Grosveld, Frank

Looping and Interaction between Hypersensitive Sites in the Active β-globin Locus

Tolhuis, B., Palstra, R.-J., Splinter, E., Grosveld, F., & de Laat, W. (2002) · Molecular Cell

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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Gata-3 is an essential regulator of mammary-gland morphogenesis and luminal-cell differentiation

Asselin-Labat, M.-L., Sutherland, K. D., Barker, H., Thomas, R., Shackleton, M., Forrest, N. C., Hartley, L., Robb, L., Grosveld, F. G., van der Wees, J., et al. (2007) · Nature Cell Biology

Cancer Cells and MetastasisDevelopmental Biology and Gene Regulation

Cited by 840

Cohesin and CTCF differentially affect chromatin architecture and gene expression in human cells

Zuin, J., Dixon, J. R., van der Reijden, M. I. J. A., Ye, Z., Kolovos, P., Brouwer, R. W. W., van de Corput, M. P. C., van de Werken, H. J. G., Knoch, T. A., van IJcken, W. F. J., et al. (2014) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 779

CTCF mediates long-range chromatin looping and local histone modification in the β-globin locus

Splinter, E., Heath, H., Kooren, J., Palstra, R.-J., Klous, P., Grosveld, F., Galjart, N., & de Laat, W. (2006) · Genes & Development

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 677

The β-globin nuclear compartment in development and erythroid differentiation

Palstra, R.-J., Tolhuis, B., Splinter, E., Nijmeijer, R., Grosveld, F., & de Laat, W. (2003) · Nature Genetics

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 559

Bicaudal-D regulates COPI- independent Golgi-ER transport by recruiting the dynein-dynactin motor complex

Matanis, T., Akhmanova, A., Wulf, P., Del Nery, E., Weide, T., Stepanova, T., Galjart, N., Grosveld, F., Goud, B., De Zeeuw, C. I., et al. (2002) · Nature Cell Biology

Cellular transport and secretionMicrotubule and mitosis dynamics

Cited by 413

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

Borg, J., Papadopoulos, P., Georgitsi, M., Gutiérrez, L., Grech, G., Fanis, P., Phylactides, M., Verkerk, A. J. M. H., van der Spek, P. J., Scerri, C. A., et al. (2010) · Nature Genetics

Hemoglobinopathies and Related DisordersKruppel-like factors research

Cited by 371

Rab6 regulates transport and targeting of exocytotic carriers

Grigoriev, I., Splinter, D., Keijzer, N., Wulf, P. S., Demmers, J., Ohtsuka, T., Modesti, M., Maly, I. V., Grosveld, F., Hoogenraad, C. C., et al. (2007) · Developmental Cell

Cellular transport and secretionExtracellular vesicles in disease

Cited by 361

The active spatial organization of the β-globin locus requires the transcription factor EKLF

Drissen, R., Palstra, R.-J., Gillemans, N., Splinter, E., Grosveld, F., Philipsen, S., & de Laat, W. (2004) · Genes & Development

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 352

The human beta-globin gene 3' enhancer contains multiple binding sites for an erythroid-specific protein.

Wall, L., deBoer, E., & Grosveld, F. (1988) · Genes & Development

Hemoglobinopathies and Related DisordersGenomics and Chromatin Dynamics

Cited by 350

Heterochromatin Effects on the Frequency and Duration of LCR-Mediated Gene Transcription

Milot, E., Strouboulis, J., Trimborn, T., Wijgerde, M., de Boer, E., Langeveld, A., Tan-Un, K., Vergeer, W., Yannoutsos, N., Grosveld, F., et al. (1996) · Cell

Genomics and Chromatin DynamicsNuclear Structure and Function

Cited by 314

MicroRNA-133 Controls Brown Adipose Determination in Skeletal Muscle Satellite Cells by Targeting Prdm16

