HCN2 Channels in Cholinergic Interneurons of Nucleus Accumbens Shell Regulate Depressive Behaviors

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HCN channels in the lateral habenula regulate pain and comorbid depressive-like behaviors in mice

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An accumbal microcircuit for the transition from acute to chronic pain

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Mutants of the Zebrafish K+ Channel Hcn2b Exhibit Epileptic-like Behaviors

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Electroacupuncture alleviates depression-like behaviours via a neural mechanism involving activation of Nucleus Accumbens Shell

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A thalamic circuit facilitates stress susceptibility via melanocortin 4 receptor‐mediated activation of nucleus accumbens shell

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Heightened reward response is associated with HCN2 overexpression in the ventral tegmental area in morphine-sensitized rats

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Chronic Striatal Cholinergic Interneuron Excitation Causes Cerebral Palsy‐Related Dystonic Behavior in Mice

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Striatal CDK5 Regulates Cholinergic Neuron Activation and Dyskinesia-like Behaviors through BK Channels

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Characterizing microglial heterogeneity in autophagy impairment of Paraquat-induced Parkinson’s disease-like neurodegeneration

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Ahnak in the prefrontal cortex mediates behavioral correlates of stress resilience and rapid antidepressant action in mice

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Shank3 contributes to neuropathic pain by facilitating the SNI-dependent increase of HCN2 and the expression of PSD95

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A Neurostimulation-Triggered Trigeminal Neuralgia-like Pain

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The Involvement of the Ventral Tegmental Area in the Electroacupuncture Alleviation of Anxiety-Like Behaviors Induced by Chronic Restraint Stress in Mice

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Projections from ventral hippocampus to nucleus accumbens’ cholinergic neurons are altered in depression

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Stress-induced alterations of mesocortical and mesolimbic dopaminergic pathwaysPreprint

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Glutamatergic projections from ventral hippocampus to nucleus accumbens cholinergic neurons are altered in a mouse model of depressionPreprint

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Chronic striatal cholinergic interneuron excitation induces clinically-relevant dystonic behavior in micePreprint

Gemperli, K., Lu, X., Chintalapati, K., Rust, A., Bajpai, R., Suh, N., Blackburn, J., Gelineau‐Morel, R., Kruer, M. C., Mingbundersuk, D., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.07.19.549778 · Cited by 3 · see citing works

Stress-induced Alterations of Mesocortical and Mesolimbic Dopaminergic PathwaysPreprint

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Chemogenetic activation of hippocampal area CA2 promotes acute and chronic seizures in a mouse model of epilepsy

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Effects of nicotine on catecholaminergic neurotransmission in a premotor stage model of Parkinson’s disease

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Depression increases the risk of tuberculosis: Preliminary observations

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Loss of muscarinic M5 receptor function manifests disparate impairments in exploratory behavior in male and female mice despite common dopamine regulationPreprint

Razidlo, J. A., Fausner, S. M. L., Wang, L. C., Mirza, S. A., Alvarez, V. A., & Lemos, J. C. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.11.451965 · Cited by 1 · see citing works

HCN2 in cholinergic interneurons of the nucleus accumbens mediates reward responsePreprint

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Cholinergic interneurons in the nucleus accumbens are a site of cellular convergence for corticotropin release factor and estrogen regulationPreprint

Olson, K. L., Ingebretson, A. E., Vogiatzoglou, E., Mermelstein, P. G., & Lemos, J. C. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.04.13.589360 · Cited by 1 · see citing works

Synaptic Plasticity—Intrinsic Excitability and Antidepressant Discovery

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Targeting pacemaker channels in depression

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Deciphering cell-type specific signal transduction in the brain: Challenges and promises

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Paul Greengard: A persistent desire to comprehend the brain, and also to fix it

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Cholinergic Neurons of the Nucleus Accumbens Enhance Cocaine-Induced Dopaminergic Signaling and RewardPreprint

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HCN2 channels in the ventral tegmental area regulate behavioral responses to chronic stress

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A Possible Link Between HCN Channels and Depression

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