Suderman, Matthew

Single-nucleus transcriptomics of the prefrontal cortex in major depressive disorder implicates oligodendrocyte precursor cells and excitatory neurons

Nagy, C., Maitra, M., Tanti, A., Suderman, M., Théroux, J.-F., Davoli, M. A., Perlman, K., Yerko, V., Wang, Y. C., Tripathy, S. J., et al. (2020) · Nature Neuroscience

Treatment of Major DepressionSingle-cell and spatial transcriptomics

Cited by 532

Single-nucleus RNA sequencing shows convergent evidence from different cell types for altered synaptic plasticity in major depressive disorder

Nagy, C., Maitra, M., Tanti, A., Suderman, M., Théroux, J.-F., Mechawar, N., Ragoussis, J., & Turecki, G. (2018) · Nature Neuroscience

Treatment of Major DepressionSingle-cell and spatial transcriptomics

Cited by 523

Disruption of histone methylation in developing sperm impairs offspring health transgenerationally

Siklenka, K., Erkek, S., Godmann, M., Lambrot, R., McGraw, S., Lafleur, C., Cohen, T., Xia, J., Suderman, M., Hallett, M., et al. (2015) · Science

Epigenetics and DNA MethylationSperm and Testicular Function

Cited by 521

Genomic and phenotypic insights from an atlas of genetic effects on DNA methylation

Min, J. L., Hemani, G., Hannon, E., Dekkers, K. F., Castillo-Fernandez, J., Luijk, R., Carnero-Montoro, E., Lawson, D. J., Burrows, K., Suderman, M., et al. (2021) · Nature Genetics

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 506

Broad Epigenetic Signature of Maternal Care in the Brain of Adult Rats

McGowan, P. O., Suderman, M., Sasaki, A., Huang, T. C. T., Hallett, M., Meaney, M. J., & Szyf, M. (2011) · PLoS ONE

Epigenetics and DNA MethylationNeuroendocrine regulation and behavior

Cited by 452

Conserved epigenetic sensitivity to early life experience in the rat and human hippocampus

Suderman, M., McGowan, P. O., Sasaki, A., Huang, T. C. T., Hallett, M. T., Meaney, M. J., Turecki, G., & Szyf, M. (2012) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationStress Responses and Cortisol

Cited by 327

DNA Methylation Signatures Triggered by Prenatal Maternal Stress Exposure to a Natural Disaster: Project Ice Storm

Cao-Lei, L., Massart, R., Suderman, M. J., Machnes, Z., Elgbeili, G., Laplante, D. P., Szyf, M., & King, S. (2014) · PLoS ONE

Epigenetics and DNA MethylationMaternal Mental Health During Pregnancy and Postpartum

Cited by 321

Sensitive periods for the effect of childhood adversity on DNA methylation: results from a prospective, longitudinal study

Dunn, E. C., Soare, T. W., Zhu, Y., Simpkin, A. J., Suderman, M. J., Klengel, T., Smith, A. D. A. C., Ressler, K. J., & Relton, C. L. (2019) · Biological Psychiatry

Epigenetics and DNA MethylationChild Abuse and Trauma

Cited by 315

The signature of maternal rearing in the methylome in rhesus macaque prefrontal cortex and T cells

Provençal, N., Suderman, M. J., Guillemin, C., Massart, R., Ruggiero, A., Wang, D., Bennett, A. J., Pierre, P. J., Friedman, D. P., Côté, S. M., et al. (2012) · The Journal of Neuroscience

Epigenetics and DNA MethylationChild Abuse and Trauma

Cited by 312

Astrocytic abnormalities and global DNA methylation patterns in depression and suicide

Nagy, C., Suderman, M., Yang, J., Szyf, M., Mechawar, N., Ernst, C., & Turecki, G. (2015) · Molecular Psychiatry

Epigenetics and DNA MethylationTreatment of Major Depression

Cited by 301

Prenatal and early life influences on epigenetic age in children: A study of mother–offspring pairs from two cohort studies

Simpkin, A. J., Hemani, G., Suderman, M., Gaunt, T. R., Lyttleton, O., Mcardle, W. L., Ring, S. M., Sharp, G. C., Tilling, K., Horvath, S., et al. (2016) · Human Molecular Genetics

