Ozanne, Susan E.

Diet-Induced Obesity in Female Mice Leads to Offspring Hyperphagia, Adiposity, Hypertension, and Insulin Resistance: A Novel Murine Model of Developmental Programming

Samuelsson, A.-M., Matthews, P. A., Argenton, M., Christie, M. R., McConnell, J. M., Jansen, E. H. J. M., Piersma, A. H., Ozanne, S. E., Twinn, D. F., Remacle, C., et al. (2008) · Hypertension

Birth, Development, and HealthDiet, Metabolism, and Disease

Cited by 923

Epigenetics and DOHaD: From Basics to Birth and Beyond

Bianco-Miotto, T., Craig, J. M., Gasser, Y. P., van Dijk, S. J., & Ozanne, S. E. (2017) · Journal of Developmental Origins of Health and Disease

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 361

Maternal diet and aging alter the epigenetic control of a promoter–enhancer interaction at the Hnf4a gene in rat pancreatic islets

Sandovici, I., Smith, N. H., Nitert, M. D., Ackers-Johnson, M., Uribe-Lewis, S., Ito, Y., Jones, R. H., Marquez, V. E., Cairns, W., Tadayyon, M., et al. (2011) · Proceedings of the National Academy of Sciences

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 326

Mechanisms involved in the developmental programming of adulthood disease

Warner, M. J., & Ozanne, S. E. (2010) · Biochemical Journal

Birth, Development, and HealthPrenatal Substance Exposure Effects

Cited by 316

Maternal obesity during pregnancy and lactation programs the development of offspring non-alcoholic fatty liver disease in mice

Oben, J. A., Mouralidarane, A., Samuelsson, A.-M., Matthews, P. J., Morgan, M. L., Mckee, C., Soeda, J., Fernandez-Twinn, D. S., Martin-Gronert, M. S., Ozanne, S. E., et al. (2010) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentBirth, Development, and Health

Cited by 314

Diabetes in old male offspring of rat dams fed a reduced protein diet

Petry, C. J., Dorling, M. W., Pawlak, D. B., Ozanne, S. E., & Hales, C. N. (2001) · Journal of Diabetes Research

Birth, Development, and HealthPancreatic function and diabetes

Cited by 254

Neonatal, infant, and childhood growth following metformin versus insulin treatment for gestational diabetes: a systematic review and meta-analysis

Tarry-Adkins, J. L., Aiken, C. E., & Ozanne, S. E. (2019) · PLoS Medicine

Gestational Diabetes Research and ManagementBirth, Development, and Health

Cited by 251

Mechanisms of disease: the developmental origins of disease and the role of the epigenotype

Ozanne, S. E., & Constância, M. (2007) · Nature Clinical Practice Endocrinology & Metabolism

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 232

Gene-Environment Interactions Controlling Energy and Glucose Homeostasis and the Developmental Origins of Obesity

Bouret, S., Levin, B. E., & Ozanne, S. E. (2015) · Physiological Reviews

Birth, Development, and HealthRegulation of Appetite and Obesity

Cited by 157

Programming of adipose tissue miR-483-3p and GDF-3 expression by maternal diet in type 2 diabetes

Ferland-McCollough, D., Fernandez-Twinn, D. S., Cannell, I. G., David, H., Warner, M., Vaag, A. A., Bork-Jensen, J., Brøns, C., Gant, T. W., Willis, A. E., et al. (2012) · Cell Death & Differentiation

Birth, Development, and HealthMicroRNA in disease regulation

Cited by 149

The Early Origins of Obesity and Insulin Resistance: Timing, Programming and Mechanisms

Nicholas, L. M., Morrison, J. L., Rattanatray, L., Zhang, S., Ozanne, S. E., & McMillen, I. C. (2016) · International Journal of Obesity

Birth, Development, and HealthGestational Diabetes Research and Management

Cited by 146

The programming of cardiac hypertrophy in the offspring by maternal obesity is associated with hyperinsulinemia, AKT, ERK, and mTOR activation

Fernandez-Twinn, D. S., Blackmore, H. L., Siggens, L., Giussani, D. A., Cross, C. M., Foo, R., & Ozanne, S. E. (2012) · Endocrinology

Birth, Development, and HealthCardiac Fibrosis and Remodeling

Cited by 141

Oxidative Stress and Altered Lipid Homeostasis in the Programming of Offspring Fatty Liver by Maternal Obesity

Alfaradhi, M. Z., Fernandez-Twinn, D. S., Martin-Gronert, M. S., Musial, B., Fowden, A., & Ozanne, S. E. (2014) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology

Birth, Development, and HealthLiver Disease Diagnosis and Treatment

Cited by 136

Maternal diet-induced obesity programs cardiovascular dysfunction in adult male mouse offspring independent of current body weight

