Greengard, Paul

Phosphorylation and inactivation of protein phosphatase 1 by cyclin-dependent kinases.

Dohadwala, M., da Cruz e Silva, E. F., Hall, F. L., Williams, R. T., Carbonaro-Hall, D. A., Nairn, A. C., Greengard, P., & Berndt, N. (1994) · Proceedings of the National Academy of Sciences

Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling

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Impaired recycling of synaptic vesicles after acute perturbation of the presynaptic actin cytoskeleton

Shupliakov, O., Bloom, O., Gustafsson, J. S., Kjaerulff, O., Löw, P., Tomilin, N., Pieribone, V. A., Greengard, P., & Brodin, L. (2002) · Proceedings of the National Academy of Sciences

Cellular transport and secretionNeuroscience and Neuropharmacology Research

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Cocaine Increases Dopamine Release by Mobilization of a Synapsin-Dependent Reserve Pool

Venton, B. J., Seipel, A. T., Phillips, P. E. M., Wetsel, W. C., Gitler, D., Greengard, P., Augustine, G. J., & Wightman, R. M. (2006) · The Journal of Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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The Alzheimer Amyloid Precursor Protein (APP) and Fe65, an APP-Binding Protein, Regulate Cell Movement

Sabo, S. L., Ikin, A. F., Buxbaum, J. D., & Greengard, P. (2001) · The Journal of Cell Biology

Alzheimer's disease research and treatmentsCellular Mechanics and Interactions

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Cellular and molecular basis for stress-induced depression

Seo, J.-S., Wei, J., Qin, L., Kim, Y., Yan, Z., & Greengard, P. (2017) · Molecular Psychiatry

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

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Cell type–specific regulation of DARPP-32 phosphorylation by psychostimulant and antipsychotic drugs

Bateup, H. S., Svenningsson, P., Kuroiwa, M., Gong, S., Nishi, A., Heintz, N., & Greengard, P. (2008) · Nature Neuroscience

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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Adaptor complex AP2/PICALM, through interaction with LC3, targets Alzheimer's APP-CTF for terminal degradation via autophagy

Tian, Y., Chang, J. C., Fan, E. Y., Flajolet, M., & Greengard, P. (2013) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyAlzheimer's disease research and treatments

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Three-Dimensional Study of Alzheimer’s Disease Hallmarks Using the iDISCO Clearing Method

Liebmann, T., Renier, N., Bettayeb, K., Greengard, P., Tessier-Lavigne, M., & Flajolet, M. (2016) · Cell Reports

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

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The Amyloid Precursor Protein and Its Regulatory Protein, FE65, in Growth Cones and Synapses In Vitro and In Vivo

Sabo, S. L., Ikin, A. F., Buxbaum, J. D., & Greengard, P. (2003) · The Journal of Neuroscience

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

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Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington’s disease

Plotkin, J. L., Day, M., Peterson, J. D., Xie, Z., Kress, G. J., Rafalovich, I., Kondapalli, J., Gertler, T. S., Flajolet, M., Greengard, P., et al. (2014) · Neuron

Genetic Neurodegenerative DiseasesNerve injury and regeneration

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Loss of SATB1 Induces p21-Dependent Cellular Senescence in Post-mitotic Dopaminergic Neurons

Riessland, M., Kolisnyk, B., Kim, T. W., Cheng, J., Ni, J., Pearson, J. A., Park, E. J., Dam, K., Acehan, D., Ramos-Espiritu, L. S., et al. (2019) · Cell Stem Cell

Telomeres, Telomerase, and SenescenceParkinson's Disease Mechanisms and Treatments

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Selective Neuronal Vulnerability in Alzheimer’s Disease: A Network-Based Analysis

Roussarie, J.-P., Yao, V., Rodriguez-Rodriguez, P., Oughtred, R., Rust, J., Plautz, Z., Kasturia, S., Albornoz, C., Wang, W., Schmidt, E. F., et al. (2020) · Neuron