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 246

Childhood abuse is associated with methylation of multiple loci in adult DNA

Suderman, M., Borghol, N., Pappas, J. J., Pinto Pereira, S. M., Pembrey, M., Hertzman, C., Power, C., & Szyf, M. (2014) · BMC Medical Genomics

Epigenetics and DNA MethylationChild Abuse and Trauma

Cited by 193

Epigenome-wide change and variation in DNA methylation in childhood: trajectories from birth to late adolescence

Mulder, R. H., Neumann, A., Cecil, C. A. M., Walton, E., Houtepen, L. C., Simpkin, A. J., Rijlaarsdam, J., Heijmans, B. T., Gaunt, T. R., Felix, J. F., et al. (2021) · Human Molecular Genetics

Epigenetics and DNA MethylationBirth, Development, and Health

Cited by 165

Glucocorticoid programming of the fetal male hippocampal epigenome

Crudo, A., Suderman, M., Moisiadis, V. G., Petropoulos, S., Kostaki, A., Hallett, M., Szyf, M., & Matthews, S. G. (2013) · Endocrinology

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 123

dmrff: identifying differentially methylated regions efficiently with power and control

Suderman, M., Staley, J. R., French, R., Arathimos, R., Simpkin, A., & Tilling, K. (2018) · bioRxiv (Cold Spring Harbor Laboratory)

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 120

DNA methylation and substance-use risk: a prospective, genome-wide study spanning gestation to adolescence

Cecil, C. A. M., Walton, E., Smith, R. G., Viding, E., McCrory, E. J., Relton, C. L., Suderman, M., Pingault, J.-B., McArdle, W., Gaunt, T. R., et al. (2016) · Translational Psychiatry

Epigenetics and DNA MethylationGenetic Associations and Epidemiology

Cited by 101

Association of Childhood Chronic Physical Aggression with a DNA Methylation Signature in Adult Human T Cells

Provençal, N., Suderman, M. J., Guillemin, C., Vitaro, F., Côté, S. M., Hallett, M., Tremblay, R. E., & Szyf, M. (2014) · PLoS ONE

Epigenetics and DNA MethylationChild Abuse and Trauma

Cited by 85

Effects of antenatal synthetic glucocorticoid on glucocorticoid receptor binding, DNA methylation, and genome-wide mRNA levels in the fetal male hippocampus

Crudo, A., Petropoulos, S., Suderman, M., Moisiadis, V. G., Kostaki, A., Hallett, M., Szyf, M., & Matthews, S. G. (2013) · Endocrinology

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 73

Use of correct and incorrect methods of accounting for age in studies of epigenetic accelerated aging: Implications and recommendations for best practices

Krieger, N., Chen, J. T., Testa, C., Diez Roux, A., Tilling, K., Watkins, S., Simpkin, A. J., Suderman, M., Davey Smith, G., De Vivo, I., et al. (2023) · American Journal of Epidemiology

Epigenetics and DNA MethylationStatistical Methods in Epidemiology

Cited by 52

Extraction of nuclei from archived postmortem tissues for single-nucleus sequencing applications

Maitra, M., Nagy, C., Chawla, A., Wang, Y. C., Nascimento, C., Suderman, M., Théroux, J.-F., Mechawar, N., Ragoussis, J., & Turecki, G. (2021) · Nature Protocols

Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies

Cited by 42

Investigating evidence for a causal association between inflammation and self-harm: A multivariable Mendelian Randomisation study

Russell, A. E., Ford, T., Gunnell, D., Heron, J., Joinson, C., Moran, P., Relton, C., Suderman, M., Hemani, G., & Mars, B. (2020) · Brain, Behavior, and Immunity

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 39

Associations between epigenetic aging and childhood peer victimization, depression, and suicidal ideation in adolescence and adulthood: a study of two population-based samples

Perret, L. C., Geoffroy, M.-C., Barr, E., Parnet, F., Provencal, N., Boivin, M., O’Donnell, K. J., Suderman, M., Power, C., Turecki, G., et al. (2023) · Frontiers in Cell and Developmental Biology

Epigenetics and DNA MethylationBullying, Victimization, and Aggression

Cited by 19