Pietiläinen, Kirsi H.

Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index

MAGIC, Speliotes, E. K., on behalf of Procardis Consortium, Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 2,912

Hundreds of variants clustered in genomic loci and biological pathways affect human height

Lango Allen, H., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., et al. (2010) · Nature

Genetic Associations and EpidemiologyGenetics and Physical Performance

Cited by 1,945

Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution

MAGIC, Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 931

Daily energy expenditure through the human life course

Pontzer, H., Yamada, Y., Sagayama, H., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., Blaak, E. E., et al. (2021) · Science

Body Composition Measurement TechniquesNutrition and Health Studies

Cited by 583

Genome-wide association study identifies multiple loci influencing human serum metabolite levels

Kettunen, J., Tukiainen, T., Sarin, A.-P., Ortega-Alonso, A., Tikkanen, E., Lyytikäinen, L.-P., Kangas, A. J., Soininen, P., Würtz, P., Silander, K., et al. (2012) · Nature Genetics

Genetic Associations and EpidemiologyMetabolomics and Mass Spectrometry Studies

Cited by 553

FGF-21 as a biomarker for muscle-manifesting mitochondrial respiratory chain deficiencies: a diagnostic study

Suomalainen, A., Elo, J. M., Pietiläinen, K. H., Hakonen, A. H., Sevastianova, K., Korpela, M., Isohanni, P., Marjavaara, S. K., Tyni, T., Kiuru-Enari, S., et al. (2011) · The Lancet Neurology

Metabolism and Genetic DisordersMitochondrial Function and Pathology

Cited by 427

Physical Inactivity and Obesity: A Vicious Circle

Pietiläinen, K. H., Kaprio, J., Borg, P., Plasqui, G., Yki‐Järvinen, H., Kujala, U. M., Rose, R. J., Westerterp, K. R., & Rissanen, A. (2008) · Obesity

Obesity, Physical Activity, DietPhysical Activity and Health

Cited by 388

Impaired Mitochondrial Biogenesis in Adipose Tissue in Acquired Obesity

Heinonen, S., Buzkova, J., Muniandy, M., Kaksonen, R., Ollikainen, M., Ismail, K., Hakkarainen, A., Lundbom, J., Lundbom, N., Vuolteenaho, K., et al. (2015) · Diabetes

Adipose Tissue and MetabolismMitochondrial Function and Pathology

Cited by 362

Genetic evidence of assortative mating in humans

Robinson, M. R., Kleinman, A., Graff, M., Vinkhuyzen, A. A. E., Couper, D., Miller, M. B., Peyrot, W. J., Abdellaoui, A., Zietsch, B. P., Nolte, I. M., et al. (2017) · Nature Human Behaviour

Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock

Cited by 326

Mitochondrial myopathy induces a starvation-like response

Tyynismaa, H., Carroll, C. J., Raimundo, N., Ahola-Erkkilä, S., Wenz, T., Ruhanen, H., Guse, K., Hemminki, A., Peltola-Mjøsund, K. E., Tulkki, V., et al. (2010) · Human Molecular Genetics

Mitochondrial Function and PathologyMetabolism and Genetic Disorders

Cited by 300

Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change

Würtz, P., Wang, Q., Kangas, A. J., Richmond, R. C., Skarp, J., Tiainen, M., Tynkkynen, T., Soininen, P., Havulinna, A. S., Kaakinen, M., et al. (2014) · PLoS Medicine

Adipokines, Inflammation, and Metabolic DiseasesMetabolomics and Mass Spectrometry Studies

Cited by 280

Once-weekly cagrilintide for weight management in people with overweight and obesity: A multicentre, randomised, double-blind, placebo-controlled and active-controlled, dose-finding phase 2 trial

Lau, D. C. W., Erichsen, L., Francisco, A. M., Satylganova, A., le Roux, C. W., McGowan, B., Pedersen, S. D., Pietiläinen, K. H., Rubino, D., & Batterham, R. L. (2021) · The Lancet

Pharmacology and Obesity TreatmentRegulation of Appetite and Obesity

Cited by 278

Notum produced by Paneth cells attenuates regeneration of aged intestinal epithelium

Pentinmikko, N., Iqbal, S., Mana, M., Andersson, S., Cognetta, A. B., Suciu, R. M., Roper, J., Luopajärvi, K., Markelin, E., Gopalakrishnan, S., et al. (2019) · Nature

Wnt/β-catenin signaling in development and cancerDigestive system and related health

Cited by 271

Coadministered Cagrilintide and Semaglutide in Adults with Overweight or Obesity.

