Chrousos, George P.

The neuroendocrinology of stress: the stress-related continuum of chronic disease development

Agorastos, A., & Chrousos, G. P. (2022) · Molecular Psychiatry

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 462

Interactions of the circadian CLOCK system and the HPA-axis

Nader, N., Chrousos, G. P., & Kino, T. (2010) · Trends in Endocrinology & Metabolism

Circadian rhythm and melatoninStress Responses and Cortisol

Cited by 449

The human glucocorticoid receptor: molecular basis of biologic function

Nicolaides, N. C., Galata, Z., Kino, T., Chrousos, G. P., & Charmandari, E. (2010) · Steroids

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 436

Cushing's syndrome in children and adolescents. Presentation, diagnosis, and therapy.

Magiakou, M. A., Mastorakos, G., Oldfield, E. H., Gomez, M. T., Doppman, J. L., Cutler, G. B., Nieman, L. K., & Chrousos, G. P. (1994) · New England Journal of Medicine

Pituitary Gland Disorders and TreatmentsAdrenal and Paraganglionic Tumors

Cited by 430

Evidence of direct estrogenic regulation of human corticotropin-releasing hormone gene expression. Potential implications for the sexual dimophism of the stress response and immune/inflammatory reaction.

Vamvakopoulos, N. C., & Chrousos, G. P. (1993) · Journal of Clinical Investigation

Estrogen and related hormone effectsStress Responses and Cortisol

Cited by 422

Sleep, the hypothalamic-pituitary-adrenal axis, and cytokines: multiple interactions and disturbances in sleep disorders

Vgontzas, A. N., & Chrousos, G. P. (2002) · Endocrinology and Metabolism Clinics of North America

Sleep and Wakefulness ResearchSleep and related disorders

Cited by 414

Developmental Trajectories of Early Life Stress and Trauma: A Narrative Review on Neurobiological Aspects Beyond Stress System Dysregulation

Agorastos, A., Pervanidou, P., Chrousos, G. P., & Baker, D. G. (2019) · Frontiers in Psychiatry

Stress Responses and CortisolChild Abuse and Trauma

Cited by 385

Major depression is associated with significant diurnal elevations in plasma interleukin-6 levels, a shift of its circadian rhythm, and loss of physiological complexity in its secretion: clinical implications

Alesci, S., Martinez, P. E., Kelkar, S., Ilias, I., Ronsaville, D. S., Listwak, S. J., Ayala, A. R., Licinio, J., Gold, H. K., Kling, M. A., et al. (2005) · The Journal of Clinical Endocrinology & Metabolism

Stress Responses and CortisolTryptophan and brain disorders

Cited by 372

Adrenocorticotropin (ACTH)- and Non-ACTH-Mediated Regulation of the Adrenal Cortex: Neural and Immune Inputs

Bornstein, S. R., & Chrousos, G. P. (1999) · The Journal of Clinical Endocrinology & Metabolism

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 354

IL-6 and its circadian secretion in humans

Vgontzas, A. N., Bixler, E. O., Lin, H.-M., Prolo, P., Trakada, G., & Chrousos, G. P. (2005) · Neuroimmunomodulation

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 338

Defective hypothalamic response to immune and inflammatory stimuli in patients with rheumatoid arthritis

Chikanza, I. C., Petrou, P., Kingsley, G., Chrousos, G., & Panayi, G. S. (1992) · Arthritis & Rheumatism

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 337

Chronic insomnia is associated with a shift of interleukin-6 and tumor necrosis factor secretion from nighttime to daytime

Vgontzas, A. N., Zoumakis, M., Papanicolaou, D. A., Bixler, E. O., Prolo, P., Lin, H.-M., Vela-Bueno, A., Kales, A., & Chrousos, G. P. (2002) · Metabolism

Sleep and related disordersSleep and Wakefulness Research

Cited by 329

Dose-Dependent Effects of Recombinant Human Interleukin-6 on Glucose Regulation

Tsigos, C., Papanicolaou, D. A., Kyrou, I., Defensor, R., Mitsiadis, C. S., & Chrousos, G. P. (1997) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesCytokine Signaling Pathways and Interactions

