Wysocki, Vicki H.

How many human proteoforms are there?

Aebersold, R., Agar, J. N., Amster, I. J., Baker, M. S., Bertozzi, C. R., Boja, E. S., Costello, C. E., Cravatt, B. F., Fenselau, C., Garcia, B. A., et al. (2018) · Nature Chemical Biology

Advanced Proteomics Techniques and ApplicationsMass Spectrometry Techniques and Applications

Cited by 907

Rapid online buffer exchange for screening of proteins, protein complexes and cell lysates by native mass spectrometry

VanAernum, Z. L., Busch, F., Jones, B. J., Jia, M., Chen, Z., Boyken, S. E., Sahasrabuddhe, A., Baker, D., & Wysocki, V. H. (2020) · Nature Protocols

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 169

Chemical and pathogen-induced inflammation disrupt the murine intestinal microbiome

Borton, M. A., Sabag-Daigle, A., Wu, J., Solden, L. M., O’Banion, B. S., Daly, R. A., Wolfe, R. A., Gonzalez, J. F., Wysocki, V. H., Ahmer, B. M. M., et al. (2017) · Microbiome

Gut microbiota and healthInflammatory Bowel Disease

Cited by 149

Biogenic manganese oxide nanoparticle formation by a multimeric multicopper oxidase Mnx

Romano, C. A., Zhou, M., Song, Y., Wysocki, V. H., Dohnalkova, A. C., Kovarik, L., Paša-Tolić, L., & Tebo, B. M. (2017) · Nature Communications

Metal-Catalyzed Oxygenation MechanismsEnzyme Structure and Function

Cited by 102

Impact of charge state on gas-phase behaviors of noncovalent protein complexes in collision induced dissociation and surface induced dissociation

Zhou, M., Dagan, S., & Wysocki, V. H. (2013) · The Analyst

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 92

Revealing the Quaternary Structure of a Heterogeneous Noncovalent Protein Complex through Surface-Induced Dissociation

Blackwell, A. E., Dodds, E. D., Bandarian, V., & Wysocki, V. H. (2011) · Analytical Chemistry

Mass Spectrometry Techniques and ApplicationsAdvanced Proteomics Techniques and Applications

Cited by 84

The exon junction complex undergoes a compositional switch that alters mRNP structure and nonsense-mediated mRNA decay activity

Mabin, J. W., Woodward, L. A., Patton, R., Yi, Z., Jia, M., Wysocki, V., Bundschuh, R., & Singh, G. (2018) · Cell Reports

RNA Research and SplicingRNA and protein synthesis mechanisms

Cited by 84

A Dimer Interface Mutation in Glyceraldehyde-3-Phosphate Dehydrogenase Regulates Its Binding to AU-rich RNA

White, M. R., Khan, M. M., Deredge, D., Ross, C. R., Quintyn, R., Zucconi, B. E., Wysocki, V. H., Wintrode, P. L., Wilson, G. M., & Garcin, E. D. (2015) · Journal of Biological Chemistry

RNA Research and SplicingProtein Structure and Dynamics

Cited by 66

Comparative Structural Analysis of 20S Proteasome Ortholog Protein Complexes by Native Mass Spectrometry

Vimer, S., Ben-Nissan, G., Morgenstern, D., Kumar-Deshmukh, F., Polkinghorn, C., Quintyn, R. S., Vasil’ev, Y. V., Beckman, J. S., Elad, N., Wysocki, V. H., et al. (2020) · ACS Central Science

Mass Spectrometry Techniques and ApplicationsUbiquitin and proteasome pathways

Cited by 63

Interactions between CusF and CusB identified by NMR spectroscopy and chemical cross-linking coupled to mass spectrometry

Mealman, T. D., Bagai, I., Singh, P., Goodlett, D. R., Rensing, C., Zhou, H., Wysocki, V. H., & McEvoy, M. M. (2011) · Biochemistry

Bacterial Genetics and BiotechnologyDrug Transport and Resistance Mechanisms

Cited by 53

Protein shape sampled by ion mobility mass spectrometry consistently improves protein structure prediction

Turzo, S. B. A., Seffernick, J. T., Rolland, A. D., Donor, M. T., Heinze, S., Prell, J. S., Wysocki, V. H., & Lindert, S. (2022) · Nature Communications

Protein Structure and DynamicsMass Spectrometry Techniques and Applications

Cited by 47

Protein quaternary structures in solution are a mixture of multiple forms

Marciano, S., Dey, D., Listov, D., Fleishman, S. J., Sonn-Segev, A., Mertens, H., Busch, F., Kim, Y., Harvey, S. R., Wysocki, V. H., et al. (2022) · Chemical Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 41

Molecular basis of Gabija anti-phage supramolecular assemblies

Yang, X.-Y., Shen, Z., Xie, J., Greenwald, J., Marathe, I., Lin, Q., Xie, W. J., Wysocki, V. H., & Fu, T.-M. (2024) · Nature Structural & Molecular Biology

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 23

STK11/LKB1 Loss of Function Is Associated with Global DNA Hypomethylation and S -Adenosyl-Methionine Depletion in Human Lung Adenocarcinoma

Koenig, M. J., Agana, B. A., Kaufman, J. M., Sharpnack, M. F., Wang, W. Z., Weigel, C., Navarro, F. C. P., Amann, J. M., Cacciato, N., Arasada, R. R., et al. (2021) · Cancer Research

Epigenetics and DNA MethylationLung Cancer Treatments and Mutations

Cited by 18

Topological rearrangements activate the HerA-DUF anti-phage defense system

Rish, A. D., Fosuah, E., Shen, Z., Marathe, I. A., Wysocki, V. H., & Fu, T.-M. (2024) · Molecular Cell

Bacteriophages and microbial interactionsCRISPR and Genetic Engineering

Cited by 8

Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM

Li, W., Yang, H., Stachowski, K., Norris, A. S., Lichtenthal, K., Kelly, S., Gollnick, P., Wysocki, V. H., & Foster, M. P. (2024) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsBacterial Genetics and Biotechnology

Cited by 4

Structural basis of nearest-neighbor cooperativity in the ring-shaped gene regulatory protein TRAP from protein engineering and cryo-EM

Li, W., Yang, H., Stachowski, K., Norris, A. S., Lichtenthal, K., Kelly, S., Gollnick, P., Wysocki, V. H., & Foster, M. P. (2025) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsBacterial Genetics and Biotechnology

Cited by 4

Protein Quaternary Structures in Solution are a Mixture of Multiple forms

Marciano, S., Dey, D., Listov, D., Fleishman, S. J., Sonn-Segev, A., Mertens, H., Busch, F., Kim, Y., Harvey, S. R., Wysocki, V. H., et al. (2022) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 3