Garvey, W. T., Blüher, M., Osorto Contreras, C. K., Davies, M. J., Winning Lehmann, E., Pietiläinen, K. H., Rubino, D., Sbraccia, P., Wadden, T., Zeuthen, N., et al. (2025) · New England Journal of Medicine

Pharmacology and Obesity TreatmentDiabetes Treatment and Management

Cited by 238

Overexpression of 11β-Hydroxysteroid Dehydrogenase-1 in Adipose Tissue Is Associated with Acquired Obesity and Features of Insulin Resistance: Studies in Young Adult Monozygotic Twins

Kannisto, K., Pietiläinen, K. H., Ehrenborg, E., Rissanen, A., Kaprio, J., Hamsten, A., & Yki-Järvinen, H. (2004) · The Journal of Clinical Endocrinology & Metabolism

Adipokines, Inflammation, and Metabolic DiseasesAdipose Tissue and Metabolism

Cited by 205

Men and women respond differently to rapid weight loss: Metabolic outcomes of a multi-centre intervention study after a low-energy diet in 2500 overweight, individuals with pre-diabetes (PREVIEW)

Christensen, P., Meinert Larsen, T., Westerterp‐Plantenga, M., Macdonald, I., Martinez, J. A., Handjiev, S., Poppitt, S., Hansen, S., Ritz, C., Astrup, A., et al. (2018) · Diabetes, Obesity and Metabolism

Diabetes, Cardiovascular Risks, and LipoproteinsBariatric Surgery and Outcomes

Cited by 188

Efficacy and safety of once-weekly semaglutide 2·4 mg versus placebo in people with obesity and prediabetes (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 trial

McGowan, B. M., Bruun, J. M., Capehorn, M., Pedersen, S. D., Pietiläinen, K. H., Muniraju, H. A. K., Quiroga, M., Varbo, A., & Lau, D. C. W. (2024) · The Lancet Diabetes & Endocrinology

Diabetes Treatment and ManagementPharmacology and Obesity Treatment

Cited by 176

Does dieting make you fat? A twin study

Pietiläinen, K. H., Saarni, S. E., Kaprio, J., & Rissanen, A. (2012) · International Journal of Obesity

Eating Disorders and BehaviorsObesity, Physical Activity, Diet

Cited by 173

New insights into the treatment of obesity

Blüher, M., Aras, M., Aronne, L. J., Batterham, R. L., Giorgino, F., Ji, L., Pietiläinen, K. H., Schnell, O., Tonchevska, E., & Wilding, J. P. H. (2023) · Diabetes, Obesity and Metabolism

Pharmacology and Obesity TreatmentBariatric Surgery and Outcomes

Cited by 158

A standard calculation methodology for human doubly labeled water studies

Speakman, J. R., Yamada, Y., Sagayama, H., Berman, E. S. F., Ainslie, P. N., Andersen, L. F., Anderson, L. J., Arab, L., Baddou, I., Bedu-Addo, K., et al. (2021) · Cell Reports Medicine

Body Composition Measurement TechniquesClinical Nutrition and Gastroenterology

Cited by 143

Liraglutide treatment improves postprandial lipid metabolism and cardiometabolic risk factors in humans with adequately controlled type 2 diabetes: a single-centre randomized controlled study

Matikainen, N., Söderlund, S., Björnson, E., Pietiläinen, K., Hakkarainen, A., Lundbom, N., Taskinen, M., & Borén, J. (2019) · Diabetes, Obesity and Metabolism

Diabetes Treatment and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 129

Leisure-time physical activity and high-risk fat: a longitudinal population-based twin study

Leskinen, T., Sipilä, S., Alen, M., Cheng, S., Pietiläinen, K. H., Usenius, J.-P., Suominen, H., Kovanen, V, Kainulainen, H., Kaprio, J., et al. (2009) · International Journal of Obesity

Physical Activity and HealthGenetics and Physical Performance

Cited by 107

Enhancing droplet-based single-nucleus RNA-seq resolution using the semi-supervised machine learning classifier DIEM

Alvarez, M., Rahmani, E., Jew, B., Garske, K. M., Miao, Z., Benhammou, J. N., Ye, C. J., Pisegna, J. R., Pietiläinen, K. H., Halperin, E., et al. (2020) · Scientific Reports

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 93

Acquired obesity and poor physical fitness impair expression of genes of mitochondrial oxidative phosphorylation in monozygotic twins discordant for obesity

Mustelin, L., Pietiläinen, K. H., Rissanen, A., Sovijärvi, A. R., Piirilä, P., Naukkarinen, J., Peltonen, L., Kaprio, J., & Yki-Järvinen, H. (2008) · American Journal of Physiology-Endocrinology and Metabolism

Adipose Tissue and MetabolismGenetics and Physical Performance

Cited by 85