Troncoso, Juan C.

The serum- and glucocorticoid-induced kinase SGK inhibits mutant huntingtin-induced toxicity by phosphorylating serine 421 of huntingtin

Rangone, H., Poizat, G., Troncoso, J., Ross, C. A., MacDonald, M. E., Saudou, F., & Humbert, S. (2004) · European Journal of Neuroscience

Genetic Neurodegenerative DiseasesGenetics and Neurodevelopmental Disorders

Cited by 144

Neuropathology in controls and demented subjects from the Baltimore Longitudinal Study of Aging

Troncoso, J. C., Martin, L. J., Dal Forno, G., & Kawas, C. H. (1996) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 138

Neuropathologic Studies of the Baltimore Longitudinal Study of Aging (BLSA)

O'Brien, R. J., Resnick, S. M., Zonderman, A. B., Ferrucci, L., Crain, B. J., Pletnikova, O., Rudow, G., Iacono, D., Riudavets, M. A., Driscoll, I., et al. (2009) · Journal of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 137

Impact of Alzheimer's pathology on cognitive trajectories in nondemented elderly

Driscoll, I., Resnick, S. M., Troncoso, J. C., An, Y., O'Brien, R., & Zonderman, A. B. (2006) · Annals of Neurology

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 132

Rho‐associated protein kinase 1 (ROCK 1) is increased in Alzheimer's disease and ROCK 1 depletion reduces amyloid‐β levels in brain

Henderson, B. W., Gentry, E. G., Rush, T., Troncoso, J. C., Thambisetty, M., Montine, T. J., & Herskowitz, J. H. (2016) · Journal of Neurochemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 120

A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer’s disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity

DESGESCO (Dementia Genetics Spanish Consortium), E. (. D. E. D. B., van der Lee, S. J., biobank), E. (. D. E. D., IFGC (International FTD-Genomics Consortium), I. (. I. P. D. G. C., IPDGC (The International Parkinson Disease Genomics Consortium), Dementia), R.-F. (. A. M. F. I. F.-T., (NBB), N. B. B., The GIFT (Genetic Investigation in Frontotemporal Dementia and Alzheimer’s Disease) Study Group, Conway, O. J., Jansen, I., et al. (2019) · Acta Neuropathologica

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 120

Human Herpesvirus 6 Detection in Alzheimer’s Disease Cases and Controls across Multiple Cohorts

Allnutt, M. A., Johnson, K., Bennett, D. A., Connor, S. M., Troncoso, J. C., Pletnikova, O., Albert, M. S., Resnick, S. M., Scholz, S. W., De Jager, P. L., et al. (2020) · Neuron

Alzheimer's disease research and treatmentsViral-associated cancers and disorders

Cited by 119

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer’s Disease and Related Tauopathies

Castillo-Carranza, D. L., Nilson, A. N., Van Skike, C. E., Jahrling, J. B., Patel, K., Garach, P., Gerson, J. E., Sengupta, U., Abisambra, J., Nelson, P., et al. (2017) · Aging and disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 118

Personality and resilience to Alzheimer's disease neuropathology: a prospective autopsy study

Terracciano, A., Iacono, D., O’Brien, R. J., Troncoso, J. C., An, Y., Sutin, A. R., Ferrucci, L., Zonderman, A. B., & Resnick, S. M. (2013) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 113

Neuropathologic, genetic, and longitudinal cognitive profiles in primary age-related tauopathy (PART) and Alzheimer's disease

Bell, W. R., An, Y., Kageyama, Y., English, C., Rudow, G. L., Pletnikova, O., Thambisetty, M., O'Brien, R., Moghekar, A. R., Albert, M. S., et al. (2019) · Alzheimer's & Dementia

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 111

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study

Jabbari, E., Koga, S., Valentino, R. R., Reynolds, R. H., Ferrari, R., Tan, M. M. X., Rowe, J. B., Dalgard, C. L., Scholz, S. W., Dickson, D. W., et al. (2021) · The Lancet Neurology

Parkinson's Disease Mechanisms and TreatmentsAlzheimer's disease research and treatments

Cited by 111

Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study

Kramer, P. L., Xu, H., Woltjer, R. L., Westaway, S. K., Clark, D., Erten-Lyons, D., Kaye, J. A., Welsh-Bohmer, K. A., Troncoso, J. C., Markesbery, W. R., et al. (2011) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 108

