Tuszynski, Mark H.

A phase 1 clinical trial of nerve growth factor gene therapy for Alzheimer disease

Tuszynski, M. H., Thal, L., Pay, M., Salmon, D. P., U, H. S., Bakay, R., Patel, P., Blesch, A., Vahlsing, H. L., Ho, G., et al. (2005) · Nature Medicine

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 1,050

Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease

Nagahara, A. H., Merrill, D. A., Coppola, G., Tsukada, S., Schroeder, B. E., Shaked, G. M., Wang, L., Blesch, A., Kim, A., Conner, J. M., et al. (2009) · Nature Medicine

Alzheimer's disease research and treatmentsNerve injury and regeneration

Cited by 1,034

Potential therapeutic uses of BDNF in neurological and psychiatric disorders

Nagahara, A. H., & Tuszynski, M. H. (2011) · Nature Reviews Drug Discovery

Nerve injury and regenerationAlzheimer's disease research and treatments

Cited by 867

Regulation of axonal regeneration after mammalian spinal cord injury

Zheng, B., & Tuszynski, M. H. (2023) · Nature Reviews Molecular Cell Biology

Nerve injury and regenerationSpinal Cord Injury Research

Cited by 328

Nerve Growth Factor Gene Therapy: Activation of Neuronal Responses in Alzheimer Disease

Tuszynski, M. H., Yang, J. H., Barba, D., U, H.-S., Bakay, R. A. E., Pay, M. M., Masliah, E., Conner, J. M., Kobalka, P., Roy, S., et al. (2015) · JAMA Neurology

Alzheimer's disease research and treatmentsVirus-based gene therapy research

Cited by 287

Injured adult neurons regress to an embryonic transcriptional growth state

Poplawski, G. H. D., Kawaguchi, R., Van Niekerk, E., Lu, P., Mehta, N., Canete, P., Lie, R., Dragatsis, I., Meves, J. M., Zheng, B., et al. (2020) · Nature

Nerve injury and regenerationSpinal Cord Injury Research

Cited by 247

Adeno-Associated Viral Vector (Serotype 2)–Nerve Growth Factor for Patients With Alzheimer Disease: A Randomized Clinical Trial

Rafii, M. S., Tuszynski, M. H., Thomas, R. G., Barba, D., Brewer, J. B., Rissman, R. A., Siffert, J., Aisen, P. S., & for the AAV2-NGF Study Team (2018) · JAMA Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 219

NGF Is Essential for Hippocampal Plasticity and Learning

Conner, J. M., Franks, K. M., Titterness, A. K., Russell, K., Merrill, D. A., Christie, B. R., Sejnowski, T. J., & Tuszynski, M. H. (2009) · The Journal of Neuroscience

Nerve injury and regenerationMemory and Neural Mechanisms

Cited by 189

Conservation of neuronal number and size in the entorhinal cortex of behaviorally characterized aged rats

Merrill, D. A., Chiba, A. A., & Tuszynski, M. H. (2001) · Journal of Comparative Neurology

Memory and Neural MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 118

Age-related cognitive deficits in rhesus monkeys mirror human deficits on an automated test battery

Nagahara, A. H., Bernot, T., & Tuszynski, M. H. (2010) · Neurobiology of Aging

Dementia and Cognitive Impairment ResearchCognitive Abilities and Testing

Cited by 110

Structural plasticity within highly specific neuronal populations identifies a unique parcellation of motor learning in the adult brain

Wang, L., Conner, J. M., Rickert, J., & Tuszynski, M. H. (2011) · Proceedings of the National Academy of Sciences

Motor Control and AdaptationNeuroscience and Neuropharmacology Research

Cited by 108

Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum

Herzog, C. D., Dass, B., Gasmi, M., Bakay, R., Stansell, J. E., Tuszynski, M., Bankiewicz, K., Chen, E.-Y., Chu, Y., Bishop, K., et al. (2008) · Molecular Therapy

Virus-based gene therapy researchParkinson's Disease Mechanisms and Treatments

Cited by 72

Physical positioning markedly enhances brain transduction after intrathecal AAV9 infusion

Castle, M. J., Cheng, Y., Asokan, A., & Tuszynski, M. H. (2018) · Science Advances

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 41