Cited by 324

Metabolic consequences of stress during childhood and adolescence

Pervanidou, P., & Chrousos, G. P. (2012) · Metabolism

Stress Responses and CortisolAdipokines, Inflammation, and Metabolic Diseases

Cited by 316

Puberty-related influences on brain development

Giedd, J. N., Clasen, L. S., Lenroot, R., Greenstein, D., Wallace, G. L., Ordaz, S., Molloy, E. A., Blumenthal, J. D., Tossell, J. W., Stayer, C., et al. (2006) · Molecular and Cellular Endocrinology

Sexual Differentiation and DisordersHypothalamic control of reproductive hormones

Cited by 300

Glucocorticoid action networks and complex psychiatric and/or somatic disorders

Chrousos, G. P., & Kino, T. (2007) · Stress

Stress Responses and CortisolEstrogen and related hormone effects

Cited by 292

Hypothalamic-pituitary-adrenal axis activation and stimulation of systemic vasopressin secretion by recombinant interleukin-6 in humans: potential implications for the syndrome of inappropriate vasopressin secretion.

Mastorakos, G., Weber, J. S., Magiakou, M. A., Gunn, H., & Chrousos, G. P. (1994) · The Journal of Clinical Endocrinology & Metabolism

Electrolyte and hormonal disordersStress Responses and Cortisol

Cited by 290

Impaired Endothelial Function in Young Women with Premature Ovarian Failure: Normalization with Hormone Therapy

Kalantaridou, S. N., Naka, K. K., Papanikolaou, E., Kazakos, N., Kravariti, M., Calis, K. A., Paraskevaidis, E. A., Sideris, D. A., Tsatsoulis, A., Chrousos, G. P., et al. (2004) · The Journal of Clinical Endocrinology & Metabolism

Cardiovascular Health and Disease PreventionMenopause: Health Impacts and Treatments

Cited by 284

Responses of the Hypothalamic-Pituitary-Adrenal and Renin-Angiotensin Axes and the Sympathetic System During Controlled Surgical and Anesthetic Stress

UDELSMAN, R., NORTON, J. A., JELENICH, S. E., GOLDSTEIN, D. S., LINEHAN, W. M., LORIAUX, D. L., & CHROUSOS, G. P. (1987) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 278

Hormones, emotional dispositions, and aggressive attributes in young adolescents

Susman, E. J., Inoff-Germain, G., Nottelmann, E. D., Loriaux, D. L., Cutler, G. B., & Chrousos, G. P. (1987) · Child Development

Child and Adolescent Psychosocial and Emotional DevelopmentBullying, Victimization, and Aggression

Cited by 276

Adrenomedullary dysplasia and hypofunction in patients with classic 21-hydroxylase deficiency.

Merke, D. P., Chrousos, G. P., Eisenhofer, G., Weise, M., Keil, M. F., Rogol, A. D., Van Wyk, J. J., & Bornstein, S. R. (2000) · New England Journal of Medicine

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 266

Prolonged Methylprednisolone Treatment Suppresses Systemic Inflammation in Patients with Unresolving Acute Respiratory Distress Syndrome: Evidence for Inadequate Endogenous Glucocorticoid Secretion and Inflammation-induced Immune Cell Resistance to Glucocorticoids

Meduri, G. U., Tolley, E. A., Chrousos, G. P., & Stentz, F. (2002) · American Journal of Respiratory and Critical Care Medicine

Respiratory Support and MechanismsAdrenal Hormones and Disorders

Cited by 265

The Longitudinal Course of Psychopathology in Cushing’s Syndrome after Correction of Hypercortisolism

Dorn, L. D., Burgess, E. S., Friedman, T. C., Dubbert, B., Gold, P. W., & Chrousos, G. P. (1997) · The Journal of Clinical Endocrinology & Metabolism

Pituitary Gland Disorders and TreatmentsStress Responses and Cortisol

Cited by 260

The Impact of the Nonpeptide Corticotropin-Releasing Hormone Antagonist Antalarmin on Behavioral and Endocrine Responses to Stress**This research was supported by NIMH Grant MH-50479 and the Undergraduate Research Opportunities Program at the University of Colorado at Boulder.

Deak, T., Nguyen, K. T., Ehrlich, A. L., Watkins, L. R., Spencer, R. L., Maier, S. F., Licinio, J., Wong, M.-L., Chrousos, G. P., Webster, E., et al. (1999) · Endocrinology

Stress Responses and CortisolNeuropeptides and Animal Physiology

Cited by 242