Resistance to Alzheimer's pathology is associated with nuclear hypertrophy in neurons

Riudavets, M. A., Iacono, D., Resnick, S. M., O’Brien, R., Zonderman, A. B., Martin, L. J., Rudow, G., Pletnikova, O., & Troncoso, J. C. (2007) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 106

Correspondence between in vivo 11C-PiB-PET amyloid imaging and postmortem, region-matched assessment of plaques

Driscoll, I., Troncoso, J. C., Rudow, G., Sojkova, J., Pletnikova, O., Zhou, Y., Kraut, M. A., Ferrucci, L., Mathis, C. A., Klunk, W. E., et al. (2012) · Acta Neuropathologica

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 104

ABCA7 frameshift deletion associated with Alzheimer disease in African Americans

Cukier, H. N., Kunkle, B. W., Vardarajan, B. N., Rolati, S., Hamilton-Nelson, K. L., Kohli, M. A., Whitehead, P. L., Dombroski, B. A., Van Booven, D., Lang, R., et al. (2016) · Neurology Genetics

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 100

Changes in the detergent‐insoluble brain proteome linked to amyloid and tau in Alzheimer's Disease progression

Hales, C. M., Dammer, E. B., Deng, Q., Duong, D. M., Gearing, M., Troncoso, J. C., Thambisetty, M., Lah, J. J., Shulman, J. M., Levey, A. I., et al. (2016) · PROTEOMICS

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 99

Bile acid synthesis, modulation, and dementia: A metabolomic, transcriptomic, and pharmacoepidemiologic study

Varma, V. R., Wang, Y., An, Y., Varma, S., Bilgel, M., Doshi, J., Legido-Quigley, C., Delgado, J. C., Oommen, A. M., Roberts, J. A., et al. (2021) · PLOS Medicine

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 97

Sex differences in brain protein expression and disease

Wingo, A. P., Liu, Y., Gerasimov, E. S., Vattathil, S. M., Liu, J., Cutler, D. J., Epstein, M. P., Blokland, G. A. M., Thambisetty, M., Troncoso, J. C., et al. (2023) · Nature Medicine

Sex and Gender in HealthcareGenetic Associations and Epidemiology

Cited by 94

Neuropathology of preclinical and clinical lateonset Alzheimer's disease

Troncoso, J. C., Cataldo, A. M., Nixon, R. A., Barnett, J. L., Lee, M. K., Checler, F., Fowler, D. R., Smialek, J. E., Crain, B., Martin, L. J., et al. (1998) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Most cases of dementia with hippocampal sclerosis may represent frontotemporal dementia

Hatanpaa, K. J., Blass, D. M., Pletnikova, O., Crain, B. J., Bigio, E. H., Hedreen, J. C., White, C. L., & Troncoso, J. C. (2004) · Neurology

Dementia and Cognitive Impairment ResearchAmyotrophic Lateral Sclerosis Research

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Treatment with bexarotene, a compound that increases apolipoprotein-E, provides no cognitive benefit in mutant APP/PS1 mice

LaClair, K. D., Manaye, K. F., Lee, D. L., Allard, J. S., Savonenko, A. V., Troncoso, J. C., & Wong, P. C. (2013) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Ubiqutination via K27 and K29 chains signals aggregation and neuronal protection of LRRK2 by WSB1

Nucifora, F. C., Nucifora, L. G., Ng, C.-H., Arbez, N., Guo, Y., Roby, E., Shani, V., Engelender, S., Wei, D., Wang, X.-F., et al. (2016) · Nature Communications

Parkinson's Disease Mechanisms and TreatmentsUbiquitin and proteasome pathways

Cited by 82

Differential Binding of Apolipoprotein E Isoforms to Tau and Other Cytoskeletal Proteins

Fleming, L. M., Weisgraber, K. H., Strittmatter, W. J., Troncoso, J. C., & Johnson, G. V. W. (1996) · Experimental Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 82

Amyloid precursor protein increases cortical neuron size in transgenic mice

Oh, E. S., Savonenko, A. V., King, J. F., Fangmark Tucker, S. M., Rudow, G. L., Xu, G., Borchelt, D. R., & Troncoso, J. C. (2009) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 75