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Connexin 43 hemichannels mediate the Ca2+ influx induced by extracellular alkalinization

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In vitro and in vivo approaches to study osteocyte biology

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Gap junctions and hemichannels in signal transmission, function and development of bone

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From streaming‐potentials to shear stress: 25 years of bone cell mechanotransduction

Riddle, R. C., & Donahue, H. J. (2009) · Journal of Orthopaedic Research · doi:10.1002/jor.20723 · Cited by 157 · see citing works

Beyond gap junctions: Connexin43 and bone cell signaling

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Pannexins, distant relatives of the connexin family with specific cellular functions?

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Gap junctions in skeletal development and function

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Activation of β-catenin signaling in MLO-Y4 osteocytic cells versus 2T3 osteoblastic cells by fluid flow shear stress and PGE2: Implications for the study of mechanosensation in bone

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The roles of exercise in bone remodeling and in prevention and treatment of osteoporosis

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Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling

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Roles of gap junctions and hemichannels in bone cell functions and in signal transmission of mechanical stress

Jiang, J. X. (2006) · Frontiers in bioscience · doi:10.2741/2159 · Cited by 140 · see citing works

Mechanical motion promotes expression of Prg4 in articular cartilage via multiple CREB-dependent, fluid flow shear stress-induced signaling pathwaysPreprint

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Articular chondrocytes express connexin 43 hemichannels and P2 receptors – a putative mechanoreceptor complex involving the primary cilium?

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Biomechanics of Cardiac Electromechanical Coupling and Mechanoelectric Feedback

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The Role of the Osteocyte in Bone and Nonbone Disease

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Osteocytes and WNT: the Mechanical Control of Bone Formation

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The role of connexins in ear and skin physiology — Functional insights from disease-associated mutations

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Irisin Prevents Disuse-Induced Osteocyte Apoptosis

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The Mechanosensory Role of Osteocytes and Implications for Bone Health and Disease States

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Skeletal muscle secreted factors prevent glucocorticoid-induced osteocyte apoptosis through activation of β-catenin

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Attenuated Response to In Vivo Mechanical Loading in Mice With Conditional Osteoblast Ablation of the Connexin43 Gene (Gja1)

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Roles of gap junctions, connexins, and pannexins in epilepsy

Mylvaganam, S., Ramani, M., Krawczyk, M., & Carlen, P. L. (2014) · Frontiers in Physiology · doi:10.3389/fphys.2014.00172 · Cited by 112 · see citing works

Functions of the osteocyte network in the regulation of bone mass

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Mechanotransduction in osteogenesis

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Connexin 43 Channels Are Essential for Normal Bone Structure and Osteocyte Viability

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Long-Chain Polyunsaturated Fatty Acids and the Regulation of Bone Metabolism

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Osteocytic connexin hemichannels suppress breast cancer growth and bone metastasis

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Gap junction and hemichannel functions in osteocytes

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ATP Release Mediates Fluid Flow–Induced Proliferation of Human Bone Marrow Stromal Cells

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Responsiveness of human bone marrow stromal cells to shear stress

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Hemichannels: New pathways for gliotransmitter release

Montero, T. D., & Orellana, J. A. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2014.11.048 · Cited by 94 · see citing works

Deletion of Connexin43 in Osteoblasts/Osteocytes Leads to Impaired Muscle Formation in Mice

Shen, H., Grimston, S. K., Civitelli, R., & Thomopoulos, S. (2014) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.2389 · Cited by 94 · see citing works

Sost down‐regulation by mechanical strain in human osteoblastic cells involves PGE2 signaling via EP4

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Diseases associated with leaky hemichannels

Retamal, M. A., Reyes, E. P., García, I. E., Pinto, B. I., Martínez, A. D., & González, C. (2015) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2015.00267 · Cited by 92 · see citing works

Pericyte mechanics and mechanobiology

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Effects of cyclic hydraulic pressure on osteocytes

Liu, C., Zhao, Y., Cheung, W.-Y., Gandhi, R., Wang, L., & You, L. (2010) · Bone · doi:10.1016/j.bone.2010.02.006 · Cited by 88 · see citing works

Signaling networks and transcription factors regulating mechanotransduction in bone

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Direct Regulation of Osteocytic Connexin 43 Hemichannels through AKT Kinase Activated by Mechanical Stimulation

Batra, N. R., Riquelme, M. A., Burra, S., Kar, R., Gu, S., & Jiang, J. X. (2014) · Journal of Biological Chemistry · doi:10.1074/jbc.m114.550608 · Cited by 88 · see citing works

Currently Used Methods for Identification and Characterization of Hemichannels

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Differential expression of connexins in trigeminal ganglion neurons and satellite glial cells in response to chronic or acute joint inflammation

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Trabecular bone organoids: a micron-scale ‘humanised’ prototype designed to study the effects of microgravity and degeneration

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Glial hemichannels and their involvement in aging and neurodegenerative diseases

Orellana, J. A., Rommy von Bernhardi, M., Giaume, C., & Sáez, J. C. (2012) · Reviews in the Neurosciences · doi:10.1515/revneuro-2011-0065 · Cited by 86 · see citing works

Enteric glial activity regulates secretomotor function in the mouse colon but does not acutely affect gut permeability

Grubišić, V., & Gulbransen, B. D. (2017) · The Journal of Physiology · doi:10.1113/jp273492 · Cited by 87 · see citing works

Connexins and pannexins: At the junction of neuro‐glial homeostasis & disease

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Cancer Connectors: Connexins, Gap Junctions, and Communication

Sinyuk, M., Mulkearns-Hubert, E. E., Reizes, O., & Lathia, J. D. (2018) · Frontiers in Oncology · doi:10.3389/fonc.2018.00646 · Cited by 85 · see citing works

Gap junction channels and hemichannels in the CNS: Regulation by signaling molecules

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Hemichannels Formed by Connexin 43 Play an Important Role in the Release of Prostaglandin E2 by Osteocytes in Response to Mechanical Strain

Jiang, J. X., & Cherian, P. P. (2003) · Cell Communication & Adhesion · doi:10.1080/cac.10.4-6.259.264 · Cited by 92 · see citing works

Connexin 43 hemichannel opening associated with Prostaglandin E 2 release is adaptively regulated by mechanical stimulation

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Adaptation of Connexin 43-Hemichannel Prostaglandin Release to Mechanical Loading

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Half-Gap Junctions Mediating Prostaglandin Release

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Connexin 43 hemichannels and prostaglandin E2 release in anabolic function of the skeletal tissue to mechanical stimulation

Zhao, D., Wu, J., Acosta, F. M., Xu, H., & Jiang, J. X. (2023) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2023.1151838 · Cited by 20 · see citing works