Medzhitov, Ruslan

Innate immune recognition

Janeway, C. A., & Medzhitov, R. (2002) · Annual Review of Immunology

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 8,394

Origin and physiological roles of inflammation

Medzhitov, R. (2008) · Nature

Immune Response and InflammationInflammation biomarkers and pathways

Cited by 6,618

Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3

Alexopoulou, L., Holt, A. C., Medzhitov, R., & Flavell, R. A. (2001) · Nature

Immune Response and InflammationNF-κB Signaling Pathways

Cited by 6,129

Toll-like receptors and innate immunity

Medzhitov, R. (2001) · Nature Reviews Immunology

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 4,308

Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis

Rakoff-Nahoum, S., Paglino, J., Eslami-Varzaneh, F., Edberg, S., & Medzhitov, R. (2004) · Cell

Immune Response and InflammationGut microbiota and health

Cited by 4,251

Functional Polarization of Tumour-Associated Macrophages by Tumour-Derived Lactic Acid

Colegio, O. R., Chu, N.-Q., Szabo, A. L., Chu, T., Rhebergen, A. M., Jairam, V., Cyrus, N., Brokowski, C. E., Eisenbarth, S. C., Phillips, G. M., et al. (2014) · Nature

Immune cells in cancerCancer, Hypoxia, and Metabolism

Cited by 3,046

Recognition of microorganisms and activation of the immune response

Medzhitov, R. (2007) · Nature

Immune Response and InflammationImmune responses and vaccinations

Cited by 2,862

Innate Immunity: The Virtues of a Nonclonal System of Recognition

Medzhitov, R., & Janeway, C. A. (1997) · Cell

Immune Response and InflammationInvertebrate Immune Response Mechanisms

Cited by 2,434

The microbial metabolite butyrate regulates intestinal macrophage function via histone deacetylase inhibition.

Chang, P. V., Hao, L., Offermanns, S., & Medzhitov, R. (2014) · Proceedings of the National Academy of Sciences

Gut microbiota and healthInflammatory Bowel Disease

Cited by 2,175

Control of adaptive immunity by the innate immune system

Iwasaki, A., & Medzhitov, R. (2015) · Nature Immunology

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 2,160

Decoding the Patterns of Self and Nonself by the Innate Immune System

Medzhitov, R., & Janeway, C. A. (2002) · Science

Immune Response and InflammationInvertebrate Immune Response Mechanisms

Cited by 2,154

Longitudinal analyses reveal immunological misfiring in severe COVID-19

Lucas, C., Wong, P., Klein, J., Castro, T. B. R., Silva, J., Sundaram, M., Ellingson, M. K., Mao, T., Oh, J. E., Israelow, B., et al. (2020) · Nature

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 2,074

Disease Tolerance as a Defense Strategy

Medzhitov, R., Schneider, D. S., & Soares, M. P. (2012) · Science

Immune Response and InflammationImmune responses and vaccinations

Cited by 1,718

Regulation of lung injury and repair by Toll-like receptors and hyaluronan

Jiang, D., Liang, J., Fan, J., Yu, S., Chen, S., Luo, Y., Prestwich, G. D., Mascarenhas, M. M., Garg, H. G., Quinn, D. A., et al. (2005) · Nature Medicine

Proteoglycans and glycosaminoglycans researchImmune Response and Inflammation

Cited by 1,401

Gene-specific control of inflammation by TLR-induced chromatin modifications

Foster, S. L., Hargreaves, D. C., & Medzhitov, R. (2007) · Nature

Immune Response and InflammationGenomics and Chromatin Dynamics

Cited by 1,344

Trex1 prevents cell-intrinsic initiation of autoimmunity

Stetson, D. B., Ko, J. S., Heidmann, T., & Medzhitov, R. (2008) · Cell

interferon and immune responsesSystemic Lupus Erythematosus Research

Cited by 1,280

Homeostasis, Inflammation, and Disease Susceptibility

Kotas, M. E., & Medzhitov, R. (2015) · Cell

Adipokines, Inflammation, and Metabolic DiseasesImmune Response and Inflammation

Cited by 1,213

Transcriptional control of the inflammatory response

Medzhitov, R., & Horng, T. (2009) · Nature Reviews Immunology

Immune Response and InflammationGenomics and Chromatin Dynamics

Cited by 1,035

Regulation of Phagosome Maturation by Signals from Toll-Like Receptors

Blander, J. M., & Medzhitov, R. (2004) · Science

Immune Response and InflammationPhagocytosis and Immune Regulation

Cited by 991

Harnessing innate immunity in cancer therapy

Demaria, O., Cornen, S., Daëron, M., Morel, Y., Medzhitov, R., & Vivier, E. (2019) · Nature

Immunotherapy and Immune ResponsesImmune cells in cancer

Cited by 957

Toll-like receptors and cancer

Rakoff-Nahoum, S., & Medzhitov, R. (2009) · Nature Reviews Cancer

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 925

Tissue-specific signals control reversible program of localization and functional polarization of macrophages

Okabe, Y., & Medzhitov, R. (2014) · Cell

Immune cells in cancerT-cell and B-cell Immunology

Cited by 884

The spectrum of inflammatory responses

Medzhitov, R. (2021) · Science

Immune Response and InflammationInflammation biomarkers and pathways

Cited by 718

Stress, Inflammation, and Defense of Homeostasis

Chovatiya, R., & Medzhitov, R. (2014) · Molecular Cell

Immune Response and InflammationInflammasome and immune disorders

Cited by 704