Brooks, David J.

Microglial activation in presymptomatic Huntington's disease gene carriers

Tai, Y. F., Pavese, N., Gerhard, A., Tabrizi, S. J., Barker, R. A., Brooks, D. J., & Piccini, P. (2007) · Brain

Genetic Neurodegenerative DiseasesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 440

Validation of the freezing of gait questionnaire in patients with Parkinson’s disease

Giladi, N., Tal, J., Azulay, T., Rascol, O., Brooks, D. J., Melamed, E., Oertel, W., Poewe, W. H., Stocchi, F., & Tolosa, E. (2009) · Movement Disorders

Balance, Gait, and Falls PreventionParkinson's Disease Mechanisms and Treatments

Cited by 431

Accuracy of Brain Amyloid Detection in Clinical Practice Using Cerebrospinal Fluid β-Amyloid 42: A Cross-Validation Study Against Amyloid Positron Emission Tomography

Palmqvist, S., Zetterberg, H., Blennow, K., Vestberg, S., Andreasson, U., Brooks, D. J., Owenius, R., Hägerström, D., Wollmer, P., Minthon, L., et al. (2014) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 368

Microglial activation and amyloid deposition in mild cognitive impairment: A PET study

Okello, A., Edison, P., Archer, H. A., Turkheimer, F. E., Kennedy, J., Bullock, R., Walker, Z., Kennedy, A., Fox, N., Rossor, M., et al. (2009) · Neurology

Dementia and Cognitive Impairment ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 367

In-vivo staging of pathology in REM sleep behaviour disorder: A multimodality imaging case-control study

Knudsen, K., Fedorova, T. D., Hansen, A. K., Sommerauer, M., Otto, M., Svendsen, K. B., Nahimi, A., Stokholm, M. G., Pavese, N., Beier, C. P., et al. (2018) · The Lancet Neurology

Parkinson's Disease Mechanisms and TreatmentsDementia and Cognitive Impairment Research

Cited by 309

Prevalence Estimates of Amyloid Abnormality Across the Alzheimer Disease Clinical Spectrum

Jansen, W. J., Janssen, O., Tijms, B. M., Vos, S. J. B., Ossenkoppele, R., Visser, P. J., Amyloid Biomarker Study Group, Aarsland, D., Alcolea, D., Altomare, D., et al. (2022) · JAMA Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 290

Microglial activation correlates in vivo with both tau and amyloid in Alzheimer’s disease

Dani, M., Wood, M., Mizoguchi, R., Fan, Z., Walker, Z., Morgan, R., Hinz, R., Biju, M., Kuruvilla, T., Brooks, D. J., et al. (2018) · Brain

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 270

[ 11 C] (R)-PK11195 positron emission tomography imaging of activated microglia in vivo in Rasmussen’s encephalitis

Banati, R. B., Goerres, G. W., Myers, R., Gunn, R. N., Turkheimer, F. E., Kreutzberg, G. W., Brooks, D. J., Jones, T., & Duncan, J. S. (1999) · Neurology

Neuroinflammation and Neurodegeneration MechanismsMedical Imaging Techniques and Applications

Cited by 224

Depression in Parkinson's Disease: A Positron Emission Study

Ring, H. A., Bench, C. J., Trimble, M. R., Brooks, D. J., Frackowiak, R. S. J., & Dolan, R. J. (1994) · British Journal of Psychiatry

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 219

Influence of microglial activation on neuronal function in Alzheimer's and Parkinson's disease dementia

Fan, Z., Aman, Y., Ahmed, I., Chetelat, G., Landeau, B., Ray Chaudhuri, K., Brooks, D. J., & Edison, P. (2015) · Alzheimer's & Dementia

Neuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research

Cited by 212

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: a multimodal imaging study

Politis, M., Pavese, N., Tai, Y. F., Kiferle, L., Mason, S. L., Brooks, D. J., Tabrizi, S. J., Barker, R. A., & Piccini, P. (2011) · Human Brain Mapping

Genetic Neurodegenerative DiseasesNeurological diseases and metabolism

Cited by 212

Brain inflammation accompanies amyloid in the majority of mild cognitive impairment cases due to Alzheimer's disease

