Bäckhed, Fredrik

Defining a Healthy Human Gut Microbiome: Current Concepts, Future Directions, and Clinical Applications

Bäckhed, F., Fraser, C. M., Ringel, Y., Sanders, M. E., Sartor, R. B., Sherman, P. M., Versalovic, J., Young, V., & Finlay, B. B. (2012) · Cell Host & Microbe

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 836

Microbially Produced Imidazole Propionate Impairs Insulin Signaling through mTORC1

Koh, A., Molinaro, A., Ståhlman, M., Khan, M. T., Schmidt, C., Mannerås-Holm, L., Wu, H., Carreras, A., Jeong, H., Olofsson, L. E., et al. (2018) · Cell

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 824

The gut microbiota regulates bone mass in mice

Sjögren, K., Engdahl, C., Henning, P., Lerner, U. H., Tremaroli, V., Lagerquist, M. K., Bäckhed, F., & Ohlsson, C. (2012) · Journal of Bone and Mineral Research

Bone Metabolism and DiseasesGut microbiota and health

Cited by 822

Roux-en-Y Gastric Bypass and Vertical Banded Gastroplasty Induce Long-Term Changes on the Human Gut Microbiome Contributing to Fat Mass Regulation

Tremaroli, V., Karlsson, F., Werling, M., Ståhlman, M., Kovatcheva-Datchary, P., Olbers, T., Fändriks, L., le Roux, C. W., Nielsen, J., & Bäckhed, F. (2015) · Cell Metabolism

Gut microbiota and healthBariatric Surgery and Outcomes

Cited by 757

Dynamics and stabilization of the human gut microbiome during the first year of life

Bäckhed, F., Roswall, J., Peng, Y., Feng, Q., Jia, H., Kovatcheva-Datchary, P., Li, Y., Xia, Y., Xie, H., Zhong, H., et al. (2015) · Cell Host & Microbe

Gut microbiota and healthInfant Nutrition and Health

Cited by 738

Bifidobacteria or Fiber Protects against Diet-Induced Microbiota-Mediated Colonic Mucus Deterioration

Schroeder, B. O., Birchenough, G. M. H., Ståhlman, M., Arike, L., Johansson, M. E. V., Hansson, G. C., & Bäckhed, F. (2018) · Cell Host & Microbe

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 713

The composition of the gut microbiota shapes the colon mucus barrier

Jakobsson, H. E., Rodríguez‐Piñeiro, A. M., Schütte, A., Ermund, A., Boysen, P., Bemark, M., Sommer, F., Bäckhed, F., Hansson, G. C., & Johansson, M. E. (2015) · The EMBO Reports

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 700

Depicting the composition of gut microbiota in a population with varied ethnic origins but shared geography

Deschasaux, M., Bouter, K. E., Prodan, A., Levin, E., Groen, A. K., Herrema, H., Tremaroli, V., Bakker, G. J., Attaye, I., Pinto-Sietsma, S.-J., et al. (2018) · Nature Medicine

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 695

The endocannabinoid system links gut microbiota to adipogenesis

Muccioli, G. G., Naslain, D., Bäckhed, F., Reigstad, C. S., Lambert, D. M., Delzenne, N. M., & Cani, P. D. (2010) · Molecular Systems Biology

Cannabis and Cannabinoid ResearchGut microbiota and health

Cited by 691

Infection regulates pro-resolving mediators that lower antibiotic requirements

Chiang, N., Fredman, G., Bäckhed, F., Oh, S. F., Vickery, T., Schmidt, B. A., & Serhan, C. N. (2012) · Nature

Fatty Acid Research and HealthInflammatory mediators and NSAID effects

Cited by 664

Insights into the role of the microbiome in obesity and type 2 diabetes

Hartstra, A. V., Bouter, K. E. C., Bäckhed, F., & Nieuwdorp, M. (2015) · Diabetes Care

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 641

The gut microbiota modulates host energy and lipid metabolism in mice

Velagapudi, V. R., Hezaveh, R., Reigstad, C. S., Gopalacharyulu, P., Yetukuri, L., Islam, S., Felin, J., Perkins, R., Borén, J., Orešič, M., et al. (2010) · Journal of Lipid Research

Gut microbiota and healthMetabolomics and Mass Spectrometry Studies

Cited by 589

Gut microbiota regulates maturation of the adult enteric nervous system via enteric serotonin networks

