Fuchs, Charles S.

Fusobacterium nucleatum Potentiates Intestinal Tumorigenesis and Modulates the Tumor-Immune Microenvironment

Kostic, A. D., Chun, E., Robertson, L., Glickman, J. N., Gallini, C. A., Michaud, M., Clancy, T. E., Chung, D. C., Lochhead, P., Hold, G. L., et al. (2013) · Cell Host & Microbe

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 2,718

Safety and Efficacy of Pembrolizumab Monotherapy in Patients With Previously Treated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Clinical KEYNOTE-059 Trial

Fuchs, C. S., Doi, T., Jang, R. W., Muro, K., Satoh, T., Machado, M., Sun, W., Jalal, S. I., Shah, M. A., Metges, J.-P., et al. (2018) · JAMA Oncology

Cancer Immunotherapy and BiomarkersGastric Cancer Management and Outcomes

Cited by 1,784

Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer

Bullman, S., Pedamallu, C. S., Sicinska, E., Clancy, T. E., Zhang, X., Cai, D., Neuberg, D., Huang, K., Guevara, F., Nelson, T., et al. (2017) · Science

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 1,574

Long-term colorectal-cancer incidence and mortality after lower endoscopy

Nishihara, R., Wu, K., Lochhead, P., Morikawa, T., Liao, X., Qian, Z. R., Inamura, K., Kim, S. A., Kuchiba, A., Yamauchi, M., et al. (2013) · New England Journal of Medicine

Colorectal Cancer Screening and DetectionGlobal Cancer Incidence and Screening

Cited by 1,483

Fusobacterium nucleatum in colorectal carcinoma tissue and patient prognosis

Mima, K., Nishihara, R., Qian, Z. R., Cao, Y., Sukawa, Y., Nowak, J. A., Yang, J., Dou, R., Masugi, Y., Song, M., et al. (2016) · Gut

Gut microbiota and healthGenetic factors in colorectal cancer

Cited by 1,080

Physical activity and survival after colorectal cancer diagnosis

Meyerhardt, J. A., Giovannucci, E. L., Holmes, M. D., Chan, A. T., Chan, J. A., Colditz, G. A., & Fuchs, C. S. (2006) · Journal of Clinical Oncology

Physical Activity and HealthCancer survivorship and care

Cited by 857

Fusobacterium nucleatum and T Cells in Colorectal Carcinoma

Mima, K., Sukawa, Y., Nishihara, R., Qian, Z. R., Yamauchi, M., Inamura, K., Kim, S. A., Masuda, A., Nowak, J. A., Nosho, K., et al. (2015) · JAMA Oncology

Gut microbiota and healthCancer Immunotherapy and Biomarkers

Cited by 669

Detectable clonal mosaicism and its relationship to aging and cancer

Jacobs, K. B., Yeager, M., Zhou, W., Wacholder, S., Wang, Z., Rodriguez-Santiago, B., Hutchinson, A., Deng, X., Liu, C., Horner, M.-J., et al. (2012) · Nature Genetics

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

Cited by 589

The SIRT1 deacetylase suppresses intestinal tumorigenesis and colon cancer growth.

Firestein, R., Blander, G., Michan, S., Oberdoerffer, P., Ogino, S., Campbell, J., Bhimavarapu, A., Luikenhuis, S., de Cabo, R., Fuchs, C., et al. (2008) · PLoS ONE

Sirtuins and Resveratrol in MedicineWnt/β-catenin signaling in development and cancer

Cited by 588

Genetic Mechanisms of Immune Evasion in Colorectal Cancer

Grasso, C. S., Giannakis, M., Wells, D. K., Hamada, T., Mu, X. J., Quist, M., Nowak, J. A., Nishihara, R., Qian, Z. R., Inamura, K., et al. (2018) · Cancer Discovery

Genetic factors in colorectal cancerCancer Immunotherapy and Biomarkers

Cited by 535

Association of Obesity With Risk of Early-Onset Colorectal Cancer Among Women

Liu, P.-H., Wu, K., Ng, K., Zauber, A. G., Nguyen, L. H., Song, M., He, X., Fuchs, C. S., Ogino, S., Willett, W. C., et al. (2019) · JAMA Oncology

Cancer Risks and FactorsColorectal Cancer Screening and Detection

Cited by 514

Tumour‐infiltrating T‐cell subsets, molecular changes in colorectal cancer, and prognosis: cohort study and literature review

Nosho, K., Baba, Y., Tanaka, N., Shima, K., Hayashi, M., Meyerhardt, J. A., Giovannucci, E., Dranoff, G., Fuchs, C. S., & Ogino, S. (2010) · The Journal of Pathology

Cancer Immunotherapy and BiomarkersColorectal Cancer Treatments and Studies

Cited by 502

Real-time Genomic Characterization of Advanced Pancreatic Cancer to Enable Precision Medicine

