Bonewald, Lynda F.

The amazing osteocyte

Bonewald, L. F. (2011) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 2,287

Evidence for osteocyte regulation of bone homeostasis through RANKL expression

Nakashima, T., Hayashi, M., Fukunaga, T., Kurata, K., Oh-hora, M., Feng, J. Q., Bonewald, L. F., Kodama, T., Wutz, A., Wagner, E. F., et al. (2011) · Nature Medicine

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 1,778

Loss of DMP1 causes rickets and osteomalacia and identifies a role for osteocytes in mineral metabolism

Feng, J. Q., Ward, L. M., Liu, S., Lu, Y., Xie, Y., Yuan, B., Yu, X., Rauch, F., Davis, S. I., Zhang, S., et al. (2006) · Nature Genetics

Parathyroid Disorders and TreatmentsAlkaline Phosphatase Research Studies

Cited by 1,199

Osteocytes, mechanosensing and Wnt signaling

Bonewald, L. F., & Johnson, M. L. (2008) · Bone

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 1,076

The Osteocyte: An Endocrine Cell … and More

Dallas, S. L., Prideaux, M., & Bonewald, L. F. (2013) · Endocrine Reviews

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 1,042

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors

Kim, H., Wrann, C. D., Jedrychowski, M., Vidoni, S., Kitase, Y., Nagano, K., Zhou, C., Chou, J., Parkman, V.-J. A., Novick, S. J., et al. (2018) · Cell

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 638

Identification of senescent cells in the bone microenvironment

Farr, J. N., Fraser, D. G., Wang, H., Jaehn, K., Ogrodnik, M. B., Weivoda, M. M., Drake, M. T., Tchkonia, T., LeBrasseur, N. K., Kirkland, J. L., et al. (2016) · Journal of Bone and Mineral Research

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 562

The Osteocyte: New Insights

Robling, A. G., & Bonewald, L. F. (2020) · Annual Review of Physiology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 539

Sclerostin Stimulates Osteocyte Support of Osteoclast Activity by a RANKL-Dependent Pathway

Wijenayaka, A. R., Kogawa, M., Lim, H. P., Bonewald, L. F., Findlay, D. M., & Atkins, G. J. (2011) · PLoS ONE

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 503

Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation

Qing, H., Ardeshirpour, L., Divieti Pajevic, P., Dusevich, V., Jähn, K., Kato, S., Wysolmerski, J., & Bonewald, L. F. (2012) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 489

Mechanical Strain Opens Connexin 43 Hemichannels in Osteocytes: A Novel Mechanism for the Release of Prostaglandin

Cherian, P. P., Siller-Jackson, A. J., Gu, S., Wang, X., Bonewald, L. F., Sprague, E., & Jiang, J. X. (2005) · Molecular Biology of the Cell

Connexins and lens biologyCellular Mechanics and Interactions

Cited by 481

Glucocorticoid-treated mice have localized changes in trabecular bone material properties and osteocyte lacunar size that are not observed in placebo-treated or estrogen-deficient mice

Lane, N. E., Yao, W., Balooch, M., Nalla, R. K., Balooch, G., Habelitz, S., Kinney, J. H., & Bonewald, L. F. (2006) · Journal of Bone and Mineral Research

Bone health and osteoporosis researchBone Metabolism and Diseases

Cited by 355

Osteocytes, not Osteoblasts or Lining Cells, are the Main Source of the RANKL Required for Osteoclast Formation in Remodeling Bone

Xiong, J., Piemontese, M., Onal, M., Campbell, J., Goellner, J. J., Dusevich, V., Bonewald, L., Manolagas, S. C., & O’Brien, C. A. (2015) · PLOS ONE

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 323

MLO-Y4 Osteocyte-Like Cells Support Osteoclast Formation and Activation

Zhao, S., Kato, Y., Zhang, Y., Harris, S., Ahuja, S. S., & Bonewald, L. F. (2002) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 322

Cilia-like Structures and Polycystin-1 in Osteoblasts/Osteocytes and Associated Abnormalities in Skeletogenesis and Runx2 Expression

Xiao, Z., Zhang, S., Mahlios, J., Zhou, G., Magenheimer, B. S., Guo, D., Dallas, S. L., Maser, R., Calvet, J. P., Bonewald, L., et al. (2006) · Journal of Biological Chemistry

Genetic and Kidney Cyst DiseasesBone Metabolism and Diseases

Cited by 254

Cell line IDG-SW3 replicates osteoblast-to-late-osteocyte differentiation in vitro and accelerates bone formation in vivo

Woo, S. M., Rosser, J., Dusevich, V., Kalajzic, I., & Bonewald, L. F. (2011) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesBone Tissue Engineering Materials

Cited by 243

β-aminoisobutyric Acid, l-BAIBA, Is a Muscle-Derived Osteocyte Survival Factor

Kitase, Y., Vallejo, J. A., Gutheil, W., Vemula, H., Jähn, K., Yi, J., Zhou, J., Brotto, M., & Bonewald, L. F. (2018) · Cell Reports

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 219

Glucocorticoid induced autophagy in osteocytes

Xia, X., Kar, R., Gluhak-Heinrich, J., Yao, W., Lane, N. E., Bonewald, L. F., Biswas, S. K., Lo, W.-K., & Jiang, J. X. (2010) · Journal of Bone and Mineral Research

Autophagy in Disease and TherapyBone Metabolism and Diseases

Cited by 193

Mechanically induced Ca2+ oscillations in osteocytes release extracellular vesicles and enhance bone formation

Morrell, A. E., Brown, G. N., Robinson, S. T., Sattler, R. L., Baik, A. D., Zhen, G., Cao, X., Bonewald, L. F., Jin, W., Kam, L. C., et al. (2018) · Bone Research

Bone Metabolism and DiseasesExtracellular vesicles in disease

Cited by 184

Degeneration of the osteocyte network in the C57BL/6 mouse model of aging

Tiede-Lewis, L. M., Xie, Y., Hulbert, M. A., Campos, R., Dallas, M. R., Dusevich, V., Bonewald, L. F., & Dallas, S. L. (2017) · Aging

Bone health and osteoporosis researchBone Metabolism and Diseases

Cited by 176

Glucocorticoid dose determines osteocyte cell fate

Jia, J., Yao, W., Guan, M., Dai, W., Shahnazari, M., Kar, R., Bonewald, L., Jiang, J. X., & Lane, N. E. (2011) · The FASEB Journal

Bone Metabolism and DiseasesAutophagy in Disease and Therapy

Cited by 157

Exendin-4 increases bone mineral density in type 2 diabetic OLETF rats potentially through the down-regulation of SOST/sclerostin in osteocytes

Kim, J.-Y., Lee, S.-K., Jo, K.-J., Song, D.-Y., Lim, D.-M., Park, K.-Y., Bonewald, L. F., & Kim, B.-J. (2013) · Life Sciences

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 137

The Osteoblast to Osteocyte Transition: Epigenetic Changes and Response to the Vitamin D3Hormone

St. John, H. C., Bishop, K. A., Meyer, M. B., Benkusky, N. A., Leng, N., Kendziorski, C., Bonewald, L. F., & Pike, J. W. (2014) · Molecular Endocrinology

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 127

Osteocytes Acidify Their Microenvironment in Response to PTHrP In Vitro and in Lactating Mice In Vivo

Jähn, K., Kelkar, S., Zhao, H., Xie, Y., Tiede-Lewis, L. M., Dusevich, V., Dallas, S. L., & Bonewald, L. F. (2017) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesBone health and osteoporosis research

Cited by 116