Yin, H., Pasut, A., Soleimani, V. D., Bentzinger, C. F., Antoun, G., Thorn, S., Seale, P., Fernando, P., van IJcken, W., Grosveld, F., et al. (2013) · Cell Metabolism

Adipose Tissue and MetabolismMuscle Physiology and Disorders

Cited by 293

β-Globin gene inactivation by DNA translocation in γβ-thalassaemi

Kioussis, D., Vanin, E., deLange, T., Flavell, R. A., & Grosveld, F. G. (1983) · Nature

Hemoglobinopathies and Related DisordersGenomics and Chromatin Dynamics

Cited by 264

Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes

Engelen, E., Akinci, U., Bryne, J. C., Hou, J., Gontan, C., Moen, M., Szumska, D., Kockx, C., van IJcken, W., Dekkers, D. H. W., et al. (2011) · Nature Genetics

Congenital Ear and Nasal AnomaliesDevelopmental Biology and Gene Regulation

Cited by 255

The core spliceosome as target and effector of non-canonical ATM signalling

Tresini, M., Warmerdam, D. O., Kolovos, P., Snijder, L., Vrouwe, M. G., Demmers, J. A. A., van IJcken, W. F. J., Grosveld, F. G., Medema, R. H., Hoeijmakers, J. H. J., et al. (2015) · Nature

RNA Research and SplicingDNA Repair Mechanisms

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The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation

Soler, E., Andrieu-Soler, C., de Boer, E., Bryne, J. C., Thongjuea, S., Stadhouders, R., Palstra, R.-J., Stevens, M., Kockx, C., van IJcken, W., et al. (2010) · Genes & Development

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

Cited by 245

PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation

Cruz-Molina, S., Respuela, P., Tebartz, C., Kolovos, P., Nikolic, M., Fueyo, R., van Ijcken, W. F. J., Grosveld, F., Frommolt, P., Bazzi, H., et al. (2017) · Cell Stem Cell

Pluripotent Stem Cells ResearchGenomics and Chromatin Dynamics

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Each hypersensitive site of the human beta-globin locus control region confers a different developmental pattern of expression on the globin genes

Fraser, P., Pruzina, S., Antoniou, M., & Grosveld, F. (1993) · Genes & Development

Hemoglobinopathies and Related DisordersGenomics and Chromatin Dynamics

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Snail regulates MyoD binding-site occupancy to direct enhancer switching and differentiation-specific transcription in myogenesis

Soleimani, V. D., Yin, H., Jahani-Asl, A., Ming, H., Kockx, C. E. M., van Ijcken, W. F. J., Grosveld, F., & Rudnicki, M. A. (2012) · Molecular Cell

Genomics and Chromatin DynamicsMuscle Physiology and Disorders

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Multiple interactions between regulatory regions are required to stabilize an active chromatin hub

Patrinos, G. P., de Krom, M., de Boer, E., Langeveld, A., Imam, A. M. A., Strouboulis, J., de Laat, W., & Grosveld, F. G. (2004) · Genes & Development

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

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Chapter 4 β‐Globin Regulation and Long‐Range Interactions

Palstra, R., de Laat, W., & Grosveld, F. (2008) · Advances in genetics

Genomics and Chromatin DynamicsHemoglobinopathies and Related Disorders

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Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1

van den Berghe, V., Stappers, E., Vandesande, B., Dimidschstein, J., Kroes, R., Francis, A., Conidi, A., Lesage, F., Dries, R., Cazzola, S., et al. (2013) · Neuron

Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal Signaling

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Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends

Dragestein, K. A., van Cappellen, W. A., van Haren, J., Tsibidis, G. D., Akhmanova, A., Knoch, T. A., Grosveld, F., & Galjart, N. (2008) · The Journal of Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

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Transcriptional Regulation by (Super)Enhancers: From Discovery to Mechanisms

Grosveld, F., van Staalduinen, J., & Stadhouders, R. (2021) · Annual Review of Genomics and Human Genetics

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

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