De Vadder, F., Grasset, E., Mannerås Holm, L., Karsenty, G., Macpherson, A. J., Olofsson, L. E., & Bäckhed, F. (2018) · Proceedings of the National Academy of Sciences

Gastrointestinal motility and disordersGut microbiota and health

Cited by 566

Normalization of host intestinal mucus layers requires long-term microbial colonization

Johansson, M. E. V., Jakobsson, H. E., Holmén-Larsson, J., Schütte, A., Ermund, A., Rodríguez-Piñeiro, A. M., Arike, L., Wising, C., Svensson, F., Bäckhed, F., et al. (2015) · Cell Host & Microbe

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 549

The gut microbiota modulates host amino acid and glutathione metabolism in mice

Mardinoglu, A., Shoaie, S., Bergentall, M., Ghaffari, P., Zhang, C., Larsson, E., Bäckhed, F., & Nielsen, J. (2015) · Molecular Systems Biology

Gut microbiota and healthMicrobial Metabolic Engineering and Bioproduction

Cited by 383

The Gut Microbiota Modulates Energy Metabolism in the Hibernating Brown Bear Ursus arctos

Sommer, F., Ståhlman, M., Ilkayeva, O., Arnemo, J. M., Kindberg, J., Josefsson, J., Newgard, C. B., Fröbert, O., & Bäckhed, F. (2016) · Cell Reports

Gut microbiota and healthAnimal Nutrition and Physiology

Cited by 370

Lactobacillus reuteri reduces bone loss in older women with low bone mineral density: a randomized, placebo‐controlled, double‐blind, clinical trial

Nilsson, A. G., Sundh, D., Bäckhed, F., & Lorentzon, M. (2018) · Journal of Internal Medicine

Bone health and osteoporosis researchProbiotics and Fermented Foods

Cited by 323

Microbial modulation of insulin sensitivity

Khan, M. T., Nieuwdorp, M., & Bäckhed, F. (2014) · Cell Metabolism

Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases

Cited by 260

Evolution, human-microbe interactions, and life history plasticity

Rook, G., Bäckhed, F., Levin, B. R., McFall-Ngai, M. J., & McLean, A. R. (2017) · The Lancet

Gut microbiota and healthEvolution and Genetic Dynamics

Cited by 246

Microbiome-derived ethanol in nonalcoholic fatty liver disease

Meijnikman, A. S., Davids, M., Herrema, H., Aydin, O., Tremaroli, V., Rios-Morales, M., Levels, H., Bruin, S., de Brauw, M., Verheij, J., et al. (2022) · Nature Medicine

Gut microbiota and healthLiver Disease Diagnosis and Treatment

Cited by 215

The Gut Microbiota Reduces Leptin Sensitivity and the Expression of the Obesity-Suppressing Neuropeptides Proglucagon (Gcg) and Brain-Derived Neurotrophic Factor (Bdnf) in the Central Nervous System

Schéle, E., Grahnemo, L., Anesten, F., Hallén, A., Bäckhed, F., & Jansson, J.-O. (2013) · Endocrinology

Regulation of Appetite and ObesityGut microbiota and health

Cited by 209

Neonatal selection by Toll-like receptor 5 influences long-term gut microbiota composition

Fulde, M., Sommer, F., Chassaing, B., van Vorst, K., Dupont, A., Hensel, M., Basic, M., Klopfleisch, R., Rosenstiel, P., Bleich, A., et al. (2018) · Nature

Gut microbiota and healthImmune Response and Inflammation

Cited by 206

Structural requirements for TLR4-mediated LPS signalling: a biological role for LPS modifications

Bäckhed, F., Normark, S., Schweda, E. K. H., Oscarson, S., & Richter-Dahlfors, A. (2003) · Microbes and Infection

Immune Response and InflammationEscherichia coli research studies

Cited by 177

Exposure to the gut microbiota drives distinct methylome and transcriptome changes in intestinal epithelial cells during postnatal development

Pan, W.-H., Sommer, F., Falk-Paulsen, M., Ulas, T., Best, L., Fazio, A., Kachroo, P., Luzius, A., Jentzsch, M., Rehman, A., et al. (2018) · Genome Medicine

Gut microbiota and healthEpigenetics and DNA Methylation

Cited by 157