Aguirre, A. J., Nowak, J. A., Camarda, N. D., Moffitt, R. A., Ghazani, A. A., Hazar-Rethinam, M., Raghavan, S., Kim, J., Brais, L. K., Ragon, D., et al. (2018) · Cancer Discovery

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 367

Association of Dietary Patterns With Risk of Colorectal Cancer Subtypes Classified by Fusobacterium nucleatum in Tumor Tissue

Mehta, R. S., Nishihara, R., Cao, Y., Song, M., Mima, K., Qian, Z. R., Nowak, J. A., Kosumi, K., Hamada, T., Masugi, Y., et al. (2017) · JAMA Oncology

Nutritional Studies and DietGut microbiota and health

Cited by 325

Use of Adjuvant Chemotherapy and Radiation Therapy for Colorectal Cancer in a Population-Based Cohort

Ayanian, J. Z., Zaslavsky, A. M., Fuchs, C. S., Guadagnoli, E., Creech, C. M., Cress, R. D., O’Connor, L. C., West, D. W., Allen, M. E., Wolf, R. E., et al. (2003) · Journal of Clinical Oncology

Colorectal Cancer Surgical TreatmentsColorectal Cancer Treatments and Studies

Cited by 308

Oral mTOR inhibitor everolimus in patients with gemcitabine-refractory metastatic pancreatic cancer

Wolpin, B. M., Hezel, A. F., Abrams, T., Blaszkowsky, L. S., Meyerhardt, J. A., Chan, J. A., Enzinger, P. C., Allen, B., Clark, J. W., Ryan, D. P., et al. (2009) · Journal of Clinical Oncology

Pancreatic and Hepatic Oncology ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 297

Fusobacterium nucleatum in colorectal carcinoma tissue according to tumor location

Mima, K., Cao, Y., Chan, A. T., Qian, Z. R., Nowak, J. A., Masugi, Y., Shi, Y., Song, M., da Silva, A., Gu, M., et al. (2016) · Clinical and Translational Gastroenterology

Gut microbiota and healthOral microbiology and periodontitis research

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Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer

Klein, A. P., Wolpin, B. M., Risch, H. A., Stolzenberg-Solomon, R. Z., Mocci, E., Zhang, M., Canzian, F., Childs, E. J., Hoskins, J. W., Jermusyk, A., et al. (2018) · Nature Communications

Pancreatic and Hepatic Oncology ResearchGenetic Associations and Epidemiology

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Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma

Qian, Z. R., Rubinson, D. A., Nowak, J. A., Morales-Oyarvide, V., Dunne, R. F., Kozak, M. M., Welch, M. W., Brais, L. K., Da Silva, A., Li, T., et al. (2018) · JAMA Oncology

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

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Prognostic Role of PIK3CA Mutation in Colorectal Cancer: Cohort Study and Literature Review

Liao, X., Morikawa, T., Lochhead, P., Imamura, Y., Kuchiba, A., Yamauchi, M., Nosho, K., Qian, Z. R., Nishihara, R., Meyerhardt, J. A., et al. (2012) · Clinical Cancer Research

Colorectal Cancer Treatments and StudiesGenetic factors in colorectal cancer

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Insulin, the insulin-like growth factor axis, and mortality in patients with nonmetastatic colorectal cancer.

Wolpin, B. M., Meyerhardt, J. A., Chan, A. T., Ng, K., Chan, J. A., Wu, K., Pollak, M. N., Giovannucci, E. L., & Fuchs, C. S. (2009) · Journal of Clinical Oncology

Growth Hormone and Insulin-like Growth FactorsCancer Risks and Factors

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Germline cancer susceptibility gene variants, somatic second hits, and survival outcomes in patients with resected pancreatic cancer

Yurgelun, M. B., Chittenden, A. B., Morales-Oyarvide, V., Rubinson, D. A., Dunne, R. F., Kozak, M. M., Qian, Z. R., Welch, M. W., Brais, L. K., Da Silva, A., et al. (2019) · Genetics in Medicine

Pancreatic and Hepatic Oncology ResearchBRCA gene mutations in cancer

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Etiologic field effect: reappraisal of the field effect concept in cancer predisposition and progression

Lochhead, P., Chan, A. T., Nishihara, R., Fuchs, C. S., Beck, A. H., Giovannucci, E., & Ogino, S. (2015) · Modern Pathology

Cancer Genomics and DiagnosticsHealth, Environment, Cognitive Aging

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Fiber Intake and Survival After Colorectal Cancer Diagnosis

Song, M., Wu, K., Meyerhardt, J. A., Ogino, S., Wang, M., Fuchs, C. S., Giovannucci, E. L., & Chan, A. T. (2018) · JAMA Oncology

Nutritional Studies and DietFood composition and properties

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