Blackmore, H. L., Niu, Y., Fernandez-Twinn, D. S., Tarry-Adkins, J. L., Giussani, D. A., & Ozanne, S. E. (2014) · Endocrinology

Birth, Development, and HealthCardiovascular Function and Risk Factors

Cited by 127

Exercise rescues obese mothers’ insulin sensitivity, placental hypoxia and male offspring insulin sensitivity

Fernandez-Twinn, D. S., Gascoin, G., Musial, B., Carr, S., Duque-Guimaraes, D., Blackmore, H. L., Alfaradhi, M. Z., Loche, E., Sferruzzi-Perri, A. N., Fowden, A. L., et al. (2017) · Scientific Reports

Birth, Development, and HealthGestational Diabetes Research and Management

Cited by 115

Downregulation of IRS-1 in adipose tissue of offspring of obese mice is programmed cell-autonomously through post-transcriptional mechanisms

Fernandez-Twinn, D. S., Alfaradhi, M. Z., Martin-Gronert, M. S., Duque-Guimaraes, D. E., Piekarz, A., Ferland-McCollough, D., Bushell, M., & Ozanne, S. E. (2014) · Molecular Metabolism

Birth, Development, and HealthAdipokines, Inflammation, and Metabolic Diseases

Cited by 114

Catch-up growth following intra-uterine growth-restriction programmes an insulin-resistant phenotype in adipose tissue

Berends, L. M., Fernandez-Twinn, D. S., Martin-Gronert, M. S., Cripps, R. L., & Ozanne, S. E. (2013) · International Journal of Obesity

Birth, Development, and HealthAdipokines, Inflammation, and Metabolic Diseases

Cited by 109

Early-life nutrition modulates the epigenetic state of specific rDNA genetic variants in mice

Holland, M. L., Lowe, R., Caton, P. W., Gemma, C., Carbajosa, G., Danson, A. F., Carpenter, A. A. M., Loche, E., Ozanne, S. E., & Rakyan, V. K. (2016) · Science

Birth, Development, and HealthEpigenetics and DNA Methylation

Cited by 106

Maternal diet-induced obesity programmes cardiac dysfunction in male mice independently of post-weaning diet

Loche, E., Blackmore, H. L., Carpenter, A. A., Beeson, J. H., Pinnock, A., Ashmore, T. J., Aiken, C. E., de Almeida-Faria, J., Schoonejans, J. M., Giussani, D. A., et al. (2018) · Cardiovascular Research

Birth, Development, and HealthCardiovascular Function and Risk Factors

Cited by 105

Maternal exercise intervention in obese pregnancy improves the cardiovascular health of the adult male offspring

Beeson, J. H., Blackmore, H. L., Carr, S. K., Dearden, L., Duque-Guimarães, D. E., Kusinski, L. C., Pantaleão, L. C., Pinnock, A. G., Aiken, C. E., Giussani, D. A., et al. (2018) · Molecular Metabolism

Birth, Development, and HealthGestational Diabetes Research and Management

Cited by 73

Comparative impact of pharmacological treatments for gestational diabetes on neonatal anthropometry independent of maternal glycaemic control: a systematic review and meta-analysis

Tarry-Adkins, J. L., Aiken, C. E., & Ozanne, S. E. (2020) · PLoS Medicine

Gestational Diabetes Research and ManagementPregnancy and Medication Impact

Cited by 73

Divergence of mechanistic pathways mediating cardiovascular aging and developmental programming of cardiovascular disease

Allison, B. J., Kaandorp, J. J., Kane, A. D., Camm, E. J., Lusby, C., Cross, C. M., Nevin‐Dolan, R., Thakor, A. S., Derks, J. B., Tarry‐Adkins, J. L., et al. (2016) · The FASEB Journal

Nitric Oxide and Endothelin EffectsBirth, Development, and Health

Cited by 73

Effective interventions in preventing gestational diabetes mellitus: A systematic review and meta-analysis

Takele, W. W., Vesco, K. K., Josefson, J., Redman, L. M., Hannah, W., Bonham, M. P., Chen, M., Chivers, S. C., Fawcett, A. J., Grieger, J. A., et al. (2024) · Communications Medicine

Gestational Diabetes Research and ManagementDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 55

Coenzyme Q10 Prevents Accelerated Cardiac Aging in a Rat Model of Poor Maternal Nutrition and Accelerated Postnatal Growth

Tarry-Adkins, J. L., Blackmore, H. L., Martin-Gronert, M. S., Fernandez-Twinn, D. S., McConnell, J. M., Hargreaves, I. P., Giussani, D. A., & Ozanne, S. E. (2013) · Molecular Metabolism

Birth, Development, and HealthCoenzyme Q10 studies and effects

Cited by 47