Parbo, P., Ismail, R., Hansen, K. V., Amidi, A., Mårup, F. H., Gottrup, H., Brændgaard, H., Eriksson, B. O., Eskildsen, S. F., Lund, T. E., et al. (2017) · Brain

Dementia and Cognitive Impairment ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 199

A European multicentre PET study of fibrillar amyloid in Alzheimer’s disease

Nordberg, A., Carter, S. F., Rinne, J., Drzezga, A., Brooks, D. J., Vandenberghe, R., Perani, D., Forsberg, A., Långström, B., Scheinin, N., et al. (2013) · European Journal of Nuclear Medicine and Molecular Imaging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 186

In vivo imaging of microglial activation with [11C](R)‐PK11195 PET in progressive supranuclear palsy

Gerhard, A., Trender‐Gerhard, I., Turkheimer, F., Quinn, N. P., Bhatia, K. P., & Brooks, D. J. (2006) · Movement Disorders

Neuroinflammation and Neurodegeneration MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 171

Progression of monoaminergic dysfunction in parkinson's disease: a longitudinal 18f-dopa pet study

Pavese, N., Rivero-Bosch, M., Lewis, S. J., Whone, A. L., & Brooks, D. J. (2011) · NeuroImage

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 145

Longitudinal influence of microglial activation and amyloid on neuronal function in Alzheimer’s disease

Fan, Z., Okello, A. A., Brooks, D. J., & Edison, P. (2015) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 135

The Role of Neuroinflammation in Dementias

Pasqualetti, G., Brooks, D. J., & Edison, P. (2015) · Current Neurology and Neuroscience Reports

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 133

In vivo imaging of neuromelanin in Parkinson’s disease using18F-AV-1451 PET

Hansen, A. K., Knudsen, K., Lillethorup, T. P., Landau, A. M., Parbo, P., Fedorova, T., Audrain, H., Bender, D., Østergaard, K., Brooks, D. J., et al. (2016) · Brain

Parkinson's Disease Mechanisms and TreatmentsMedical Imaging Techniques and Applications

Cited by 128

Motor and Nonmotor Complications of Levodopa: Phenomenology, Risk Factors, and Imaging Features

Ray Chaudhuri, K., Poewe, W., & Brooks, D. (2018) · Movement Disorders

Parkinson's Disease Mechanisms and TreatmentsDeep Brain Stimulation and Movement Disorders

Cited by 121

Dynamic 11 C-PiB PET Shows Cerebrospinal Fluid Flow Alterations in Alzheimer Disease and Multiple Sclerosis

Schubert, J. J., Veronese, M., Marchitelli, L., Bodini, B., Tonietto, M., Stankoff, B., Brooks, D. J., Bertoldo, A., Edison, P., & Turkheimer, F. E. (2019) · Journal of Nuclear Medicine

Cerebrospinal fluid and hydrocephalusDementia and Cognitive Impairment Research

Cited by 121

Widespread cell stress and mitochondrial dysfunction occur in patients with early Alzheimer’s disease

Venkataraman, A. V., Mansur, A., Rizzo, G., Bishop, C., Lewis, Y., Kocagoncu, E., Lingford-Hughes, A., Huiban, M., Passchier, J., Rowe, J. B., et al. (2022) · Science Translational Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 101

Novel Reference Region Model Reveals Increased Microglial and Reduced Vascular Binding of 11C-(R)-PK11195 in Patients with Alzheimer's Disease

Tomasi, G., Edison, P., Bertoldo, A., Roncaroli, F., Singh, P., Gerhard, A., Cobelli, C., Brooks, D. J., & Turkheimer, F. E. (2008) · Journal of Nuclear Medicine

Neuroinflammation and Neurodegeneration MechanismsMedical Imaging Techniques and Applications

Cited by 97

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 88

Does Microglial Activation Influence Hippocampal Volume and Neuronal Function in Alzheimer’s Disease and Parkinson’s Disease Dementia?

Femminella, G. D., Ninan, S., Atkinson, R., Fan, Z., Brooks, D. J., & Edison, P. (2016) · Journal of Alzheimer’s Disease

Neuroinflammation and Neurodegeneration MechanismsDementia and Cognitive Impairment Research

Cited by 88