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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Cholinergic interneurons in the nucleus accumbens regulate depression-like behavior

Warner-Schmidt, J. L., Schmidt, E. F., Marshall, J. J., Rubin, A. J., Arango-Lievano, M., Kaplitt, M. G., Ibañez-Tallon, I., Heintz, N., & Greengard, P. (2012) · Proceedings of the National Academy of Sciences

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

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The Rho-Specific GEF Lfc Interacts with Neurabin and Spinophilin to Regulate Dendritic Spine Morphology

Ryan, X. P., Alldritt, J., Svenningsson, P., Allen, P. B., Wu, G.-Y., Nairn, A. C., & Greengard, P. (2005) · Neuron

Neuroscience and Neuropharmacology ResearchProtein Kinase Regulation and GTPase Signaling

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Reversal of Depressed Behaviors in Mice by p11 Gene Therapy in the Nucleus Accumbens

Alexander, B., Warner-Schmidt, J., Eriksson, T. M., Tamminga, C., Arango-Lievano, M., Ghose, S., Vernov, M., Stavarache, M., Musatov, S., Flajolet, M., et al. (2010) · Science Translational Medicine

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

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Roscovitine-Derived, Dual-Specificity Inhibitors of Cyclin-Dependent Kinases and Casein Kinases 1

Oumata, N., Bettayeb, K., Ferandin, Y., Demange, L., Lopez-Giral, A., Goddard, M.-L., Myrianthopoulos, V., Mikros, E., Flajolet, M., Greengard, P., et al. (2008) · Journal of Medicinal Chemistry

Alzheimer's disease research and treatmentsHeterocyclic Compound Synthesis and Bioactivity

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The Neurobiology of Dopamine Signaling

Greengard, P. (2001) · Bioscience Reports

Neurotransmitter Receptor Influence on BehaviorNeuroscience and Neuropharmacology Research

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Distinct Roles of Synapsin I and Synapsin II during Neuronal Development

Ferreira, A., Chin, L.-S., Li, L., Lanier, L. M., Kosik, K. S., & Greengard, P. (1998) · Molecular Medicine

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

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Identification of neurodegenerative factors using translatome–regulatory network analysis

Brichta, L., Shin, W., Jackson-Lewis, V., Blesa, J., Yap, E.-L., Walker, Z., Zhang, J., Roussarie, J.-P., Alvarez, M. J., Califano, A., et al. (2015) · Nature Neuroscience

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

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WAVE1 controls neuronal activity-induced mitochondrial distribution in dendritic spines

Sung, J. Y., Engmann, O., Teylan, M. A., Nairn, A. C., Greengard, P., & Kim, Y. (2008) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMitochondrial Function and Pathology

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Role of the Astroglial Glutamate Exchanger xCT in Ventral Hippocampus in Resilience to Stress

Nasca, C., Bigio, B., Zelli, D., de Angelis, P., Lau, T., Okamoto, M., Soya, H., Ni, J., Brichta, L., Greengard, P., et al. (2017) · Neuron

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

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HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors

Cheng, J., Umschweif, G., Leung, J., Sagi, Y., & Greengard, P. (2019) · Neuron

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

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Amyloid‐β oligomers are inefficiently measured by enzyme‐linked immunosorbent assay

Stenh, C., Englund, H., Lord, A., Johansson, A., Almeida, C. G., Gellerfors, P., Greengard, P., Gouras, G. K., Lannfelt, L., & Nilsson, L. N. G. (2005) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

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The role of ventral striatal cAMP signaling in stress-induced behaviors

Plattner, F., Hayashi, K., Hernández, A., Benavides, D. R., Tassin, T. C., Tan, C., Day, J., Fina, M. W., Yuen, E. Y., Yan, Z., et al. (2015) · Nature Neuroscience

Phosphodiesterase function and regulationNeurotransmitter Receptor Influence on Behavior

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