. (2016) · Neuron

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 352

Hippocampal Angiogenesis and Progenitor Cell Proliferation Are Increased with Antidepressant Use in Major Depression

Boldrini, M., Hen, R., Underwood, M. D., Rosoklija, G. B., Dwork, A. J., Mann, J. J., & Arango, V. (2012) · Biological Psychiatry

Neurogenesis and neuroplasticity mechanismsTreatment of Major Depression

Cited by 348

Adult‐born hippocampal neurons promote cognitive flexibility in mice

Burghardt, N. S., Park, E. H., Hen, R., & Fenton, A. A. (2012) · Hippocampus

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 311